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The map label for this gene is resE [H]

Identifier: 238925078

GI number: 238925078

Start: 2593193

End: 2594440

Strand: Direct

Name: resE [H]

Synonym: EUBREC_2731

Alternate gene names: 238925078

Gene position: 2593193-2594440 (Clockwise)

Preceding gene: 238925077

Following gene: 238925079

Centisome position: 75.17

GC content: 42.63

Gene sequence:

>1248_bases
ATGGAAAGAGGTGTCTATATGAGTTTGTACCAAGATAGACAGATTAAAGGGTTCCTGCTATTTTTGACTTTGTTTGCTCT
GCTGTTTGTAGGTACAGCAACCGTTTTGACTATTTATCAGGTGAACGATGCGGAAGTCCTATGGCTCAAACATGATGAAG
CGGTTTCATCCTCACTTTTGGAACAGGGTGTTCCGAAAGAAGTGGTTGCAGTTGCCTTTACGAACACAGACATCAGTGAC
GATGGTAGGTCATTATTAGCGGCTGCGGGTTTGGGAAAACAGTCAGAAAGCAGTATGCGGCCTTATTTCAATCAATTTCA
GCGTTCCGCTTTCTGCGCCATGCTATGCACTGTGCTATTTTTTCTCTTTGTGCTTGCCATAGGAATATTTATTTTTTTCT
GGAAAAGGAAGCGATTGTATCAACAGGTCGACAGAATATTGCTAAATTACATCAACGGGGATTACTCTTGTCATTTACCG
CAGAATTATGAGGGGGCTATCTACCAAGTGTTTTCTTCGATAGAACAGCTTGCAACTATGCTCCAATCCAAAAATGAAAC
AGAACGTAAAGCAAAAGAGTTTTTGAAAGACACCATATCCGATATATCTCACCAGCTCAAAACGCCTCTGGCAGCCCTCA
CTATGTATCAGGAGATCATTGAAAGTGAGCCAGAAAATGCAGAAACGGTCAAACAGTTTGCGGCGAAGATGGGTATTTCT
CTAAAGCGTATGGAGCAGTTAATCTTATCCATGTTGAAGATAACCCGACTGGATACGGGAAACATCATTTTTGAGAAAAA
AAGTTGCCGTGTGTCCGAGCTGATAGCTCATTCAGTCAATGACCTAACCACCAGGGCTAAAAGCGAAAGCAAGCAGATTC
AGATAGATGGCGATGGTGAACAGCAGCTTATTTGTGACATGGAATGGACAGGTGAAGCGATTGGAAACATTGTAAAAAAT
GCACTGGATCACACGCAAGCTGGCGGTATTGTCCGTATTACATGGGAGCGCACTCCTGCTATGTTTCGGATTTTTATTTC
TGATAATGGTAACGGCATAGTCCCGGAAGATATTTACCATATCTTTAAACGCTTTTATCGCAGCAAACATTCCCTTGATA
CACAAGGAATCGGGCTGGGGCTTCCCCTTGCCAAGTCCATTATTGAGGGTCAAAACGGTGTTATCTCCGTACAAAGTGAA
GTCGGAAAAGGTACGCTGTTTACACTATCTTTCCTTACGGATCTGTAA

Upstream 100 bases:

>100_bases
ATAATACCCTGTCCGTCTATGTACGGCGGCTTCGTGAAAAAGTGGAAACCAATCCGTCCCATCCAGAACACCTTATAACC
ATTCGTGGGTTCGGCTACCA

Downstream 100 bases:

>100_bases
GGTCAAATTCACCTGCTTGTAAGCTGTTTTTGCTATCCTTTTGAGAAAGGAGGTACTGATGACTATGGAAATATTGAAAG
TACAAGATTTATGTAAAACT

Product: putative sensory transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 415; Mature: 415

Protein sequence:

>415_residues
MERGVYMSLYQDRQIKGFLLFLTLFALLFVGTATVLTIYQVNDAEVLWLKHDEAVSSSLLEQGVPKEVVAVAFTNTDISD
DGRSLLAAAGLGKQSESSMRPYFNQFQRSAFCAMLCTVLFFLFVLAIGIFIFFWKRKRLYQQVDRILLNYINGDYSCHLP
QNYEGAIYQVFSSIEQLATMLQSKNETERKAKEFLKDTISDISHQLKTPLAALTMYQEIIESEPENAETVKQFAAKMGIS
LKRMEQLILSMLKITRLDTGNIIFEKKSCRVSELIAHSVNDLTTRAKSESKQIQIDGDGEQQLICDMEWTGEAIGNIVKN
ALDHTQAGGIVRITWERTPAMFRIFISDNGNGIVPEDIYHIFKRFYRSKHSLDTQGIGLGLPLAKSIIEGQNGVISVQSE
VGKGTLFTLSFLTDL

Sequences:

>Translated_415_residues
MERGVYMSLYQDRQIKGFLLFLTLFALLFVGTATVLTIYQVNDAEVLWLKHDEAVSSSLLEQGVPKEVVAVAFTNTDISD
DGRSLLAAAGLGKQSESSMRPYFNQFQRSAFCAMLCTVLFFLFVLAIGIFIFFWKRKRLYQQVDRILLNYINGDYSCHLP
QNYEGAIYQVFSSIEQLATMLQSKNETERKAKEFLKDTISDISHQLKTPLAALTMYQEIIESEPENAETVKQFAAKMGIS
LKRMEQLILSMLKITRLDTGNIIFEKKSCRVSELIAHSVNDLTTRAKSESKQIQIDGDGEQQLICDMEWTGEAIGNIVKN
ALDHTQAGGIVRITWERTPAMFRIFISDNGNGIVPEDIYHIFKRFYRSKHSLDTQGIGLGLPLAKSIIEGQNGVISVQSE
VGKGTLFTLSFLTDL
>Mature_415_residues
MERGVYMSLYQDRQIKGFLLFLTLFALLFVGTATVLTIYQVNDAEVLWLKHDEAVSSSLLEQGVPKEVVAVAFTNTDISD
DGRSLLAAAGLGKQSESSMRPYFNQFQRSAFCAMLCTVLFFLFVLAIGIFIFFWKRKRLYQQVDRILLNYINGDYSCHLP
QNYEGAIYQVFSSIEQLATMLQSKNETERKAKEFLKDTISDISHQLKTPLAALTMYQEIIESEPENAETVKQFAAKMGIS
LKRMEQLILSMLKITRLDTGNIIFEKKSCRVSELIAHSVNDLTTRAKSESKQIQIDGDGEQQLICDMEWTGEAIGNIVKN
ALDHTQAGGIVRITWERTPAMFRIFISDNGNGIVPEDIYHIFKRFYRSKHSLDTQGIGLGLPLAKSIIEGQNGVISVQSE
VGKGTLFTLSFLTDL

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=216, Percent_Identity=28.2407407407407, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1788393, Length=255, Percent_Identity=24.7058823529412, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1786783, Length=305, Percent_Identity=23.9344262295082, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1790861, Length=342, Percent_Identity=22.8070175438596, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790436, Length=231, Percent_Identity=25.974025974026, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788713, Length=274, Percent_Identity=23.3576642335766, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1789403, Length=291, Percent_Identity=21.9931271477663, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789149, Length=352, Percent_Identity=23.5795454545455, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1790346, Length=203, Percent_Identity=23.1527093596059, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI145693157, Length=242, Percent_Identity=25.2066115702479, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=219, Percent_Identity=24.2009132420091, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=26.1224489795918, Blast_Score=62, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 46786; Mature: 46786

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERGVYMSLYQDRQIKGFLLFLTLFALLFVGTATVLTIYQVNDAEVLWLKHDEAVSSSLL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHHHHHHHH
EQGVPKEVVAVAFTNTDISDDGRSLLAAAGLGKQSESSMRPYFNQFQRSAFCAMLCTVLF
HCCCCHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLFVLAIGIFIFFWKRKRLYQQVDRILLNYINGDYSCHLPQNYEGAIYQVFSSIEQLATM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
LQSKNETERKAKEFLKDTISDISHQLKTPLAALTMYQEIIESEPENAETVKQFAAKMGIS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
LKRMEQLILSMLKITRLDTGNIIFEKKSCRVSELIAHSVNDLTTRAKSESKQIQIDGDGE
HHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
QQLICDMEWTGEAIGNIVKNALDHTQAGGIVRITWERTPAMFRIFISDNGNGIVPEDIYH
CEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCCCCHHHHHH
IFKRFYRSKHSLDTQGIGLGLPLAKSIIEGQNGVISVQSEVGKGTLFTLSFLTDL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHCC
>Mature Secondary Structure
MERGVYMSLYQDRQIKGFLLFLTLFALLFVGTATVLTIYQVNDAEVLWLKHDEAVSSSLL
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEECCCEEEEEECHHHHHHHHH
EQGVPKEVVAVAFTNTDISDDGRSLLAAAGLGKQSESSMRPYFNQFQRSAFCAMLCTVLF
HCCCCHHHEEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
FLFVLAIGIFIFFWKRKRLYQQVDRILLNYINGDYSCHLPQNYEGAIYQVFSSIEQLATM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHH
LQSKNETERKAKEFLKDTISDISHQLKTPLAALTMYQEIIESEPENAETVKQFAAKMGIS
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
LKRMEQLILSMLKITRLDTGNIIFEKKSCRVSELIAHSVNDLTTRAKSESKQIQIDGDGE
HHHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
QQLICDMEWTGEAIGNIVKNALDHTQAGGIVRITWERTPAMFRIFISDNGNGIVPEDIYH
CEEEEECCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCEEEEEEEECCCCCCCHHHHHH
IFKRFYRSKHSLDTQGIGLGLPLAKSIIEGQNGVISVQSEVGKGTLFTLSFLTDL
HHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCEEEHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]