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The map label for this gene is yaaU [H]

Identifier: 238920841

GI number: 238920841

Start: 2854663

End: 2855979

Strand: Direct

Name: yaaU [H]

Synonym: NT01EI_2967

Alternate gene names: 238920841

Gene position: 2854663-2855979 (Clockwise)

Preceding gene: 238920840

Following gene: 238920843

Centisome position: 74.88

GC content: 61.81

Gene sequence:

>1317_bases
ATGGAACAGCATAAAAGATTCGATGACATCCGTTTTACACCGGTGCACCGCAAGATCATGCTGTGGGGGAGCGGAGGCCC
GTTCCTCGATGGCTATGTTCTGGTGATTATCGGCATCGCCCTCGAACAGCTGACCCCCTTGCTGCAACTGGACGCCAACT
GGATAGGGATGGTCGGCGCCGCCACGCTGGTCGGGCTGTTTATCGGCACCTCGCTGTTCGGCTATGTGGCTGATCGGGTT
GGGCGCCGCCTGATGTTTCTGATCGACATCATCGCCATCGGCGTGATCTCTGCCGCCACCATGTTTGTCACCTCGCCGCT
GGAGCTGGTGATCCTACGCTTTCTGATCGGCATCGTTATCGGTGCCGACTACCCCATCGCCACCTCGATGATCGCCGAAT
TCTCCTCCACCAAACAGCGCGCCTTCACCATGGGGTTTATCGCCGCCATGTGGTATATCGGCGCCACCACCGCCGATCTG
GTGGGCTATCTGCTGTACGATGTGGAAAACGGCTGGCGCTGGATGCTGGGCAGTGCGATCGTTCCCTGCATCATCATCTT
ACTGGGCCGGGTCGAGCTGCCGGAATCGCCGCGCTGGCTGATCCGCAAGGGGCGCCACGCAGAATGCCGCGCGCTGATGA
TCAAGCTGTTCGGCCAGCCTGTGACCTTTGACGACGAAGCTCCGCAAGAGACCCGCTACCGCGATATCTTCAGCCGCCGT
CATCTCTCCTCGATCCTGTTCGTCGCCGCCATCTGGACCTGTCAGGTGATCCCCATGTTCGCCATCTACACCTTTGGCCC
GCAGATCGTCACCCTGCTGGGGCTGGAGCAGGGGCGGGAGGCGGTGCTGGGCAACGTGGTGATCAGCCTGTTCTTCATGC
TCGGCTGCCTGCCGGCCATGTACTGGCTCAACAGCGTTGGCCGCCGTCCGCTGCTGATCGGCAGTTTCGCCATCATGACC
CTGTCGCTGCTGATGCTGGGGCTGGTCGATCAGCCCGGGATCCTGCTGATCGTCAGCGCCTTCGCCCTGTACGCCTTCTT
CTCCGGCGGCCCGGGGATCCTGCAGTGGCTCTATCCCAATGAACTGTTTCCCACGGCGATCCGCGCCTCGGCGGTCGGCG
CCGCCATGTCACTGAGCCGCATCGGCACCGTGGTCTCAACCTACGCCCTGCCGCTGTTCATGCAGCAGCACGGGATCTCC
GCCACCATGCTGGCTGGCGCCGGCATTTCGCTGTTCGGTCTGCTGATCTCGGTGATGATGGCGCCGGAGACCCGCGGACT
GTCACTGGAGCAAACCAGCCGGATGAAACTGTTTTAA

Upstream 100 bases:

>100_bases
GAAACAGCGCACCCTGTCCGCCGTATCACAATAATCAGCCACCTGCCGACGCCCCGCCTGTCGCGGGGCTTGCATCGCCA
CTCTTACAGATACCGGGATT

Downstream 100 bases:

>100_bases
CGCCGTCCCGCCCTGTGGGCGGGCAGGTCGGCCACGAATCGGCGGGTAGCCCCAGGGCTACCCGCTGCGCATCAGGCAAT
CTGAAGCTGACGGTAAAAAT

Product: inner membrane metabolite transport protein YgcS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 438

Protein sequence:

>438_residues
MEQHKRFDDIRFTPVHRKIMLWGSGGPFLDGYVLVIIGIALEQLTPLLQLDANWIGMVGAATLVGLFIGTSLFGYVADRV
GRRLMFLIDIIAIGVISAATMFVTSPLELVILRFLIGIVIGADYPIATSMIAEFSSTKQRAFTMGFIAAMWYIGATTADL
VGYLLYDVENGWRWMLGSAIVPCIIILLGRVELPESPRWLIRKGRHAECRALMIKLFGQPVTFDDEAPQETRYRDIFSRR
HLSSILFVAAIWTCQVIPMFAIYTFGPQIVTLLGLEQGREAVLGNVVISLFFMLGCLPAMYWLNSVGRRPLLIGSFAIMT
LSLLMLGLVDQPGILLIVSAFALYAFFSGGPGILQWLYPNELFPTAIRASAVGAAMSLSRIGTVVSTYALPLFMQQHGIS
ATMLAGAGISLFGLLISVMMAPETRGLSLEQTSRMKLF

Sequences:

>Translated_438_residues
MEQHKRFDDIRFTPVHRKIMLWGSGGPFLDGYVLVIIGIALEQLTPLLQLDANWIGMVGAATLVGLFIGTSLFGYVADRV
GRRLMFLIDIIAIGVISAATMFVTSPLELVILRFLIGIVIGADYPIATSMIAEFSSTKQRAFTMGFIAAMWYIGATTADL
VGYLLYDVENGWRWMLGSAIVPCIIILLGRVELPESPRWLIRKGRHAECRALMIKLFGQPVTFDDEAPQETRYRDIFSRR
HLSSILFVAAIWTCQVIPMFAIYTFGPQIVTLLGLEQGREAVLGNVVISLFFMLGCLPAMYWLNSVGRRPLLIGSFAIMT
LSLLMLGLVDQPGILLIVSAFALYAFFSGGPGILQWLYPNELFPTAIRASAVGAAMSLSRIGTVVSTYALPLFMQQHGIS
ATMLAGAGISLFGLLISVMMAPETRGLSLEQTSRMKLF
>Mature_438_residues
MEQHKRFDDIRFTPVHRKIMLWGSGGPFLDGYVLVIIGIALEQLTPLLQLDANWIGMVGAATLVGLFIGTSLFGYVADRV
GRRLMFLIDIIAIGVISAATMFVTSPLELVILRFLIGIVIGADYPIATSMIAEFSSTKQRAFTMGFIAAMWYIGATTADL
VGYLLYDVENGWRWMLGSAIVPCIIILLGRVELPESPRWLIRKGRHAECRALMIKLFGQPVTFDDEAPQETRYRDIFSRR
HLSSILFVAAIWTCQVIPMFAIYTFGPQIVTLLGLEQGREAVLGNVVISLFFMLGCLPAMYWLNSVGRRPLLIGSFAIMT
LSLLMLGLVDQPGILLIVSAFALYAFFSGGPGILQWLYPNELFPTAIRASAVGAAMSLSRIGTVVSTYALPLFMQQHGIS
ATMLAGAGISLFGLLISVMMAPETRGLSLEQTSRMKLF

Specific function: Unknown

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=436, Percent_Identity=23.1651376146789, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI31542327, Length=389, Percent_Identity=24.6786632390745, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI21553331, Length=314, Percent_Identity=23.5668789808917, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI90669191, Length=333, Percent_Identity=26.4264264264264, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI24497497, Length=333, Percent_Identity=26.4264264264264, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI203098995, Length=326, Percent_Identity=26.9938650306748, Blast_Score=78, Evalue=2e-14,
Organism=Homo sapiens, GI302148518, Length=186, Percent_Identity=30.6451612903226, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4507005, Length=347, Percent_Identity=23.9193083573487, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI8923870, Length=390, Percent_Identity=25.6410256410256, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI166064021, Length=386, Percent_Identity=23.5751295336788, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI216548223, Length=171, Percent_Identity=28.6549707602339, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI11415038, Length=411, Percent_Identity=24.5742092457421, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI4506999, Length=451, Percent_Identity=22.8381374722838, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI23510410, Length=197, Percent_Identity=27.4111675126904, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI7662270, Length=192, Percent_Identity=23.4375, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI213021148, Length=435, Percent_Identity=22.7586206896552, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI166795299, Length=343, Percent_Identity=24.4897959183673, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI5902090, Length=403, Percent_Identity=25.0620347394541, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI24497490, Length=414, Percent_Identity=23.1884057971014, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI73695465, Length=166, Percent_Identity=27.1084337349398, Blast_Score=66, Evalue=7e-11,
Organism=Escherichia coli, GI1786229, Length=437, Percent_Identity=75.0572082379863, Blast_Score=687, Evalue=0.0,
Organism=Escherichia coli, GI87082159, Length=427, Percent_Identity=34.8946135831382, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI1790463, Length=457, Percent_Identity=23.4135667396061, Blast_Score=101, Evalue=9e-23,
Organism=Escherichia coli, GI1789207, Length=407, Percent_Identity=21.8673218673219, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789312, Length=427, Percent_Identity=23.6533957845433, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1788074, Length=425, Percent_Identity=22.1176470588235, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788068, Length=467, Percent_Identity=23.7687366167024, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87082231, Length=192, Percent_Identity=25.5208333333333, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17565976, Length=332, Percent_Identity=24.6987951807229, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71986689, Length=360, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=360, Percent_Identity=24.4444444444444, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25145172, Length=402, Percent_Identity=25.1243781094527, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71980582, Length=398, Percent_Identity=25.3768844221106, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71980584, Length=398, Percent_Identity=25.3768844221106, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17565978, Length=332, Percent_Identity=21.9879518072289, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193206721, Length=433, Percent_Identity=22.1709006928406, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI212645980, Length=349, Percent_Identity=25.214899713467, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6323512, Length=453, Percent_Identity=22.075055187638, Blast_Score=93, Evalue=7e-20,
Organism=Saccharomyces cerevisiae, GI6319718, Length=371, Percent_Identity=25.8760107816712, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6320595, Length=175, Percent_Identity=30.2857142857143, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324469, Length=427, Percent_Identity=22.248243559719, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320766, Length=425, Percent_Identity=21.1764705882353, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324400, Length=425, Percent_Identity=21.1764705882353, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24644778, Length=429, Percent_Identity=25.8741258741259, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI19922616, Length=389, Percent_Identity=24.9357326478149, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24644782, Length=373, Percent_Identity=23.8605898123324, Blast_Score=75, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28573193, Length=373, Percent_Identity=23.8605898123324, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24668440, Length=410, Percent_Identity=24.1463414634146, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI161080349, Length=349, Percent_Identity=24.9283667621776, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24654932, Length=349, Percent_Identity=24.9283667621776, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI17737517, Length=349, Percent_Identity=24.9283667621776, Blast_Score=69, Evalue=9e-12,
Organism=Drosophila melanogaster, GI161080353, Length=349, Percent_Identity=24.9283667621776, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640198, Length=199, Percent_Identity=24.6231155778894, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640196, Length=199, Percent_Identity=24.6231155778894, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24640200, Length=199, Percent_Identity=24.6231155778894, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR016196
- InterPro:   IPR005828 [H]

Pfam domain/function: PF00083 Sugar_tr [H]

EC number: NA

Molecular weight: Translated: 48211; Mature: 48211

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEQHKRFDDIRFTPVHRKIMLWGSGGPFLDGYVLVIIGIALEQLTPLLQLDANWIGMVGA
CCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ATLVGLFIGTSLFGYVADRVGRRLMFLIDIIAIGVISAATMFVTSPLELVILRFLIGIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMIAEFSSTKQRAFTMGFIAAMWYIGATTADLVGYLLYDVENGWRWMLGSAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
VPCIIILLGRVELPESPRWLIRKGRHAECRALMIKLFGQPVTFDDEAPQETRYRDIFSRR
HHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HLSSILFVAAIWTCQVIPMFAIYTFGPQIVTLLGLEQGREAVLGNVVISLFFMLGCLPAM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
YWLNSVGRRPLLIGSFAIMTLSLLMLGLVDQPGILLIVSAFALYAFFSGGPGILQWLYPN
HHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEECCCC
ELFPTAIRASAVGAAMSLSRIGTVVSTYALPLFMQQHGISATMLAGAGISLFGLLISVMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHH
APETRGLSLEQTSRMKLF
CCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MEQHKRFDDIRFTPVHRKIMLWGSGGPFLDGYVLVIIGIALEQLTPLLQLDANWIGMVGA
CCCCCCCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ATLVGLFIGTSLFGYVADRVGRRLMFLIDIIAIGVISAATMFVTSPLELVILRFLIGIVI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHH
GADYPIATSMIAEFSSTKQRAFTMGFIAAMWYIGATTADLVGYLLYDVENGWRWMLGSAI
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHH
VPCIIILLGRVELPESPRWLIRKGRHAECRALMIKLFGQPVTFDDEAPQETRYRDIFSRR
HHHHHHHHCCCCCCCCCHHHHCCCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHH
HLSSILFVAAIWTCQVIPMFAIYTFGPQIVTLLGLEQGREAVLGNVVISLFFMLGCLPAM
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHH
YWLNSVGRRPLLIGSFAIMTLSLLMLGLVDQPGILLIVSAFALYAFFSGGPGILQWLYPN
HHHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCHHEEECCCC
ELFPTAIRASAVGAAMSLSRIGTVVSTYALPLFMQQHGISATMLAGAGISLFGLLISVMM
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHCCCHHHHHHHHHHHH
APETRGLSLEQTSRMKLF
CCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503 [H]