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The map label for this gene is nagA [H]

Identifier: 238925272

GI number: 238925272

Start: 2808032

End: 2809192

Strand: Reverse

Name: nagA [H]

Synonym: EUBREC_2926

Alternate gene names: 238925272

Gene position: 2809192-2808032 (Counterclockwise)

Preceding gene: 238925273

Following gene: 238925271

Centisome position: 81.43

GC content: 46.68

Gene sequence:

>1161_bases
ATGTATATGATAATAAAAAATGCAAGGGTATTTACAGAGGATGGCAGCTTTATGCAAGGCGATGTTGTCGTTAAGGATGG
CCGTTTTGACAGTGTTTTGGAGAGAACAGCTGACACGGACGCGGCTAATGACAGCGAATCGCAGGAGATTATAGATGCAT
CAGGTCTTATCATGATACCGGGTCTTGTGGATATTCATTTTCATGGATGCAAGGGAGCTGATATGTGTGACGGTACCACA
GAGGCACTTGATGTGATTACAGCATACGAGGCTTCTGTCGGAGTGACGAGCGTGTGTCCAGCTACTATGACCATTCAAAG
GGATGAGCTTTTGAGTGTCATGAAAAATGCCGGTGATTATAATTATCATGGTGGTGCACATCTTGTAGGTATCAATATGG
AGGGACCTTTTATCAGTCCTTCTAAAAAGGGCGCACAGGCGGCAGAGAATATCATGCGATGTGATTATGATTATTTCTGT
GAGCTTCAGGATGCGGCCCATGGCTTGATAAAGCTTGTAGATATCGCTCCGGAGGAGCCGGGCGCGATTGATTTTATAGA
CAGGGTAAGAGGAAGTGTTGTGGTTTCAATAGCACACACAGCGGCTGATTATGACACCGCAGTAGAGGCTATTGAGCATG
GTGCAAGCCATGCTACACATTTGTATAATGCGATGCCACCGCTTCATCACAGGAATCCGGGAGTTATCGGGGCTGTGAGA
GATTCAAAAAAGTGTCATGCAGAGCTCATTTGTGACGGTGTGCATATTCATCCGTCGGTTATCAGGGCGACATTTGCCAT
GTTTGGGGCTGAGCGCATGATTTTAATAAGTGACAGCATGAGAGCCACAGGGCTTGAGGATGGCGAGTATACACTCGGTG
GACAGGCAGTGACAGTCAGAGGTCCGCTTGCCACACTCCATGATGGGACAATTGCCGGTTCGGCAACCAATCTGATGGAT
TGTATGCGTTTCACAGTAAGGCAGGCAGGTATTCCGCTTGAGGAGGCAATTATGTGTGCTACAGCCAATCCGGCTAAGGA
GATTGGCATCTATGATGAAGCAGGCAGCATTTCTGCAGGAAAGAGAGCAGATTTTGTGCTTCTCAATGATGATTTGGATA
TTGTGAGTGTGTATATCGACGGAAAGGAGATATCATGTTAG

Upstream 100 bases:

>100_bases
AGGTGCCGGCTTCTGTATTGCAGCTGCACAATGATGTTACGCTTGTAGCGGATGAGGCTGCACTGAGTTATTTGTAGATG
TTTTTTAGTTGAGAAGGTAC

Downstream 100 bases:

>100_bases
GTTTTTTCAAGAATAAGTCAAAGGGAAAGGTGATCTGTTCTCCGTGCAACGGTAGAGTGGTTCCTATTACAGAGGTTCCG
GATCCTACTTTTTCTGAGAA

Product: N-acetylglucosamine-6-phosphate deacetylase

Products: NA

Alternate protein names: GlcNAc 6-P deacetylase [H]

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MYMIIKNARVFTEDGSFMQGDVVVKDGRFDSVLERTADTDAANDSESQEIIDASGLIMIPGLVDIHFHGCKGADMCDGTT
EALDVITAYEASVGVTSVCPATMTIQRDELLSVMKNAGDYNYHGGAHLVGINMEGPFISPSKKGAQAAENIMRCDYDYFC
ELQDAAHGLIKLVDIAPEEPGAIDFIDRVRGSVVVSIAHTAADYDTAVEAIEHGASHATHLYNAMPPLHHRNPGVIGAVR
DSKKCHAELICDGVHIHPSVIRATFAMFGAERMILISDSMRATGLEDGEYTLGGQAVTVRGPLATLHDGTIAGSATNLMD
CMRFTVRQAGIPLEEAIMCATANPAKEIGIYDEAGSISAGKRADFVLLNDDLDIVSVYIDGKEISC

Sequences:

>Translated_386_residues
MYMIIKNARVFTEDGSFMQGDVVVKDGRFDSVLERTADTDAANDSESQEIIDASGLIMIPGLVDIHFHGCKGADMCDGTT
EALDVITAYEASVGVTSVCPATMTIQRDELLSVMKNAGDYNYHGGAHLVGINMEGPFISPSKKGAQAAENIMRCDYDYFC
ELQDAAHGLIKLVDIAPEEPGAIDFIDRVRGSVVVSIAHTAADYDTAVEAIEHGASHATHLYNAMPPLHHRNPGVIGAVR
DSKKCHAELICDGVHIHPSVIRATFAMFGAERMILISDSMRATGLEDGEYTLGGQAVTVRGPLATLHDGTIAGSATNLMD
CMRFTVRQAGIPLEEAIMCATANPAKEIGIYDEAGSISAGKRADFVLLNDDLDIVSVYIDGKEISC
>Mature_386_residues
MYMIIKNARVFTEDGSFMQGDVVVKDGRFDSVLERTADTDAANDSESQEIIDASGLIMIPGLVDIHFHGCKGADMCDGTT
EALDVITAYEASVGVTSVCPATMTIQRDELLSVMKNAGDYNYHGGAHLVGINMEGPFISPSKKGAQAAENIMRCDYDYFC
ELQDAAHGLIKLVDIAPEEPGAIDFIDRVRGSVVVSIAHTAADYDTAVEAIEHGASHATHLYNAMPPLHHRNPGVIGAVR
DSKKCHAELICDGVHIHPSVIRATFAMFGAERMILISDSMRATGLEDGEYTLGGQAVTVRGPLATLHDGTIAGSATNLMD
CMRFTVRQAGIPLEEAIMCATANPAKEIGIYDEAGSISAGKRADFVLLNDDLDIVSVYIDGKEISC

Specific function: N-acetylglucosamine utilization. [C]

COG id: COG1820

COG function: function code G; N-acetylglucosamine-6-phosphate deacetylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nagA family [H]

Homologues:

Organism=Homo sapiens, GI21361513, Length=430, Percent_Identity=28.1395348837209, Blast_Score=159, Evalue=3e-39,
Organism=Homo sapiens, GI224922791, Length=431, Percent_Identity=28.0742459396752, Blast_Score=159, Evalue=4e-39,
Organism=Escherichia coli, GI1786892, Length=395, Percent_Identity=28.3544303797468, Blast_Score=157, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI17553768, Length=392, Percent_Identity=31.1224489795918, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI19920392, Length=387, Percent_Identity=31.0077519379845, Blast_Score=166, Evalue=2e-41,
Organism=Drosophila melanogaster, GI281361140, Length=400, Percent_Identity=30, Blast_Score=161, Evalue=7e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR003764
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.1.25 [H]

Molecular weight: Translated: 41301; Mature: 41301

Theoretical pI: Translated: 4.47; Mature: 4.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.7 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYMIIKNARVFTEDGSFMQGDVVVKDGRFDSVLERTADTDAANDSESQEIIDASGLIMIP
CEEEEECCEEEECCCCEEECCEEEECCCHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEC
GLVDIHFHGCKGADMCDGTTEALDVITAYEASVGVTSVCPATMTIQRDELLSVMKNAGDY
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEECHHHHHHHHHCCCCC
NYHGGAHLVGINMEGPFISPSKKGAQAAENIMRCDYDYFCELQDAAHGLIKLVDIAPEEP
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHCCEEEEEEECCCCC
GAIDFIDRVRGSVVVSIAHTAADYDTAVEAIEHGASHATHLYNAMPPLHHRNPGVIGAVR
CCCHHHHHCCCEEEEEEEHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEEEEC
DSKKCHAELICDGVHIHPSVIRATFAMFGAERMILISDSMRATGLEDGEYTLGGQAVTVR
CCCHHCHHHEECCCEECHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCEEEEEE
GPLATLHDGTIAGSATNLMDCMRFTVRQAGIPLEEAIMCATANPAKEIGIYDEAGSISAG
CCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHCCCCCCCCCCCCC
KRADFVLLNDDLDIVSVYIDGKEISC
CCCCEEEEECCCEEEEEEECCCCCCC
>Mature Secondary Structure
MYMIIKNARVFTEDGSFMQGDVVVKDGRFDSVLERTADTDAANDSESQEIIDASGLIMIP
CEEEEECCEEEECCCCEEECCEEEECCCHHHHHHHHCCCCCCCCCCCHHHHCCCCEEEEC
GLVDIHFHGCKGADMCDGTTEALDVITAYEASVGVTSVCPATMTIQRDELLSVMKNAGDY
CEEEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCCHHCCCCEEEECHHHHHHHHHCCCCC
NYHGGAHLVGINMEGPFISPSKKGAQAAENIMRCDYDYFCELQDAAHGLIKLVDIAPEEP
CCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHCCHHHEEEHHHHHCCEEEEEEECCCCC
GAIDFIDRVRGSVVVSIAHTAADYDTAVEAIEHGASHATHLYNAMPPLHHRNPGVIGAVR
CCCHHHHHCCCEEEEEEEHHHCCHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCEEEEEC
DSKKCHAELICDGVHIHPSVIRATFAMFGAERMILISDSMRATGLEDGEYTLGGQAVTVR
CCCHHCHHHEECCCEECHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCEEECCEEEEEE
GPLATLHDGTIAGSATNLMDCMRFTVRQAGIPLEEAIMCATANPAKEIGIYDEAGSISAG
CCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHEEEECCCCHHHCCCCCCCCCCCCC
KRADFVLLNDDLDIVSVYIDGKEISC
CCCCEEEEECCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]