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The map label for this gene is hpaR [H]

Identifier: 238892922

GI number: 238892922

Start: 731286

End: 731726

Strand: Direct

Name: hpaR [H]

Synonym: KP1_0745

Alternate gene names: 238892922

Gene position: 731286-731726 (Clockwise)

Preceding gene: 238892921

Following gene: 238892923

Centisome position: 13.93

GC content: 58.5

Gene sequence:

>441_bases
ATGCATGATTCATTAACCATTGCCTTGTTGCAGGCGCGTGAAGCGGCGATGGCCTACTTTCGACCGATCGTCAAACGGCA
CAATCTCACCGAACAGCAGTGGCGGATCGTGCGAATTCTCGCCGAACGTCCGTCGATGGACTTTCACGATCTGGCCTTTC
GCGCCTGTATCCTGCGCCCCAGTCTGACCGGTATTTTGACGCGCATGGAGCGGGATGGGCTGGTGCTGCGCTTAAAGCCA
GTTAACGATCAGCGCAAGCTGTACGTTTCGCTGACGCCTGCCGGTACCGCGCTGTACGAAAGCGCTCAGGCGGAGGTGGA
AGAAACCTATCGCCTGCTGGAGGCCCAGTTCACCACGGAAAAGCTGCAGCAACTGACCTCGCTGCTGGAGGAGTTTATTG
CGCTTGGCGTCCCTGCCGGGCGCGGCGATGAAGAAGAGTAG

Upstream 100 bases:

>100_bases
ACTGGTACTTTTCAGGTGCAGAAACCGGTTGTACATGGCAGGATTAACGCTAATTATTAAGTTATTAATAAGTTTTTGGT
GAGGCTGTTGAGGGGATACT

Downstream 100 bases:

>100_bases
CGGTTACGGCTCGGCGCTCAGCCTGGCGAGGGCAATAAGCGTTTCCGCGCGGGCGGGGGACAGCGGCTCTCTCGGCTGCG
GCAGCGGCCAGCCATACAGC

Product: homoprotocatechuate degradative operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 146

Protein sequence:

>146_residues
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRPSLTGILTRMERDGLVLRLKP
VNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTEKLQQLTSLLEEFIALGVPAGRGDEEE

Sequences:

>Translated_146_residues
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRPSLTGILTRMERDGLVLRLKP
VNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTEKLQQLTSLLEEFIALGVPAGRGDEEE
>Mature_146_residues
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRPSLTGILTRMERDGLVLRLKP
VNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTEKLQQLTSLLEEFIALGVPAGRGDEEE

Specific function: Repressor for the homoprotocatechuate catabolic pathway hpc operon [H]

COG id: COG1846

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH marR-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012712
- InterPro:   IPR000835
- InterPro:   IPR023187
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01047 MarR [H]

EC number: NA

Molecular weight: Translated: 16713; Mature: 16713

Theoretical pI: Translated: 5.73; Mature: 5.73

Prosite motif: PS01117 HTH_MARR_1 ; PS50995 HTH_MARR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SLTGILTRMERDGLVLRLKPVNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLQQLTSLLEEFIALGVPAGRGDEEE
HHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MHDSLTIALLQAREAAMAYFRPIVKRHNLTEQQWRIVRILAERPSMDFHDLAFRACILRP
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHCC
SLTGILTRMERDGLVLRLKPVNDQRKLYVSLTPAGTALYESAQAEVEETYRLLEAQFTTE
HHHHHHHHHCCCCEEEEEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLQQLTSLLEEFIALGVPAGRGDEEE
HHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384293; 8550403 [H]