Click here to switch to the map view.

The map label for this gene is cfa [H]

Identifier: 238892858

GI number: 238892858

Start: 663344

End: 664564

Strand: Reverse

Name: cfa [H]

Synonym: KP1_0677

Alternate gene names: 238892858

Gene position: 664564-663344 (Counterclockwise)

Preceding gene: 238892859

Following gene: 238892857

Centisome position: 12.66

GC content: 66.18

Gene sequence:

>1221_bases
ATGACCGATCCCGTCTTTGCGCTTGAACCCGATGTGCCGCGCAACGTGCGGCTCGCGCGCTGGCTGCTTTTTCGTCTGTT
GAGCGGCCTCCGCGAAGGCTCGCTCACCGTGCGCGAAGGGGCGCAGACGTTTCATTTTGGCGACCCCGCCGCCGCGCTGC
GCGCCGAGGCGCGGGTCTGCACGCCGGAGGTGTACTGGCGTCTGCTGACCGGCGGCAGCCTGGCGGCGGCCGAGGCCTGG
ATGGACGGCGACTGGGAGAGCCACCAGCTGACGACGCTGCTGCAGATCCTCGCGCGCAACGGCGAGGTGCTGGGGCGTCT
GGAGCGCGGCTTCCGTCTGCTGGGCAAGCCCGTCGCCCGCCTGCGCCACTGGACCCGCCGCAACACCCGCGCCCAGGCGC
GGGAGAACATCGCCGCCCATTACGACCTCGGCAACGAATTTTATGCCCATTTTCTGGATGACGACCTGCTCTACTCCAGC
GCGCTGTTTACCGACGACCAGCAGGATCTGACCCAGGCCCAGCGGGCCAAGATGGCGCGCCTGTGCGACCAGCTGGCGCT
CACTCCCGGCGATCATCTGCTGGAGATTGGCACCGGCTGGGGGGCGCTGGCCGAGTACGCCGCCCGCCATTACGGCTGCC
GGGTCACCACCACCACCCTTTCCCGGGAGCAGCACCGCTGGGCTACCGAGCGCATGGCCCGCGCCGGGCTGCAGGATCGC
GTCGAGGTGCTGCTCTGCGACTACCGCGATCTGCGCGGCGAGTACGACAAACTGGTGTCGGTGGAGATGATTGAGGCGGT
GGGCCAGCGCTACCTCCCGGCCTTCTTCCGCACCTGTCAGGCGCGCCTGCGCCCGGGCGGTAAAATGGCCCTGCAGGCGA
TCACCATTCAGGATCAGCGCTATCGCGACTACAGCAAAAGCGTCGATTTTATCCAGCGCTACATCTTCCCGGGCGGCTTT
TTGCCCAGCATCACGGCAATGAGCGAGCTGATGACCCGCCATACCGATTTTGTGGTGCGCAACCTGTTCGACATGGGCCC
GGACTATGCCCGCACCCTGGCGCACTGGCGGCAGCGTTTTACCCACGCCTGGCAGGATATTGAAAAGCTCGGCTTTGATG
AGCGCTTCCGCCGGATGTGGCTCTACTACTTCGGCTATTGCGAAGCCGGATTTAACGCCCGCACCATCAGCGTGGTGCAG
CTCACCGCGGAGCGGGTATGA

Upstream 100 bases:

>100_bases
TGACCCTGAAAACCGTCCTCGCCATCTACTGGCAGGCGCTGCGGCTGTGGCTGAAGCGCGTGCCGCTGTACAACCATCCT
GTCAGCAGGAGTGAACGCTC

Downstream 100 bases:

>100_bases
CACGCCCGGCGCAGCACTTGCTGATGGCCCTCGCGTTCGATGTTTACTGGACGCTGGTGGTGATGTTGCGCGAGCGCGGC
CTGCTGATCTGGCTGACGCT

Product: putative cyclopropane-fatty-acyl-phospholipid synthase

Products: NA

Alternate protein names: CFA synthase; Cyclopropane fatty acid synthase [H]

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MTDPVFALEPDVPRNVRLARWLLFRLLSGLREGSLTVREGAQTFHFGDPAAALRAEARVCTPEVYWRLLTGGSLAAAEAW
MDGDWESHQLTTLLQILARNGEVLGRLERGFRLLGKPVARLRHWTRRNTRAQARENIAAHYDLGNEFYAHFLDDDLLYSS
ALFTDDQQDLTQAQRAKMARLCDQLALTPGDHLLEIGTGWGALAEYAARHYGCRVTTTTLSREQHRWATERMARAGLQDR
VEVLLCDYRDLRGEYDKLVSVEMIEAVGQRYLPAFFRTCQARLRPGGKMALQAITIQDQRYRDYSKSVDFIQRYIFPGGF
LPSITAMSELMTRHTDFVVRNLFDMGPDYARTLAHWRQRFTHAWQDIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQ
LTAERV

Sequences:

>Translated_406_residues
MTDPVFALEPDVPRNVRLARWLLFRLLSGLREGSLTVREGAQTFHFGDPAAALRAEARVCTPEVYWRLLTGGSLAAAEAW
MDGDWESHQLTTLLQILARNGEVLGRLERGFRLLGKPVARLRHWTRRNTRAQARENIAAHYDLGNEFYAHFLDDDLLYSS
ALFTDDQQDLTQAQRAKMARLCDQLALTPGDHLLEIGTGWGALAEYAARHYGCRVTTTTLSREQHRWATERMARAGLQDR
VEVLLCDYRDLRGEYDKLVSVEMIEAVGQRYLPAFFRTCQARLRPGGKMALQAITIQDQRYRDYSKSVDFIQRYIFPGGF
LPSITAMSELMTRHTDFVVRNLFDMGPDYARTLAHWRQRFTHAWQDIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQ
LTAERV
>Mature_405_residues
TDPVFALEPDVPRNVRLARWLLFRLLSGLREGSLTVREGAQTFHFGDPAAALRAEARVCTPEVYWRLLTGGSLAAAEAWM
DGDWESHQLTTLLQILARNGEVLGRLERGFRLLGKPVARLRHWTRRNTRAQARENIAAHYDLGNEFYAHFLDDDLLYSSA
LFTDDQQDLTQAQRAKMARLCDQLALTPGDHLLEIGTGWGALAEYAARHYGCRVTTTTLSREQHRWATERMARAGLQDRV
EVLLCDYRDLRGEYDKLVSVEMIEAVGQRYLPAFFRTCQARLRPGGKMALQAITIQDQRYRDYSKSVDFIQRYIFPGGFL
PSITAMSELMTRHTDFVVRNLFDMGPDYARTLAHWRQRFTHAWQDIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQL
TAERV

Specific function: Transfers a methylene group from S-adenosyl-L-methionine to the cis double bond of an unsaturated fatty acid chain resulting in the replacement of the double bond with a methylene bridge [H]

COG id: COG2230

COG function: function code M; Cyclopropane fatty acid synthase and related methyltransferases

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CFA/CMAS family [H]

Homologues:

Organism=Escherichia coli, GI1787951, Length=358, Percent_Identity=36.3128491620112, Blast_Score=203, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI133904226, Length=370, Percent_Identity=39.7297297297297, Blast_Score=255, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003333 [H]

Pfam domain/function: PF02353 CMAS [H]

EC number: =2.1.1.79 [H]

Molecular weight: Translated: 46890; Mature: 46759

Theoretical pI: Translated: 8.35; Mature: 8.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDPVFALEPDVPRNVRLARWLLFRLLSGLREGSLTVREGAQTFHFGDPAAALRAEARVC
CCCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCEEECCCHHHHHHHHHCCC
TPEVYWRLLTGGSLAAAEAWMDGDWESHQLTTLLQILARNGEVLGRLERGFRLLGKPVAR
CHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRHWTRRNTRAQARENIAAHYDLGNEFYAHFLDDDLLYSSALFTDDQQDLTQAQRAKMAR
HHHHHHCCHHHHHHHCCHHHCCCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LCDQLALTPGDHLLEIGTGWGALAEYAARHYGCRVTTTTLSREQHRWATERMARAGLQDR
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHH
VEVLLCDYRDLRGEYDKLVSVEMIEAVGQRYLPAFFRTCQARLRPGGKMALQAITIQDQR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEECHHH
YRDYSKSVDFIQRYIFPGGFLPSITAMSELMTRHTDFVVRNLFDMGPDYARTLAHWRQRF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
THAWQDIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQLTAERV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCC
>Mature Secondary Structure 
TDPVFALEPDVPRNVRLARWLLFRLLSGLREGSLTVREGAQTFHFGDPAAALRAEARVC
CCCCEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEHHCCCCEEECCCHHHHHHHHHCCC
TPEVYWRLLTGGSLAAAEAWMDGDWESHQLTTLLQILARNGEVLGRLERGFRLLGKPVAR
CHHHHHHHHCCCCHHHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRHWTRRNTRAQARENIAAHYDLGNEFYAHFLDDDLLYSSALFTDDQQDLTQAQRAKMAR
HHHHHHCCHHHHHHHCCHHHCCCCHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHHHH
LCDQLALTPGDHLLEIGTGWGALAEYAARHYGCRVTTTTLSREQHRWATERMARAGLQDR
HHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHCCHHHH
VEVLLCDYRDLRGEYDKLVSVEMIEAVGQRYLPAFFRTCQARLRPGGKMALQAITIQDQR
HHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEEEECHHH
YRDYSKSVDFIQRYIFPGGFLPSITAMSELMTRHTDFVVRNLFDMGPDYARTLAHWRQRF
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
THAWQDIEKLGFDERFRRMWLYYFGYCEAGFNARTISVVQLTAERV
HHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]