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The map label for this gene is fdrA [H]

Identifier: 238893479

GI number: 238893479

Start: 1326950

End: 1328617

Strand: Direct

Name: fdrA [H]

Synonym: KP1_1375

Alternate gene names: 238893479

Gene position: 1326950-1328617 (Clockwise)

Preceding gene: 238893475

Following gene: 238893480

Centisome position: 25.28

GC content: 57.19

Gene sequence:

>1668_bases
ATGATCCATGCCTTTATTAAAAAGGGCTGTTTTCAGGATTCAGTCAGTTTAATGATTATTTCACGTAAGCTGAGTGAGTC
AGAAAATGTCGACGATGTTTCGGTCATGATGGGCACGCCGGCAAATAAAGCGCTGCTGGAAACTACCGGTTTTTGGCATG
ACGATTTTGCCACGGCGACGCCGAATGATATTTGCGTGGCGATCCGTACCGATTGCGCAGATGCATCGGTGACAGAAATG
ATTATCGCCCGTCTGGATGACGCCTTATCCGCCCTGGCGCAGGGAAGCGGACAAAGTCAGAGTCTGAACGTGGTTCGCCG
CTGGCAAAGCGCGATGCAAAAACTGCCGCAGGCCAATATGACCTTAATTTCTGTTGCCGGAGAATATGCCGCAGAGCTGG
CCCATCAGGCGCTCAGTAGTGAGAAAAGCGTGATGATTTTCTCCGACAACGTCACCCTGGAAGATGAAATTGCCCTCAAA
ACCCGCGCCCGTGAGAAAGGATTGTTGGTGATGGGACCTGACTGCGGCACCGCCATGATTGCCGGCACCCCGCTGGCCTT
CGCCAACGTTACACCAGAGGGCAATATCGGGGTGATTGGCGCCTCCGGTACCGGTATCCAGGAACTGGTATCGCAAATTG
CCCTCGGCGGCGAAGGGATCAGCCATGCGATAGGTCTCGGCGGCCGTGATCTGAGCGCGGAAGTGGGGGGCCTTAGTGCG
CAAACGGCGCTGGAAATGCTAACCCAGGATGCGCAGAGCCAGGTACTGGCCTTTGTATCCAAGCCACCTGATGAGGCGGT
GCGCCTGAAGATAATTAACGCAATGAAACGCAGTGCTAAACCGGTGGTGGCGCTATTTCTTGGCTATGTCTCGCCAGTCA
ACCGCGATGAAAACGTCTGGTTTGCCCGCACGCTGGACGAGGCCGGTCGGCTGGCGTGTCTGTTGGCCCGAGTGGTACGC
CACCAGGAAAATCTGACCGCAGTCGCGGATAAGCATATCCGCGGATTATATACCGGCGGCACGTTGGCGGCGGAATCTGC
CGGGCTGCTGGCTGAGCGCCTGAACATCACTCCCGATGAGCATCACCCGCAGGGCATGATGCTCAACGCTCTGGGCCACC
AGATCGTCGACCTCGGCGATGATTTCTACACCGTTGGTCGTCCACACCCGATGATTGATCCCTCCCTGCGTAACCAACTG
ATTGCCGAGCTCGGCGAGCAAACGCAGGTGGGCGTATTGCTGCTGGATGTGGTGATTGGCTATGGCGCCACCGCCGACCC
GGCGGGATCGCTGGTGGAAGCATGCCGGCTGGCCTGGGCATTGAGGAGTGAAAGCCATCCGCTGCACGTTATCGCGACCG
TGACCGGTACCGAAAATGACCCGCAGTGTCGTTCCCGTCAGATTGCCGAGCTGGAAGATGCCGGCGTGGTGGTGGTCGAT
AGCCTCCCGGAAGCCGCACTGCTTGCTGTTGCGCTGATTAGCCCTCAGCGGATGGCGGAGCCCGCACCGCGTTCCAGTCT
GCTGGATGGGGTGGCGGTAATTAATGCCGGTCTGCGCAGTTTTGCGATCGATTTACAGTCCGCCGGAACGCCGGTTGTTC
ACTATCAGTGGGCGCCGATTGCCGGAGGAAATAAAAAACTGGCTCGTTTATTAGAGCGTTTGCAATAA

Upstream 100 bases:

>100_bases
GTGATTTAGGTCACGCCATTGATAATTCCATCCCGTTAGCCTGATTGCAGATTAACCATGCTCATTCAATTGCAATGGGT
GCAATTATTGGGGAGTTATT

Downstream 100 bases:

>100_bases
GAGGTCCCTATGTTTACATCAGTGGCGCAGGCCAATGAGGCAGTAATTGAACGAATTCGGAATGCACGTCCGCACTGGCT
GGATGTGAAGCCGGCAGGTG

Product: membrane protein FdrA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLETTGFWHDDFATATPNDICVAIRTDCADASVTEM
IIARLDDALSALAQGSGQSQSLNVVRRWQSAMQKLPQANMTLISVAGEYAAELAHQALSSEKSVMIFSDNVTLEDEIALK
TRAREKGLLVMGPDCGTAMIAGTPLAFANVTPEGNIGVIGASGTGIQELVSQIALGGEGISHAIGLGGRDLSAEVGGLSA
QTALEMLTQDAQSQVLAFVSKPPDEAVRLKIINAMKRSAKPVVALFLGYVSPVNRDENVWFARTLDEAGRLACLLARVVR
HQENLTAVADKHIRGLYTGGTLAAESAGLLAERLNITPDEHHPQGMMLNALGHQIVDLGDDFYTVGRPHPMIDPSLRNQL
IAELGEQTQVGVLLLDVVIGYGATADPAGSLVEACRLAWALRSESHPLHVIATVTGTENDPQCRSRQIAELEDAGVVVVD
SLPEAALLAVALISPQRMAEPAPRSSLLDGVAVINAGLRSFAIDLQSAGTPVVHYQWAPIAGGNKKLARLLERLQ

Sequences:

>Translated_555_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLETTGFWHDDFATATPNDICVAIRTDCADASVTEM
IIARLDDALSALAQGSGQSQSLNVVRRWQSAMQKLPQANMTLISVAGEYAAELAHQALSSEKSVMIFSDNVTLEDEIALK
TRAREKGLLVMGPDCGTAMIAGTPLAFANVTPEGNIGVIGASGTGIQELVSQIALGGEGISHAIGLGGRDLSAEVGGLSA
QTALEMLTQDAQSQVLAFVSKPPDEAVRLKIINAMKRSAKPVVALFLGYVSPVNRDENVWFARTLDEAGRLACLLARVVR
HQENLTAVADKHIRGLYTGGTLAAESAGLLAERLNITPDEHHPQGMMLNALGHQIVDLGDDFYTVGRPHPMIDPSLRNQL
IAELGEQTQVGVLLLDVVIGYGATADPAGSLVEACRLAWALRSESHPLHVIATVTGTENDPQCRSRQIAELEDAGVVVVD
SLPEAALLAVALISPQRMAEPAPRSSLLDGVAVINAGLRSFAIDLQSAGTPVVHYQWAPIAGGNKKLARLLERLQ
>Mature_555_residues
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLETTGFWHDDFATATPNDICVAIRTDCADASVTEM
IIARLDDALSALAQGSGQSQSLNVVRRWQSAMQKLPQANMTLISVAGEYAAELAHQALSSEKSVMIFSDNVTLEDEIALK
TRAREKGLLVMGPDCGTAMIAGTPLAFANVTPEGNIGVIGASGTGIQELVSQIALGGEGISHAIGLGGRDLSAEVGGLSA
QTALEMLTQDAQSQVLAFVSKPPDEAVRLKIINAMKRSAKPVVALFLGYVSPVNRDENVWFARTLDEAGRLACLLARVVR
HQENLTAVADKHIRGLYTGGTLAAESAGLLAERLNITPDEHHPQGMMLNALGHQIVDLGDDFYTVGRPHPMIDPSLRNQL
IAELGEQTQVGVLLLDVVIGYGATADPAGSLVEACRLAWALRSESHPLHVIATVTGTENDPQCRSRQIAELEDAGVVVVD
SLPEAALLAVALISPQRMAEPAPRSSLLDGVAVINAGLRSFAIDLQSAGTPVVHYQWAPIAGGNKKLARLLERLQ

Specific function: Not known; multicopy suppressor of dominant negative ftsH mutations [H]

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To E.coli yahF and some, to bacterial sucD [H]

Homologues:

Organism=Escherichia coli, GI1786729, Length=555, Percent_Identity=75.1351351351351, Blast_Score=818, Evalue=0.0,
Organism=Escherichia coli, GI1786513, Length=514, Percent_Identity=37.5486381322957, Blast_Score=303, Evalue=1e-83,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003781
- InterPro:   IPR005811
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: NA

Molecular weight: Translated: 58941; Mature: 58941

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLETTGFWHDDFATAT
CCCHHHHCCCCCCCCEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCC
PNDICVAIRTDCADASVTEMIIARLDDALSALAQGSGQSQSLNVVRRWQSAMQKLPQANM
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCE
TLISVAGEYAAELAHQALSSEKSVMIFSDNVTLEDEIALKTRAREKGLLVMGPDCGTAMI
EEEEHHHHHHHHHHHHHHCCCCEEEEEECCCEECHHHHHHHHHHHCCEEEECCCCCCEEE
AGTPLAFANVTPEGNIGVIGASGTGIQELVSQIALGGEGISHAIGLGGRDLSAEVGGLSA
ECCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHCCCHH
QTALEMLTQDAQSQVLAFVSKPPDEAVRLKIINAMKRSAKPVVALFLGYVSPVNRDENVW
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEE
FARTLDEAGRLACLLARVVRHQENLTAVADKHIRGLYTGGTLAAESAGLLAERLNITPDE
EEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHCCCCCCC
HHPQGMMLNALGHQIVDLGDDFYTVGRPHPMIDPSLRNQLIAELGEQTQVGVLLLDVVIG
CCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHC
YGATADPAGSLVEACRLAWALRSESHPLHVIATVTGTENDPQCRSRQIAELEDAGVVVVD
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
SLPEAALLAVALISPQRMAEPAPRSSLLDGVAVINAGLRSFAIDLQSAGTPVVHYQWAPI
CCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEHHCCCCCEEEEEECCC
AGGNKKLARLLERLQ
CCCCHHHHHHHHHCC
>Mature Secondary Structure
MIHAFIKKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKALLETTGFWHDDFATAT
CCCHHHHCCCCCCCCEEEEEEHHHCCCCCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCC
PNDICVAIRTDCADASVTEMIIARLDDALSALAQGSGQSQSLNVVRRWQSAMQKLPQANM
CCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCE
TLISVAGEYAAELAHQALSSEKSVMIFSDNVTLEDEIALKTRAREKGLLVMGPDCGTAMI
EEEEHHHHHHHHHHHHHHCCCCEEEEEECCCEECHHHHHHHHHHHCCEEEECCCCCCEEE
AGTPLAFANVTPEGNIGVIGASGTGIQELVSQIALGGEGISHAIGLGGRDLSAEVGGLSA
ECCCEEEEECCCCCCEEEEECCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCCHHHCCCHH
QTALEMLTQDAQSQVLAFVSKPPDEAVRLKIINAMKRSAKPVVALFLGYVSPVNRDENVW
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCEE
FARTLDEAGRLACLLARVVRHQENLTAVADKHIRGLYTGGTLAAESAGLLAERLNITPDE
EEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHHHHHCCCCCCC
HHPQGMMLNALGHQIVDLGDDFYTVGRPHPMIDPSLRNQLIAELGEQTQVGVLLLDVVIG
CCCCCHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHC
YGATADPAGSLVEACRLAWALRSESHPLHVIATVTGTENDPQCRSRQIAELEDAGVVVVD
CCCCCCCHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEE
SLPEAALLAVALISPQRMAEPAPRSSLLDGVAVINAGLRSFAIDLQSAGTPVVHYQWAPI
CCCHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHHHHEEEHHCCCCCEEEEEECCC
AGGNKKLARLLERLQ
CCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7500942; 9278503; 3309887 [H]