Click here to switch to the map view.

The map label for this gene is nagB [H]

Identifier: 238925273

GI number: 238925273

Start: 2809216

End: 2810124

Strand: Reverse

Name: nagB [H]

Synonym: EUBREC_2927

Alternate gene names: 238925273

Gene position: 2810124-2809216 (Counterclockwise)

Preceding gene: 238925274

Following gene: 238925272

Centisome position: 81.46

GC content: 42.24

Gene sequence:

>909_bases
ATGCAATTTTACCACTTCACCGCATTAAAATTTAATGTTTTTTTTATAAAATATGCAAAATATGACAAAAAGTACTGGAC
AAAATGTCCTATACGAGGTAAAATGCATATATGCAATCAAGCAGCACATTTGAAGGTTGTGCAGATAGTATTGGGTATAT
TTTACGAATTGGGGGGATTTTTCATGAGAATATATCAGGCTAAGGATTATGCAGATATGAGCAGAAAGGCTGCAAATATC
GTATCGGCACAGGTGATTATGAAGCCTAATTGTGTATTGGGACTGGCTACAGGCTCTACACCTATCGGCTTGTATAAGCA
GCTCGTTGAGTGGTTCAAGAAGGGGGATTTGGACTTCTCAGAGGTTATGACGGTGAACCTTGATGAGTACAAGGGATTAA
GCCGTGAGAATGACCAGAGCTACTATTATTTTATGCATCAGAATTTGTTTGATCATGTGAATATTCCAGTTGAGAATACT
CACCTGCCAAACGGCATGGAGCCGGATTCACAGAAGGAGTGCAAGCGCTACACAGAGCTGATTCAGTCTCTTGGCGGTGT
TGATTTACAGCTTCTTGGTATCGGGCACAATGGTCATATCGGTTTTAATGAGCCGGGCGAGTCTTTTGACAAGCAGGTAC
ACTGTGTGAATCTTACAGAGTCTACTATTGAAGCTAATAAGCGCTTCTTTGCATCGGCTGATGATGTTCCGAAGCAGGCT
TATACAATGGGCATCAAGACCATCATGCAGGCTAAGAAGATTCTTATTGTTGCAAGTGGTGAGGATAAGGCAGAGATTGT
GCACAAGGCTTTCTTTGGACCGATTACACCACAGGTGCCGGCTTCTGTATTGCAGCTGCACAATGATGTTACGCTTGTAG
CGGATGAGGCTGCACTGAGTTATTTGTAG

Upstream 100 bases:

>100_bases
TTATTGTTCTGTAATGTGATTAATCTTAACTTTGAACTATAACTAAGAAAAGCAAGCAATATTCATACACGGTGAAAGAG
CTCTCTTGAAGCGAATTTTT

Downstream 100 bases:

>100_bases
ATGTTTTTTAGTTGAGAAGGTACATGTATATGATAATAAAAAATGCAAGGGTATTTACAGAGGATGGCAGCTTTATGCAA
GGCGATGTTGTCGTTAAGGA

Product: glucosamine-6-phosphate deaminase

Products: NA

Alternate protein names: GlcN6P deaminase; GNPDA; Glucosamine-6-phosphate isomerase [H]

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MQFYHFTALKFNVFFIKYAKYDKKYWTKCPIRGKMHICNQAAHLKVVQIVLGIFYELGGFFMRIYQAKDYADMSRKAANI
VSAQVIMKPNCVLGLATGSTPIGLYKQLVEWFKKGDLDFSEVMTVNLDEYKGLSRENDQSYYYFMHQNLFDHVNIPVENT
HLPNGMEPDSQKECKRYTELIQSLGGVDLQLLGIGHNGHIGFNEPGESFDKQVHCVNLTESTIEANKRFFASADDVPKQA
YTMGIKTIMQAKKILIVASGEDKAEIVHKAFFGPITPQVPASVLQLHNDVTLVADEAALSYL

Sequences:

>Translated_302_residues
MQFYHFTALKFNVFFIKYAKYDKKYWTKCPIRGKMHICNQAAHLKVVQIVLGIFYELGGFFMRIYQAKDYADMSRKAANI
VSAQVIMKPNCVLGLATGSTPIGLYKQLVEWFKKGDLDFSEVMTVNLDEYKGLSRENDQSYYYFMHQNLFDHVNIPVENT
HLPNGMEPDSQKECKRYTELIQSLGGVDLQLLGIGHNGHIGFNEPGESFDKQVHCVNLTESTIEANKRFFASADDVPKQA
YTMGIKTIMQAKKILIVASGEDKAEIVHKAFFGPITPQVPASVLQLHNDVTLVADEAALSYL
>Mature_302_residues
MQFYHFTALKFNVFFIKYAKYDKKYWTKCPIRGKMHICNQAAHLKVVQIVLGIFYELGGFFMRIYQAKDYADMSRKAANI
VSAQVIMKPNCVLGLATGSTPIGLYKQLVEWFKKGDLDFSEVMTVNLDEYKGLSRENDQSYYYFMHQNLFDHVNIPVENT
HLPNGMEPDSQKECKRYTELIQSLGGVDLQLLGIGHNGHIGFNEPGESFDKQVHCVNLTESTIEANKRFFASADDVPKQA
YTMGIKTIMQAKKILIVASGEDKAEIVHKAFFGPITPQVPASVLQLHNDVTLVADEAALSYL

Specific function: Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion [H]

COG id: COG0363

COG function: function code G; 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily [H]

Homologues:

Organism=Homo sapiens, GI13027378, Length=243, Percent_Identity=39.917695473251, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI19923881, Length=243, Percent_Identity=38.2716049382716, Blast_Score=164, Evalue=6e-41,
Organism=Escherichia coli, GI1786893, Length=227, Percent_Identity=43.1718061674009, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1789530, Length=226, Percent_Identity=31.858407079646, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI48994958, Length=235, Percent_Identity=29.7872340425532, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17554876, Length=232, Percent_Identity=40.948275862069, Blast_Score=186, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24581960, Length=208, Percent_Identity=42.3076923076923, Blast_Score=179, Evalue=2e-45,
Organism=Drosophila melanogaster, GI19920764, Length=208, Percent_Identity=42.3076923076923, Blast_Score=179, Evalue=2e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006148
- InterPro:   IPR004547
- InterPro:   IPR018321 [H]

Pfam domain/function: PF01182 Glucosamine_iso [H]

EC number: =3.5.99.6 [H]

Molecular weight: Translated: 34214; Mature: 34214

Theoretical pI: Translated: 7.34; Mature: 7.34

Prosite motif: PS01161 GLC_GALNAC_ISOMERASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFYHFTALKFNVFFIKYAKYDKKYWTKCPIRGKMHICNQAAHLKVVQIVLGIFYELGGF
CCEEEEEEEEEEEEEEEEEHHCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHH
FMRIYQAKDYADMSRKAANIVSAQVIMKPNCVLGLATGSTPIGLYKQLVEWFKKGDLDFS
HHHHHHHCCHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHH
EVMTVNLDEYKGLSRENDQSYYYFMHQNLFDHVNIPVENTHLPNGMEPDSQKECKRYTEL
HEEEEEHHHHCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
IQSLGGVDLQLLGIGHNGHIGFNEPGESFDKQVHCVNLTESTIEANKRFFASADDVPKQA
HHHCCCCEEEEEEECCCCCCCCCCCCHHHCCEEEEEECCHHHHHHCHHEECCCCCCCHHH
YTMGIKTIMQAKKILIVASGEDKAEIVHKAFFGPITPQVPASVLQLHNDVTLVADEAALS
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECHHHHC
YL
CC
>Mature Secondary Structure
MQFYHFTALKFNVFFIKYAKYDKKYWTKCPIRGKMHICNQAAHLKVVQIVLGIFYELGGF
CCEEEEEEEEEEEEEEEEEHHCCHHHHCCCCCCCHHHHCHHHHHHHHHHHHHHHHHHHHH
FMRIYQAKDYADMSRKAANIVSAQVIMKPNCVLGLATGSTPIGLYKQLVEWFKKGDLDFS
HHHHHHHCCHHHHHHHHHHHHHEEEEECCCEEEEEECCCCCHHHHHHHHHHHHHCCCCHH
EVMTVNLDEYKGLSRENDQSYYYFMHQNLFDHVNIPVENTHLPNGMEPDSQKECKRYTEL
HEEEEEHHHHCCCCCCCCCCEEEEEECCCHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHH
IQSLGGVDLQLLGIGHNGHIGFNEPGESFDKQVHCVNLTESTIEANKRFFASADDVPKQA
HHHCCCCEEEEEEECCCCCCCCCCCCHHHCCEEEEEECCHHHHHHCHHEECCCCCCCHHH
YTMGIKTIMQAKKILIVASGEDKAEIVHKAFFGPITPQVPASVLQLHNDVTLVADEAALS
HHHHHHHHHCCCEEEEEECCCCHHHHHHHHHCCCCCCCHHHHHHHHCCCEEEEECHHHHC
YL
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA