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The map label for this gene is atpA [H]

Identifier: 238925245

GI number: 238925245

Start: 2777132

End: 2778640

Strand: Reverse

Name: atpA [H]

Synonym: EUBREC_2899

Alternate gene names: 238925245

Gene position: 2778640-2777132 (Counterclockwise)

Preceding gene: 238925246

Following gene: 238925244

Centisome position: 80.55

GC content: 46.52

Gene sequence:

>1509_bases
GTGACCCCTGTGGGCGCAATCAGTGCAACAGACATAATCTCCATTATCCAGAGCGAGATAGAGAATTTCGACTTCGATAC
CGAGAGCCGTGAGACCGGCGAGGTAATCTACGTCGGCGACGGAATCGCCACAATATACGGCATCGACCATGCCATGTACG
GTGAGATCGTAGTATTCGATAATGGAGTAAAAGGAATGGTTCAGGATATCCGTCAGAATGAAATCGGAGTAATCCTTTTC
GGAAGAGACCACGGAATTCATGAAGGAACCAAAGTAGTAAGAACAAAGAAAAAAGCCGGAATCCCTGTAGGCGAAGGCTT
TATCGGCCGAATCATCAATGCTTTAGGTGAGCCTATTGATGGAAAGGGCGATATCAAAGAGGAAGATTACAGACCAATCG
AGAATGAGGCACCGGGTATCGTGGACAGAAAGTCAGTAGATACTCCACTTGAGACAGGAATCCTCTCAATCGATTCAATG
TTCCCAATCGGACGTGGACAGCGAGAGCTTATCATCGGTGACCGTCAGACAGGAAAGACATCAATTGCCACAGATACCAT
CATCAACCAGAAGGGCAAGGATGTTATCTGTATATATGTAGCAATTGGCCAGAAAGCATCAACAGTAGCAAAAATTGTGT
CAACTCTGACAAAACACGGCGCAATGGATTACTCAATCGTGCTTTCATCAACAGCCAGCGATCCTGCATCACTGCAGTAT
ATCGCACCATACGCAGGAACAGCCATGGCAGAGCATTTCATGCATCAGGGCAAGGATGTACTTATCGTATATGATGACCT
TTCAAAGCATGCGGTAGCATACAGAGCACTTTCACTGCTGCTCGAGAGATCACCGGGACGTGAGGCATATCCTGGAGACG
TATTCTATCTCCACTCAAGACTGCTCGAGAGATCAAGCCGTCTGAGCGATGAGCTTGGCGGAGGTTCAATCACAGCACTC
CCAATCATCGAGACACAGGCAGGAGACGTATCAGCATATATCCCTACCAACGTAATATCTATCACAGATGGACAGATATT
CCTAGAGAGCAACCTCTTCAACGCAGGTATGAGACCGGCCGTAAACGTAGGTCTTTCAGTATCCCGAGTTGGTGGAGCTG
CCCAGACAAAGGCCATGAAGAAGGCATCAGGAAGCATCCGTATCGACCTGGCACAGTACAGGGAGATGGAGGTCTTCACA
CAGTTTGCATCAGACCTTGACGATGCCACAAAAGCACAGCTTGCACATGGAAAAGCACTTATGGAGCTTTTAAAACAGCC
GCTTTGTCATCCGCTGTCACTGCATGAGCAGGTAATGACACTTATAATGGCAAACAATGGTGTGTTTGACACAATTGAGA
CAAAAGAGGTCAAGAAATATCAGGGCGATATCCTCTCATACATGGATCTTTCTTATCCGGAAATCGGACAGAAAATCGAA
GAGAACAGAGCCATTGATGAAGAGCTCGTAAATAAAATCATGGATGCAGTAAAAGAGTATAAAGGGTAA

Upstream 100 bases:

>100_bases
AAACACTTTTAGGTGGATATGTGATTAAGACTCTTAATACAGAGTATGACAGAAGCTACGAAGGAAAGCTTCGTGAGCTT
GAAAGAAAATTGACCAGGAG

Downstream 100 bases:

>100_bases
CAGGTAGTATTATGGCAAACACGAAGGAAATACAGGATCGAATAAAAAGTATCAATGATACGCTTAAAATCACAAATGCC
ATGTATATGATTTCTTCTTC

Product: ATP synthase F1, alpha subunit

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 502; Mature: 501

Protein sequence:

>502_residues
MTPVGAISATDIISIIQSEIENFDFDTESRETGEVIYVGDGIATIYGIDHAMYGEIVVFDNGVKGMVQDIRQNEIGVILF
GRDHGIHEGTKVVRTKKKAGIPVGEGFIGRIINALGEPIDGKGDIKEEDYRPIENEAPGIVDRKSVDTPLETGILSIDSM
FPIGRGQRELIIGDRQTGKTSIATDTIINQKGKDVICIYVAIGQKASTVAKIVSTLTKHGAMDYSIVLSSTASDPASLQY
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDELGGGSITAL
PIIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFT
QFASDLDDATKAQLAHGKALMELLKQPLCHPLSLHEQVMTLIMANNGVFDTIETKEVKKYQGDILSYMDLSYPEIGQKIE
ENRAIDEELVNKIMDAVKEYKG

Sequences:

>Translated_502_residues
MTPVGAISATDIISIIQSEIENFDFDTESRETGEVIYVGDGIATIYGIDHAMYGEIVVFDNGVKGMVQDIRQNEIGVILF
GRDHGIHEGTKVVRTKKKAGIPVGEGFIGRIINALGEPIDGKGDIKEEDYRPIENEAPGIVDRKSVDTPLETGILSIDSM
FPIGRGQRELIIGDRQTGKTSIATDTIINQKGKDVICIYVAIGQKASTVAKIVSTLTKHGAMDYSIVLSSTASDPASLQY
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDELGGGSITAL
PIIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFT
QFASDLDDATKAQLAHGKALMELLKQPLCHPLSLHEQVMTLIMANNGVFDTIETKEVKKYQGDILSYMDLSYPEIGQKIE
ENRAIDEELVNKIMDAVKEYKG
>Mature_501_residues
TPVGAISATDIISIIQSEIENFDFDTESRETGEVIYVGDGIATIYGIDHAMYGEIVVFDNGVKGMVQDIRQNEIGVILFG
RDHGIHEGTKVVRTKKKAGIPVGEGFIGRIINALGEPIDGKGDIKEEDYRPIENEAPGIVDRKSVDTPLETGILSIDSMF
PIGRGQRELIIGDRQTGKTSIATDTIINQKGKDVICIYVAIGQKASTVAKIVSTLTKHGAMDYSIVLSSTASDPASLQYI
APYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSRLLERSSRLSDELGGGSITALP
IIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGMRPAVNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQ
FASDLDDATKAQLAHGKALMELLKQPLCHPLSLHEQVMTLIMANNGVFDTIETKEVKKYQGDILSYMDLSYPEIGQKIEE
NRAIDEELVNKIMDAVKEYKG

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=498, Percent_Identity=53.4136546184739, Blast_Score=525, Evalue=1e-149,
Organism=Homo sapiens, GI4757810, Length=498, Percent_Identity=53.4136546184739, Blast_Score=525, Evalue=1e-149,
Organism=Homo sapiens, GI19913428, Length=317, Percent_Identity=29.6529968454259, Blast_Score=122, Evalue=9e-28,
Organism=Homo sapiens, GI19913426, Length=353, Percent_Identity=28.6118980169972, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI32189394, Length=313, Percent_Identity=26.1980830670927, Blast_Score=97, Evalue=5e-20,
Organism=Homo sapiens, GI19913424, Length=255, Percent_Identity=25.4901960784314, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1790172, Length=506, Percent_Identity=50.5928853754941, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1790170, Length=379, Percent_Identity=25.065963060686, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1788251, Length=328, Percent_Identity=26.219512195122, Blast_Score=100, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=501, Percent_Identity=53.4930139720559, Blast_Score=537, Evalue=1e-153,
Organism=Caenorhabditis elegans, GI71988080, Length=501, Percent_Identity=53.4930139720559, Blast_Score=536, Evalue=1e-152,
Organism=Caenorhabditis elegans, GI71988074, Length=501, Percent_Identity=50.2994011976048, Blast_Score=488, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI17510931, Length=379, Percent_Identity=27.4406332453826, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17570191, Length=380, Percent_Identity=28.1578947368421, Blast_Score=121, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI25144756, Length=399, Percent_Identity=24.3107769423559, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=60, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=255, Percent_Identity=25.8823529411765, Blast_Score=70, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=499, Percent_Identity=51.9038076152305, Blast_Score=530, Evalue=1e-151,
Organism=Saccharomyces cerevisiae, GI6319603, Length=348, Percent_Identity=31.3218390804598, Blast_Score=127, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=375, Percent_Identity=24.2666666666667, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24658560, Length=500, Percent_Identity=53.2, Blast_Score=528, Evalue=1e-150,
Organism=Drosophila melanogaster, GI281361666, Length=298, Percent_Identity=29.1946308724832, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24646341, Length=298, Percent_Identity=29.1946308724832, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI17136796, Length=298, Percent_Identity=29.1946308724832, Blast_Score=125, Evalue=9e-29,
Organism=Drosophila melanogaster, GI24638766, Length=313, Percent_Identity=26.8370607028754, Blast_Score=93, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28574560, Length=368, Percent_Identity=23.3695652173913, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=25.4901960784314, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=25.4901960784314, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI20129479, Length=256, Percent_Identity=26.953125, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR018538 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF09378 HAS-barrel [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 54650; Mature: 54519

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPVGAISATDIISIIQSEIENFDFDTESRETGEVIYVGDGIATIYGIDHAMYGEIVVFD
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCHHHCCEEEEEE
NGVKGMVQDIRQNEIGVILFGRDHGIHEGTKVVRTKKKAGIPVGEGFIGRIINALGEPID
CCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
GKGDIKEEDYRPIENEAPGIVDRKSVDTPLETGILSIDSMFPIGRGQRELIIGDRQTGKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEHHCCCCCCCCCCEEEEECCCCCCC
SIATDTIINQKGKDVICIYVAIGQKASTVAKIVSTLTKHGAMDYSIVLSSTASDPASLQY
CHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSR
ECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LLERSSRLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGMRPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCCCCCCCCH
VNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQFASDLDDATKAQLAHGKAL
HHCCEEHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MELLKQPLCHPLSLHEQVMTLIMANNGVFDTIETKEVKKYQGDILSYMDLSYPEIGQKIE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
ENRAIDEELVNKIMDAVKEYKG
HHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TPVGAISATDIISIIQSEIENFDFDTESRETGEVIYVGDGIATIYGIDHAMYGEIVVFD
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCEEEEEECCHHHCCEEEEEE
NGVKGMVQDIRQNEIGVILFGRDHGIHEGTKVVRTKKKAGIPVGEGFIGRIINALGEPID
CCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCC
GKGDIKEEDYRPIENEAPGIVDRKSVDTPLETGILSIDSMFPIGRGQRELIIGDRQTGKT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCEEEHHCCCCCCCCCCEEEEECCCCCCC
SIATDTIINQKGKDVICIYVAIGQKASTVAKIVSTLTKHGAMDYSIVLSSTASDPASLQY
CHHHHHHHCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCEEE
IAPYAGTAMAEHFMHQGKDVLIVYDDLSKHAVAYRALSLLLERSPGREAYPGDVFYLHSR
ECCCHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
LLERSSRLSDELGGGSITALPIIETQAGDVSAYIPTNVISITDGQIFLESNLFNAGMRPA
HHHHHHHHHHHCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEECCCCCCCCCCH
VNVGLSVSRVGGAAQTKAMKKASGSIRIDLAQYREMEVFTQFASDLDDATKAQLAHGKAL
HHCCEEHHHCCCHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
MELLKQPLCHPLSLHEQVMTLIMANNGVFDTIETKEVKKYQGDILSYMDLSYPEIGQKIE
HHHHHHHCCCCHHHHHHHHHHHHCCCCCEECCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
ENRAIDEELVNKIMDAVKEYKG
HHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11997336 [H]