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The map label for this gene is treR [H]

Identifier: 238892737

GI number: 238892737

Start: 523919

End: 524866

Strand: Reverse

Name: treR [H]

Synonym: KP1_0532

Alternate gene names: 238892737

Gene position: 524866-523919 (Counterclockwise)

Preceding gene: 238892739

Following gene: 238892736

Centisome position: 10.0

GC content: 63.61

Gene sequence:

>948_bases
ATGCAGAACCGGCTGACCATCAAAGATATCGCGCGCTTAAGCGGCGTAGGGAAATCGACGGTATCCCGCGTCCTTAACAA
CGAGAGCGGGGTCAGCGAACGGACCCGCGAGCGCGTCGAAGCGGTGATGCAGCAGCACGGTTTCTCGCCTTCCCGTTCCG
CCCGCGCCATGCGCGGCCAGAGCGATAAAGTGGTGGCGATTATCGTCACCCGTCTCGATTCGCTGTCGGAAAACCTTGCC
GTGCAGACCATGCTGCCCGCCTTTTATGAGCAGGGTTACGATCCGATTATGATGGAGAGCCAGTTCTCCCCGGCGTTGGT
GGAGGAGCATCTCGGCATGCTCGCCCGGCGCAATATTGACGGCGTGGTGCTGTTCGGTTTTACCGGCATCGACGAAGCGA
TGCTCGCCCCCTGGCGCGACACCCTGGTGCTGATGGCCCGCGACGCTCCCGGCTTCGCCTCGGTGTGCTATGACGACGAG
GGGGCCATCACGCTGCTGATGCAGCGGCTCTACGATCGCGGACACCGCCACATCAGTTTTCTTGGCGTACCGCACAGCGA
CGTCACCACCGGCGAACGCCGCCATCTGGCCTATCTCACCTTCTGTGAAAAGCATCGTCTGACGCCCACCGCCGCCCTGC
CGGGGCTGGGCATGAAGCAGGGATATGACACCGTCGCCAGCGTGCTGATGGCTGAAACCAGCGCCCTGGTCTGCGCGACG
GATACCCTCGCTCTCGGCGCCAGCAAGTACCTCCAGCAGCAGGGTCGCGATGCGCTGCAGCTCGCCAGCGTCGGCAGCAC
GCCGCTGATGAAGTTTCTCCACCCGGAAATCTTGACCGTCGATCCGGGCTATGCCGAGTCCGGACGCCGGGCCGCCCGGC
AGTTGATCGAGCAGATCGCCGGCAGCGTCGATCCCCGCCAGATCGTGATTCCCGCCGCCCTCAATTAA

Upstream 100 bases:

>100_bases
AAACCCGCGCAACTAAACCGAACGTAAACCAGACTTTGCTCATTGCGGTTTGGTTGAGTAGCATTAGGCTCACTTCTACC
ATCCCTGACGAGAATTCCGC

Downstream 100 bases:

>100_bases
TCTCGCTCGGGCGATTTATGTGATCGTCGCCGGGTTTCGGGAACGTTCCCATTTTGCAAATTAAGCGGAACGGTTAGGAT
GCCCTCAAGGTAAAAACGGC

Product: trehalose repressor

Products: NA

Alternate protein names: Trehalose operon repressor [H]

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMQQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLA
VQTMLPAFYEQGYDPIMMESQFSPALVEEHLGMLARRNIDGVVLFGFTGIDEAMLAPWRDTLVLMARDAPGFASVCYDDE
GAITLLMQRLYDRGHRHISFLGVPHSDVTTGERRHLAYLTFCEKHRLTPTAALPGLGMKQGYDTVASVLMAETSALVCAT
DTLALGASKYLQQQGRDALQLASVGSTPLMKFLHPEILTVDPGYAESGRRAARQLIEQIAGSVDPRQIVIPAALN

Sequences:

>Translated_315_residues
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMQQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLA
VQTMLPAFYEQGYDPIMMESQFSPALVEEHLGMLARRNIDGVVLFGFTGIDEAMLAPWRDTLVLMARDAPGFASVCYDDE
GAITLLMQRLYDRGHRHISFLGVPHSDVTTGERRHLAYLTFCEKHRLTPTAALPGLGMKQGYDTVASVLMAETSALVCAT
DTLALGASKYLQQQGRDALQLASVGSTPLMKFLHPEILTVDPGYAESGRRAARQLIEQIAGSVDPRQIVIPAALN
>Mature_315_residues
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMQQHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLA
VQTMLPAFYEQGYDPIMMESQFSPALVEEHLGMLARRNIDGVVLFGFTGIDEAMLAPWRDTLVLMARDAPGFASVCYDDE
GAITLLMQRLYDRGHRHISFLGVPHSDVTTGERRHLAYLTFCEKHRLTPTAALPGLGMKQGYDTVASVLMAETSALVCAT
DTLALGASKYLQQQGRDALQLASVGSTPLMKFLHPEILTVDPGYAESGRRAARQLIEQIAGSVDPRQIVIPAALN

Specific function: Repressor of the treBC operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790689, Length=315, Percent_Identity=82.2222222222222, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI1788474, Length=317, Percent_Identity=26.4984227129338, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1787906, Length=279, Percent_Identity=29.3906810035842, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI1789202, Length=287, Percent_Identity=25.7839721254355, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1787580, Length=332, Percent_Identity=27.4096385542169, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790194, Length=293, Percent_Identity=24.2320819112628, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1786540, Length=274, Percent_Identity=25.1824817518248, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1787948, Length=254, Percent_Identity=24.8031496062992, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI48994940, Length=321, Percent_Identity=21.8068535825545, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789068, Length=266, Percent_Identity=24.812030075188, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1790715, Length=315, Percent_Identity=21.9047619047619, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761
- InterPro:   IPR012771 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 34486; Mature: 34486

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMQQHGFSPSRSARAMRGQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQFSPALVEEHLGMLARRNID
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
GVVLFGFTGIDEAMLAPWRDTLVLMARDAPGFASVCYDDEGAITLLMQRLYDRGHRHISF
EEEEEEECCCCHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEE
LGVPHSDVTTGERRHLAYLTFCEKHRLTPTAALPGLGMKQGYDTVASVLMAETSALVCAT
EECCCCCCCCCCCHHHHHEEHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEH
DTLALGASKYLQQQGRDALQLASVGSTPLMKFLHPEILTVDPGYAESGRRAARQLIEQIA
HHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
GSVDPRQIVIPAALN
CCCCCCEEEECCCCC
>Mature Secondary Structure
MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSERTRERVEAVMQQHGFSPSRSARAMRGQ
CCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHCCC
SDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQFSPALVEEHLGMLARRNID
CCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHCCCC
GVVLFGFTGIDEAMLAPWRDTLVLMARDAPGFASVCYDDEGAITLLMQRLYDRGHRHISF
EEEEEEECCCCHHHHCCCCCEEEEEEECCCCCEEEEECCCCHHHHHHHHHHHCCCCEEEE
LGVPHSDVTTGERRHLAYLTFCEKHRLTPTAALPGLGMKQGYDTVASVLMAETSALVCAT
EECCCCCCCCCCCHHHHHEEHHHHCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCEEEEEH
DTLALGASKYLQQQGRDALQLASVGSTPLMKFLHPEILTVDPGYAESGRRAARQLIEQIA
HHHHHHHHHHHHHHCCHHHHHHHCCCCHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHH
GSVDPRQIVIPAALN
CCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7751273; 11677609 [H]