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The map label for this gene is phnF [H]

Identifier: 238892588

GI number: 238892588

Start: 374345

End: 375076

Strand: Reverse

Name: phnF [H]

Synonym: KP1_0366

Alternate gene names: 238892588

Gene position: 375076-374345 (Counterclockwise)

Preceding gene: 238892589

Following gene: 238892587

Centisome position: 7.15

GC content: 63.93

Gene sequence:

>732_bases
ATGACCATGCACCTGTCCAGACATCCGACCAGTTACCCCACGCGCTATCAGGAAATCGCCGCCCGACTTGAGCAGGAGCT
GCGCCACCACTATCGCTGCGGCGACTATCTGCCCGCCGAGCAGCAGCTGGCGACGCGCTTCGACGTTAACCGCCACACCC
TGCGCCGGGCTATCGACCAGCTGGTTGAGCGCGGCTGGGTTCAGCGCCGTCAGGGCGTGGGTGTGCTGGTGCTGATGCGC
CCCATCGACTACCCGCTTAACGCCCAGGCGCGCTTCAGCCAAAACCTGCTGGAACAAGGCAGCGATCCCACCAGCGAAAA
GCTGCTGTCGGTGCTGCGCCCCGCCAGCGCCCATGTCGCCGAGGCCTTTGGCATCAATGAGGGCGAGAACGTGATCCACC
TGCGTACCCTGCGCCGGGTCAATGGCGTCGCCCTGTGCCTGATTGACCACTACTTCGCTGACCTGCGCTTCTGGCCGGTG
CTACAGACCTTCAGCCACGGCTCGCTGCACGATCTGCTACGCGATCGGCTCGACGTCGAACTGACCCGCGTACGCACCAA
AATTAGCGCCCGCCGCGCGCAGGCAAAAGAGAGCAAGCTGCTGGAAATCCCCAATATGGCGCCGCTGCTCTGCGTCCGCA
CGCTCAATAGCCGCGAGGGCGAGTCGCTCACGGCGGAGTACTCCGTCAGCCTGACCCGCGCCGACATGATTGAATTTACC
ATGGAGCACTGA

Upstream 100 bases:

>100_bases
TCATCCTTTAGTCATCGTCACTTAACCGAAATGCAACATAAACCGGTCAGGATCGGCCCACAACGCGAGGAAGCTCCTCG
CCTATGCTGTGTGAGGCTTG

Downstream 100 bases:

>100_bases
ATGCACTTCGATACCGCCACCCGCCAGCGCTGGATGTCCGTGCTGGCCCACAGTGAACCGCAGGACCTTCTGGCGCGCAT
GCAGTCCCTGCAGCTGGCGC

Product: phosphonate metabolism transcriptional regulator PhnF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MTMHLSRHPTSYPTRYQEIAARLEQELRHHYRCGDYLPAEQQLATRFDVNRHTLRRAIDQLVERGWVQRRQGVGVLVLMR
PIDYPLNAQARFSQNLLEQGSDPTSEKLLSVLRPASAHVAEAFGINEGENVIHLRTLRRVNGVALCLIDHYFADLRFWPV
LQTFSHGSLHDLLRDRLDVELTRVRTKISARRAQAKESKLLEIPNMAPLLCVRTLNSREGESLTAEYSVSLTRADMIEFT
MEH

Sequences:

>Translated_243_residues
MTMHLSRHPTSYPTRYQEIAARLEQELRHHYRCGDYLPAEQQLATRFDVNRHTLRRAIDQLVERGWVQRRQGVGVLVLMR
PIDYPLNAQARFSQNLLEQGSDPTSEKLLSVLRPASAHVAEAFGINEGENVIHLRTLRRVNGVALCLIDHYFADLRFWPV
LQTFSHGSLHDLLRDRLDVELTRVRTKISARRAQAKESKLLEIPNMAPLLCVRTLNSREGESLTAEYSVSLTRADMIEFT
MEH
>Mature_242_residues
TMHLSRHPTSYPTRYQEIAARLEQELRHHYRCGDYLPAEQQLATRFDVNRHTLRRAIDQLVERGWVQRRQGVGVLVLMRP
IDYPLNAQARFSQNLLEQGSDPTSEKLLSVLRPASAHVAEAFGINEGENVIHLRTLRRVNGVALCLIDHYFADLRFWPVL
QTFSHGSLHDLLRDRLDVELTRVRTKISARRAQAKESKLLEIPNMAPLLCVRTLNSREGESLTAEYSVSLTRADMIEFTM
EH

Specific function: Belongs to an operon involved in alkylphosphonate uptake and C-P lyase. Exact function not known. By similarity could be a transcriptional regulator [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790540, Length=241, Percent_Identity=84.2323651452282, Blast_Score=422, Evalue=1e-119,
Organism=Escherichia coli, GI1790118, Length=233, Percent_Identity=29.6137339055794, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1786950, Length=201, Percent_Identity=27.8606965174129, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI87082252, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI1788418, Length=214, Percent_Identity=25.2336448598131, Blast_Score=64, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012702
- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 28048; Mature: 27916

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMHLSRHPTSYPTRYQEIAARLEQELRHHYRCGDYLPAEQQLATRFDVNRHTLRRAIDQ
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
LVERGWVQRRQGVGVLVLMRPIDYPLNAQARFSQNLLEQGSDPTSEKLLSVLRPASAHVA
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
EAFGINEGENVIHLRTLRRVNGVALCLIDHYFADLRFWPVLQTFSHGSLHDLLRDRLDVE
HHHCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTRVRTKISARRAQAKESKLLEIPNMAPLLCVRTLNSREGESLTAEYSVSLTRADMIEFT
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEHHHEEEHHHHHHHHHH
MEH
CCC
>Mature Secondary Structure 
TMHLSRHPTSYPTRYQEIAARLEQELRHHYRCGDYLPAEQQLATRFDVNRHTLRRAIDQ
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHHHHHHHH
LVERGWVQRRQGVGVLVLMRPIDYPLNAQARFSQNLLEQGSDPTSEKLLSVLRPASAHVA
HHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHHH
EAFGINEGENVIHLRTLRRVNGVALCLIDHYFADLRFWPVLQTFSHGSLHDLLRDRLDVE
HHHCCCCCCCEEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LTRVRTKISARRAQAKESKLLEIPNMAPLLCVRTLNSREGESLTAEYSVSLTRADMIEFT
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEHHHEEEHHHHHHHHHH
MEH
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155230; 1840580; 7610040; 9278503 [H]