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The map label for this gene is serB [H]

Identifier: 238892974

GI number: 238892974

Start: 781120

End: 782112

Strand: Direct

Name: serB [H]

Synonym: KP1_0804

Alternate gene names: 238892974

Gene position: 781120-782112 (Clockwise)

Preceding gene: 238892971

Following gene: 238892975

Centisome position: 14.88

GC content: 61.03

Gene sequence:

>993_bases
ATGAAGAGATGTGGAGCCGTAATGCCTAACAGTTTGACCTGGTGCGACCTGCCTGAAGACGTTTCCCTGTGGCCTGGGTT
GCCGCTTTCCCTGAGCGGCGACGAGGTCATGCCGCTGGATTATCACGCCGGGCGCAGCGGCTGGCTGCTGTATGGTCGCG
GTCTGGATAAACGTCGGCTGACGGCGTGGCAGCGTGAGCTGGGCGCCGCGTTAGTGATCGTTGCCTCCTGGGTGGTCGAG
GATTACCAGGTGATCCGTCTGGCCGGTTCGCTGACTCCCCGTGCGACGCGACTGGCGCATGAGGCGGGGCTGGACGTCGC
GCCATTGGGTAAAATTCCCCATTTGCGCACCCCGGGCCTGCTGGTGATGGACATGGACTCCACGGCGATTCAGATCGAAT
GCATCGATGAGATCGCGAAACTGGCCGGCACCGGCGAGCTGGTCTCGGAAGTGACCGAGCGGGCGATGCGTGGCGAGCTG
GACTTCACCGCCAGCCTGCGCCAGCGCGTGGCGACGCTGAAAGACGCCGATGCCAGTATTTTGCTGCAGGTTCGCGACGC
GCTGCCGCTGATGCCGGGCCTGGCGCAGCTGGTGCTCAAGCTGGAAACGCTGGGCTGGAAAGTGGCGATCGCCTCCGGCG
GTTTCACCTTCTTTGCCGAATATCTGCGCGACAAACTGCATCTCGACGCGGTATTCGCCAATGAGCTGGAGATCCGCGAC
GGCAAGCTCACCGGCAACGTGCTCGGCGATATCGTCGATGCGAAATATAAAGCCAATACGTTGCGCAAGCTGGCGGAAAA
GTATGAGATCCCAACGGCGCAAACCGTGGCTATCGGCGATGGCGCCAACGACCTGCCGATGATTAAGGCAGCAGGGCTTG
GCATCGCCTATCACGCGAAGCCCAAAGTGAATGAACAGGCGGAAGTGACTATCCGCCACGCTGACCTGATGGGGGTATTC
TGTATCCTCTCGGGCAGCATGAACCAAAAGTAA

Upstream 100 bases:

>100_bases
AGTTTTGCGCGAACCATATTCCACCTTTGAAAATTTGCAGCTTAATGTTGCCAGAAGCGCTGGTTACAAGGTAGCCTCAT
GCGTTATTTTCCTCGCCTGA

Downstream 100 bases:

>100_bases
GAGGTAAACGTGGCGAAAGCTCCAAAACGCGCATTTGTCTGTAATGAATGTGGTGCGGATTATCCGCGCTGGCAGGGGCA
GTGCAGCGCCTGCCATGCCT

Product: phosphoserine phosphatase

Products: NA

Alternate protein names: PSP; PSPase; O-phosphoserine phosphohydrolase [H]

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKRCGAVMPNSLTWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKRRLTAWQRELGAALVIVASWVVE
DYQVIRLAGSLTPRATRLAHEAGLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGELVSEVTERAMRGEL
DFTASLRQRVATLKDADASILLQVRDALPLMPGLAQLVLKLETLGWKVAIASGGFTFFAEYLRDKLHLDAVFANELEIRD
GKLTGNVLGDIVDAKYKANTLRKLAEKYEIPTAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEQAEVTIRHADLMGVF
CILSGSMNQK

Sequences:

>Translated_330_residues
MKRCGAVMPNSLTWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKRRLTAWQRELGAALVIVASWVVE
DYQVIRLAGSLTPRATRLAHEAGLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGELVSEVTERAMRGEL
DFTASLRQRVATLKDADASILLQVRDALPLMPGLAQLVLKLETLGWKVAIASGGFTFFAEYLRDKLHLDAVFANELEIRD
GKLTGNVLGDIVDAKYKANTLRKLAEKYEIPTAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEQAEVTIRHADLMGVF
CILSGSMNQK
>Mature_330_residues
MKRCGAVMPNSLTWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKRRLTAWQRELGAALVIVASWVVE
DYQVIRLAGSLTPRATRLAHEAGLDVAPLGKIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGELVSEVTERAMRGEL
DFTASLRQRVATLKDADASILLQVRDALPLMPGLAQLVLKLETLGWKVAIASGGFTFFAEYLRDKLHLDAVFANELEIRD
GKLTGNVLGDIVDAKYKANTLRKLAEKYEIPTAQTVAIGDGANDLPMIKAAGLGIAYHAKPKVNEQAEVTIRHADLMGVF
CILSGSMNQK

Specific function: Unknown

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI46249388, Length=182, Percent_Identity=32.967032967033, Blast_Score=87, Evalue=2e-17,
Organism=Escherichia coli, GI1790849, Length=323, Percent_Identity=88.8544891640867, Blast_Score=584, Evalue=1e-168,
Organism=Saccharomyces cerevisiae, GI6321647, Length=247, Percent_Identity=38.8663967611336, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR023190
- InterPro:   IPR004469 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.3 [H]

Molecular weight: Translated: 35910; Mature: 35910

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRCGAVMPNSLTWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKRRL
CCCCCCCCCCCCEECCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCCCHHHH
TAWQRELGAALVIVASWVVEDYQVIRLAGSLTPRATRLAHEAGLDVAPLGKIPHLRTPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LVMDMDSTAIQIECIDEIAKLAGTGELVSEVTERAMRGELDFTASLRQRVATLKDADASI
EEEECCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHE
LLQVRDALPLMPGLAQLVLKLETLGWKVAIASGGFTFFAEYLRDKLHLDAVFANELEIRD
EEEEHHHCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCEEEEC
GKLTGNVLGDIVDAKYKANTLRKLAEKYEIPTAQTVAIGDGANDLPMIKAAGLGIAYHAK
CCEEHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEECC
PKVNEQAEVTIRHADLMGVFCILSGSMNQK
CCCCCCEEEEEEHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKRCGAVMPNSLTWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYGRGLDKRRL
CCCCCCCCCCCCEECCCCCCCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCCCHHHH
TAWQRELGAALVIVASWVVEDYQVIRLAGSLTPRATRLAHEAGLDVAPLGKIPHLRTPGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCE
LVMDMDSTAIQIECIDEIAKLAGTGELVSEVTERAMRGELDFTASLRQRVATLKDADASI
EEEECCCCEEEEEEHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHE
LLQVRDALPLMPGLAQLVLKLETLGWKVAIASGGFTFFAEYLRDKLHLDAVFANELEIRD
EEEEHHHCCCCHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHEEEEECCEEEEC
GKLTGNVLGDIVDAKYKANTLRKLAEKYEIPTAQTVAIGDGANDLPMIKAAGLGIAYHAK
CCEEHHHHHHHHHCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEEEECCCEEEEECC
PKVNEQAEVTIRHADLMGVFCILSGSMNQK
CCCCCCEEEEEEHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]