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The map label for this gene is tldD [H]

Identifier: 238921340

GI number: 238921340

Start: 3378581

End: 3380026

Strand: Reverse

Name: tldD [H]

Synonym: NT01EI_3484

Alternate gene names: 238921340

Gene position: 3380026-3378581 (Counterclockwise)

Preceding gene: 238921341

Following gene: 238921338

Centisome position: 88.66

GC content: 64.52

Gene sequence:

>1446_bases
ATGAGTCTGACGTTTGTCAGTGAGCAGTTACTGGCTGCCAACAATCTGAATCATCAGGATTTATATAATGTCTTGGGGCA
GTTGAATGCACGGCGCCTGGACTATGCCGATCTCTATTTCCAGTCCAGCGTACACGAATCCTGGGTATTGGAAGATCGCA
TCATTAAAGAGGGCTCTTACCATATCGATCAGGGGGTGGGGGTGCGGGCCATCCACGGTGAAAAGACCGGGTTCGCCTAT
GCCGATCAGATAACCCTGCAGGCGCTGACCCAGAGCGCCCACGCCGCGCGCAGCATCGTGCGCGAGCAGGGCGATGGGCG
ATCGCACACCCTGGGAGGGCTCAAGGCGGTCTCCCGCTACGGCACGCACTCCCCGCTCGATAGCCTGCCACGCGAGGAGA
AGATCGCGTTGCTGGCGCAGGTCGATCGGGTGGCGCGGGCGGCCGATGCCCGGGTTCAGGAGGTGAATGCCAGCCTGACC
GGGGTGTATGAGCTGGTGCTGGTGGCCGCCAGCGACGGTACGCTGGCGGCGGACGTACGGCCGTTGGTGCGCCTCTCCGT
CAGCGTGCTGGTGGAGCAGGATGGCCGACGCGAGCGCGGCAGCTGCGGTGGCGGCGGCCGCTTTGGCTATGATTGCTTCC
TGACCCCCCACGACGGCGAGGTGTGTGCCGATGCCTATGCGCGCGAGGCGGTACGCATGGCGCTGGTCAACCTGCACGCC
AAGGCGGCACCGGCCGGTACCATGCCGGTGGTACTCGGCGCCGGCTGGCCGGGTGTGTTGCTGCACGAGGCGGTCGGCCA
CGGGCTGGAGGGGGACTTTAACCGGCGCGGCACCTCTGTGTTCAGCGGTCAGCTGGGCCAGCAGGTGGCCTCGCCGCTGT
GTACCGTGGTGGACGATGGTACGCTGGAGGGGCGGCGCGGTTCGCTGGCGGTGGATGACGAAGGGGTACCCGGCCAGTAC
AACGTACTGATTGAGAACGGGGTGCTGCGTGGCTATATGCAGGATAAGCTCAACGCCCGCCTGATGGGGATGGCGCCGAC
CGGCAACGGCCGCCGCGAATCCTATGCCCACCTGCCGATGCCGCGGATGACCAACACCTATATGCTGGCCGGGGAGAGCA
CGCCGCAGGCGATTATCGAGAGCGTGGAGTATGGGTTGTATGCCCCTAACTTCGCCGGTGGTCAGGTCGATATCACCTCA
GGTAAGTTTGTCTTCTCCACCTCTGAAGCCTATCTGATCGAGAAGGGACGGATCACCCATCCGGTGAAGGGGGCGACCCT
GATCGGCTCCGGCATTGAGGCGATGCAGCAGATCTCGATGGTGGGCAACGATCTGGCGCTGGATAAGGGGGTCGGGGTCT
GCGGCAAAGAGGGGCAGAGCGTGCCGGTCGGCGTCGGCCAGCCGACGCTGAGGCTGGATGCGATGACCGTCGGCGGCACC
GCCTGA

Upstream 100 bases:

>100_bases
AATACCAACTCACTGAGCGTGCTGCGCGATCAGATGCCACTGGCACAGCACAACCGATTCCAGCCTGAGCTGATCCATCT
TCACCAAGGGTAAATACACC

Downstream 100 bases:

>100_bases
GTTCGGCGCGATTCGCCACGGTATCTCCCGCGGGCCGGCCTTTGCCGGCCCGCGCTATTTCTCCTGGCGGGTATCGCGGA
AGGTATCCGCCATCTGGGCA

Product: protease TldD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MSLTFVSEQLLAANNLNHQDLYNVLGQLNARRLDYADLYFQSSVHESWVLEDRIIKEGSYHIDQGVGVRAIHGEKTGFAY
ADQITLQALTQSAHAARSIVREQGDGRSHTLGGLKAVSRYGTHSPLDSLPREEKIALLAQVDRVARAADARVQEVNASLT
GVYELVLVAASDGTLAADVRPLVRLSVSVLVEQDGRRERGSCGGGGRFGYDCFLTPHDGEVCADAYAREAVRMALVNLHA
KAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQLGQQVASPLCTVVDDGTLEGRRGSLAVDDEGVPGQY
NVLIENGVLRGYMQDKLNARLMGMAPTGNGRRESYAHLPMPRMTNTYMLAGESTPQAIIESVEYGLYAPNFAGGQVDITS
GKFVFSTSEAYLIEKGRITHPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSVPVGVGQPTLRLDAMTVGGT
A

Sequences:

>Translated_481_residues
MSLTFVSEQLLAANNLNHQDLYNVLGQLNARRLDYADLYFQSSVHESWVLEDRIIKEGSYHIDQGVGVRAIHGEKTGFAY
ADQITLQALTQSAHAARSIVREQGDGRSHTLGGLKAVSRYGTHSPLDSLPREEKIALLAQVDRVARAADARVQEVNASLT
GVYELVLVAASDGTLAADVRPLVRLSVSVLVEQDGRRERGSCGGGGRFGYDCFLTPHDGEVCADAYAREAVRMALVNLHA
KAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQLGQQVASPLCTVVDDGTLEGRRGSLAVDDEGVPGQY
NVLIENGVLRGYMQDKLNARLMGMAPTGNGRRESYAHLPMPRMTNTYMLAGESTPQAIIESVEYGLYAPNFAGGQVDITS
GKFVFSTSEAYLIEKGRITHPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSVPVGVGQPTLRLDAMTVGGT
A
>Mature_480_residues
SLTFVSEQLLAANNLNHQDLYNVLGQLNARRLDYADLYFQSSVHESWVLEDRIIKEGSYHIDQGVGVRAIHGEKTGFAYA
DQITLQALTQSAHAARSIVREQGDGRSHTLGGLKAVSRYGTHSPLDSLPREEKIALLAQVDRVARAADARVQEVNASLTG
VYELVLVAASDGTLAADVRPLVRLSVSVLVEQDGRRERGSCGGGGRFGYDCFLTPHDGEVCADAYAREAVRMALVNLHAK
AAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQLGQQVASPLCTVVDDGTLEGRRGSLAVDDEGVPGQYN
VLIENGVLRGYMQDKLNARLMGMAPTGNGRRESYAHLPMPRMTNTYMLAGESTPQAIIESVEYGLYAPNFAGGQVDITSG
KFVFSTSEAYLIEKGRITHPVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSVPVGVGQPTLRLDAMTVGGTA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=481, Percent_Identity=80.4573804573805, Blast_Score=767, Evalue=0.0,
Organism=Escherichia coli, GI1790682, Length=404, Percent_Identity=22.5247524752475, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51190; Mature: 51058

Theoretical pI: Translated: 5.91; Mature: 5.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLTFVSEQLLAANNLNHQDLYNVLGQLNARRLDYADLYFQSSVHESWVLEDRIIKEGSY
CCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCC
HIDQGVGVRAIHGEKTGFAYADQITLQALTQSAHAARSIVREQGDGRSHTLGGLKAVSRY
EECCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GTHSPLDSLPREEKIALLAQVDRVARAADARVQEVNASLTGVYELVLVAASDGTLAADVR
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEECCCCEEHHHH
PLVRLSVSVLVEQDGRRERGSCGGGGRFGYDCFLTPHDGEVCADAYAREAVRMALVNLHA
HHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQLGQQVASPLCTVVDDG
CCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCC
TLEGRRGSLAVDDEGVPGQYNVLIENGVLRGYMQDKLNARLMGMAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLAGESTPQAIIESVEYGLYAPNFAGGQVDITSGKFVFSTSEAYLIEKGRITH
CCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSVPVGVGQPTLRLDAMTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
A
C
>Mature Secondary Structure 
SLTFVSEQLLAANNLNHQDLYNVLGQLNARRLDYADLYFQSSVHESWVLEDRIIKEGSY
CCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCC
HIDQGVGVRAIHGEKTGFAYADQITLQALTQSAHAARSIVREQGDGRSHTLGGLKAVSRY
EECCCCCEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHC
GTHSPLDSLPREEKIALLAQVDRVARAADARVQEVNASLTGVYELVLVAASDGTLAADVR
CCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEEEEECCCCEEHHHH
PLVRLSVSVLVEQDGRRERGSCGGGGRFGYDCFLTPHDGEVCADAYAREAVRMALVNLHA
HHHHHHHHHEEECCCCCCCCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
KAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRRGTSVFSGQLGQQVASPLCTVVDDG
CCCCCCCCCEEEECCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEECCC
TLEGRRGSLAVDDEGVPGQYNVLIENGVLRGYMQDKLNARLMGMAPTGNGRRESYAHLPM
CCCCCCCCEEECCCCCCCEEEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCCEECCCC
PRMTNTYMLAGESTPQAIIESVEYGLYAPNFAGGQVDITSGKFVFSTSEAYLIEKGRITH
CCCCCEEEEECCCCHHHHHHHHHHCCCCCCCCCCEEEECCCEEEEECCCEEEEECCCCCC
PVKGATLIGSGIEAMQQISMVGNDLALDKGVGVCGKEGQSVPVGVGQPTLRLDAMTVGGT
CCCCCEEEHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
A
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]