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The map label for this gene is lytT [H]

Identifier: 238925465

GI number: 238925465

Start: 2975696

End: 2976469

Strand: Reverse

Name: lytT [H]

Synonym: EUBREC_3120

Alternate gene names: 238925465

Gene position: 2976469-2975696 (Counterclockwise)

Preceding gene: 238925466

Following gene: 238925463

Centisome position: 86.28

GC content: 32.17

Gene sequence:

>774_bases
ATGCAATACGAAACTATAAGAGCAGCAATATGCGATGATGAAGAATTTTTTCGGAATGAACTTAAAAATTTCGTGAGTGA
ATACGGAAATGAAATGGATATTAATGTAAGCATAGATCTCTATGATAATGCAAAAGAACTCATGAATAATATATTTTCTA
AGAGTAAGGAATATGATTTATTGTTTCTTGATGTGGAAATGCCTGGCATGACAGGTATTGAGATGGCTGATGCATTAAGA
AAAATCGACCCATGGGTATGTATCTCATTTGTGACGAGTTATGATGCATTTGCGATACAGGCATTCAGACTTGATGCACT
TGATTATGTCATGAAACCGATAAAATATACACAGGTAAAGCACATTATCGAAAAAGCAAAAATTCAGATTGATTATCGTA
AAAATGCACAAAAAGCGGAAAAAAGATATCTAAAAATTAAATCCGGATATGAAGATGTTCTCATAGACCTTCAAAATGTA
ATATATATAGAAAAACGCAGAAACCAGTGTGTATTCCATAAAATTGATGAGGAAATAAGCTGTTATGAGCCTTTAAAAAA
TGTATATGAAAGATTGGATAATGATGTATTTATGTATACACATCAGGGGTATATAGCCAATTTTAATTACATTAAAGAAG
TAAAAAAAGATGTGGTATGCTTTGGACGAGGCATGGAGGTTCCTTTGAGCAGGAAATATCATGATCAGATAAAGGAACTT
CATCTGGACAAGATAAGAAGAGCATATAAGGAGCAGGAACTTAACTATAATTAG

Upstream 100 bases:

>100_bases
AGGTAGACCGCGACAATTACATAAATATATGACATTGTAACTGTAAGACGCTTAGAAGGACTGTAAGGTGGTTATAGGGG
GATTTTAAGGAATTTAATAT

Downstream 100 bases:

>100_bases
GGAGTTCTGCCTTTACGCTAAAATATCCGCTGGCATAAGAAAAATCAATGTGTCCGTTAAGGTTGGAAACGACTTTACGG
ACATTTTTTATGCCTATTCC

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MQYETIRAAICDDEEFFRNELKNFVSEYGNEMDINVSIDLYDNAKELMNNIFSKSKEYDLLFLDVEMPGMTGIEMADALR
KIDPWVCISFVTSYDAFAIQAFRLDALDYVMKPIKYTQVKHIIEKAKIQIDYRKNAQKAEKRYLKIKSGYEDVLIDLQNV
IYIEKRRNQCVFHKIDEEISCYEPLKNVYERLDNDVFMYTHQGYIANFNYIKEVKKDVVCFGRGMEVPLSRKYHDQIKEL
HLDKIRRAYKEQELNYN

Sequences:

>Translated_257_residues
MQYETIRAAICDDEEFFRNELKNFVSEYGNEMDINVSIDLYDNAKELMNNIFSKSKEYDLLFLDVEMPGMTGIEMADALR
KIDPWVCISFVTSYDAFAIQAFRLDALDYVMKPIKYTQVKHIIEKAKIQIDYRKNAQKAEKRYLKIKSGYEDVLIDLQNV
IYIEKRRNQCVFHKIDEEISCYEPLKNVYERLDNDVFMYTHQGYIANFNYIKEVKKDVVCFGRGMEVPLSRKYHDQIKEL
HLDKIRRAYKEQELNYN
>Mature_257_residues
MQYETIRAAICDDEEFFRNELKNFVSEYGNEMDINVSIDLYDNAKELMNNIFSKSKEYDLLFLDVEMPGMTGIEMADALR
KIDPWVCISFVTSYDAFAIQAFRLDALDYVMKPIKYTQVKHIIEKAKIQIDYRKNAQKAEKRYLKIKSGYEDVLIDLQNV
IYIEKRRNQCVFHKIDEEISCYEPLKNVYERLDNDVFMYTHQGYIANFNYIKEVKKDVVCFGRGMEVPLSRKYHDQIKEL
HLDKIRRAYKEQELNYN

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG3279

COG function: function code KT; Response regulator of the LytR/AlgR family

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI87082052, Length=248, Percent_Identity=26.2096774193548, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788724, Length=257, Percent_Identity=22.1789883268482, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR007492
- InterPro:   IPR001789 [H]

Pfam domain/function: PF04397 LytTR; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 30690; Mature: 30690

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50930 HTH_LYTTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYETIRAAICDDEEFFRNELKNFVSEYGNEMDINVSIDLYDNAKELMNNIFSKSKEYDL
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHCCCCCCEE
LFLDVEMPGMTGIEMADALRKIDPWVCISFVTSYDAFAIQAFRLDALDYVMKPIKYTQVK
EEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHH
HIIEKAKIQIDYRKNAQKAEKRYLKIKSGYEDVLIDLQNVIYIEKRRNQCVFHKIDEEIS
HHHHHHHEEEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCHHHHHHCCHHH
CYEPLKNVYERLDNDVFMYTHQGYIANFNYIKEVKKDVVCFGRGMEVPLSRKYHDQIKEL
HHHHHHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HLDKIRRAYKEQELNYN
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQYETIRAAICDDEEFFRNELKNFVSEYGNEMDINVSIDLYDNAKELMNNIFSKSKEYDL
CCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEEEEEECCCHHHHHHHHHCCCCCCEE
LFLDVEMPGMTGIEMADALRKIDPWVCISFVTSYDAFAIQAFRLDALDYVMKPIKYTQVK
EEEEEECCCCCCHHHHHHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCHHHHHHH
HIIEKAKIQIDYRKNAQKAEKRYLKIKSGYEDVLIDLQNVIYIEKRRNQCVFHKIDEEIS
HHHHHHHEEEEHHCCHHHHHHHHHHHCCCHHHHHHHHHHHEEEECCCCCHHHHHHCCHHH
CYEPLKNVYERLDNDVFMYTHQGYIANFNYIKEVKKDVVCFGRGMEVPLSRKYHDQIKEL
HHHHHHHHHHHCCCCEEEEEECCEEECHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
HLDKIRRAYKEQELNYN
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]