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The map label for this gene is sms [H]

Identifier: 238892975

GI number: 238892975

Start: 782122

End: 783504

Strand: Direct

Name: sms [H]

Synonym: KP1_0805

Alternate gene names: 238892975

Gene position: 782122-783504 (Clockwise)

Preceding gene: 238892974

Following gene: 238892976

Centisome position: 14.9

GC content: 62.26

Gene sequence:

>1383_bases
GTGGCGAAAGCTCCAAAACGCGCATTTGTCTGTAATGAATGTGGTGCGGATTATCCGCGCTGGCAGGGGCAGTGCAGCGC
CTGCCATGCCTGGAACACCATCACCGAGATGCGCATCGCCGCGTCGCCGCAGGTGGCGAGAAACGAGCGTCTTTCAGGCT
ATGCCGGTAACGCCGGCGTGTCGAAGGTGCAGAAGCTGTCAGATATCAGCCTGGAGGCGCTGCCGCGTTTCTCCACCGGC
TTTAAAGAATTTGACCGCGTGCTGGGCGGCGGCGTGGTACCGGGCAGCGCGATCCTGATTGGCGGCAACCCCGGCGCGGG
CAAATCGACGCTGCTGCTGCAAACCCTCTGCAAACTGGCGGAAGGGATGAAAACCCTGTACGTCACCGGGGAGGAGTCCC
TGCAGCAGGTGGCGATGCGCGCCCATCGTCTCGGGTTGCCAACGGCCAACCTGAACATGCTCTCGGAAACCAGCATTGAG
CAGATCTGTCAGATCGCCGATGAAGAAAAGCCGCAGCTGATGGTGATCGACTCCATCCAGGTGATGCATATGGCCGACGT
ACAGTCGTCGCCGGGCAGCGTCGCCCAGGTACGGGAAACCGCGGCCTATTTGACGCGCTTTGCTAAAACTCGCGGCGTGG
CGATTGTGATGGTCGGCCACGTCACCAAAGACGGCTCGCTGGCCGGTCCGAAGGTGCTGGAGCACTGTATCGACTGCTCG
GTGCTGCTGGACGGGGATGCCGACTCCCGCTTCCGCACGTTGCGCAGCCATAAAAACCGCTTTGGCGCGGTGAACGAGCT
GGGCGTCTTCGCCATGACCGAGCAGGGCCTGCGTGAAGTGAGCAACCCGTCCGCTATCTTCCTCAGCCGGGGAGATGAAA
TCACCTCCGGTAGCTCGGTGATGGTGGTCTGGGAAGGGACCCGCCCGCTGCTGGTGGAGATCCAGGCGCTGGTCGATCAC
TCAATGATGTCCAACCCGCGCCGCGTTGCGGTGGGGCTGGAACAGAACCGTCTGGCGATCCTGCTGGCGGTGCTGCACCG
TCACGGCGGCCTACAGATGGCCGATCAGGACGTCTTCGTCAATGTGGTCGGCGGGGTGAAGGTCACGGAAACCAGCGCCG
ACCTGGCGCTGCTGCTGGCGATGGTCTCCAGCCTGCGCGACCGTCCTCTGCCGCAGGATCTGGTGGTCTTTGGCGAAGTG
GGGCTGGCCGGGGAAATTCGCCCGGTACCGAGCGGTCAGGAGCGTATCTCCGAAGCGGCGAAGCACGGCTTCCGTCGCGC
CATCGTCCCGGCGGCCAATGTGCCGAAAAAAGTGCCGGAAGGCATGCAAATCTTTGGCGTGAAAAAGCTTTCAGACGCGC
TAAGCGTTTTTGACGACTTATAA

Upstream 100 bases:

>100_bases
CAAAGTGAATGAACAGGCGGAAGTGACTATCCGCCACGCTGACCTGATGGGGGTATTCTGTATCCTCTCGGGCAGCATGA
ACCAAAAGTAAGAGGTAAAC

Downstream 100 bases:

>100_bases
TAAGTTAAAAGGAGATTAGCGATGTCGTCATTTGACTATTTAAAAAGCGCCATTAAGCAGAAAGGCTGTACCCTGCAGCA
GGTGGCGGAAGCCAGCGGAA

Product: DNA repair protein RadA

Products: NA

Alternate protein names: DNA repair protein sms [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEMRIAASPQVARNERLSGYAGNAGVSKVQKLSDISLEALPRFSTG
FKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLAEGMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIE
QICQIADEEKPQLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCS
VLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEITSGSSVMVVWEGTRPLLVEIQALVDH
SMMSNPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEV
GLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKVPEGMQIFGVKKLSDALSVFDDL

Sequences:

>Translated_460_residues
MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEMRIAASPQVARNERLSGYAGNAGVSKVQKLSDISLEALPRFSTG
FKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLAEGMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIE
QICQIADEEKPQLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCS
VLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEITSGSSVMVVWEGTRPLLVEIQALVDH
SMMSNPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEV
GLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKVPEGMQIFGVKKLSDALSVFDDL
>Mature_459_residues
AKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEMRIAASPQVARNERLSGYAGNAGVSKVQKLSDISLEALPRFSTGF
KEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLAEGMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIEQ
ICQIADEEKPQLMVIDSIQVMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCSV
LLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEITSGSSVMVVWEGTRPLLVEIQALVDHS
MMSNPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEVG
LAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKVPEGMQIFGVKKLSDALSVFDDL

Specific function: May play a role in the repair of endogenous alkylation damage [H]

COG id: COG1066

COG function: function code O; Predicted ATP-dependent serine protease

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recA family. RadA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790850, Length=460, Percent_Identity=96.5217391304348, Blast_Score=914, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR014774
- InterPro:   IPR004504
- InterPro:   IPR008269
- InterPro:   IPR020568 [H]

Pfam domain/function: PF06745 KaiC; PF05362 Lon_C [H]

EC number: NA

Molecular weight: Translated: 49432; Mature: 49301

Theoretical pI: Translated: 7.53; Mature: 7.53

Prosite motif: PS50162 RECA_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEMRIAASPQVARNERLSGYAGNAGV
CCCCCCCCEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHH
SKVQKLSDISLEALPRFSTGFKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLA
HHHHHHHCCCHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
EGMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIEQICQIADEEKPQLMVIDSIQ
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEE
VMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCS
EEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHCCCE
VLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEITSGSSV
EEEECCCCHHHHHHHHHHHHCCCHHHCCHHEECHHHHHHHCCCCEEEEECCCCCCCCCEE
MVVWEGTRPLLVEIQALVDHSMMSNPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFV
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECCCEEE
NVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEVGLAGEIRPVPSGQERISEAA
EEECCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHH
KHGFRRAIVPAANVPKKVPEGMQIFGVKKLSDALSVFDDL
HHCHHEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCC
>Mature Secondary Structure 
AKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEMRIAASPQVARNERLSGYAGNAGV
CCCCCCCEEEHHCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHH
SKVQKLSDISLEALPRFSTGFKEFDRVLGGGVVPGSAILIGGNPGAGKSTLLLQTLCKLA
HHHHHHHCCCHHHCCCCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHH
EGMKTLYVTGEESLQQVAMRAHRLGLPTANLNMLSETSIEQICQIADEEKPQLMVIDSIQ
CCCEEEEEECHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCEEEECCEE
VMHMADVQSSPGSVAQVRETAAYLTRFAKTRGVAIVMVGHVTKDGSLAGPKVLEHCIDCS
EEEEHHCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEEEECCCCCCCCHHHHHHHCCCE
VLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQGLREVSNPSAIFLSRGDEITSGSSV
EEEECCCCHHHHHHHHHHHHCCCHHHCCHHEECHHHHHHHCCCCEEEEECCCCCCCCCEE
MVVWEGTRPLLVEIQALVDHSMMSNPRRVAVGLEQNRLAILLAVLHRHGGLQMADQDVFV
EEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCCEEECCCEEE
NVVGGVKVTETSADLALLLAMVSSLRDRPLPQDLVVFGEVGLAGEIRPVPSGQERISEAA
EEECCEEEECCHHHHHHHHHHHHHHHCCCCCCHHEEEECCCCCCCCCCCCCHHHHHHHHH
KHGFRRAIVPAANVPKKVPEGMQIFGVKKLSDALSVFDDL
HHCHHEEECCCCCCCCCCCCCCEEEEHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1327967; 8759876; 7610040; 9278503 [H]