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The map label for this gene is gph [C]

Identifier: 238921467

GI number: 238921467

Start: 3506309

End: 3506995

Strand: Reverse

Name: gph [C]

Synonym: NT01EI_3619

Alternate gene names: 238921467

Gene position: 3506995-3506309 (Counterclockwise)

Preceding gene: 238921468

Following gene: 238921466

Centisome position: 91.99

GC content: 63.76

Gene sequence:

>687_bases
ATGAATAAAGGTATTCCGGTACAGGCACTGGCCTTTGATTTGGACGGCACGCTGGTGGATAGCGCGTCGGGTCTGGCGGC
GGCTACGGACGCGGCGATGCTGGCGCTGGACTACCCGGCGCCGGGCGTGGAGCGGGTGAAGCTGTGGCTGGGAAACGGCG
CAGATGTTCTGATGCAGCGCGCCTTGAGCTGGGCGGGTGCCCCGCAGGATGCCGCACTGTGTCAGCGTGCGCGGCGCGCA
TTTGACGCGCATTACGCCGAGAGCGCCAATCAGGGGTGTCAGTTGTTTCCCGGCGTCCGGGAGACGCTGGGGGTACTGGC
GGCCAAGGGATTTCCGCTGGCGGTTATCACCAATAAGCCCTCGCCCTTTGTCCGCCCGATGCTGGAGAGTCTGGGGATCG
ATGCACTCTTCGGTCAGGTGATCGGCGGCGATGATGTCGCTAAGCGTAAGCCCCATCCGGCCCCGCTCTATCTGGTGCTG
TCCCGTCTGGGGCTGCGGGCCGATGAGATGCTGTTTGTCGGTGACTCGCGCAATGATATCCAAGCTGGCCAGTCGGCCGG
CTGTCCTACCGTCGGCTTGACCTACGGTTATAACTATGGCGAACCTATCGCTGCCAGCGAGCCCTGCTGCGTGCTGGATG
ACTTTGCCGGCCTGCTGCCCTTGGTAGGGTTGGCGCCGCTGAACTGA

Upstream 100 bases:

>100_bases
GCTGGCGCCGATATGTTTGTTGCCGGCTCGGCTATTTTCGGTCACGCCGACTATGCGGCGGTGATCACGGATATGCGTCA
TGAGATTGCGCAGGCCTGCC

Downstream 100 bases:

>100_bases
ATTGATAAGGACAGGAATGTGACCATGAGTAAGCCCATTGTTTTCAGCGGTGCGCAGCCGTCTGGTGAACTCACCATCGG
TAACTATATGGGCGCGCTGC

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP; PGPase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MNKGIPVQALAFDLDGTLVDSASGLAAATDAAMLALDYPAPGVERVKLWLGNGADVLMQRALSWAGAPQDAALCQRARRA
FDAHYAESANQGCQLFPGVRETLGVLAAKGFPLAVITNKPSPFVRPMLESLGIDALFGQVIGGDDVAKRKPHPAPLYLVL
SRLGLRADEMLFVGDSRNDIQAGQSAGCPTVGLTYGYNYGEPIAASEPCCVLDDFAGLLPLVGLAPLN

Sequences:

>Translated_228_residues
MNKGIPVQALAFDLDGTLVDSASGLAAATDAAMLALDYPAPGVERVKLWLGNGADVLMQRALSWAGAPQDAALCQRARRA
FDAHYAESANQGCQLFPGVRETLGVLAAKGFPLAVITNKPSPFVRPMLESLGIDALFGQVIGGDDVAKRKPHPAPLYLVL
SRLGLRADEMLFVGDSRNDIQAGQSAGCPTVGLTYGYNYGEPIAASEPCCVLDDFAGLLPLVGLAPLN
>Mature_228_residues
MNKGIPVQALAFDLDGTLVDSASGLAAATDAAMLALDYPAPGVERVKLWLGNGADVLMQRALSWAGAPQDAALCQRARRA
FDAHYAESANQGCQLFPGVRETLGVLAAKGFPLAVITNKPSPFVRPMLESLGIDALFGQVIGGDDVAKRKPHPAPLYLVL
SRLGLRADEMLFVGDSRNDIQAGQSAGCPTVGLTYGYNYGEPIAASEPCCVLDDFAGLLPLVGLAPLN

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

Organism=Escherichia coli, GI1789787, Length=243, Percent_Identity=53.9094650205761, Blast_Score=251, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 23865; Mature: 23865

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKGIPVQALAFDLDGTLVDSASGLAAATDAAMLALDYPAPGVERVKLWLGNGADVLMQR
CCCCCCEEEEEEECCCCEECCCCCCHHHHCCEEEEEECCCCCCEEEEEEECCCHHHHHHH
ALSWAGAPQDAALCQRARRAFDAHYAESANQGCQLFPGVRETLGVLAAKGFPLAVITNKP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCCEEEEECCC
SPFVRPMLESLGIDALFGQVIGGDDVAKRKPHPAPLYLVLSRLGLRADEMLFVGDSRNDI
CHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHH
QAGQSAGCPTVGLTYGYNYGEPIAASEPCCVLDDFAGLLPLVGLAPLN
HCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKGIPVQALAFDLDGTLVDSASGLAAATDAAMLALDYPAPGVERVKLWLGNGADVLMQR
CCCCCCEEEEEEECCCCEECCCCCCHHHHCCEEEEEECCCCCCEEEEEEECCCHHHHHHH
ALSWAGAPQDAALCQRARRAFDAHYAESANQGCQLFPGVRETLGVLAAKGFPLAVITNKP
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHHHCCCCCEEEEECCC
SPFVRPMLESLGIDALFGQVIGGDDVAKRKPHPAPLYLVLSRLGLRADEMLFVGDSRNDI
CHHHHHHHHHCCHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCCCEEEECCCCCHH
QAGQSAGCPTVGLTYGYNYGEPIAASEPCCVLDDFAGLLPLVGLAPLN
HCCCCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA