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The map label for this gene is arcB [H]

Identifier: 238896716

GI number: 238896716

Start: 4689784

End: 4692123

Strand: Reverse

Name: arcB [H]

Synonym: KP1_4931

Alternate gene names: 238896716

Gene position: 4692123-4689784 (Counterclockwise)

Preceding gene: 238896717

Following gene: 238896715

Centisome position: 89.4

GC content: 55.47

Gene sequence:

>2340_bases
ATGAAGCAAATTCGTATGCTGGCGCAGTATTATGTCGACCTGATGATGAAGCTGGGTCTGGTCCGCTTTTCGATGCTGTT
GGCTCTTGCGCTGGTGGTGCTGGCCATCGTGGTACAGATGGCGGTTACCATGGTGCTGCATGGCCAGGTTGAAAGTATCG
ACGTTATCCGCTCTATCTTCTTTGGCCTGCTGATCACGCCTTGGGCGGTCTACTTTCTCTCGGTGGTGGTGGAGCAGCTC
GAAGAGTCCCGTCAGCGTCTTTCGCGGCTGGTGGACAAGCTGGAGGAGATGCGTGAGCGCGATCTAAAGCTGAACGTCCA
ACTGAAAGATAACATCGCGCAGTTGAATCAGGAGATTGGCGAACGTGAAAAAGCGGAAGCCGAGCGCGAGACCACCCTCG
AGCAGTTGAAGATTGAGATGAAAGAGCGTGAAGAGACGCAGATCCAGCTCGAACAGCAATCCTCCTTTCTGCGCTCTTTC
CTCGATGCTTCCCCGGACCTGGTCTTCTATCGCAATGAGGATAAGGAGTTTTCAGGCTGTAACCGGGCGATGGAGCTGCT
GACCGGCAAAAGCGAGAAACAGCTGATCCACCTCAAACCGCAGGACGTCTATAGCGAAGAGGCGGCGGAAAAGGTACTGG
AGACCGACGAGAAGGTGTTCCGCCATAATGTATCGCTGACCTATGAGCAGTGGCTGGACTATCCCGATGGCCGCAAAGCG
TGCTTTGAAATCCGCAAGGTCCCCTACTACGATCGCGTCGGTAAGCGTCGCGGCCTGATGGGCTTCGGCCGCGATATCAC
CGAACGTAAACGCTATCAGGACGCTCTTGAGCGCGCCAGCCGGGATAAAACCACCTTTATTTCCACCATCAGTCATGAGC
TGCGTACCCCGCTAAACGGGATCGTCGGGCTGAGCCGAATTTTGCTGGATACCGAACTGACCAGCGAACAGGAAAAATAC
CTGAAAACTATCCATGTATCGGCGGTGACGCTGGGGAATATCTTCAATGATATTATCGACATGGACAAAATGGAGCGCCG
CAAGGTGCAGCTCGATAACCAGCCGGTGGACTTCACCAGCTTCCTTGCCGACCTTGAAAACCTATCCGGCCTGCAGGCAC
AGCAGAAGGGGCTGCGCTTTGTGCTGGAGCCGAGCCTGCCGCTGCCGCATAAGGTAATCACGGATGGGACCCGCCTGCGG
CAGATCCTGTGGAATCTTATCAGTAACGCCGTGAAGTTTACCCCGCAGGGCGGAGGGGTGAACGTCCGCGTGCGCTATGA
CGAAGGCGATATCCTGCATTTCGAAGTGGAAGACTCCGGAATTGGTATTCCTGAAGCGGAACAGGACAAAATTTTCGCCA
TGTATTACCAGGTCAAAGACAGCCACGGCGGCAAACCGGCCACCGGAACCGGGATTGGTCTCGCCGTCTCGCGTCGCCTG
GCGCGTAATATGGGCGGTGATATCAGCGTTACCAGCCAGCCGGGTAAAGGGGCGACCTTTACGCTTACCGTCCATGCGCC
TGCCATTGCGGAAGAAGTGGAAGATACGCTGGCGGAAGACGACATGCCATTACCGGCGCTCAACGTGCTGCTGGTTGAGG
ACATTGAGCTCAACGTTATTGTGGCCCGTTCAGTGCTGGAAAAACTGGGTAACAGCGTTGATGTGGCGATGACCGGGAAA
GCCGCGCTGGAGATGTTTGAGCCAGGCGAATATGACCTTGTGCTGTTGGATATTCAGTTACCGGACATGACCGGACTGGA
TATTTCCCGGGAACTGAAACAGCGCTTTGCCGCTGACGAGCTACCGCCGCTGGTCGCCCTCACCGCCAACGTGCTGAAGA
ATAAAAAAGAGTATCTCGACGCCGGGATGGACGATGTGTTGAGTAAGCCGCTATCGGTGCCAGCGCTAACGGCCATGATC
AAGAAATTCTGGGATGCACCGGATGAGGAAGCGCAGGAAGCGCCGGCGGCCGATCTGCATAAAGCCGACGCGGTGCTGGA
TACCGATATGCTGGAGCAATATATCGAGCTGGTGGGACCGAAGCTTATCAACGATGGTCTCGCGGTGTTTGAGAAGATGA
TGCCGGGCTACATGTCCGTTCTGGAGTCTAATCTGACCGCCCGCGACCAAAAAGGGATTGTCGAAGAGGGGCATAAGATC
AAAGGGGCGGCCGGTTCTATCGGACTGCGCCACATCCAGCAGCTGGGCCAGCAGATCCAGACTCCGGATCTGCCTGCCTG
GTCTGATAATGTCGCTGAATGGGTTGAAGAGATGAAATCCGAGTGGCAAAACGATGTAGCGGTACTGAAGGCGTGGGTGG
CGAAAGCCAGCAAAAAATGA

Upstream 100 bases:

>100_bases
CGGCCGCCGTATCGACTCCTGCCCGCATTTTTTGCACAACTTACAGCGCATTGCTCAGAATTGAGTATTATTGTGCGGAG
TTGTCGTGAAGGAATCCCCT

Downstream 100 bases:

>100_bases
CCCCGGACAGACCGGGGTGCGCGAATACTGCGCCAACACCAGGGAACTGGTGGTTGAGCCAGTGTTGTTTGAGTGATGTT
GTTACGTGGCGCAACCGAAG

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 779; Mature: 779

Protein sequence:

>779_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEEMRERDLKLNVQLKDNIAQLNQEIGEREKAEAERETTLEQLKIEMKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLIHLKPQDVYSEEAAEKVLETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRRGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTSEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSGLQAQQKGLRFVLEPSLPLPHKVITDGTRLR
QILWNLISNAVKFTPQGGGVNVRVRYDEGDILHFEVEDSGIGIPEAEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRL
ARNMGGDISVTSQPGKGATFTLTVHAPAIAEEVEDTLAEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGK
AALEMFEPGEYDLVLLDIQLPDMTGLDISRELKQRFAADELPPLVALTANVLKNKKEYLDAGMDDVLSKPLSVPALTAMI
KKFWDAPDEEAQEAPAADLHKADAVLDTDMLEQYIELVGPKLINDGLAVFEKMMPGYMSVLESNLTARDQKGIVEEGHKI
KGAAGSIGLRHIQQLGQQIQTPDLPAWSDNVAEWVEEMKSEWQNDVAVLKAWVAKASKK

Sequences:

>Translated_779_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEEMRERDLKLNVQLKDNIAQLNQEIGEREKAEAERETTLEQLKIEMKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLIHLKPQDVYSEEAAEKVLETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRRGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTSEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSGLQAQQKGLRFVLEPSLPLPHKVITDGTRLR
QILWNLISNAVKFTPQGGGVNVRVRYDEGDILHFEVEDSGIGIPEAEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRL
ARNMGGDISVTSQPGKGATFTLTVHAPAIAEEVEDTLAEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGK
AALEMFEPGEYDLVLLDIQLPDMTGLDISRELKQRFAADELPPLVALTANVLKNKKEYLDAGMDDVLSKPLSVPALTAMI
KKFWDAPDEEAQEAPAADLHKADAVLDTDMLEQYIELVGPKLINDGLAVFEKMMPGYMSVLESNLTARDQKGIVEEGHKI
KGAAGSIGLRHIQQLGQQIQTPDLPAWSDNVAEWVEEMKSEWQNDVAVLKAWVAKASKK
>Mature_779_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVDKLEEMRERDLKLNVQLKDNIAQLNQEIGEREKAEAERETTLEQLKIEMKEREETQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLIHLKPQDVYSEEAAEKVLETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRRGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTSEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSGLQAQQKGLRFVLEPSLPLPHKVITDGTRLR
QILWNLISNAVKFTPQGGGVNVRVRYDEGDILHFEVEDSGIGIPEAEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRL
ARNMGGDISVTSQPGKGATFTLTVHAPAIAEEVEDTLAEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGK
AALEMFEPGEYDLVLLDIQLPDMTGLDISRELKQRFAADELPPLVALTANVLKNKKEYLDAGMDDVLSKPLSVPALTAMI
KKFWDAPDEEAQEAPAADLHKADAVLDTDMLEQYIELVGPKLINDGLAVFEKMMPGYMSVLESNLTARDQKGIVEEGHKI
KGAAGSIGLRHIQQLGQQIQTPDLPAWSDNVAEWVEEMKSEWQNDVAVLKAWVAKASKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=779, Percent_Identity=88.8318356867779, Blast_Score=1394, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=638, Percent_Identity=28.2131661442006, Blast_Score=194, Evalue=1e-50,
Organism=Escherichia coli, GI87081816, Length=516, Percent_Identity=27.7131782945736, Blast_Score=182, Evalue=9e-47,
Organism=Escherichia coli, GI1789149, Length=516, Percent_Identity=29.2635658914729, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=35.6862745098039, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI1788549, Length=417, Percent_Identity=25.6594724220624, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=29.6747967479675, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786600, Length=273, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=28.099173553719, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=23.1818181818182, Blast_Score=73, Evalue=9e-14,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=25.3333333333333, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=243, Percent_Identity=25.5144032921811, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1790300, Length=240, Percent_Identity=27.5, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788393, Length=230, Percent_Identity=24.7826086956522, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788279, Length=270, Percent_Identity=23.7037037037037, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=145, Percent_Identity=33.7931034482759, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6322000, Length=119, Percent_Identity=31.0924369747899, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87745; Mature: 87745

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVDKLEEMRERDLKLNVQLKDNIAQLNQEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHC
EREKAEAERETTLEQLKIEMKEREETQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLIHLKPQDVYSEEAAEKVLETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRRGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELTSEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FLADLENLSGLQAQQKGLRFVLEPSLPLPHKVITDGTRLRQILWNLISNAVKFTPQGGGV
HHHHHHHCCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHEECCCCCCE
NVRVRYDEGDILHFEVEDSGIGIPEAEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRL
EEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
ARNMGGDISVTSQPGKGATFTLTVHAPAIAEEVEDTLAEDDMPLPALNVLLVEDIELNVI
HHCCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCHHHEEEEECCCCHHH
VARSVLEKLGNSVDVAMTGKAALEMFEPGEYDLVLLDIQLPDMTGLDISRELKQRFAADE
HHHHHHHHCCCCEEEEEECHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
LPPLVALTANVLKNKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDAPDEEAQEAPAADLH
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHH
KADAVLDTDMLEQYIELVGPKLINDGLAVFEKMMPGYMSVLESNLTARDQKGIVEEGHKI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCCC
KGAAGSIGLRHIQQLGQQIQTPDLPAWSDNVAEWVEEMKSEWQNDVAVLKAWVAKASKK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVDKLEEMRERDLKLNVQLKDNIAQLNQEIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHC
EREKAEAERETTLEQLKIEMKEREETQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLIHLKPQDVYSEEAAEKVLETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRRGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTELTSEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FLADLENLSGLQAQQKGLRFVLEPSLPLPHKVITDGTRLRQILWNLISNAVKFTPQGGGV
HHHHHHHCCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHEECCCCCCE
NVRVRYDEGDILHFEVEDSGIGIPEAEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRL
EEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHH
ARNMGGDISVTSQPGKGATFTLTVHAPAIAEEVEDTLAEDDMPLPALNVLLVEDIELNVI
HHCCCCCEEEECCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCHHHEEEEECCCCHHH
VARSVLEKLGNSVDVAMTGKAALEMFEPGEYDLVLLDIQLPDMTGLDISRELKQRFAADE
HHHHHHHHCCCCEEEEEECHHHHHHCCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCC
LPPLVALTANVLKNKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDAPDEEAQEAPAADLH
CCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHHHHCCCHHHH
KADAVLDTDMLEQYIELVGPKLINDGLAVFEKMMPGYMSVLESNLTARDQKGIVEEGHKI
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCHHHCCCCC
KGAAGSIGLRHIQQLGQQIQTPDLPAWSDNVAEWVEEMKSEWQNDVAVLKAWVAKASKK
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]