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The map label for this gene is hupA [H]

Identifier: 238917311

GI number: 238917311

Start: 1429296

End: 1429595

Strand: Direct

Name: hupA [H]

Synonym: EUBELI_01386

Alternate gene names: 238917311

Gene position: 1429296-1429595 (Clockwise)

Preceding gene: 238917310

Following gene: 238917312

Centisome position: 66.66

GC content: 42.0

Gene sequence:

>300_bases
ATGAATAAGTCAGAATTAGTTGCTGCTATCGCAGAAAAGGCTGAGCTTTCTAAGAAGGACGCAGAGAAGGCTGTTAAGGC
TTTTACAGACACTGTTGCAGAACAGTTAAAGGCTGGAGAAAAGATCCAGTTAGTAGGTTTCGGTACATTTGAAGTTGCTG
AAAGAGCTGCAAGAACAGGTAAGAATCCTCAGACAGGAAAGGCTATCCAGATTCCTGCTTCTAAGGCACCTAAGTTCAAG
GCTGGTAAGGCTTTAAAGGATGTTGTAAACACTCCAGCTAAGAAGTCTAAGAAGAAGTAA

Upstream 100 bases:

>100_bases
TCCCCATTTTGAGCCACTTTTTATTGACAAATTATCAATCTAGGAGTATAAATAATTTATACTTATTATTACTTAATTTT
TTAAGGAGGACAATTTAATT

Downstream 100 bases:

>100_bases
TTATTGAATGACTTTTAAAGGCTGTCACTTATGTGGCAGCCTTTTTTCTCTTTATTTAATTAAGTTAAAAGAATCGAGGT
TTATTATGGAAATCGAGCGT

Product: DNA-binding protein HU-beta

Products: NA

Alternate protein names: DNA-binding protein II; HB [H]

Number of amino acids: Translated: 99; Mature: 99

Protein sequence:

>99_residues
MNKSELVAAIAEKAELSKKDAEKAVKAFTDTVAEQLKAGEKIQLVGFGTFEVAERAARTGKNPQTGKAIQIPASKAPKFK
AGKALKDVVNTPAKKSKKK

Sequences:

>Translated_99_residues
MNKSELVAAIAEKAELSKKDAEKAVKAFTDTVAEQLKAGEKIQLVGFGTFEVAERAARTGKNPQTGKAIQIPASKAPKFK
AGKALKDVVNTPAKKSKKK
>Mature_99_residues
MNKSELVAAIAEKAELSKKDAEKAVKAFTDTVAEQLKAGEKIQLVGFGTFEVAERAARTGKNPQTGKAIQIPASKAPKFK
AGKALKDVVNTPAKKSKKK

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=60, Blast_Score=107, Evalue=2e-25,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=57.3033707865169, Blast_Score=103, Evalue=3e-24,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=40.6593406593407, Blast_Score=78, Evalue=1e-16,
Organism=Escherichia coli, GI1788005, Length=97, Percent_Identity=34.020618556701, Blast_Score=69, Evalue=8e-14,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 10524; Mature: 10524

Theoretical pI: Translated: 10.80; Mature: 10.80

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELVAAIAEKAELSKKDAEKAVKAFTDTVAEQLKAGEKIQLVGFGTFEVAERAARTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
KNPQTGKAIQIPASKAPKFKAGKALKDVVNTPAKKSKKK
CCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNKSELVAAIAEKAELSKKDAEKAVKAFTDTVAEQLKAGEKIQLVGFGTFEVAERAARTG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHCC
KNPQTGKAIQIPASKAPKFKAGKALKDVVNTPAKKSKKK
CCCCCCCEEECCCCCCCCCCCHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3595600; 1633819; 1902464; 1644313; 9384377; 8439548 [H]