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The map label for this gene is basR [C]

Identifier: 238925077

GI number: 238925077

Start: 2592516

End: 2593214

Strand: Direct

Name: basR [C]

Synonym: EUBREC_2730

Alternate gene names: 238925077

Gene position: 2592516-2593214 (Clockwise)

Preceding gene: 238925076

Following gene: 238925078

Centisome position: 75.15

GC content: 43.06

Gene sequence:

>699_bases
ATGAATAGAATATTGCTATTGGAGGATGATGTCAGTCTAATAGATGGCTTGGTCTACTCTTTGAAAAAGAATGAATTTGA
TGTTGAAGTTGCCCGTACAGTATGTGAAGCAAAACAATACTTATCCGAACTCGACCGATACGATTTATTGATTTTGGATG
TTACTCTGCCAGATGGAACAGGATTTGACGTATGCGAAAGAGTAAGAAAAGAAAATCAGCAGATACCGATTATATTCCTG
ACTGCATCGGATGAAGAAGTCAGCATAATTCGTGGATTAGATAGCGGTGGGGACGATTATATCACCAAGCCTTTCAAACT
GGGGGAATTGTGTTCCCGCATCCGGGCGCTGTTGCGTCGGGCCGGAGTTTCCAAAAGCGAAAAAAACACTTCTATGGAAT
GTGGCGACATTACCATTGATCTGTTGGGTAGCCGTGCAACCTTAAAGGGAAAAGCATTGGATTTGACAAGCGCCGAATAT
CGTTTGCTTTGTCTGCTGGTAAGAAACGCAAATCGCGTTGTGACAAGGGACATCATTCTAAATGAGCTGTGGGATGATAC
AGGAAATTTTGTTGATGATAATACCCTGTCCGTCTATGTACGGCGGCTTCGTGAAAAAGTGGAAACCAATCCGTCCCATC
CAGAACACCTTATAACCATTCGTGGGTTCGGCTACCAATGGAAAGAGGTGTCTATATGA

Upstream 100 bases:

>100_bases
CGTATTCCCGGCGCTGTGAAGATGGCTACAATCTGGTTGATCCCGAAAGACGCGGAGAAACCTGTGGATATGAGGACAAA
ACAAGGAAAGGAATTAAAAC

Downstream 100 bases:

>100_bases
GTTTGTACCAAGATAGACAGATTAAAGGGTTCCTGCTATTTTTGACTTTGTTTGCTCTGCTGTTTGTAGGTACAGCAACC
GTTTTGACTATTTATCAGGT

Product: two component transcriptional regulator, winged helix family

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNRILLLEDDVSLIDGLVYSLKKNEFDVEVARTVCEAKQYLSELDRYDLLILDVTLPDGTGFDVCERVRKENQQIPIIFL
TASDEEVSIIRGLDSGGDDYITKPFKLGELCSRIRALLRRAGVSKSEKNTSMECGDITIDLLGSRATLKGKALDLTSAEY
RLLCLLVRNANRVVTRDIILNELWDDTGNFVDDNTLSVYVRRLREKVETNPSHPEHLITIRGFGYQWKEVSI

Sequences:

>Translated_232_residues
MNRILLLEDDVSLIDGLVYSLKKNEFDVEVARTVCEAKQYLSELDRYDLLILDVTLPDGTGFDVCERVRKENQQIPIIFL
TASDEEVSIIRGLDSGGDDYITKPFKLGELCSRIRALLRRAGVSKSEKNTSMECGDITIDLLGSRATLKGKALDLTSAEY
RLLCLLVRNANRVVTRDIILNELWDDTGNFVDDNTLSVYVRRLREKVETNPSHPEHLITIRGFGYQWKEVSI
>Mature_232_residues
MNRILLLEDDVSLIDGLVYSLKKNEFDVEVARTVCEAKQYLSELDRYDLLILDVTLPDGTGFDVCERVRKENQQIPIIFL
TASDEEVSIIRGLDSGGDDYITKPFKLGELCSRIRALLRRAGVSKSEKNTSMECGDITIDLLGSRATLKGKALDLTSAEY
RLLCLLVRNANRVVTRDIILNELWDDTGNFVDDNTLSVYVRRLREKVETNPSHPEHLITIRGFGYQWKEVSI

Specific function: Member Of The Two-Component Regulatory System Bass/Basr. Polymyxin Resistance May Be Mediated By An Interaction Between Basr (Pmra) Or A Basr-Regulated Gene Product And Pmrd (By Similarity). [C]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=36.8888888888889, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786599, Length=232, Percent_Identity=33.1896551724138, Blast_Score=134, Evalue=7e-33,
Organism=Escherichia coli, GI1786784, Length=224, Percent_Identity=35.2678571428571, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=35.6521739130435, Blast_Score=131, Evalue=4e-32,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=36.2445414847162, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=35.2173913043478, Blast_Score=125, Evalue=2e-30,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=33.7719298245614, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082012, Length=232, Percent_Identity=35.7758620689655, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1788394, Length=226, Percent_Identity=32.3008849557522, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=31.25, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=32.9059829059829, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=34.6320346320346, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787229, Length=182, Percent_Identity=34.0659340659341, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.8135593220339, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26343; Mature: 26343

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRILLLEDDVSLIDGLVYSLKKNEFDVEVARTVCEAKQYLSELDRYDLLILDVTLPDGT
CCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GFDVCERVRKENQQIPIIFLTASDEEVSIIRGLDSGGDDYITKPFKLGELCSRIRALLRR
CHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGVSKSEKNTSMECGDITIDLLGSRATLKGKALDLTSAEYRLLCLLVRNANRVVTRDIIL
CCCCCCCCCCCCCCCCEEEEEECCCCEECCCEEECCCHHHHEEEEEECCCCCCHHHHHHH
NELWDDTGNFVDDNTLSVYVRRLREKVETNPSHPEHLITIRGFGYQWKEVSI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECC
>Mature Secondary Structure
MNRILLLEDDVSLIDGLVYSLKKNEFDVEVARTVCEAKQYLSELDRYDLLILDVTLPDGT
CCCEEEEECCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCC
GFDVCERVRKENQQIPIIFLTASDEEVSIIRGLDSGGDDYITKPFKLGELCSRIRALLRR
CHHHHHHHHHCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHH
AGVSKSEKNTSMECGDITIDLLGSRATLKGKALDLTSAEYRLLCLLVRNANRVVTRDIIL
CCCCCCCCCCCCCCCCEEEEEECCCCEECCCEEECCCHHHHEEEEEECCCCCCHHHHHHH
NELWDDTGNFVDDNTLSVYVRRLREKVETNPSHPEHLITIRGFGYQWKEVSI
HHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1554697 [H]