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The map label for this gene is speC [H]

Identifier: 238896497

GI number: 238896497

Start: 4476082

End: 4478262

Strand: Reverse

Name: speC [H]

Synonym: KP1_4678

Alternate gene names: 238896497

Gene position: 4478262-4476082 (Counterclockwise)

Preceding gene: 238896499

Following gene: 238896492

Centisome position: 85.32

GC content: 59.61

Gene sequence:

>2181_bases
TTGTCTGAGATTTTTACACTCCCGATACGGGCATTTGCGCTTATGAAATCCATGCACATTGCCGCCAGCTGCGAGCTGGT
CACCCGCTTGTCCACCCACCGTCGCGTTGTGGCGCTGGACAGTACCGATTTTACCGATGTGGCGGCAGTCGTCATCTCCG
TGGCCGACAGTCGCAGCGGCATCCTTACTCTCCTCAGGCGTAGCGGATTTAACCTGCCGGTCTACCTGCTGAGTGAGACG
GCGGTCGACAAGCCGGAGGGGGTGCAGGCGGTGATCGCCGGTAAAGATCAGGAGTGGCTGGAGCTGGAGGCGGCGGCCTG
TGATTATGAAGCGCGTCTGCTGCCGCCGTTTTTCAATACCCTGACCCAGTACGTCGAGATGGATAACAGCACCTTTGCCT
GTCCGGGGCATCAGCACGGGGCGTTTTTCAAAAAGCACCCTGCAGGCCGTCAGTTCTATGACTTTTTTGGCGAAAATGTC
TTTCGCGCCGACATGTGCAACGCCGATGTGAAATTAGGCGATCTGCTGATCCACGAAGGATCGGCCAAGCACGCGCAGAA
GTTCGCTGCGAAGGTGTTCAACGCGGATAAAACCTACTTCGTCCTCAACGGCACCTCGGCGGCCAACAAAGTCGTGACCA
ACGCGCTGTTGACCCGCGGCGATCTGGTGCTGTTCGATCGCAACAACCACAAGTCAAACCATCACGGGGCGCTGATCCAG
GCGGGGGCGACGCCTGTTTACCTGGAAGCCGCGCGCAATCCGTTCGGCTTTATCGGCGGCATTGACGAGCGCTGCTTTGA
TGAGCATTACCTGCGGGATCTCATCCGCGAAGCGGCGCCTGAGAAAGCCAATGCCTCCCGCCCGTTTCGTCTGGCGGTGA
TCCAGCTCGGAACCTACGACGGCACGGTCTATAACGCCCGCCAGGTGGTGGATAAAATAGGCCACCTCTGCGATTACATC
CTGTTCGACTCGGCGTGGGTGGGCTATGAGCAGTTTATCCCAATGATGGCCGACTGCTCGCCGCTGCTGCTGGAGCTGAC
CCCCGACGATCCGGGTATTTTTGTCACCCAGTCCGTGCACAAGCAGCAGGCCGGCTTCTCACAGACGTCGCAGATCCATA
AAAAAGATAACCATCTGCGCGGCCAGGCGCGCTTCTGTCCGCACAAGCGGCTGAATAACGCCTTTATGCTGCATGCCTCC
ACCAGCCCGTTCTATCCGCTGTTCGCCGCGCTGGACGTTAACGCTAAAATCCATGAAGGTGAGAGCGGCCGTCGCCTGTG
GGCCGAGTGCGTGGCGCTGGGCATTGAGGCGCGCAAAGCGATCATCGCCAACTGCAAGATGATCCAGCCCTTTATTCCGC
CGATGGTGGCGGGGCGCCCGTGGCAGGATCACCCGACCGAGGCGATCGCCCGGGAGCGCCGCTTCTTCAGCTTCGAACCC
GACGCGCGCTGGCATGGTTTTGAAGGCTACGCGGACGACCAGTATTTTGTCGACCCGTGCAAGCTGTTGCTGACCACCCT
GGGCATTGACGCGGAGAGCGGGGAGTACAGTGAGTTTGGCATCCCGGCAACCATTCTGGCGCATTATCTGCGTGAAAACG
GCATCGTGCCGGAGAAGTGCGATCTCAACTCGATTCTGTTCCTGCTGACGCCGGCGGAGAGCGCCGAAAAAATGGCGCAG
CTGGTGGCGATGCTGGGGCAGTTTGAACAGCATATTGAAGCGGATACGCCGCTGGCCGATGTGTTGCCGACCATCTATAA
CAAATATCCGGTACGTTATCGCGACTATACCCTGCGCGAGCTGTGCCAGGAGATGCACGATCTGTACGTTAGCTTTGACG
TGAAGAGCCTGCAAAAAGAGATGTTCCGTAAACGGAGCTTCCCAAGGGTGGTGATGAATCCCCAGGATGCCAACCACGAG
TTTATTCGCGGCAACGTTGAGCTGGTGCGTCTGAGCGAGGCGGAAGGCCGCGTCGCGGCGGAGGGGGCGCTGCCGTATCC
GCCGGGCGTGCTGTGCGTGGTGCCCGGCGAGGTCTGGGGCGGCGCCGTGCTGCGCTATTTCCTCGCGCTGGAGGAGGGGG
TCAATATGCTGCCTGGCTTCTCGCCGGAGCTGCAGGGGGTTTACAGCGAGACGGATCCGGACGGCATTAAGCGGCTGTAT
GGCTACGTGCTGAAGGGATAA

Upstream 100 bases:

>100_bases
TGTAGGGCAACAGTAAGATCGGACGCGTCTGCTTTTACTGATGTCCGGCGGTCGGAGCTGAATCCGTCAGACCCGGACAC
ATCGTTGGGCAAGGTCTCCC

Downstream 100 bases:

>100_bases
AAAAACGCCCCGCCGAACAGGCGGGGCGTTTTACTTTTGCCGATCACACGCTCTGCTGGGCGGCGGTCGGTTGTCTGACG
TGTTTGTATTTGAACAGCGC

Product: ornithine decarboxylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 726; Mature: 725

Protein sequence:

>726_residues
MSEIFTLPIRAFALMKSMHIAASCELVTRLSTHRRVVALDSTDFTDVAAVVISVADSRSGILTLLRRSGFNLPVYLLSET
AVDKPEGVQAVIAGKDQEWLELEAAACDYEARLLPPFFNTLTQYVEMDNSTFACPGHQHGAFFKKHPAGRQFYDFFGENV
FRADMCNADVKLGDLLIHEGSAKHAQKFAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQ
AGATPVYLEAARNPFGFIGGIDERCFDEHYLRDLIREAAPEKANASRPFRLAVIQLGTYDGTVYNARQVVDKIGHLCDYI
LFDSAWVGYEQFIPMMADCSPLLLELTPDDPGIFVTQSVHKQQAGFSQTSQIHKKDNHLRGQARFCPHKRLNNAFMLHAS
TSPFYPLFAALDVNAKIHEGESGRRLWAECVALGIEARKAIIANCKMIQPFIPPMVAGRPWQDHPTEAIARERRFFSFEP
DARWHGFEGYADDQYFVDPCKLLLTTLGIDAESGEYSEFGIPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAQ
LVAMLGQFEQHIEADTPLADVLPTIYNKYPVRYRDYTLRELCQEMHDLYVSFDVKSLQKEMFRKRSFPRVVMNPQDANHE
FIRGNVELVRLSEAEGRVAAEGALPYPPGVLCVVPGEVWGGAVLRYFLALEEGVNMLPGFSPELQGVYSETDPDGIKRLY
GYVLKG

Sequences:

>Translated_726_residues
MSEIFTLPIRAFALMKSMHIAASCELVTRLSTHRRVVALDSTDFTDVAAVVISVADSRSGILTLLRRSGFNLPVYLLSET
AVDKPEGVQAVIAGKDQEWLELEAAACDYEARLLPPFFNTLTQYVEMDNSTFACPGHQHGAFFKKHPAGRQFYDFFGENV
FRADMCNADVKLGDLLIHEGSAKHAQKFAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQ
AGATPVYLEAARNPFGFIGGIDERCFDEHYLRDLIREAAPEKANASRPFRLAVIQLGTYDGTVYNARQVVDKIGHLCDYI
LFDSAWVGYEQFIPMMADCSPLLLELTPDDPGIFVTQSVHKQQAGFSQTSQIHKKDNHLRGQARFCPHKRLNNAFMLHAS
TSPFYPLFAALDVNAKIHEGESGRRLWAECVALGIEARKAIIANCKMIQPFIPPMVAGRPWQDHPTEAIARERRFFSFEP
DARWHGFEGYADDQYFVDPCKLLLTTLGIDAESGEYSEFGIPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAQ
LVAMLGQFEQHIEADTPLADVLPTIYNKYPVRYRDYTLRELCQEMHDLYVSFDVKSLQKEMFRKRSFPRVVMNPQDANHE
FIRGNVELVRLSEAEGRVAAEGALPYPPGVLCVVPGEVWGGAVLRYFLALEEGVNMLPGFSPELQGVYSETDPDGIKRLY
GYVLKG
>Mature_725_residues
SEIFTLPIRAFALMKSMHIAASCELVTRLSTHRRVVALDSTDFTDVAAVVISVADSRSGILTLLRRSGFNLPVYLLSETA
VDKPEGVQAVIAGKDQEWLELEAAACDYEARLLPPFFNTLTQYVEMDNSTFACPGHQHGAFFKKHPAGRQFYDFFGENVF
RADMCNADVKLGDLLIHEGSAKHAQKFAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQA
GATPVYLEAARNPFGFIGGIDERCFDEHYLRDLIREAAPEKANASRPFRLAVIQLGTYDGTVYNARQVVDKIGHLCDYIL
FDSAWVGYEQFIPMMADCSPLLLELTPDDPGIFVTQSVHKQQAGFSQTSQIHKKDNHLRGQARFCPHKRLNNAFMLHAST
SPFYPLFAALDVNAKIHEGESGRRLWAECVALGIEARKAIIANCKMIQPFIPPMVAGRPWQDHPTEAIARERRFFSFEPD
ARWHGFEGYADDQYFVDPCKLLLTTLGIDAESGEYSEFGIPATILAHYLRENGIVPEKCDLNSILFLLTPAESAEKMAQL
VAMLGQFEQHIEADTPLADVLPTIYNKYPVRYRDYTLRELCQEMHDLYVSFDVKSLQKEMFRKRSFPRVVMNPQDANHEF
IRGNVELVRLSEAEGRVAAEGALPYPPGVLCVVPGEVWGGAVLRYFLALEEGVNMLPGFSPELQGVYSETDPDGIKRLYG
YVLKG

Specific function: Spermidine biosynthesis from ornithine. [C]

COG id: COG1982

COG function: function code E; Arginine/lysine/ornithine decarboxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Orn/Lys/Arg decarboxylase class-I family [H]

Homologues:

Organism=Escherichia coli, GI87082193, Length=711, Percent_Identity=84.9507735583685, Blast_Score=1285, Evalue=0.0,
Organism=Escherichia coli, GI1786909, Length=719, Percent_Identity=66.3421418636996, Blast_Score=1006, Evalue=0.0,
Organism=Escherichia coli, GI221142684, Length=676, Percent_Identity=32.6923076923077, Blast_Score=352, Evalue=5e-98,
Organism=Escherichia coli, GI1790573, Length=621, Percent_Identity=34.621578099839, Blast_Score=326, Evalue=3e-90,
Organism=Escherichia coli, GI1786384, Length=622, Percent_Identity=34.7266881028939, Blast_Score=324, Evalue=1e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR005308
- InterPro:   IPR011193
- InterPro:   IPR000310
- InterPro:   IPR008286
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF01276 OKR_DC_1; PF03711 OKR_DC_1_C; PF03709 OKR_DC_1_N [H]

EC number: =4.1.1.17 [H]

Molecular weight: Translated: 81253; Mature: 81121

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00703 OKR_DC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIFTLPIRAFALMKSMHIAASCELVTRLSTHRRVVALDSTDFTDVAAVVISVADSRSG
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCHH
ILTLLRRSGFNLPVYLLSETAVDKPEGVQAVIAGKDQEWLELEAAACDYEARLLPPFFNT
HHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECCHHHHH
LTQYVEMDNSTFACPGHQHGAFFKKHPAGRQFYDFFGENVFRADMCNADVKLGDLLIHEG
HHHHHHCCCCEEECCCCCCCCCHHCCCCCCHHHHHHCCCEEEHHHCCCCCEECEEEEECC
SAKHAQKFAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQ
CHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEE
AGATPVYLEAARNPFGFIGGIDERCFDEHYLRDLIREAAPEKANASRPFRLAVIQLGTYD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCC
GTVYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELTPDDPGIFVTQSVH
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHH
KQQAGFSQTSQIHKKDNHLRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEG
HHHCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECC
ESGRRLWAECVALGIEARKAIIANCKMIQPFIPPMVAGRPWQDHPTEAIARERRFFSFEP
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCC
DARWHGFEGYADDQYFVDPCKLLLTTLGIDAESGEYSEFGIPATILAHYLRENGIVPEKC
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DLNSILFLLTPAESAEKMAQLVAMLGQFEQHIEADTPLADVLPTIYNKYPVRYRDYTLRE
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEECCCHHHH
LCQEMHDLYVSFDVKSLQKEMFRKRSFPRVVMNPQDANHEFIRGNVELVRLSEAEGRVAA
HHHHHHHHEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCEEECCEEEEEEECCCCCEEE
EGALPYPPGVLCVVPGEVWGGAVLRYFLALEEGVNMLPGFSPELQGVYSETDPDGIKRLY
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHCCCCCHHHCCCCCCCCHHHHHHHH
GYVLKG
HHHCCC
>Mature Secondary Structure 
SEIFTLPIRAFALMKSMHIAASCELVTRLSTHRRVVALDSTDFTDVAAVVISVADSRSG
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHCCCCHH
ILTLLRRSGFNLPVYLLSETAVDKPEGVQAVIAGKDQEWLELEAAACDYEARLLPPFFNT
HHHHHHHCCCCCEEEEEECCCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCEECCHHHHH
LTQYVEMDNSTFACPGHQHGAFFKKHPAGRQFYDFFGENVFRADMCNADVKLGDLLIHEG
HHHHHHCCCCEEECCCCCCCCCHHCCCCCCHHHHHHCCCEEEHHHCCCCCEECEEEEECC
SAKHAQKFAAKVFNADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKSNHHGALIQ
CHHHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCEEE
AGATPVYLEAARNPFGFIGGIDERCFDEHYLRDLIREAAPEKANASRPFRLAVIQLGTYD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCC
GTVYNARQVVDKIGHLCDYILFDSAWVGYEQFIPMMADCSPLLLELTPDDPGIFVTQSVH
CCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEEHHHH
KQQAGFSQTSQIHKKDNHLRGQARFCPHKRLNNAFMLHASTSPFYPLFAALDVNAKIHEG
HHHCCCHHHHHHHHHHCCCCCCCCCCCHHHCCCEEEEEECCCCCCEEEEEEECCCEEECC
ESGRRLWAECVALGIEARKAIIANCKMIQPFIPPMVAGRPWQDHPTEAIARERRFFSFEP
CCCHHHHHHHHHHHHHHHHHHHHCCHHHCCCCCHHHCCCCCCCCCHHHHHHHHHCCCCCC
DARWHGFEGYADDQYFVDPCKLLLTTLGIDAESGEYSEFGIPATILAHYLRENGIVPEKC
CCCCCCCCCCCCCCEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCC
DLNSILFLLTPAESAEKMAQLVAMLGQFEQHIEADTPLADVLPTIYNKYPVRYRDYTLRE
CCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCEECCCHHHH
LCQEMHDLYVSFDVKSLQKEMFRKRSFPRVVMNPQDANHEFIRGNVELVRLSEAEGRVAA
HHHHHHHHEEEECHHHHHHHHHHHCCCCEEEECCCCCCCCEEECCEEEEEEECCCCCEEE
EGALPYPPGVLCVVPGEVWGGAVLRYFLALEEGVNMLPGFSPELQGVYSETDPDGIKRLY
CCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHCCHHCCCCCHHHCCCCCCCCHHHHHHHH
GYVLKG
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]