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The map label for this gene is yqfA [H]

Identifier: 238921207

GI number: 238921207

Start: 3233456

End: 3234109

Strand: Direct

Name: yqfA [H]

Synonym: NT01EI_3349

Alternate gene names: 238921207

Gene position: 3233456-3234109 (Clockwise)

Preceding gene: 238921204

Following gene: 238921216

Centisome position: 84.82

GC content: 57.03

Gene sequence:

>654_bases
ATGATGACAACCGCTTCCCCGCTGCAACCGGGATACTCTCTGACCGAAGAGGTCGCCAATAGCATCAGCCACGGCATCGG
TTTTATTCTGGGGATCGTCGGGCTGGTCCTGCTGCTGCTACAGGCTATCGGCAACGGTGCCAGCGCGATGGCCATTACCA
GCTATAGCCTGTACGGCGGCAGTATGGTACTGCTGTTTCTGGCCTCAACCCTCTACCACGCCATCCCTAACCGGGCAGCC
AAGCGCTGGCTTAAAGTCTTTGACCACTGCGCCATCTATCTGCTGATCGCCGGAACCTATACCCCCTTTTTACTGGTTGG
GCTGGATTCACCGCTGGCGCGCGGACTGATGGCGGTGATTTGGATACTGGCTCTGCTGGGGATCCTGTTTAAGCTGGCCT
TCGCCCACCGCTTTAAGATCGTCTCGTTGATCACCTATCTAACCATGGGCTGGCTCTCGCTGATCGTTATCTATCAGCTG
GCGATGCGCCTCTCCGGCGCGGGGATCGCGCTGCTGGCGTTGGGGGGGATCGTGTATACCCTGGGGGTTATCTTCTACGT
CTGCAAGCGTATTCCCTACAACCACGCTATCTGGCATACCTTTGTCCTCGGCGGCAGCGCCTGTCACTTCTTCGCTATCT
ATCTATACCTCTAA

Upstream 100 bases:

>100_bases
GGCCATTCCTTCACTGGTGGAATGACCTCGCGTTGGGAGACGTTTCCTCCGGCTTACTTAAGCCCGTCGCGGGTCAGGCT
TCCCTGCGTGAGATCATACG

Downstream 100 bases:

>100_bases
GTAAAACGGCGGCAGGGGAGAGTCCCCTGCCGCCGTCATGCTCACTCTACCCACATCATTCGCCTTCGGTGACTGCACTG
TCGTCACGGCGCTGGCCGAT

Product: channel forming cytolysin

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MMTTASPLQPGYSLTEEVANSISHGIGFILGIVGLVLLLLQAIGNGASAMAITSYSLYGGSMVLLFLASTLYHAIPNRAA
KRWLKVFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMAVIWILALLGILFKLAFAHRFKIVSLITYLTMGWLSLIVIYQL
AMRLSGAGIALLALGGIVYTLGVIFYVCKRIPYNHAIWHTFVLGGSACHFFAIYLYL

Sequences:

>Translated_217_residues
MMTTASPLQPGYSLTEEVANSISHGIGFILGIVGLVLLLLQAIGNGASAMAITSYSLYGGSMVLLFLASTLYHAIPNRAA
KRWLKVFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMAVIWILALLGILFKLAFAHRFKIVSLITYLTMGWLSLIVIYQL
AMRLSGAGIALLALGGIVYTLGVIFYVCKRIPYNHAIWHTFVLGGSACHFFAIYLYL
>Mature_217_residues
MMTTASPLQPGYSLTEEVANSISHGIGFILGIVGLVLLLLQAIGNGASAMAITSYSLYGGSMVLLFLASTLYHAIPNRAA
KRWLKVFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMAVIWILALLGILFKLAFAHRFKIVSLITYLTMGWLSLIVIYQL
AMRLSGAGIALLALGGIVYTLGVIFYVCKRIPYNHAIWHTFVLGGSACHFFAIYLYL

Specific function: Unknown

COG id: COG1272

COG function: function code R; Predicted membrane protein, hemolysin III homolog

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0073 (Hly-III) family [H]

Homologues:

Organism=Homo sapiens, GI154759275, Length=224, Percent_Identity=32.5892857142857, Blast_Score=108, Evalue=3e-24,
Organism=Homo sapiens, GI52630445, Length=226, Percent_Identity=32.3008849557522, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI154759277, Length=248, Percent_Identity=29.4354838709677, Blast_Score=95, Evalue=4e-20,
Organism=Escherichia coli, GI1789266, Length=216, Percent_Identity=76.3888888888889, Blast_Score=337, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI71996356, Length=217, Percent_Identity=34.1013824884793, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI24640324, Length=229, Percent_Identity=31.4410480349345, Blast_Score=92, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004254
- InterPro:   IPR005744 [H]

Pfam domain/function: PF03006 HlyIII [H]

EC number: NA

Molecular weight: Translated: 23608; Mature: 23608

Theoretical pI: Translated: 9.58; Mature: 9.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTTASPLQPGYSLTEEVANSISHGIGFILGIVGLVLLLLQAIGNGASAMAITSYSLYGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SMVLLFLASTLYHAIPNRAAKRWLKVFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMAVI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHH
WILALLGILFKLAFAHRFKIVSLITYLTMGWLSLIVIYQLAMRLSGAGIALLALGGIVYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGVIFYVCKRIPYNHAIWHTFVLGGSACHFFAIYLYL
HHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHC
>Mature Secondary Structure
MMTTASPLQPGYSLTEEVANSISHGIGFILGIVGLVLLLLQAIGNGASAMAITSYSLYGG
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
SMVLLFLASTLYHAIPNRAAKRWLKVFDHCAIYLLIAGTYTPFLLVGLDSPLARGLMAVI
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCHHHEEEEECCCHHHHHHHHHH
WILALLGILFKLAFAHRFKIVSLITYLTMGWLSLIVIYQLAMRLSGAGIALLALGGIVYT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LGVIFYVCKRIPYNHAIWHTFVLGGSACHFFAIYLYL
HHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]