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The map label for this gene is fixC [H]

Identifier: 238920839

GI number: 238920839

Start: 2852922

End: 2854268

Strand: Direct

Name: fixC [H]

Synonym: NT01EI_2965

Alternate gene names: 238920839

Gene position: 2852922-2854268 (Clockwise)

Preceding gene: 238920838

Following gene: 238920840

Centisome position: 74.83

GC content: 63.47

Gene sequence:

>1347_bases
ATGGCCGGTGCCGTCACACCGGCGCCGGCCGCATTATCTGCCACTGGAGACACCATGTCTGAAGATGCATTTGACGCAAT
TATTGTCGGCGCCGGTCTGGCCGGTTGCGTAGCCGCGCTGGTTCTGGCGCGCGCCGGAGCCAACGTGCTGGTGATTGAGC
GCGGCAACTACGCCGGCGCCAAAAACGTCACCGGCGGTCGGCTGTATGCCCACACTCTGGAGCGCATCATTCCCGGATTT
GCCGGGCAGGCGCCGGTTGAGCGCCGTATTACCCACGAGAAGATCTCCTTTCTCACCGCCGACAGCGCCGTCACCCTGGA
CTACCACAACGCCCGCGACGGGGTGGCTGAGACGGCCTCCTATTCGGTACTGCGCGGTAAATTTGATACCTGGCTGATGG
AGCAGGCCGAAGCGGCCGGCGCCCAGTTTATCCCCGGCATCCGTGTCGATCGTCTGATCCAGCGCGATGGCCGTGTCGTC
GGCGTAGAGGCCGACGGCGACGAGCTGGAGGCCAATGTGGTGATCCTGGCCGAAGGGGTTAACGCCCTGCTGGCCGAACA
GATCGGCATGGTGCAACCGCGGGTCGAGGCCAAAAACGTCGCCGTGGGGGTCAAAGAGCTGATCGAACTGCCGCGCGAGC
TGCTGGAGGCGCGTTTTGCCCTGCAGGGGAACGACGGCACCGCCTGGCTGTTCGCCGGCACCCCCTCCGATGGCCTGATG
GGCGGTGGTTTCCTCTACACCAACGGCGACTCCCTGTCGCTGGGGATCGTCTGCGGTCTGCACCACATTGAGCAGGCGGG
GAAATCTATCCCACAGATGCTGGAAGACTTTAAGCGGCACCCGACGGTGCAGCCGCTGATCGAGGGCGGTAAAACCGTCG
AGTACGCCGCCCACGTAGTACCGGAAGCCGGCATCAACATGCAGCCTAAGCTGGTGGCCGACGGCGTACTGCTGGCCGGC
GATGCGGCAGGCATGTGCCTTAACCTGGGCTTTACCATTCGCGGAATGGATCTGGCCATTGCCTCCGGTGAAGCTGCGGC
GCACGCCGTACTGGCCGCCCGCGAAAAGAGCGACTTCAGCGCCGCCGGACTGGCCGAGTATCCGCGTCTGCTGGAGAGCC
TGCCGGTGATGAAAGAGCTGCGCCACTACCGCAAGGTACCGCAGATGATGGATAACCCGCGCATGTTCACCCAATACCCA
CAGCTGGCCGCCGACATCATGTCTGCACTGTTCACCGTCGACGGACGCCCGCCGCAGCCGCTGCGTAAGACCCTGCTGCA
GCACTGTAAGCAGGTCGGCTACCTGAATCTGCTCAAAGACGGCATTAAAGGAGTGACAGCACTATGA

Upstream 100 bases:

>100_bases
GATAAAAATGCCCCGATCTTCCAGTATGCCGACTACGGCATCGTCGGCGATCTGGTAAAAATCGTCCCCGCCCTGACCGA
AGCCCTGAAACGCTAGCCGT

Downstream 100 bases:

>100_bases
GCGAACCGGTTAACGTCGATGTCAAACTGGGCATCAATAAGTTCCATGTCGATGAGGGTCATCCGCATATCATCATCCGC
GAACACCCGAACATGGCGGC

Product: FixC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 448; Mature: 447

Protein sequence:

>448_residues
MAGAVTPAPAALSATGDTMSEDAFDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGAKNVTGGRLYAHTLERIIPGF
AGQAPVERRITHEKISFLTADSAVTLDYHNARDGVAETASYSVLRGKFDTWLMEQAEAAGAQFIPGIRVDRLIQRDGRVV
GVEADGDELEANVVILAEGVNALLAEQIGMVQPRVEAKNVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDGLM
GGGFLYTNGDSLSLGIVCGLHHIEQAGKSIPQMLEDFKRHPTVQPLIEGGKTVEYAAHVVPEAGINMQPKLVADGVLLAG
DAAGMCLNLGFTIRGMDLAIASGEAAAHAVLAAREKSDFSAAGLAEYPRLLESLPVMKELRHYRKVPQMMDNPRMFTQYP
QLAADIMSALFTVDGRPPQPLRKTLLQHCKQVGYLNLLKDGIKGVTAL

Sequences:

>Translated_448_residues
MAGAVTPAPAALSATGDTMSEDAFDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGAKNVTGGRLYAHTLERIIPGF
AGQAPVERRITHEKISFLTADSAVTLDYHNARDGVAETASYSVLRGKFDTWLMEQAEAAGAQFIPGIRVDRLIQRDGRVV
GVEADGDELEANVVILAEGVNALLAEQIGMVQPRVEAKNVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDGLM
GGGFLYTNGDSLSLGIVCGLHHIEQAGKSIPQMLEDFKRHPTVQPLIEGGKTVEYAAHVVPEAGINMQPKLVADGVLLAG
DAAGMCLNLGFTIRGMDLAIASGEAAAHAVLAAREKSDFSAAGLAEYPRLLESLPVMKELRHYRKVPQMMDNPRMFTQYP
QLAADIMSALFTVDGRPPQPLRKTLLQHCKQVGYLNLLKDGIKGVTAL
>Mature_447_residues
AGAVTPAPAALSATGDTMSEDAFDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGAKNVTGGRLYAHTLERIIPGFA
GQAPVERRITHEKISFLTADSAVTLDYHNARDGVAETASYSVLRGKFDTWLMEQAEAAGAQFIPGIRVDRLIQRDGRVVG
VEADGDELEANVVILAEGVNALLAEQIGMVQPRVEAKNVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDGLMG
GGFLYTNGDSLSLGIVCGLHHIEQAGKSIPQMLEDFKRHPTVQPLIEGGKTVEYAAHVVPEAGINMQPKLVADGVLLAGD
AAGMCLNLGFTIRGMDLAIASGEAAAHAVLAAREKSDFSAAGLAEYPRLLESLPVMKELRHYRKVPQMMDNPRMFTQYPQ
LAADIMSALFTVDGRPPQPLRKTLLQHCKQVGYLNLLKDGIKGVTAL

Specific function: Could be part of an electron transfer system required for anaerobic carnitine reduction [H]

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ETF-QO/fixC family [H]

Homologues:

Organism=Homo sapiens, GI119703746, Length=405, Percent_Identity=28.641975308642, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1786227, Length=430, Percent_Identity=69.0697674418605, Blast_Score=592, Evalue=1e-170,
Organism=Escherichia coli, GI1787991, Length=430, Percent_Identity=63.953488372093, Blast_Score=566, Evalue=1e-163,
Organism=Escherichia coli, GI87082155, Length=432, Percent_Identity=41.2037037037037, Blast_Score=303, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI25144720, Length=434, Percent_Identity=28.5714285714286, Blast_Score=121, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6324932, Length=368, Percent_Identity=27.1739130434783, Blast_Score=95, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24652256, Length=403, Percent_Identity=28.7841191066998, Blast_Score=107, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006076
- InterPro:   IPR003042 [H]

Pfam domain/function: PF01266 DAO [H]

EC number: 1.5.5.-

Molecular weight: Translated: 47523; Mature: 47392

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGAVTPAPAALSATGDTMSEDAFDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGA
CCCCCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCC
KNVTGGRLYAHTLERIIPGFAGQAPVERRITHEKISFLTADSAVTLDYHNARDGVAETAS
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCEEEEECCCCCCCHHHHHH
YSVLRGKFDTWLMEQAEAAGAQFIPGIRVDRLIQRDGRVVGVEADGDELEANVVILAEGV
HHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCH
NALLAEQIGMVQPRVEAKNVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDGLM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCC
GGGFLYTNGDSLSLGIVCGLHHIEQAGKSIPQMLEDFKRHPTVQPLIEGGKTVEYAAHVV
CCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEHHHHHC
PEAGINMQPKLVADGVLLAGDAAGMCLNLGFTIRGMDLAIASGEAAAHAVLAAREKSDFS
CCCCCCCCCCEEECCEEEECCCCCEEEECCEEEECCEEEEECCCHHHHHHHHHHCCCCCC
AAGLAEYPRLLESLPVMKELRHYRKVPQMMDNPRMFTQYPQLAADIMSALFTVDGRPPQP
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
LRKTLLQHCKQVGYLNLLKDGIKGVTAL
HHHHHHHHHHHCCHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AGAVTPAPAALSATGDTMSEDAFDAIIVGAGLAGCVAALVLARAGANVLVIERGNYAGA
CCCCCCCCCEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCCCC
KNVTGGRLYAHTLERIIPGFAGQAPVERRITHEKISFLTADSAVTLDYHNARDGVAETAS
CCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHEEECCCEEEEECCCCCCCHHHHHH
YSVLRGKFDTWLMEQAEAAGAQFIPGIRVDRLIQRDGRVVGVEADGDELEANVVILAEGV
HHHHHCCHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCEEEEECCCCCCCCCEEEEECCH
NALLAEQIGMVQPRVEAKNVAVGVKELIELPRELLEARFALQGNDGTAWLFAGTPSDGLM
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEECCCCCCCC
GGGFLYTNGDSLSLGIVCGLHHIEQAGKSIPQMLEDFKRHPTVQPLIEGGKTVEYAAHVV
CCCEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEEHHHHHC
PEAGINMQPKLVADGVLLAGDAAGMCLNLGFTIRGMDLAIASGEAAAHAVLAAREKSDFS
CCCCCCCCCCEEECCEEEECCCCCEEEECCEEEECCEEEEECCCHHHHHHHHHHCCCCCC
AAGLAEYPRLLESLPVMKELRHYRKVPQMMDNPRMFTQYPQLAADIMSALFTVDGRPPQP
CCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
LRKTLLQHCKQVGYLNLLKDGIKGVTAL
HHHHHHHHHHHCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]