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The map label for this gene is uppP

Identifier: 238896557

GI number: 238896557

Start: 4536843

End: 4537664

Strand: Reverse

Name: uppP

Synonym: KP1_4748

Alternate gene names: 238896557

Gene position: 4537664-4536843 (Counterclockwise)

Preceding gene: 238896558

Following gene: 238896553

Centisome position: 86.46

GC content: 55.84

Gene sequence:

>822_bases
ATGAGCGATATACACTCGCTGCTGGTGGCGGCAATATTGGGTGTGGTTGAGGGTTTGACAGAGTTTTTACCTGTTTCCAG
TACCGGTCATATGATTATTGTTGGTCATCTGCTGGGGTTTGAAGGTGATACCGCAAATACCTTTGAAGTGGTGATTCAGT
TAGGTTCGATACTCGCCGTGGTGGTGATGTTCTGGCGTCGCCTGTTCGGCCTGATCGGCATCCATTTCGGGAAACCGCCG
GCGCATGAAGGCCAGGGCAGCGGCCGTTTGTCGCTTATCCATATCCTTCTCGGCATGATCCCCGCGGTGGTGATGGGGCT
GATTTTCCATGACACCATTAAATCCTTGTTTAACCCGGTGAACGTGATGTACGCCCTGATTGTCGGCGGCGTATTGCTGA
TTGCAGCGGAAGTGCTGAAGCCGAAACAGCCGCGCGCGGTCGGGATTGACGATATGACCTACCGTCAGGCGTTCGTCATC
GGCTGCTTTCAGTGCCTGGCGCTGTGGCCAGGTTTCTCCCGCTCGGGGGCGACTATCTCCGGCGGCATGCTGATGGGCGT
CAGCCGCTATGCGGCCTCGGAGTTCTCTTTCCTGCTGGCGGTACCGATGATGATGGGCGCCACCGTGCTGGACGTCTACA
AGAGCATCGGCTTCCTGAACATGGGCGACGTCCCGATGTTCGCCGTCGGCTTCGTGATGGCGTTTATCGTGGCGCTGATT
GCGATTAAAACCTTCCTGCAGCTGATCAAACGGATCTCGTTCATTCCGTTCGCTATCTACCGCTTTATCGTCGCGGCAGC
GGTGTACGTGGTCTTCTTCTAA

Upstream 100 bases:

>100_bases
ACGCTGCGGATTACGCGCGCTCTGGCAGCCGGGTTGTGCCTGTTGAACGATACCGTGTTCCTGGTTTTTTTCATTTTACT
TTTTTAAAGGGTTTAATTGG

Downstream 100 bases:

>100_bases
GGCCTGCGCCCTCAGCCTTGCGGCTGGGGGCAACGCTGTTCCTTCCACTGCGCTACCGCCGCAATTCTCCGCCGCGTCAG
CTCCTCGCGAATTTCCGCCC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 273; Mature: 272

Protein sequence:

>273_residues
MSDIHSLLVAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTANTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGKPP
AHEGQGSGRLSLIHILLGMIPAVVMGLIFHDTIKSLFNPVNVMYALIVGGVLLIAAEVLKPKQPRAVGIDDMTYRQAFVI
GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDVYKSIGFLNMGDVPMFAVGFVMAFIVALI
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Sequences:

>Translated_273_residues
MSDIHSLLVAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTANTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGKPP
AHEGQGSGRLSLIHILLGMIPAVVMGLIFHDTIKSLFNPVNVMYALIVGGVLLIAAEVLKPKQPRAVGIDDMTYRQAFVI
GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDVYKSIGFLNMGDVPMFAVGFVMAFIVALI
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
>Mature_272_residues
SDIHSLLVAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTANTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGKPPA
HEGQGSGRLSLIHILLGMIPAVVMGLIFHDTIKSLFNPVNVMYALIVGGVLLIAAEVLKPKQPRAVGIDDMTYRQAFVIG
CFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATVLDVYKSIGFLNMGDVPMFAVGFVMAFIVALIA
IKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=273, Percent_Identity=89.3772893772894, Blast_Score=497, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_KLEP7 (A6TE36)

Other databases:

- EMBL:   CP000647
- RefSeq:   YP_001337087.1
- STRING:   A6TE36
- GeneID:   5342610
- GenomeReviews:   CP000647_GR
- KEGG:   kpn:KPN_03461
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   DTANTFE
- ProtClustDB:   PRK00281
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 29509; Mature: 29378

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x1fe2724c)-; HASH(0x192ec1c0)-; HASH(0x204d2d30)-; HASH(0x204ca404)-; HASH(0x204d5c1c)-; HASH(0x204b89fc)-; HASH(0x204cff3c)-; HASH(0x204d8488)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.5 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
SDIHSLLVAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDTANTFEVVIQLGSILAV
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCCHHHHHHHHHHHHHHH
VVMFWRRLFGLIGIHFGKPPAHEGQGSGRLSLIHILLGMIPAVVMGLIFHDTIKSLFNPV
HHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NVMYALIVGGVLLIAAEVLKPKQPRAVGIDDMTYRQAFVIGCFQCLALWPGFSRSGATIS
HHHHHHHHHHHHHHHHHHHCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEC
GGMLMGVSRYAASEFSFLLAVPMMMGATVLDVYKSIGFLNMGDVPMFAVGFVMAFIVALI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHH
AIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA