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The map label for this gene is allR

Identifier: 238893467

GI number: 238893467

Start: 1311851

End: 1312669

Strand: Direct

Name: allR

Synonym: KP1_1360

Alternate gene names: 238893467

Gene position: 1311851-1312669 (Clockwise)

Preceding gene: 238893466

Following gene: 238893468

Centisome position: 24.99

GC content: 57.75

Gene sequence:

>819_bases
ATGACAGAAGTGAGAAGGCGTGGAAGGCCTGGCCAGCAGGAGCCTTCCGCGCAAAAAGGCGCACAGGCGCTGGAGAGAGG
GATCGCGATATTGCAATACCTGGAAAAGAGCGGCGGCAGCTCGTCGGTTAGCGATATTTCCCTGAATCTGGACTTACCGT
TATCGACCACCTTTCGCCTGCTAAAAGTGCTGGAAGGCGCGGATTTTGTCTATCAGGACAGCCAGTTAGGTTGGTGGCAT
ATCGGTCTTGGCGCGTTCAATATCGGCTCGGCCTACATCCATAACCGGGACGTTTTATCCGTCGGTGGGCCCTTTATGCG
GCGGCTGATGCTGATGTCGGGGGAGACAGTCAACGTGGCGATTCGCAATGGCAACGAAGCGGTACTGATTGGCCAGCAGG
AGTGCAAGTCGATGGTGCGAATGTGCGCGCCGCTCGGCAGTCGACTCCCGCTCCATGCTTCAGGCGCCGGGAAAGCGCTG
TTGTATCCGCTGCCTGCGGAAGAGTTGGTGGATGTGATTGTGAAGACCGGCCTGCAGCGGTTTACGCCGACGACGATTGT
GGATTTGCCGGTCCTGCAGCGAAATCTGGATGAGGCGCGAGCCTGCGGCTACAGCATTGACCAGGAGGAGCATGTGACAG
GATTAAACTGTATTGCTTCAGCGGTTTACGATGATGTGGGCTCCGTGGTAGCGGCCATTTCGATTTCCGGACCTGCGTCC
AGGCTAACCCCGGACCGTTTTGTCAGCCAGGGCGAGCTGGTAAGGGAGACGGCAAGGAATATCAGTACCGCGCTGGGCCT
TAAACCCCAGGCCGACTGA

Upstream 100 bases:

>100_bases
TTTGCGTGAGGTTACACGTGACGCTGTCGATTATCTTGCATAACATGTGGGCGCTTACACACTATTTATGCTCAGGTTTT
GAGCCGGAGATAATCGAGGT

Downstream 100 bases:

>100_bases
TCGCCGATCCAACCCGCTCACTTGAGCGGGACTTTTTTGATTATGTTTATATTTGGAAAAATTTTCCAATAAAGTGAGGT
TGTAAAAATGGCAAAAATGA

Product: DNA-binding transcriptional repressor AllR

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons

Number of amino acids: Translated: 272; Mature: 271

Protein sequence:

>272_residues
MTEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLEGADFVYQDSQLGWWH
IGLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVAIRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLPAEELVDVIVKTGLQRFTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPAS
RLTPDRFVSQGELVRETARNISTALGLKPQAD

Sequences:

>Translated_272_residues
MTEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLEGADFVYQDSQLGWWH
IGLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVAIRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKAL
LYPLPAEELVDVIVKTGLQRFTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPAS
RLTPDRFVSQGELVRETARNISTALGLKPQAD
>Mature_271_residues
TEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRLLKVLEGADFVYQDSQLGWWHI
GLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVAIRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKALL
YPLPAEELVDVIVKTGLQRFTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPASR
LTPDRFVSQGELVRETARNISTALGLKPQAD

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain

Homologues:

Organism=Escherichia coli, GI1786715, Length=268, Percent_Identity=86.1940298507463, Blast_Score=485, Evalue=1e-138,
Organism=Escherichia coli, GI87082359, Length=264, Percent_Identity=40.530303030303, Blast_Score=210, Evalue=8e-56,
Organism=Escherichia coli, GI1788131, Length=224, Percent_Identity=28.5714285714286, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1786468, Length=245, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=8e-25,
Organism=Escherichia coli, GI1789999, Length=267, Percent_Identity=29.5880149812734, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790752, Length=256, Percent_Identity=26.5625, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1788581, Length=251, Percent_Identity=27.8884462151394, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALLR_KLEPN (Q765S0)

Other databases:

- EMBL:   AB115590
- HSSP:   P16528
- ProteinModelPortal:   Q765S0
- SMR:   Q765S0
- GO:   GO:0006350
- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- SMART:   SM00346

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR

EC number: NA

Molecular weight: Translated: 29287; Mature: 29156

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51077 HTH_ICLR; PS51078 ICLR_ED

Important sites: BINDING 207-207 BINDING 217-217

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHH
LKVLEGADFVYQDSQLGWWHIGLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVA
HHHHCCCCEEEECCCCCEEEEECCEEECCCCEEECCCEEECCCHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKALLYPLPAEELVDVIVKTGLQR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHH
FTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPAS
CCCCCEEECHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
RLTPDRFVSQGELVRETARNISTALGLKPQAD
HCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TEVRRRGRPGQQEPSAQKGAQALERGIAILQYLEKSGGSSSVSDISLNLDLPLSTTFRL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCHHHHHHH
LKVLEGADFVYQDSQLGWWHIGLGAFNIGSAYIHNRDVLSVGGPFMRRLMLMSGETVNVA
HHHHCCCCEEEECCCCCEEEEECCEEECCCCEEECCCEEECCCHHHHHHHHHCCCEEEEE
IRNGNEAVLIGQQECKSMVRMCAPLGSRLPLHASGAGKALLYPLPAEELVDVIVKTGLQR
EECCCEEEEEEHHHHHHHHHHHHCCCCCCCEEECCCCCEEEEECCHHHHHHHHHHHHHHH
FTPTTIVDLPVLQRNLDEARACGYSIDQEEHVTGLNCIASAVYDDVGSVVAAISISGPAS
CCCCCEEECHHHHHCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
RLTPDRFVSQGELVRETARNISTALGLKPQAD
HCCHHHHHHCHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA