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The map label for this gene is yeeO [H]

Identifier: 238917318

GI number: 238917318

Start: 1437349

End: 1438674

Strand: Direct

Name: yeeO [H]

Synonym: EUBELI_01393

Alternate gene names: 238917318

Gene position: 1437349-1438674 (Clockwise)

Preceding gene: 238917313

Following gene: 238917328

Centisome position: 67.03

GC content: 39.74

Gene sequence:

>1326_bases
ATGTTTACATCTAAAGATTTAAAGAAGCTTATTATTCCTCTGATATTTGAACAGCTGCTGGCTGTCAGCGTAGGTTTTGT
TGATACATTCATGGTATCAATAGCAGGAGAGGCGGCAGTTTCAGGTGTCGCACTTGTTGATAATATAAGCAACCTGCTTA
TCCAGATATTATCAGCTCTTGCAACCGGAGGTGCTGTTGTATGCAGCCAGTATCTTGGCAGCAGGAACATTGATATGTCC
AAGAAATCTGCCGGACAGCTTATATTTATTATGAGTGCACTATCATCATTACTAATGGTTATCTCTCTCATAGGCAATCA
CGGTATCATCAATTTCATATTTGGCAAGATTGAAACAGATGTATTTGAAAGTGCAAGTATATATTTCTATATAACAGCAA
TCTCATACCCGTTCCTCGGTGTTTATAATGCAGGTGCAGCTCTTTTTAGAAGTATTGGAAACAGCAAGATAAGTATGAAC
ACAAGCCTTATCATGAACATAATCAATATTTGTGGGAATGCTTTATTTATATTTGTATTTGATATGGGAGTTGCCGGTGT
AGCTTTAGCCACTCTTATTTCGCGAATCATATCAGCCATAATTATTATTGGATTTATGTTCAGAACAGAATCAGCAATAA
GAATAAAGACCTGCAAAGATTTTCTTCCATCACCTTCTATCATTAAGAAGATTCTGTCTATTGGTCTTCCGAGCGGATTG
GAAAACGGCATGTTCCAGATAGGTAAGCTTTCTGTTTCAAGCCTTGTTTCAACATTTGGTACTGCTGCCATCGCTGCCAA
CTCTGTTGCCAATTCTGTTACAATGTTTGCCAATATTCCGGGTAACGCAATTGGCATGGCAATGATTACTGTTATTGGCC
AGTGTATAGGTGCAAAGAAGCCTGATGAAGCCAAAAGATATGGAAAAAAACTTATGTTTATTGCATATGCAGGTATTCTT
GCAACCAACATTGTAATGACAATAGTTGCCGTTCCTGTGGTAGGACTTTTCCATCTGTCACCGGAAGCAACCAAAACCGG
TTTAAGCCTTATCCATTGCTTCTCAATTGTAGCAATATTCATATGGCCACTTAGCTTTACTATGCCTAATGCTCTCCGTG
CTGCCGGTGATGCCAAATACACAATGATGGTAAGCATCTTCTCTATGTGGGCATTCCGTGTGGGAAGCAGTTACCTTCTT
GGTGGTACATTAGGACTTGGCGTGCTCGGTGTATGGTTTGGTATGTTCATCGACTGGGGATTCCGTTCACTTGCATTCCT
TATAAGATTCATACGTGGAAAATGGACACAGAAGGCGGTTATATGA

Upstream 100 bases:

>100_bases
TATGTATTTTGCATTAAATACAGCTACTTTTCTTATGTTTTCACATAAATTATTGTTTTATATTATTAAGATATGCTATG
TATTAATATAGGAGATTATT

Downstream 100 bases:

>100_bases
TGATAATTATATGACAGTCTGATGTCTGTGAACTGTCTCTTAACACCGGATATCTACTGTCAGATGGACGACAAGTCGTC
TAATTCTGGATATACAATGT

Product: MATE family multidrug resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 441; Mature: 441

Protein sequence:

>441_residues
MFTSKDLKKLIIPLIFEQLLAVSVGFVDTFMVSIAGEAAVSGVALVDNISNLLIQILSALATGGAVVCSQYLGSRNIDMS
KKSAGQLIFIMSALSSLLMVISLIGNHGIINFIFGKIETDVFESASIYFYITAISYPFLGVYNAGAALFRSIGNSKISMN
TSLIMNIINICGNALFIFVFDMGVAGVALATLISRIISAIIIIGFMFRTESAIRIKTCKDFLPSPSIIKKILSIGLPSGL
ENGMFQIGKLSVSSLVSTFGTAAIAANSVANSVTMFANIPGNAIGMAMITVIGQCIGAKKPDEAKRYGKKLMFIAYAGIL
ATNIVMTIVAVPVVGLFHLSPEATKTGLSLIHCFSIVAIFIWPLSFTMPNALRAAGDAKYTMMVSIFSMWAFRVGSSYLL
GGTLGLGVLGVWFGMFIDWGFRSLAFLIRFIRGKWTQKAVI

Sequences:

>Translated_441_residues
MFTSKDLKKLIIPLIFEQLLAVSVGFVDTFMVSIAGEAAVSGVALVDNISNLLIQILSALATGGAVVCSQYLGSRNIDMS
KKSAGQLIFIMSALSSLLMVISLIGNHGIINFIFGKIETDVFESASIYFYITAISYPFLGVYNAGAALFRSIGNSKISMN
TSLIMNIINICGNALFIFVFDMGVAGVALATLISRIISAIIIIGFMFRTESAIRIKTCKDFLPSPSIIKKILSIGLPSGL
ENGMFQIGKLSVSSLVSTFGTAAIAANSVANSVTMFANIPGNAIGMAMITVIGQCIGAKKPDEAKRYGKKLMFIAYAGIL
ATNIVMTIVAVPVVGLFHLSPEATKTGLSLIHCFSIVAIFIWPLSFTMPNALRAAGDAKYTMMVSIFSMWAFRVGSSYLL
GGTLGLGVLGVWFGMFIDWGFRSLAFLIRFIRGKWTQKAVI
>Mature_441_residues
MFTSKDLKKLIIPLIFEQLLAVSVGFVDTFMVSIAGEAAVSGVALVDNISNLLIQILSALATGGAVVCSQYLGSRNIDMS
KKSAGQLIFIMSALSSLLMVISLIGNHGIINFIFGKIETDVFESASIYFYITAISYPFLGVYNAGAALFRSIGNSKISMN
TSLIMNIINICGNALFIFVFDMGVAGVALATLISRIISAIIIIGFMFRTESAIRIKTCKDFLPSPSIIKKILSIGLPSGL
ENGMFQIGKLSVSSLVSTFGTAAIAANSVANSVTMFANIPGNAIGMAMITVIGQCIGAKKPDEAKRYGKKLMFIAYAGIL
ATNIVMTIVAVPVVGLFHLSPEATKTGLSLIHCFSIVAIFIWPLSFTMPNALRAAGDAKYTMMVSIFSMWAFRVGSSYLL
GGTLGLGVLGVWFGMFIDWGFRSLAFLIRFIRGKWTQKAVI

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=448, Percent_Identity=31.6964285714286, Blast_Score=200, Evalue=2e-52,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 47184; Mature: 47184

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTSKDLKKLIIPLIFEQLLAVSVGFVDTFMVSIAGEAAVSGVALVDNISNLLIQILSAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGGAVVCSQYLGSRNIDMSKKSAGQLIFIMSALSSLLMVISLIGNHGIINFIFGKIETD
HCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VFESASIYFYITAISYPFLGVYNAGAALFRSIGNSKISMNTSLIMNIINICGNALFIFVF
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHH
DMGVAGVALATLISRIISAIIIIGFMFRTESAIRIKTCKDFLPSPSIIKKILSIGLPSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHCCCCCCC
ENGMFQIGKLSVSSLVSTFGTAAIAANSVANSVTMFANIPGNAIGMAMITVIGQCIGAKK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHCCCC
PDEAKRYGKKLMFIAYAGILATNIVMTIVAVPVVGLFHLSPEATKTGLSLIHCFSIVAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IWPLSFTMPNALRAAGDAKYTMMVSIFSMWAFRVGSSYLLGGTLGLGVLGVWFGMFIDWG
HHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
FRSLAFLIRFIRGKWTQKAVI
HHHHHHHHHHHHCCCHHCCCC
>Mature Secondary Structure
MFTSKDLKKLIIPLIFEQLLAVSVGFVDTFMVSIAGEAAVSGVALVDNISNLLIQILSAL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATGGAVVCSQYLGSRNIDMSKKSAGQLIFIMSALSSLLMVISLIGNHGIINFIFGKIETD
HCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
VFESASIYFYITAISYPFLGVYNAGAALFRSIGNSKISMNTSLIMNIINICGNALFIFVF
HHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHH
DMGVAGVALATLISRIISAIIIIGFMFRTESAIRIKTCKDFLPSPSIIKKILSIGLPSGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHCCCHHHHHHHHHCCCCCCC
ENGMFQIGKLSVSSLVSTFGTAAIAANSVANSVTMFANIPGNAIGMAMITVIGQCIGAKK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHCCCC
PDEAKRYGKKLMFIAYAGILATNIVMTIVAVPVVGLFHLSPEATKTGLSLIHCFSIVAIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IWPLSFTMPNALRAAGDAKYTMMVSIFSMWAFRVGSSYLLGGTLGLGVLGVWFGMFIDWG
HHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHH
FRSLAFLIRFIRGKWTQKAVI
HHHHHHHHHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]