| Definition | Eubacterium rectale ATCC 33656, complete genome. |
|---|---|
| Accession | NC_012781 |
| Length | 3,449,685 |
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The map label for this gene is relA [H]
Identifier: 238925277
GI number: 238925277
Start: 2812918
End: 2815278
Strand: Reverse
Name: relA [H]
Synonym: EUBREC_2931
Alternate gene names: 238925277
Gene position: 2815278-2812918 (Counterclockwise)
Preceding gene: 238925278
Following gene: 238925276
Centisome position: 81.61
GC content: 48.24
Gene sequence:
>2361_bases GTGAGACTATTGGCAGATTACTCAACAGAAGAATTAGAAAAAATAGCGGACAAATTTCGCTCAGATACCAGCGGTATAAG GGGAACAAAGGATTTTACGAGCCCGGAGGAGCTTTACGATGAGCTGAAAAAGGAAATCAAAAAGTACCATCCGTCGGATG ATACGAGCCTTGTGGACAAAGCCTACAGGGTAGCTTATGATGCTCATAAGGGTCAGGCACGTAAGTCAGGAGAGCCTTAT ATCATACATCCGCTTTGTGTTGCCATAATACTCGCCGAGCTCGAGCTGGATAAGGAAACAATTGCAGCAGGTCTGCTCCA TGATGTGCTGGAGGACACTATCATGACCATGGATGAGATGCGTGCAGAATTTGGAGACGATGTCGCACATCTGGTGGATG GTGTCACGAAGTTAAAGCACCTGCATCTGACAGACAGCACCAAGGATCCGAAGGATAAGAATGCGGACAGGCTTGAGATG CAGGCTGAGAATCTGCGCAAGATGTTTCTCGCCATGGCAAAGGATATCAGGGTCATCCTCATAAAGCTGGCAGACAGACT GCACAATATGCGTACACTCAAGTACCAGTCCAAGGAGGCACAGCAGCGTATCGCCAGAGAGACACAGGATATCTACTGCC CTATCGCACAGCGACTTGGTATCAGCAAGATAAAGATAGAGCTCGAGGACCTTTGTATGAAGTACCTCTATCCGGATGCC TACTACGATCTGGTAGAGAAAGTAGCCCTCAGAAAGACAGAACGTGACACCTACATCCAGGGCCTGGTAAACGATGTCAA GAAGTATGTTTCGGATGCCGGCATCAAGGCTGAGATATACGGCAGGGCAAAGCATTTCTTCAGTATATATAAGAAGATGG TCAATCAGGACAAGACTATAGACCAGATATATGATCTATTTGCCATCAGGATTCTGGTGGATACAATACCGGACTGCTAC GCAGTGCTTGGTATCATACATGAGAAGTATAAGCCTATACCGGGTCGTTTCAAGGACTATATCGCCATGCCGAAGCAGAA CATGTACCAGTCGCTTCACACGACACTCATAGGCCCGAGCGGACAGCCGTTTGAGATACAGATTCGTACCTACGAGATGC ATCGTACTGCTGAGTACGGTATCGCAGCGCACTGGAAGTACAAGGAAACAAACAACGGCAATGCCACTACCACCACTGTC ACAGAGGAGGAGAAGCTCAGCTGGCTGCGCCAGATACTCGAGTGGCAGCAGGATATGTCGGATAATAAGGAGTTTATGAC TTTATTAAAGAGTGATTTAAATTTATTCTCCGACAATGTATTTGCATTCACTCCATCCGGCGATGTAAAGAACCTGCCAA AGGGCTCCACACCTATAGACTTTGCCTACAGCATACATTCTGCGGTCGGCAACAAGATGGTCGGTGCCAAGGTAAACGGC AAGCTGGTGCCGATAGACTATGTCATCAAAAACGGTGACCAGATAGAGATAATCACCTCACAGAACTCCAAGGGACCAAG CCGTGACTGGCTCAAGGTCGTAAAGAGCACACAGGCTAAGAACAAGATCAACCAGTGGTTCAGAAGTGAGCTCAAGGAGG AGAATATACAGCACGGCAAGGATCTGATAGCAGCCTATGCCAAGGCAAAGGGCATCAACTTTGCTGAGATAAACAAGCCT GAGTATCAGGAGAAAATACGCCGCAAATACGGTTTCCACGACTGGAACTCATGCCTTGCAACCGTCGGCCACGGCGGACT CAAGGAGAGCCAGATAGTCAACAGGATGTACGATGAGTACAAGAAGGATCATGTGGTGCCGGTGACAGATGCAGATGTGC TTGGCAGCATCGCAGAAAAGCAGCAGGCGGCAGCAGGCACACAGCCCGAGCACAAGTCAAAGAGCGGTATTGTGGTACAC GGACTCTATGACGTGGCTGTGCACTTCTCGAAGTGCTGCAATCCTGTTCCGGGAGATGAAATCGTGGGCTTTGTCACAAG AGGCCGAGGCATCTCCATCCACAGGACAGACTGCGTGAATATCATCAATCTGTCCAAGATAGAAAAGGACAGGCTCATAG AAGCAGAGTGGCAGGATACAGCCCTCATGGACAACGGTGCCGAGTATCAGGCAGACTTAAAGATATTCTGTCATGACAGG CCGGGACTGCTCGTAGATATCACAAAGATATTTACCGAGAAGGAAATCAATATCAGTGGTATACAGTCCAAGACCAGCAA GCAGGGTATCGCTACAATCGAGGTATTTTTTAATATCAAAGGCAGGGACCAGATAAAGGTTCTCGTGGAGAAGCTCAGAC AGATAGAAAGTGTAATAGACGTAGAGAGGACCACCGGCTAA
Upstream 100 bases:
>100_bases CATGTATGGCGGAGTAAAGATGGTTATCGGCTAACAACATAAGATTGCAATTTTTAAAGAAATAAAATATAATGGCTACT AAAGATACACTACAATCGAG
Downstream 100 bases:
>100_bases ATCCCGGTGGTTCTTGCGTGAAGCATAACATATAACAGACAAGGAGTACACTCATATGGTAAATATGAAGATAGACCACT TCGTAGTGGGACCGGTGCAG
Product: (p)ppGpp synthetase I, SpoT/RelA
Products: NA
Alternate protein names: (p)ppGpp synthase; ATP:GTP 3'-pyrophosphotransferase; ppGpp synthase I [H]
Number of amino acids: Translated: 786; Mature: 786
Protein sequence:
>786_residues MRLLADYSTEELEKIADKFRSDTSGIRGTKDFTSPEELYDELKKEIKKYHPSDDTSLVDKAYRVAYDAHKGQARKSGEPY IIHPLCVAIILAELELDKETIAAGLLHDVLEDTIMTMDEMRAEFGDDVAHLVDGVTKLKHLHLTDSTKDPKDKNADRLEM QAENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYQSKEAQQRIARETQDIYCPIAQRLGISKIKIELEDLCMKYLYPDA YYDLVEKVALRKTERDTYIQGLVNDVKKYVSDAGIKAEIYGRAKHFFSIYKKMVNQDKTIDQIYDLFAIRILVDTIPDCY AVLGIIHEKYKPIPGRFKDYIAMPKQNMYQSLHTTLIGPSGQPFEIQIRTYEMHRTAEYGIAAHWKYKETNNGNATTTTV TEEEKLSWLRQILEWQQDMSDNKEFMTLLKSDLNLFSDNVFAFTPSGDVKNLPKGSTPIDFAYSIHSAVGNKMVGAKVNG KLVPIDYVIKNGDQIEIITSQNSKGPSRDWLKVVKSTQAKNKINQWFRSELKEENIQHGKDLIAAYAKAKGINFAEINKP EYQEKIRRKYGFHDWNSCLATVGHGGLKESQIVNRMYDEYKKDHVVPVTDADVLGSIAEKQQAAAGTQPEHKSKSGIVVH GLYDVAVHFSKCCNPVPGDEIVGFVTRGRGISIHRTDCVNIINLSKIEKDRLIEAEWQDTALMDNGAEYQADLKIFCHDR PGLLVDITKIFTEKEINISGIQSKTSKQGIATIEVFFNIKGRDQIKVLVEKLRQIESVIDVERTTG
Sequences:
>Translated_786_residues MRLLADYSTEELEKIADKFRSDTSGIRGTKDFTSPEELYDELKKEIKKYHPSDDTSLVDKAYRVAYDAHKGQARKSGEPY IIHPLCVAIILAELELDKETIAAGLLHDVLEDTIMTMDEMRAEFGDDVAHLVDGVTKLKHLHLTDSTKDPKDKNADRLEM QAENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYQSKEAQQRIARETQDIYCPIAQRLGISKIKIELEDLCMKYLYPDA YYDLVEKVALRKTERDTYIQGLVNDVKKYVSDAGIKAEIYGRAKHFFSIYKKMVNQDKTIDQIYDLFAIRILVDTIPDCY AVLGIIHEKYKPIPGRFKDYIAMPKQNMYQSLHTTLIGPSGQPFEIQIRTYEMHRTAEYGIAAHWKYKETNNGNATTTTV TEEEKLSWLRQILEWQQDMSDNKEFMTLLKSDLNLFSDNVFAFTPSGDVKNLPKGSTPIDFAYSIHSAVGNKMVGAKVNG KLVPIDYVIKNGDQIEIITSQNSKGPSRDWLKVVKSTQAKNKINQWFRSELKEENIQHGKDLIAAYAKAKGINFAEINKP EYQEKIRRKYGFHDWNSCLATVGHGGLKESQIVNRMYDEYKKDHVVPVTDADVLGSIAEKQQAAAGTQPEHKSKSGIVVH GLYDVAVHFSKCCNPVPGDEIVGFVTRGRGISIHRTDCVNIINLSKIEKDRLIEAEWQDTALMDNGAEYQADLKIFCHDR PGLLVDITKIFTEKEINISGIQSKTSKQGIATIEVFFNIKGRDQIKVLVEKLRQIESVIDVERTTG >Mature_786_residues MRLLADYSTEELEKIADKFRSDTSGIRGTKDFTSPEELYDELKKEIKKYHPSDDTSLVDKAYRVAYDAHKGQARKSGEPY IIHPLCVAIILAELELDKETIAAGLLHDVLEDTIMTMDEMRAEFGDDVAHLVDGVTKLKHLHLTDSTKDPKDKNADRLEM QAENLRKMFLAMAKDIRVILIKLADRLHNMRTLKYQSKEAQQRIARETQDIYCPIAQRLGISKIKIELEDLCMKYLYPDA YYDLVEKVALRKTERDTYIQGLVNDVKKYVSDAGIKAEIYGRAKHFFSIYKKMVNQDKTIDQIYDLFAIRILVDTIPDCY AVLGIIHEKYKPIPGRFKDYIAMPKQNMYQSLHTTLIGPSGQPFEIQIRTYEMHRTAEYGIAAHWKYKETNNGNATTTTV TEEEKLSWLRQILEWQQDMSDNKEFMTLLKSDLNLFSDNVFAFTPSGDVKNLPKGSTPIDFAYSIHSAVGNKMVGAKVNG KLVPIDYVIKNGDQIEIITSQNSKGPSRDWLKVVKSTQAKNKINQWFRSELKEENIQHGKDLIAAYAKAKGINFAEINKP EYQEKIRRKYGFHDWNSCLATVGHGGLKESQIVNRMYDEYKKDHVVPVTDADVLGSIAEKQQAAAGTQPEHKSKSGIVVH GLYDVAVHFSKCCNPVPGDEIVGFVTRGRGISIHRTDCVNIINLSKIEKDRLIEAEWQDTALMDNGAEYQADLKIFCHDR PGLLVDITKIFTEKEINISGIQSKTSKQGIATIEVFFNIKGRDQIKVLVEKLRQIESVIDVERTTG
Specific function: In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. This enzyme catalyzes the formation of pppGpp which i
COG id: COG0317
COG function: function code TK; Guanosine polyphosphate pyrophosphohydrolases/synthetases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 HD domain [H]
Homologues:
Organism=Escherichia coli, GI1789147, Length=708, Percent_Identity=37.5706214689266, Blast_Score=522, Evalue=1e-149, Organism=Escherichia coli, GI1790082, Length=749, Percent_Identity=38.3177570093458, Blast_Score=514, Evalue=1e-147, Organism=Caenorhabditis elegans, GI25143118, Length=147, Percent_Identity=36.0544217687075, Blast_Score=69, Evalue=1e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002912 - InterPro: IPR012675 - InterPro: IPR003607 - InterPro: IPR007685 - InterPro: IPR004811 - InterPro: IPR004095 - InterPro: IPR012676 [H]
Pfam domain/function: PF01842 ACT; PF04607 RelA_SpoT; PF02824 TGS [H]
EC number: =2.7.6.5 [H]
Molecular weight: Translated: 89554; Mature: 89554
Theoretical pI: Translated: 7.13; Mature: 7.13
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.3 %Met (Translated Protein) 3.4 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.3 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRLLADYSTEELEKIADKFRSDTSGIRGTKDFTSPEELYDELKKEIKKYHPSDDTSLVDK CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH AYRVAYDAHKGQARKSGEPYIIHPLCVAIILAELELDKETIAAGLLHDVLEDTIMTMDEM HHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH RAEFGDDVAHLVDGVTKLKHLHLTDSTKDPKDKNADRLEMQAENLRKMFLAMAKDIRVIL HHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH IKLADRLHNMRTLKYQSKEAQQRIARETQDIYCPIAQRLGISKIKIELEDLCMKYLYPDA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHCCHH YYDLVEKVALRKTERDTYIQGLVNDVKKYVSDAGIKAEIYGRAKHFFSIYKKMVNQDKTI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHH DQIYDLFAIRILVDTIPDCYAVLGIIHEKYKPIPGRFKDYIAMPKQNMYQSLHTTLIGPS HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHEECCC GQPFEIQIRTYEMHRTAEYGIAAHWKYKETNNGNATTTTVTEEEKLSWLRQILEWQQDMS CCCEEEEEEEEEEHHHHCCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHCCC DNKEFMTLLKSDLNLFSDNVFAFTPSGDVKNLPKGSTPIDFAYSIHSAVGNKMVGAKVNG CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECEECCC KLVPIDYVIKNGDQIEIITSQNSKGPSRDWLKVVKSTQAKNKINQWFRSELKEENIQHGK EEEEEEHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DLIAAYAKAKGINFAEINKPEYQEKIRRKYGFHDWNSCLATVGHGGLKESQIVNRMYDEY HHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH KKDHVVPVTDADVLGSIAEKQQAAAGTQPEHKSKSGIVVHGLYDVAVHFSKCCNPVPGDE CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHH IVGFVTRGRGISIHRTDCVNIINLSKIEKDRLIEAEWQDTALMDNGAEYQADLKIFCHDR HEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEEEEECC PGLLVDITKIFTEKEINISGIQSKTSKQGIATIEVFFNIKGRDQIKVLVEKLRQIESVID CCCEEEHHHHHHHCCCCCCCCCCHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH VERTTG HHHCCC >Mature Secondary Structure MRLLADYSTEELEKIADKFRSDTSGIRGTKDFTSPEELYDELKKEIKKYHPSDDTSLVDK CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHH AYRVAYDAHKGQARKSGEPYIIHPLCVAIILAELELDKETIAAGLLHDVLEDTIMTMDEM HHHHHHHHHCCCCCCCCCCEEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHH RAEFGDDVAHLVDGVTKLKHLHLTDSTKDPKDKNADRLEMQAENLRKMFLAMAKDIRVIL HHHHCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH IKLADRLHNMRTLKYQSKEAQQRIARETQDIYCPIAQRLGISKIKIELEDLCMKYLYPDA HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEHHHHHHHHHCCHH YYDLVEKVALRKTERDTYIQGLVNDVKKYVSDAGIKAEIYGRAKHFFSIYKKMVNQDKTI HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHH DQIYDLFAIRILVDTIPDCYAVLGIIHEKYKPIPGRFKDYIAMPKQNMYQSLHTTLIGPS HHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHEECCC GQPFEIQIRTYEMHRTAEYGIAAHWKYKETNNGNATTTTVTEEEKLSWLRQILEWQQDMS CCCEEEEEEEEEEHHHHCCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHHHHHHHHCCC DNKEFMTLLKSDLNLFSDNVFAFTPSGDVKNLPKGSTPIDFAYSIHSAVGNKMVGAKVNG CCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCEECEECCC KLVPIDYVIKNGDQIEIITSQNSKGPSRDWLKVVKSTQAKNKINQWFRSELKEENIQHGK EEEEEEHEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH DLIAAYAKAKGINFAEINKPEYQEKIRRKYGFHDWNSCLATVGHGGLKESQIVNRMYDEY HHHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHH KKDHVVPVTDADVLGSIAEKQQAAAGTQPEHKSKSGIVVHGLYDVAVHFSKCCNPVPGDE CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHCCCCCCHH IVGFVTRGRGISIHRTDCVNIINLSKIEKDRLIEAEWQDTALMDNGAEYQADLKIFCHDR HEEEEECCCCCEEECCCHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCCEEEEEEEEECC PGLLVDITKIFTEKEINISGIQSKTSKQGIATIEVFFNIKGRDQIKVLVEKLRQIESVID CCCEEEHHHHHHHCCCCCCCCCCHHCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHH VERTTG HHHCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 9383190; 9384377 [H]