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The map label for this gene is srlA [H]

Identifier: 238892799

GI number: 238892799

Start: 597002

End: 597523

Strand: Reverse

Name: srlA [H]

Synonym: KP1_0608

Alternate gene names: 238892799

Gene position: 597523-597002 (Counterclockwise)

Preceding gene: 238892800

Following gene: 238892798

Centisome position: 11.38

GC content: 59.96

Gene sequence:

>522_bases
ATGTTTCTGGTCTCCCTGGCTGAAGGCTTTATCCACCTGTTCCAGGCCGCAGGCAAAATCTTCCTCGACATGATGACCGG
GCTAATCCCGATGCTCATCTGCCTGCTGCTGGCCATCAACTTCCTGATGAAGCTGGTCGGCATCGTGCGGATGGAGAAGG
TCGCTGCCCTGCTCGGCCGCTCGCGCATTCTCACCTACGGCGTGTTGCCAGTGCTCGGCTGGTTCTTTATGAGTAGCCCC
GGCGCGCTGACGCTCGGTAAGCTCTTACCTGAGAAGAGTAAACCCGGCTATGAGGATGCACTCGGCACCACCGCCCATCC
CCTCACCAGCCTGTTTCCCCACGTAGTGCCATCAGAGCTGTTTGTCTGGCTCGGCGTGGCTGCGGGGGTTAAGGCGCTCG
GCCTGCCCGTCACCTCGCTGGCGCTGCGTTATATCGCTGCCGCCATGTTGATTGGTTTAATCCGCGGGATTATCACCGAG
TACCTGTTCCTGCGGCTCAGCAAGCGGGGGAATGCGCCATGA

Upstream 100 bases:

>100_bases
TGAGTGGCAGGACGCATTAACCAACGATACCTGACAGGAGAGTTGTTTATGCACACCGAACCACAACCATGCACCATCAT
ACCCATCGCAGGAGGCCGCC

Downstream 100 bases:

>100_bases
TGATTTACTGCGCACGTATTACTGCTATCGGGCTGTTTGTCGCTGACGGCCTGACCGACAAGATACTCATCACCTTCGAC
AGCAACGGGCCGAAGGACTG

Product: putative glucitol/sorbitol-specific PTS family enzyme II component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIC-Gut; PTS system glucitol/sorbitol-specific EIIC component [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGIVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSKRGNAP

Sequences:

>Translated_173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGIVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSKRGNAP
>Mature_173_residues
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGIVRMEKVAALLGRSRILTYGVLPVLGWFFMSSP
GALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSELFVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITE
YLFLRLSKRGNAP

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG3730

COG function: function code G; Phosphotransferase system sorbitol-specific component IIC

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIC type-5 domain [H]

Homologues:

Organism=Escherichia coli, GI48994904, Length=154, Percent_Identity=40.2597402597403, Blast_Score=128, Evalue=2e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004699 [H]

Pfam domain/function: PF03608 EII-GUT [H]

EC number: 2.7.1.69

Molecular weight: Translated: 18696; Mature: 18696

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS51107 PTS_EIIC_TYPE_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGIVRMEKVAALLGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSEL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
FVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSKRGNAP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFLVSLAEGFIHLFQAAGKIFLDMMTGLIPMLICLLLAINFLMKLVGIVRMEKVAALLGR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SRILTYGVLPVLGWFFMSSPGALTLGKLLPEKSKPGYEDALGTTAHPLTSLFPHVVPSEL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHHH
FVWLGVAAGVKALGLPVTSLALRYIAAAMLIGLIRGIITEYLFLRLSKRGNAP
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9435786 [H]