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The map label for this gene is fkpA [H]

Identifier: 238893107

GI number: 238893107

Start: 937673

End: 939700

Strand: Reverse

Name: fkpA [H]

Synonym: KP1_0953

Alternate gene names: 238893107

Gene position: 939700-937673 (Counterclockwise)

Preceding gene: 238893108

Following gene: 238893106

Centisome position: 17.9

GC content: 55.67

Gene sequence:

>2028_bases
ATGAACAGAGCCGCCACGCTGACCCTCAACGCGCCCCTGCTGATGCTCGTCGCTGCGCTGGCGCTTTCAACCCCTTTCAC
CGCCGGCGCCGCGCCGGCCTTTCTTGATTACGCCCAACAGCAAACCCAGCAATCTCAGGCGCAAGAAAAAAACGATGCCG
CAAGCGCAAAACAAACACAAGAAAGCCGCCAGAGCGCAGATAATAAAAAAACCGGTACCAGCACCTCACAATTACAAAAA
AGAATCACCAGCCAGCAGGCGGCGATTGCACAAAAAGATAAGCTTATACAGCAATTAAAAAAACAGCTTGCCGCTACGCC
GCAAACGGATACTGCCGGAGCGAATGAGCAAGCGGCGTTGAATAAGAGAATTAATGAATTACAGGTCGCCTTAAGCGCCG
CTACTGCAGAAAAAGAGGCATTAATAAAAAAAGCAGGCGTTGTGCAGAATAATAATCTACAGCAAAGCCAGGCCGCGGCG
CGTCAGCAGATCCAGCAATTAACGACGCAGATTCAGCAAGCCGAAGCTGAAAATAAACGCCTCAGCGCCAGCTTTACCAC
GCTTAATAAAGATAAACACGCGCTAATGACCCAACTGGCCGCAACGGAAAAAGAGAAACAGGCCGCTCTTGAGCAGGTCA
AAGCGCTTAACGCTGACAAACAGCCGCTGACGACCCGGCTGGCCGCCGCGGAAAAAGAGAAACAGGCCGTCCTCGAGCAG
GTTAAGGCCCTTAACGCCGATAAACAGTCGCTGACTATTCGCCTCGCCGCTGCGGAGAAAGCGCAGCAGGCCGCTGTTGA
CCAGGCTAAAGCGCTTAACGCTGACAAACAGCCGCTGGCTACCCGACTGGCCGCCGCGGAAAAAGAGAAACAGGCCGTCC
TCGAGCAGGTTAAGGCCCTTAGCGCCGATAAGCAGTCGCTGACTATTCGCCTCGCCGCTGCGGAGAAGGCGCAGCAGGCC
GCTCTTGACCAGGCTAAAGCGCTTAACGCTGACAAACAGCCGCTGGCGACCCGGCTGGCCGCCGCGGAAAAAGAGAAACA
GGCCGTCCTCGAGCAGGTTAAAGCCCTTAACGCCGATAAGCAGTCGCTGACTATTCGCCTCGCCGCTGCGGAAAAGACGC
AGCAGGCTGCCCTCGATCAGGTCAAAGCCCTTAACGCCGATAAACAATCGCTGTCCACCCGGCTGGCCGCCGCGGATAAA
GCGCCGCATGGCCCCGCTAACGACGCCGCTGCGCCAAAAAATGAGCCACCAGAGATGGCGGCCATAGTGGCAGCCTATCG
CCTGCAGGCGGATAAAGACAACGCCCAGCTACGGATGAAAGAAGATGAAATCGAACTGCTGAGAACGCAGCTTTCTGTAC
AGTCCAAAACGCGCAGCGGCGAGAGCGCCGCCGCCAAACTCAGCGCATCGGGAGAACAGCAGGCTTATGCGATCGGCGCC
TCGATGGGAAGCGAGGCGCTCAACGTCCTTACCACCCGTCGTACTCAGGGAGTTACCGTCGACGCAGGCCTGGTGCTGCA
GGGCATCGAAGATGCCTTTCGCGGCCAGCTTCGTCTCGGAGAGCAGGAACGTAACAAGGCGCTGTTTGATGTGTCGCAGC
AGGTTTTTCAGAACCTGAATAAAATAGAGCAGAAAAACATCAGTGCCGGCAAGAAATATCAGCAGGCGTTTGCGCGCAAA
AAAGATGTGGTCTTTAAAGAGGGCGTCTACAGCCGCGTCGATTACCTGGGTAAAGGAAAAATAAGCGGTAATGACCTGGT
TACCGTGGTGATCAAAGAGATGCTGACGGACGGGACGGTGATCAACGATATGGAAGCGAAAGATCAGGCGCTTACGCAAA
AGCTGGATGCCTATCCCCCGGTGTTTCGCGAACCGCTGAAGCGTCTACAGAACCACGGCTCCGTGACGCTCGTCGTCCCG
CCTGAAAAGGCCTATGGCAGTAAAGGATTACCGCCAAAAATCCCGCCAGGCGCCACCATGGTTTATTCCGTGCGGATAGT
AGATAGCCAACCCGAGCCGGCAAAATAG

Upstream 100 bases:

>100_bases
GCATTGACTCCATGTATCAGTTTAAATCCATCAAACTGTGCGCCGATATCCAGAAAACGCTGATCGATAGCCTGGTACAG
CGTGGTGAAAGCAAACAGCC

Downstream 100 bases:

>100_bases
CCTCATCCTCTCCACCGCCCTTCCGGGGCGGTGGCTGTTATTCCTGCCTCATTGCTGCAATAACCGCCGTGCATCCTCAT
CTATAGTTGTCTATGATGTT

Product: hypothetical protein

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MNRAATLTLNAPLLMLVAALALSTPFTAGAAPAFLDYAQQQTQQSQAQEKNDAASAKQTQESRQSADNKKTGTSTSQLQK
RITSQQAAIAQKDKLIQQLKKQLAATPQTDTAGANEQAALNKRINELQVALSAATAEKEALIKKAGVVQNNNLQQSQAAA
RQQIQQLTTQIQQAEAENKRLSASFTTLNKDKHALMTQLAATEKEKQAALEQVKALNADKQPLTTRLAAAEKEKQAVLEQ
VKALNADKQSLTIRLAAAEKAQQAAVDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALSADKQSLTIRLAAAEKAQQA
ALDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALNADKQSLTIRLAAAEKTQQAALDQVKALNADKQSLSTRLAAADK
APHGPANDAAAPKNEPPEMAAIVAAYRLQADKDNAQLRMKEDEIELLRTQLSVQSKTRSGESAAAKLSASGEQQAYAIGA
SMGSEALNVLTTRRTQGVTVDAGLVLQGIEDAFRGQLRLGEQERNKALFDVSQQVFQNLNKIEQKNISAGKKYQQAFARK
KDVVFKEGVYSRVDYLGKGKISGNDLVTVVIKEMLTDGTVINDMEAKDQALTQKLDAYPPVFREPLKRLQNHGSVTLVVP
PEKAYGSKGLPPKIPPGATMVYSVRIVDSQPEPAK

Sequences:

>Translated_675_residues
MNRAATLTLNAPLLMLVAALALSTPFTAGAAPAFLDYAQQQTQQSQAQEKNDAASAKQTQESRQSADNKKTGTSTSQLQK
RITSQQAAIAQKDKLIQQLKKQLAATPQTDTAGANEQAALNKRINELQVALSAATAEKEALIKKAGVVQNNNLQQSQAAA
RQQIQQLTTQIQQAEAENKRLSASFTTLNKDKHALMTQLAATEKEKQAALEQVKALNADKQPLTTRLAAAEKEKQAVLEQ
VKALNADKQSLTIRLAAAEKAQQAAVDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALSADKQSLTIRLAAAEKAQQA
ALDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALNADKQSLTIRLAAAEKTQQAALDQVKALNADKQSLSTRLAAADK
APHGPANDAAAPKNEPPEMAAIVAAYRLQADKDNAQLRMKEDEIELLRTQLSVQSKTRSGESAAAKLSASGEQQAYAIGA
SMGSEALNVLTTRRTQGVTVDAGLVLQGIEDAFRGQLRLGEQERNKALFDVSQQVFQNLNKIEQKNISAGKKYQQAFARK
KDVVFKEGVYSRVDYLGKGKISGNDLVTVVIKEMLTDGTVINDMEAKDQALTQKLDAYPPVFREPLKRLQNHGSVTLVVP
PEKAYGSKGLPPKIPPGATMVYSVRIVDSQPEPAK
>Mature_675_residues
MNRAATLTLNAPLLMLVAALALSTPFTAGAAPAFLDYAQQQTQQSQAQEKNDAASAKQTQESRQSADNKKTGTSTSQLQK
RITSQQAAIAQKDKLIQQLKKQLAATPQTDTAGANEQAALNKRINELQVALSAATAEKEALIKKAGVVQNNNLQQSQAAA
RQQIQQLTTQIQQAEAENKRLSASFTTLNKDKHALMTQLAATEKEKQAALEQVKALNADKQPLTTRLAAAEKEKQAVLEQ
VKALNADKQSLTIRLAAAEKAQQAAVDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALSADKQSLTIRLAAAEKAQQA
ALDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALNADKQSLTIRLAAAEKTQQAALDQVKALNADKQSLSTRLAAADK
APHGPANDAAAPKNEPPEMAAIVAAYRLQADKDNAQLRMKEDEIELLRTQLSVQSKTRSGESAAAKLSASGEQQAYAIGA
SMGSEALNVLTTRRTQGVTVDAGLVLQGIEDAFRGQLRLGEQERNKALFDVSQQVFQNLNKIEQKNISAGKKYQQAFARK
KDVVFKEGVYSRVDYLGKGKISGNDLVTVVIKEMLTDGTVINDMEAKDQALTQKLDAYPPVFREPLKRLQNHGSVTLVVP
PEKAYGSKGLPPKIPPGATMVYSVRIVDSQPEPAK

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789745, Length=213, Percent_Identity=32.3943661971831, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 72648; Mature: 72648

Theoretical pI: Translated: 10.19; Mature: 10.19

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRAATLTLNAPLLMLVAALALSTPFTAGAAPAFLDYAQQQTQQSQAQEKNDAASAKQTQ
CCCCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESRQSADNKKTGTSTSQLQKRITSQQAAIAQKDKLIQQLKKQLAATPQTDTAGANEQAAL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
NKRINELQVALSAATAEKEALIKKAGVVQNNNLQQSQAAARQQIQQLTTQIQQAEAENKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSASFTTLNKDKHALMTQLAATEKEKQAALEQVKALNADKQPLTTRLAAAEKEKQAVLEQ
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VKALNADKQSLTIRLAAAEKAQQAAVDQAKALNADKQPLATRLAAAEKEKQAVLEQVKAL
HHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SADKQSLTIRLAAAEKAQQAALDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALNADK
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QSLTIRLAAAEKTQQAALDQVKALNADKQSLSTRLAAADKAPHGPANDAAAPKNEPPEMA
HHEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
AIVAAYRLQADKDNAQLRMKEDEIELLRTQLSVQSKTRSGESAAAKLSASGEQQAYAIGA
HHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHEEHHH
SMGSEALNVLTTRRTQGVTVDAGLVLQGIEDAFRGQLRLGEQERNKALFDVSQQVFQNLN
HHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHH
KIEQKNISAGKKYQQAFARKKDVVFKEGVYSRVDYLGKGKISGNDLVTVVIKEMLTDGTV
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
INDMEAKDQALTQKLDAYPPVFREPLKRLQNHGSVTLVVPPEKAYGSKGLPPKIPPGATM
ECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCCCCCEE
VYSVRIVDSQPEPAK
EEEEEEECCCCCCCC
>Mature Secondary Structure
MNRAATLTLNAPLLMLVAALALSTPFTAGAAPAFLDYAQQQTQQSQAQEKNDAASAKQTQ
CCCCEEEEECCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESRQSADNKKTGTSTSQLQKRITSQQAAIAQKDKLIQQLKKQLAATPQTDTAGANEQAAL
HHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHH
NKRINELQVALSAATAEKEALIKKAGVVQNNNLQQSQAAARQQIQQLTTQIQQAEAENKR
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSASFTTLNKDKHALMTQLAATEKEKQAALEQVKALNADKQPLTTRLAAAEKEKQAVLEQ
EEHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
VKALNADKQSLTIRLAAAEKAQQAAVDQAKALNADKQPLATRLAAAEKEKQAVLEQVKAL
HHHHCCCCHHEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SADKQSLTIRLAAAEKAQQAALDQAKALNADKQPLATRLAAAEKEKQAVLEQVKALNADK
CCCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
QSLTIRLAAAEKTQQAALDQVKALNADKQSLSTRLAAADKAPHGPANDAAAPKNEPPEMA
HHEEEEEECHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
AIVAAYRLQADKDNAQLRMKEDEIELLRTQLSVQSKTRSGESAAAKLSASGEQQAYAIGA
HHHHHHHHHCCCCCCCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCHHEEHHH
SMGSEALNVLTTRRTQGVTVDAGLVLQGIEDAFRGQLRLGEQERNKALFDVSQQVFQNLN
HHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHHHHHHH
KIEQKNISAGKKYQQAFARKKDVVFKEGVYSRVDYLGKGKISGNDLVTVVIKEMLTDGTV
HHHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
INDMEAKDQALTQKLDAYPPVFREPLKRLQNHGSVTLVVPPEKAYGSKGLPPKIPPGATM
ECCCHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEEECCHHHCCCCCCCCCCCCCCEE
VYSVRIVDSQPEPAK
EEEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]