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The map label for this gene is nlpI [H]

Identifier: 238896670

GI number: 238896670

Start: 4648107

End: 4648991

Strand: Reverse

Name: nlpI [H]

Synonym: KP1_4880

Alternate gene names: 238896670

Gene position: 4648991-4648107 (Counterclockwise)

Preceding gene: 238896671

Following gene: 238896669

Centisome position: 88.58

GC content: 50.73

Gene sequence:

>885_bases
ATGAAGCCTTTTTTGCGCTGGTGTTTCGTGGCGACAGCTCTCACGCTGGCAGGATGCAGTAGCACCGCCTGGCGTAAGGA
CGCCGTCCTCGCAGTACCATTGCAACCGACTTTACAGCAAGAAGTGATTCTGGCACGCATGGAACAAATTCTTGCCAGTC
GGGCTTTATCCGATGACGAACGCGCACAGCTTTTATATGAGCGCGGAGTGTTGTATGATAGTCTCGGTCTGAGGGCACTT
GCGCGAAATGATTTTTCACAAGCGCTGGCAATCCGACCCGATATGCCGGAAGTATTCAATTACTTAGGCATTTACTTAAC
GCAGGCAGGCAATTTTGATGCTGCCTATGAAGCGTTTGATTCTGTACTTGAGCTTGATCCAACTTACAACTACGCGCACT
TGAACCGCGGTATCGCCCTGTATTACGGCGGCCGGGCTAAGTTAGCGCAAGATGATCTGCTGGCGTTTTATCAAGACGAT
CCCAATGATCCTTTCCGTAGCCTGTGGCTTTATATCGCCGAGCGTAAACTCGACGAGAAGCGGGCGCTTGAAGCACTCAG
AGAGCGCTTAAACAAGTCGGATAAAGAGCAATGGGGATGGAACATTGTCGAGTTCTACCTTGGCGACATTAGCGAAAAAG
AGCTGATGACTCGTCTGAAGGCAGACGCAACGGATAACACCTCGCTCGCTGAGCATCTCAGTGAAACCAACTTCTATTTA
GGTAAGTACTACCTAAGTCTGGGGGACAAGGACAGCGCTACGGCACTGTTCAAACTGGCGGTCGCCAACAACGTACACAA
CTACGTTGAGCACCGATACGCATTGTTGGAATTATCGCTCTTGGGCCAGGAGCAAGATGACCTGGCAGAATCGGACCAGC
AATAG

Upstream 100 bases:

>100_bases
TAGCCCTCCCGCTTTTGCGGAGGGCGTTTTACGGGCAGGACGCCTCGTTTGCAGCCGGGGAACAGGACGTTCATCCAATC
GTTGTCTTCGGGAGTGGGAA

Downstream 100 bases:

>100_bases
CTGACGAACACATCAGCCCATAGTTTTTTGCTTGCCATCACCTTCGCGGGTGAGGGCGTTGTTGTTCGTTAATACACCTA
CTTTGAGCCGGTTCACACTT

Product: lipoprotein NlpI

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 294; Mature: 294

Protein sequence:

>294_residues
MKPFLRWCFVATALTLAGCSSTAWRKDAVLAVPLQPTLQQEVILARMEQILASRALSDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDD
PNDPFRSLWLYIAERKLDEKRALEALRERLNKSDKEQWGWNIVEFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ

Sequences:

>Translated_294_residues
MKPFLRWCFVATALTLAGCSSTAWRKDAVLAVPLQPTLQQEVILARMEQILASRALSDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDD
PNDPFRSLWLYIAERKLDEKRALEALRERLNKSDKEQWGWNIVEFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ
>Mature_294_residues
MKPFLRWCFVATALTLAGCSSTAWRKDAVLAVPLQPTLQQEVILARMEQILASRALSDDERAQLLYERGVLYDSLGLRAL
ARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDD
PNDPFRSLWLYIAERKLDEKRALEALRERLNKSDKEQWGWNIVEFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ

Specific function: May be involved in cell division. Overexpression of nlpI results in the loss of the rod morphology and the formation of single prolate ellipsoids and pairs of prolate ellipsoids joined by partial constrictions [H]

COG id: COG4785

COG function: function code R; Lipoprotein NlpI, contains TPR repeats

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 TPR repeats [H]

Homologues:

Organism=Escherichia coli, GI1789554, Length=294, Percent_Identity=92.1768707482993, Blast_Score=557, Evalue=1e-160,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 33548; Mature: 33548

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPFLRWCFVATALTLAGCSSTAWRKDAVLAVPLQPTLQQEVILARMEQILASRALSDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDDPNDPFRSLWLYIAERKLDEK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHCCHH
RALEALRERLNKSDKEQWGWNIVEFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
HHHHHHHHHHCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ
EHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC
>Mature Secondary Structure
MKPFLRWCFVATALTLAGCSSTAWRKDAVLAVPLQPTLQQEVILARMEQILASRALSDDE
CCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHH
RAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYEAFD
HHHHHHHHCCHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHH
SVLELDPTYNYAHLNRGIALYYGGRAKLAQDDLLAFYQDDPNDPFRSLWLYIAERKLDEK
HHHHCCCCCCHHHHCCCEEEEECCCCCCCHHHHHEEECCCCCCHHHHHHHHHHHHHCCHH
RALEALRERLNKSDKEQWGWNIVEFYLGDISEKELMTRLKADATDNTSLAEHLSETNFYL
HHHHHHHHHHCCCCHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCEE
GKYYLSLGDKDSATALFKLAVANNVHNYVEHRYALLELSLLGQEQDDLAESDQQ
EHEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]