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The map label for this gene is cidA [H]

Identifier: 238892558

GI number: 238892558

Start: 342743

End: 343150

Strand: Direct

Name: cidA [H]

Synonym: KP1_0331

Alternate gene names: 238892558

Gene position: 342743-343150 (Clockwise)

Preceding gene: 238892556

Following gene: 238892559

Centisome position: 6.53

GC content: 59.56

Gene sequence:

>408_bases
ATGGCCTTCGCGCCAGCTCGCGTTGCCCCCGCCGTGGCGCAACGACTTCAGATCCCGGTACAGGTACTTCTCTACGTCGG
GTTATTCATCTTCGCACAATATCTGGTGAACAGGTGGCAGGTACCGCTGCCGGCTAACCTGGTCGGCATGGTGATGCTCC
TGCTGCTGATCGTCTGCCGGGTGATACCGGTAAGCTGGGTGCGCGCCGGCGCCCGCTGGCTGCTGGCGGAGATGCTGCTG
TTTTTCGTCCCGGCGGTGGTCGCGGTGGTGAACTACGCCCAGCTGTTGATGGTCGATGGTTGGCGGATTTTTCTGGTGAT
TGCCTTAAGCACGCTGATGGTGCTCGGTGCCACCGCCTGGGTCGTTGACAAGGTCTATCGTTACGAAGTGGGCAGGTTAA
AAAAATGA

Upstream 100 bases:

>100_bases
TTCCCTGAGACTATACCTGCGATGATTTTAATTCATTTCTGTCCGCTTCGGCGGCTCTCTATACTGCTCGCCTGACTTCT
TTTTTTCAGGACTATCGCAC

Downstream 100 bases:

>100_bases
GCGATGCCGTGCTGAGTATCCTGTGCCTGGTGGCGACGCTGGTCCTCTATTACGCCAACAAAAAACTGTATCGCCGTTTT
CATAAACTCCCTCTGATGCC

Product: putative inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 135; Mature: 134

Protein sequence:

>135_residues
MAFAPARVAPAVAQRLQIPVQVLLYVGLFIFAQYLVNRWQVPLPANLVGMVMLLLLIVCRVIPVSWVRAGARWLLAEMLL
FFVPAVVAVVNYAQLLMVDGWRIFLVIALSTLMVLGATAWVVDKVYRYEVGRLKK

Sequences:

>Translated_135_residues
MAFAPARVAPAVAQRLQIPVQVLLYVGLFIFAQYLVNRWQVPLPANLVGMVMLLLLIVCRVIPVSWVRAGARWLLAEMLL
FFVPAVVAVVNYAQLLMVDGWRIFLVIALSTLMVLGATAWVVDKVYRYEVGRLKK
>Mature_134_residues
AFAPARVAPAVAQRLQIPVQVLLYVGLFIFAQYLVNRWQVPLPANLVGMVMLLLLIVCRVIPVSWVRAGARWLLAEMLLF
FVPAVVAVVNYAQLLMVDGWRIFLVIALSTLMVLGATAWVVDKVYRYEVGRLKK

Specific function: Increases the activity of extracellular murein hydrolases possibly by mediating their export via hole formation. Inhibited by the antiholin-like proteins LrgAB. In an unstressed cell, the LrgAB products probably inhibit the function of the CidA protein. W

COG id: COG1380

COG function: function code R; Putative effector of murein hydrolase LrgA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CidA/LrgA family. CidA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005538 [H]

Pfam domain/function: PF03788 LrgA [H]

EC number: NA

Molecular weight: Translated: 15182; Mature: 15051

Theoretical pI: Translated: 10.84; Mature: 10.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFAPARVAPAVAQRLQIPVQVLLYVGLFIFAQYLVNRWQVPLPANLVGMVMLLLLIVCR
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VIPVSWVRAGARWLLAEMLLFFVPAVVAVVNYAQLLMVDGWRIFLVIALSTLMVLGATAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVDKVYRYEVGRLKK
HHHHHHHHHHHCCCC
>Mature Secondary Structure 
AFAPARVAPAVAQRLQIPVQVLLYVGLFIFAQYLVNRWQVPLPANLVGMVMLLLLIVCR
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
VIPVSWVRAGARWLLAEMLLFFVPAVVAVVNYAQLLMVDGWRIFLVIALSTLMVLGATAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
VVDKVYRYEVGRLKK
HHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA