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The map label for this gene is hpaX [H]

Identifier: 238892913

GI number: 238892913

Start: 723793

End: 725163

Strand: Reverse

Name: hpaX [H]

Synonym: KP1_0736

Alternate gene names: 238892913

Gene position: 725163-723793 (Counterclockwise)

Preceding gene: 238892914

Following gene: 238892912

Centisome position: 13.82

GC content: 59.37

Gene sequence:

>1371_bases
GTGGAGCGCAACATGACTACCTCTACCCTGCAACACAATGATAATAAAGCCGTTGAAGTAGAAAACCGGGTGATCAAAAA
GCTGTTCCGCCGCCTGATTACCTTCCTGTTTGTTCTCTTTGTTTTCTCATTTTTGGATCGAATTAATATCGGCTTCGCCG
GTCTGACGATGGGTAAAGATCTCGGCCTGACCTCCACCATGTTCGGCCTGGCGGCGACGCTGTTCTACGTCACCTACGTG
CTGTGCGGGATCCCCAGCAATATCATGCTGGCGAAAGTCGGCGCGCGCCGTTGGATCGCCGGGATCATGGTGGTCTGGGG
GATCGCCTCGACCTGCACCATGTTCGCCACCAGCCCGCATACGCTGTACATCCTGCGCATGCTGGTCGGCATCGCCGAGG
CCGGTTTTCTGCCGGGGATCCTCGTCTATCTGACCTGGTGGTTTCCGGCCTACCATCGCGCCCGCGCCAACGCCCTGTTT
ATGATCGCCATGCCGGTGACCATGATGCTCGGCTCGATACTTTCCGGCTATATCCTGGCGCTCGACGGCCTGTGGAACCT
GAAAGGCTGGCAATGGCTATTTCTGCTGGAAGGCCTGCCGTCGGTGGTGCTCGGCGTCGTCACCTGGTTCTTCCTCAACG
ACACGCCGGATAAAGCCAACTGGCTGGACAACGAAGAGAAACAGGCGCTGAAGGCGATGATCGATCGCGAACGGGAACAT
GCGGCGATCGTCCCGGCTTCGCCGCGTTCCACGCTGCGCGAAGTACTGACGCCAGCGGTGCTGATGTATACCCTCGCCTA
CTTCTGCCTGACCAATACCCTCAGCGCCATTAATATCTGGACGCCGCAGATCCTGCAGAGCTTCAACACCGGCAGCAGCA
ACATCATGATTGGCCTGCTGGCGGCGATCCCGCAGTTCTGCACTATTTTCGGCATGATCTGGTGGAGCCGCCGATCCGAC
CGCCGCAAAGAGCGCAAGATGCATACCATCCTGCCCTACCTGTTCGCCGCGGCAGGTTGGCTGCTGGCTTCGGCAACGCA
CCACAGCCTGATCCAACTGATCGGCATTATTATGGCTTCGGTGGGATCCTTTACCGCGATGGCCATTTTCTGGACCACCC
CGGATCGGGTGATCAGCCTGCAGTCGCGCGCGGTGGCGCTGGCGGTGATCAACGCTATCGGCAACGTCGGCTCTGCCGTC
AGCCCGCTGTTGATCGGCATTTTGCGCGATACCACCGGCAGCTTTAGCTCCGGGCTGTGGTTTGTCGCCGGATTACTGAT
CGTCGGCGCGCTGGTGCTTACCCGCATTCCAATGAGCCAGCGTGAGGACGCCGCCGCCACGCCGGGCTTAGCGGCGCAAA
AAGGCCACTAA

Upstream 100 bases:

>100_bases
CACCCTGCTGGCCCGCGGCGCAGAAGCGCTGGCGGCCCGGTTTACCCACACCGCAACCACCACAACCGATAACAATAAAT
CCGTCTATTGAACGGATAAT

Downstream 100 bases:

>100_bases
GGAGCGGGTATGTGCCAGCATTCCATCGCCAACATCGACATCAATAAAGATTACGACGAGAGTCTGGGTACCGAAGAGGT
GCACTACCAGTCGTTCTCCC

Product: 4-hydroxyphenylacetate permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MERNMTTSTLQHNDNKAVEVENRVIKKLFRRLITFLFVLFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYV
LCGIPSNIMLAKVGARRWIAGIMVVWGIASTCTMFATSPHTLYILRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALF
MIAMPVTMMLGSILSGYILALDGLWNLKGWQWLFLLEGLPSVVLGVVTWFFLNDTPDKANWLDNEEKQALKAMIDREREH
AAIVPASPRSTLREVLTPAVLMYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSD
RRKERKMHTILPYLFAAAGWLLASATHHSLIQLIGIIMASVGSFTAMAIFWTTPDRVISLQSRAVALAVINAIGNVGSAV
SPLLIGILRDTTGSFSSGLWFVAGLLIVGALVLTRIPMSQREDAAATPGLAAQKGH

Sequences:

>Translated_456_residues
MERNMTTSTLQHNDNKAVEVENRVIKKLFRRLITFLFVLFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYV
LCGIPSNIMLAKVGARRWIAGIMVVWGIASTCTMFATSPHTLYILRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALF
MIAMPVTMMLGSILSGYILALDGLWNLKGWQWLFLLEGLPSVVLGVVTWFFLNDTPDKANWLDNEEKQALKAMIDREREH
AAIVPASPRSTLREVLTPAVLMYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSD
RRKERKMHTILPYLFAAAGWLLASATHHSLIQLIGIIMASVGSFTAMAIFWTTPDRVISLQSRAVALAVINAIGNVGSAV
SPLLIGILRDTTGSFSSGLWFVAGLLIVGALVLTRIPMSQREDAAATPGLAAQKGH
>Mature_456_residues
MERNMTTSTLQHNDNKAVEVENRVIKKLFRRLITFLFVLFVFSFLDRINIGFAGLTMGKDLGLTSTMFGLAATLFYVTYV
LCGIPSNIMLAKVGARRWIAGIMVVWGIASTCTMFATSPHTLYILRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALF
MIAMPVTMMLGSILSGYILALDGLWNLKGWQWLFLLEGLPSVVLGVVTWFFLNDTPDKANWLDNEEKQALKAMIDREREH
AAIVPASPRSTLREVLTPAVLMYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLLAAIPQFCTIFGMIWWSRRSD
RRKERKMHTILPYLFAAAGWLLASATHHSLIQLIGIIMASVGSFTAMAIFWTTPDRVISLQSRAVALAVINAIGNVGSAV
SPLLIGILRDTTGSFSSGLWFVAGLLIVGALVLTRIPMSQREDAAATPGLAAQKGH

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI87082071, Length=412, Percent_Identity=31.5533980582524, Blast_Score=211, Evalue=5e-56,
Organism=Escherichia coli, GI1789515, Length=438, Percent_Identity=25.1141552511416, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789152, Length=432, Percent_Identity=22.6851851851852, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI87082320, Length=423, Percent_Identity=23.6406619385343, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI2367379, Length=432, Percent_Identity=23.3796296296296, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25141318, Length=401, Percent_Identity=21.9451371571072, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322025, Length=256, Percent_Identity=26.5625, Blast_Score=100, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6319876, Length=264, Percent_Identity=25.3787878787879, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321698, Length=232, Percent_Identity=25.8620689655172, Blast_Score=71, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6323032, Length=209, Percent_Identity=23.444976076555, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6324410, Length=142, Percent_Identity=23.2394366197183, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24583789, Length=383, Percent_Identity=22.4543080939948, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 50404; Mature: 50404

Theoretical pI: Translated: 10.16; Mature: 10.16

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERNMTTSTLQHNDNKAVEVENRVIKKLFRRLITFLFVLFVFSFLDRINIGFAGLTMGKD
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LGLTSTMFGLAATLFYVTYVLCGIPSNIMLAKVGARRWIAGIMVVWGIASTCTMFATSPH
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLYILRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAMPVTMMLGSILSGYILA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
LDGLWNLKGWQWLFLLEGLPSVVLGVVTWFFLNDTPDKANWLDNEEKQALKAMIDREREH
HCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AAIVPASPRSTLREVLTPAVLMYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHH
AAIPQFCTIFGMIWWSRRSDRRKERKMHTILPYLFAAAGWLLASATHHSLIQLIGIIMAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGSFTAMAIFWTTPDRVISLQSRAVALAVINAIGNVGSAVSPLLIGILRDTTGSFSSGLW
HCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHH
FVAGLLIVGALVLTRIPMSQREDAAATPGLAAQKGH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MERNMTTSTLQHNDNKAVEVENRVIKKLFRRLITFLFVLFVFSFLDRINIGFAGLTMGKD
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
LGLTSTMFGLAATLFYVTYVLCGIPSNIMLAKVGARRWIAGIMVVWGIASTCTMFATSPH
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
TLYILRMLVGIAEAGFLPGILVYLTWWFPAYHRARANALFMIAMPVTMMLGSILSGYILA
HHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCEEEHHHHHHHHHHHHHHHHHHHH
LDGLWNLKGWQWLFLLEGLPSVVLGVVTWFFLNDTPDKANWLDNEEKQALKAMIDREREH
HCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AAIVPASPRSTLREVLTPAVLMYTLAYFCLTNTLSAINIWTPQILQSFNTGSSNIMIGLL
CEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHH
AAIPQFCTIFGMIWWSRRSDRRKERKMHTILPYLFAAAGWLLASATHHSLIQLIGIIMAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VGSFTAMAIFWTTPDRVISLQSRAVALAVINAIGNVGSAVSPLLIGILRDTTGSFSSGLW
HCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCHH
FVAGLLIVGALVLTRIPMSQREDAAATPGLAAQKGH
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]