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The map label for this gene is tig [H]

Identifier: 238925432

GI number: 238925432

Start: 2951677

End: 2952636

Strand: Reverse

Name: tig [H]

Synonym: EUBREC_3087

Alternate gene names: 238925432

Gene position: 2952636-2951677 (Counterclockwise)

Preceding gene: 238925433

Following gene: 238925431

Centisome position: 85.59

GC content: 45.62

Gene sequence:

>960_bases
ATGGACATCGTATTAGGAAATTACAAAGGATTAAAGGCAAACATCCCTTATATTGCATATACAGAGGAGGATGTTAATTC
ACAGATAGCGACACTTCTTTCAGGAAATCCTGTCAGAGAGCAGAAAACAGGCCCGTTAGCAATGGGCGACACGGCAGTAA
TAGACTACGAGGGCTTTAAGGACGGAGTTGCGTTTGAGGGCGGAAAGGCTGAGAAATATCCTCTGGGAATCGGTTCAGGC
TCTTTTATTCCGGGCTTTGAGGAGCAGCTTGTAGGCATGGAAATCGGTGAGGACAGAGACATCAATCTCTCATTCCCTGA
GCAGTATCATGCGCCGGAGCTTGCAGGAAAAGCGGTTGTTTTCAAGGTTAAGCTGCACGAGATTTACAATGAGAAGGAAG
CAGAGCTGAACGATGAGTTTGCAGCATCTCTCAATTTCCCTGAGGTACAGTCAGTGGAGGATTTAAAGAAATATATCAAC
GAGTATCTTGAGTACCAGGTAGAGGCAAGAAAGGCAGATGCGGCAAGAGAAAAGCTCTATGACCAGATTCTTGAGAGCAG
CTCATGTCTTGTTTCGCCACAGGCAGTAGAGACAGCGGTAAATATGCAGCTTCAGCAGATGGCAGCATCATTTGCACAGC
AGGGTGTGGCTATGGAGCAGTATCTTCAGATGACAGGCAAGACTATGGATAGCTTAAAGGATGAACTCAAGCCTGTAGCA
CAGAAGCAGGTAAAGCTTGAGGCTGTTCTCGATGAAATCATCAGAGTGGAAAATATCACTGTATCTGACGAGGAGATGGA
TGAGCAGTATGAGCTTATTTCACAGAAGTATGGTCAGCCTGTTGACGTTGTAAAGCAGGTGATTCCAAAGGCACAGCTCA
AGCCGGATTTACTTCGTATGAAGGCATCACAGCTCATCATCGATGCGGCTGAGATTATCATGGAAGAAAGCGAAAAATAA

Upstream 100 bases:

>100_bases
AATGAGTTTTTATTGGCTTTATTTGGTAACTAGTGTATACTATTTGCATATAACAGCTTAGTTAAGCAGATATAAATACA
CATAAAAGAAAGGTATAATC

Downstream 100 bases:

>100_bases
TGTATAGAATATTTTTGGTTGAGGATGACGAGACCATAGCAAAGCTTGTCAGAAGACATTTGGAAAAATGGGATTATGAT
GTGCATGTGGTGCAGAAATT

Product: trigger factor

Products: peptidylproline (w =0) [C]

Alternate protein names: TF [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MDIVLGNYKGLKANIPYIAYTEEDVNSQIATLLSGNPVREQKTGPLAMGDTAVIDYEGFKDGVAFEGGKAEKYPLGIGSG
SFIPGFEEQLVGMEIGEDRDINLSFPEQYHAPELAGKAVVFKVKLHEIYNEKEAELNDEFAASLNFPEVQSVEDLKKYIN
EYLEYQVEARKADAAREKLYDQILESSSCLVSPQAVETAVNMQLQQMAASFAQQGVAMEQYLQMTGKTMDSLKDELKPVA
QKQVKLEAVLDEIIRVENITVSDEEMDEQYELISQKYGQPVDVVKQVIPKAQLKPDLLRMKASQLIIDAAEIIMEESEK

Sequences:

>Translated_319_residues
MDIVLGNYKGLKANIPYIAYTEEDVNSQIATLLSGNPVREQKTGPLAMGDTAVIDYEGFKDGVAFEGGKAEKYPLGIGSG
SFIPGFEEQLVGMEIGEDRDINLSFPEQYHAPELAGKAVVFKVKLHEIYNEKEAELNDEFAASLNFPEVQSVEDLKKYIN
EYLEYQVEARKADAAREKLYDQILESSSCLVSPQAVETAVNMQLQQMAASFAQQGVAMEQYLQMTGKTMDSLKDELKPVA
QKQVKLEAVLDEIIRVENITVSDEEMDEQYELISQKYGQPVDVVKQVIPKAQLKPDLLRMKASQLIIDAAEIIMEESEK
>Mature_319_residues
MDIVLGNYKGLKANIPYIAYTEEDVNSQIATLLSGNPVREQKTGPLAMGDTAVIDYEGFKDGVAFEGGKAEKYPLGIGSG
SFIPGFEEQLVGMEIGEDRDINLSFPEQYHAPELAGKAVVFKVKLHEIYNEKEAELNDEFAASLNFPEVQSVEDLKKYIN
EYLEYQVEARKADAAREKLYDQILESSSCLVSPQAVETAVNMQLQQMAASFAQQGVAMEQYLQMTGKTMDSLKDELKPVA
QKQVKLEAVLDEIIRVENITVSDEEMDEQYELISQKYGQPVDVVKQVIPKAQLKPDLLRMKASQLIIDAAEIIMEESEK

Specific function: Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation [H]

COG id: COG0544

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786640, Length=269, Percent_Identity=26.7657992565056, Blast_Score=108, Evalue=4e-25,

Paralogues:

None

Copy number: 1070 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 500 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 340 Molecules/Cell In: Growth-Phase, Mini

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR005215
- InterPro:   IPR008880
- InterPro:   IPR008881 [H]

Pfam domain/function: PF00254 FKBP_C; PF05698 Trigger_C; PF05697 Trigger_N [H]

EC number: NA

Molecular weight: Translated: 35605; Mature: 35605

Theoretical pI: Translated: 4.18; Mature: 4.18

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIVLGNYKGLKANIPYIAYTEEDVNSQIATLLSGNPVREQKTGPLAMGDTAVIDYEGFK
CCEEECCCCCCEECCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEECCCCC
DGVAFEGGKAEKYPLGIGSGSFIPGFEEQLVGMEIGEDRDINLSFPEQYHAPELAGKAVV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHCCHHHCCCEEE
FKVKLHEIYNEKEAELNDEFAASLNFPEVQSVEDLKKYINEYLEYQVEARKADAAREKLY
EEEHHHHHHCHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQILESSSCLVSPQAVETAVNMQLQQMAASFAQQGVAMEQYLQMTGKTMDSLKDELKPVA
HHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKQVKLEAVLDEIIRVENITVSDEEMDEQYELISQKYGQPVDVVKQVIPKAQLKPDLLRM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
KASQLIIDAAEIIMEESEK
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDIVLGNYKGLKANIPYIAYTEEDVNSQIATLLSGNPVREQKTGPLAMGDTAVIDYEGFK
CCEEECCCCCCEECCCEEEECHHHHHHHHHHHHCCCCCCCCCCCCEECCCEEEEECCCCC
DGVAFEGGKAEKYPLGIGSGSFIPGFEEQLVGMEIGEDRDINLSFPEQYHAPELAGKAVV
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCHHHCCHHHCCCEEE
FKVKLHEIYNEKEAELNDEFAASLNFPEVQSVEDLKKYINEYLEYQVEARKADAAREKLY
EEEHHHHHHCHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DQILESSSCLVSPQAVETAVNMQLQQMAASFAQQGVAMEQYLQMTGKTMDSLKDELKPVA
HHHHCCCCCEECHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH
QKQVKLEAVLDEIIRVENITVSDEEMDEQYELISQKYGQPVDVVKQVIPKAQLKPDLLRM
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
KASQLIIDAAEIIMEESEK
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: peptidylproline (w =180) [C]

Specific reaction: peptidylproline (w =180) = peptidylproline (w =0) [C]

General reaction: Isomerases; cis-trans-Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA