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The map label for this gene is pheA [H]

Identifier: 238921076

GI number: 238921076

Start: 3089423

End: 3090586

Strand: Direct

Name: pheA [H]

Synonym: NT01EI_3211

Alternate gene names: 238921076

Gene position: 3089423-3090586 (Clockwise)

Preceding gene: 238921075

Following gene: 238921079

Centisome position: 81.04

GC content: 58.08

Gene sequence:

>1164_bases
ATGAGTACACTCAATCCATTATTGACGCTGCGCGAGCAGATTAGCGCCGTCGACAGCCAGTTGCTGGCTCTACTGGGCGA
ACGCCGCCGCCTGGCCGAGCAGGTCGCCCGAACCAAACAGGCACTGCATCATCCAGTTCGAGACCGGGCCAGAGAGCGTG
ATTTGCTGCTCAGCCTGATTGAACAGGGAAAACCGCTGCAGCTTGATGCACATTTTATTACTCGCCTGTTTCAACTGATT
ATCGAAGACTCGGTGCTAACCCAACAGGCGTTGCTACAGCAGTCGTACTTGGCCACCGCCGCCGCACGCATCGCCTTTCT
CGGCCCTAAAGGCTCCTATTCCCATCTGGCCGCCCGCCACTATGCCGCGCGCTATTTTGATCAAATGCTAGAGTGCGGCT
GCCAGCGTTTTCAAGACGTCTTCGCCCAGGTAGAAAACGGCCAGGCCGACTATGCCGTACTACCGATAGAAAACACCTCA
TCTGGCGCCATTAACGACGTCTACGATTTGTTGCAGCATACCAGCCTATCTATTGTCGGCGAGCTAACGCTGCCCATCGA
GCACTGCCTGCTGATCGCCGGTGAGGGCGATATCAACACGCTGACCACTGTCTACAGCCACCCTCAGCCGTTTCAGCAAT
GCAGCCAGTTCCTCAGCCGCTACCCACAGTGGCATATCGAATACTGTGAAAGCACTGCCGCCGCGATGGAGAAGGTCGCC
GCACTGTGCTCCCCCCAGGCAGCGGCCCTGGGCAGCGCCGACGGCGGCAATCTGTATGGTCTGCAGCCACTGGCGCACGA
TCTGGCCAACCAGGCCCAGAACATGACCCGATTCATCGTCCTGGCGCGCAAAGCGATCGAGGTCAATCCCCAAATCGCCG
CCAAAACCACGCTGATCATGGCGACGGGCCAACAACCCGGGGCGCTGGTCGATGCGCTGCTGGCCTTCCGCGAGCAACAT
ATTGTCATCACCAAGCTGGAGTCTCGGCCGATAAACGGCAATCCGTGGGAGGAGATGTTCTATCTGGATGTACAGGCTAA
TCTGAACGATCCTGCCATGCTGCGAGCACTGCATGACCTGCAGGCGCTCACCCGATCACAGAAAATCTTGGGCTGCTACC
CAAGTGAAAACGTGGTGCCGGTCGCACCGACCGGGCAATCATAA

Upstream 100 bases:

>100_bases
CGCTCTACGCTAGGAAAGCAGCGAAAGAATGACGTAAGTCCTCCCTAGGGAGGCTTTTTTATGCGTACCACCACTGCACC
AAGCTGATTAAGGGCCCCTG

Downstream 100 bases:

>100_bases
TCCTTATGCTGCCGCGACATCAGCCGCGGCGATCGTGCGCCTGGCTCAGCAACGCCCGGCTCTCATCCTGAAAACGCTGC
GCATCTTCGCCGAACCAGCG

Product: bifunctional chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSTLNPLLTLREQISAVDSQLLALLGERRRLAEQVARTKQALHHPVRDRARERDLLLSLIEQGKPLQLDAHFITRLFQLI
IEDSVLTQQALLQQSYLATAAARIAFLGPKGSYSHLAARHYAARYFDQMLECGCQRFQDVFAQVENGQADYAVLPIENTS
SGAINDVYDLLQHTSLSIVGELTLPIEHCLLIAGEGDINTLTTVYSHPQPFQQCSQFLSRYPQWHIEYCESTAAAMEKVA
ALCSPQAAALGSADGGNLYGLQPLAHDLANQAQNMTRFIVLARKAIEVNPQIAAKTTLIMATGQQPGALVDALLAFREQH
IVITKLESRPINGNPWEEMFYLDVQANLNDPAMLRALHDLQALTRSQKILGCYPSENVVPVAPTGQS

Sequences:

>Translated_387_residues
MSTLNPLLTLREQISAVDSQLLALLGERRRLAEQVARTKQALHHPVRDRARERDLLLSLIEQGKPLQLDAHFITRLFQLI
IEDSVLTQQALLQQSYLATAAARIAFLGPKGSYSHLAARHYAARYFDQMLECGCQRFQDVFAQVENGQADYAVLPIENTS
SGAINDVYDLLQHTSLSIVGELTLPIEHCLLIAGEGDINTLTTVYSHPQPFQQCSQFLSRYPQWHIEYCESTAAAMEKVA
ALCSPQAAALGSADGGNLYGLQPLAHDLANQAQNMTRFIVLARKAIEVNPQIAAKTTLIMATGQQPGALVDALLAFREQH
IVITKLESRPINGNPWEEMFYLDVQANLNDPAMLRALHDLQALTRSQKILGCYPSENVVPVAPTGQS
>Mature_386_residues
STLNPLLTLREQISAVDSQLLALLGERRRLAEQVARTKQALHHPVRDRARERDLLLSLIEQGKPLQLDAHFITRLFQLII
EDSVLTQQALLQQSYLATAAARIAFLGPKGSYSHLAARHYAARYFDQMLECGCQRFQDVFAQVENGQADYAVLPIENTSS
GAINDVYDLLQHTSLSIVGELTLPIEHCLLIAGEGDINTLTTVYSHPQPFQQCSQFLSRYPQWHIEYCESTAAAMEKVAA
LCSPQAAALGSADGGNLYGLQPLAHDLANQAQNMTRFIVLARKAIEVNPQIAAKTTLIMATGQQPGALVDALLAFREQHI
VITKLESRPINGNPWEEMFYLDVQANLNDPAMLRALHDLQALTRSQKILGCYPSENVVPVAPTGQS

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=386, Percent_Identity=69.6891191709845, Blast_Score=552, Evalue=1e-158,
Organism=Saccharomyces cerevisiae, GI6324013, Length=336, Percent_Identity=24.4047619047619, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 42759; Mature: 42628

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLNPLLTLREQISAVDSQLLALLGERRRLAEQVARTKQALHHPVRDRARERDLLLSLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EQGKPLQLDAHFITRLFQLIIEDSVLTQQALLQQSYLATAAARIAFLGPKGSYSHLAARH
HCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
YAARYFDQMLECGCQRFQDVFAQVENGQADYAVLPIENTSSGAINDVYDLLQHTSLSIVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHE
ELTLPIEHCLLIAGEGDINTLTTVYSHPQPFQQCSQFLSRYPQWHIEYCESTAAAMEKVA
EEHCCHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ALCSPQAAALGSADGGNLYGLQPLAHDLANQAQNMTRFIVLARKAIEVNPQIAAKTTLIM
HHHCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEE
ATGQQPGALVDALLAFREQHIVITKLESRPINGNPWEEMFYLDVQANLNDPAMLRALHDL
ECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHH
QALTRSQKILGCYPSENVVPVAPTGQS
HHHHHCCHHEEECCCCCEEECCCCCCC
>Mature Secondary Structure 
STLNPLLTLREQISAVDSQLLALLGERRRLAEQVARTKQALHHPVRDRARERDLLLSLI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHH
EQGKPLQLDAHFITRLFQLIIEDSVLTQQALLQQSYLATAAARIAFLGPKGSYSHLAARH
HCCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHHHHHH
YAARYFDQMLECGCQRFQDVFAQVENGQADYAVLPIENTSSGAINDVYDLLQHTSLSIVG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCHHHHHHHHHHCCHHHHE
ELTLPIEHCLLIAGEGDINTLTTVYSHPQPFQQCSQFLSRYPQWHIEYCESTAAAMEKVA
EEHCCHHHEEEEECCCCCCHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
ALCSPQAAALGSADGGNLYGLQPLAHDLANQAQNMTRFIVLARKAIEVNPQIAAKTTLIM
HHHCCCHHHCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHEEEEEE
ATGQQPGALVDALLAFREQHIVITKLESRPINGNPWEEMFYLDVQANLNDPAMLRALHDL
ECCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHH
QALTRSQKILGCYPSENVVPVAPTGQS
HHHHHCCHHEEECCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]