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The map label for this gene is mltF [H]

Identifier: 238892533

GI number: 238892533

Start: 316330

End: 317991

Strand: Reverse

Name: mltF [H]

Synonym: KP1_0303

Alternate gene names: 238892533

Gene position: 317991-316330 (Counterclockwise)

Preceding gene: 238892536

Following gene: 238892531

Centisome position: 6.06

GC content: 55.17

Gene sequence:

>1662_bases
ATGTTTTTTACGCCCTTGTCGTTCCCAGCTAACGGCGGCCGTTCTGCTAAAATAATCACATCCCCTGCGGAGTATTCCTC
CATGAACGCCTACTCGCTATCACGTCTGTTTATCGCCTGGCTCACCTGCCTCGCGACACTGTTATTCGCTCCTCTGCTGC
CGGCAGTAGAGGCGGAAAAAGCGCCGCCGGCAGCAGCCGAAGACAACACACTGTCGATTCATATTGACGATATGCTACGG
CCATGGAGAGGCGATTTGCCTGGCATGATCGACCGTCGTACCATTCGGGTATTAACCACCTACAGCAAGACCTTCTTTTT
TATTGATAAAGGCACCCAGCGCGGGGCGACGCACGACATTTTTATCGCGCTGGAAAACGATCTGAATAAACAGCTAGCGA
AGGATAAAAAGCTCAAACAGCGCCACCTGAAGCTGCATATCGTTTTTGTGCCGGTCAGTCGGGATAATCTCTTTATCGCG
CTTAATGAAGGTAAAGGCGATATTGCGGCTGCCAATCTGACTATCACGCCCTCGCGGGAAGCCCAGGTCGATTTCGCCCA
GCCGCTCTACAGCAACGTGAAAGAATTACTGATCTCCGGCCCGGCTTCACCGAAGGTCGACAGCCTGGAGCAACTCTCTG
GTCAAACCGTCTTTGTTCGCCGCTCCTCCAGCTATTACGACAGCCTGCAAGCGCTGAACGCCCGATTTGCCGGTGAGTCG
CGCCCACCGGTGATACTGGAGGCGGCGCCGGAAGCGCTGGAGGATGAAGATCTGCTGGAAATGCTCAACGCCGGGCTGAT
TCCGCTGATCGTCGTCGATCAGCATAAGGCGTTGTTCTGGAAACAGGTGTTTCCAAAAATTCAAGTCCATGACAACGTGG
TGCTGCGCGACGGCGGCGACATTGCCTGGGCGGTACGCAAAGACAGCCCGCAGCTGCTGACGGTACTGAACAACTTCGTC
AAAAAGAATCGTCAGGGCACCACGCTGGGCAATACTCTCCTGCTGCGTTACCTGAAAAATGCTAAATATGTCAAAAATGC
CGCAGCGAATAAGGAACGACGCAAATTCCTCGCGATGGTAGATGTCTTCCGCAAGTACGGCGATCGTTATGACGTCGACT
GGCTGCTGATGGCGGCCCAGGGATACCAGGAGTCGCGGCTGAATCAGTCGGTACGGAGCCACGTCGGCGCCATCGGCGTT
ATGCAGGTGATGCCCAGCACTGGAAAAGAGCTGAAGGTGGGTGATATTAAACAGCTGGATCCCAATATCCATGCCGGCGT
GAAATACATGCGCTGGATGATGGATCGGTACTATGCCGATGAGCCCATGACCCGGCTCGATAAAGCGCTGTTTACCTTTG
CCTCCTATAACGCGGGTCCGGCGCGTATCGCCCGCCTGCGCACCATGACTAAACAGCGAGGATTTGACCCGAACGTCTGG
TTCGGTAACGTCGAAAATATGGCGGCAGAAAAAATTGGCGCCGAGACGGTAACCTACGTCAGCAATATCTATAAGTATTA
CATCGCCTATCGGCTGATCGTCGATGACATGGCCCGCAAACAGAAAGCGACGGCCGTACCGCGGCAGGAGCCGGTGGCGC
AGCCAGTCAAACCGCAGCCCAGCGTGGCGACAGCCGCCACCGCTCAGGTGCCCGTCATCTGA

Upstream 100 bases:

>100_bases
AACACACATTTTCGCCATATTATCTCCATAGTTAAATTAAAGATAAAAACACATTAATAGTAAGCGATAAAATGGGAGAA
AACTATTTGTCGGCATTGTT

Downstream 100 bases:

>100_bases
ATCGCCCGTCACCGCGGGTCAAATCTCATCCTGAAATGACGGAGCAGGAATAATAAAGTAAAAGCCCCGGCGAAACCGGG
GCTTTCTGTTTTCGACTACG

Product: putative periplasmic binding protein of transport system

Products: NA

Alternate protein names: Murein lyase F [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MFFTPLSFPANGGRSAKIITSPAEYSSMNAYSLSRLFIAWLTCLATLLFAPLLPAVEAEKAPPAAAEDNTLSIHIDDMLR
PWRGDLPGMIDRRTIRVLTTYSKTFFFIDKGTQRGATHDIFIALENDLNKQLAKDKKLKQRHLKLHIVFVPVSRDNLFIA
LNEGKGDIAAANLTITPSREAQVDFAQPLYSNVKELLISGPASPKVDSLEQLSGQTVFVRRSSSYYDSLQALNARFAGES
RPPVILEAAPEALEDEDLLEMLNAGLIPLIVVDQHKALFWKQVFPKIQVHDNVVLRDGGDIAWAVRKDSPQLLTVLNNFV
KKNRQGTTLGNTLLLRYLKNAKYVKNAAANKERRKFLAMVDVFRKYGDRYDVDWLLMAAQGYQESRLNQSVRSHVGAIGV
MQVMPSTGKELKVGDIKQLDPNIHAGVKYMRWMMDRYYADEPMTRLDKALFTFASYNAGPARIARLRTMTKQRGFDPNVW
FGNVENMAAEKIGAETVTYVSNIYKYYIAYRLIVDDMARKQKATAVPRQEPVAQPVKPQPSVATAATAQVPVI

Sequences:

>Translated_553_residues
MFFTPLSFPANGGRSAKIITSPAEYSSMNAYSLSRLFIAWLTCLATLLFAPLLPAVEAEKAPPAAAEDNTLSIHIDDMLR
PWRGDLPGMIDRRTIRVLTTYSKTFFFIDKGTQRGATHDIFIALENDLNKQLAKDKKLKQRHLKLHIVFVPVSRDNLFIA
LNEGKGDIAAANLTITPSREAQVDFAQPLYSNVKELLISGPASPKVDSLEQLSGQTVFVRRSSSYYDSLQALNARFAGES
RPPVILEAAPEALEDEDLLEMLNAGLIPLIVVDQHKALFWKQVFPKIQVHDNVVLRDGGDIAWAVRKDSPQLLTVLNNFV
KKNRQGTTLGNTLLLRYLKNAKYVKNAAANKERRKFLAMVDVFRKYGDRYDVDWLLMAAQGYQESRLNQSVRSHVGAIGV
MQVMPSTGKELKVGDIKQLDPNIHAGVKYMRWMMDRYYADEPMTRLDKALFTFASYNAGPARIARLRTMTKQRGFDPNVW
FGNVENMAAEKIGAETVTYVSNIYKYYIAYRLIVDDMARKQKATAVPRQEPVAQPVKPQPSVATAATAQVPVI
>Mature_553_residues
MFFTPLSFPANGGRSAKIITSPAEYSSMNAYSLSRLFIAWLTCLATLLFAPLLPAVEAEKAPPAAAEDNTLSIHIDDMLR
PWRGDLPGMIDRRTIRVLTTYSKTFFFIDKGTQRGATHDIFIALENDLNKQLAKDKKLKQRHLKLHIVFVPVSRDNLFIA
LNEGKGDIAAANLTITPSREAQVDFAQPLYSNVKELLISGPASPKVDSLEQLSGQTVFVRRSSSYYDSLQALNARFAGES
RPPVILEAAPEALEDEDLLEMLNAGLIPLIVVDQHKALFWKQVFPKIQVHDNVVLRDGGDIAWAVRKDSPQLLTVLNNFV
KKNRQGTTLGNTLLLRYLKNAKYVKNAAANKERRKFLAMVDVFRKYGDRYDVDWLLMAAQGYQESRLNQSVRSHVGAIGV
MQVMPSTGKELKVGDIKQLDPNIHAGVKYMRWMMDRYYADEPMTRLDKALFTFASYNAGPARIARLRTMTKQRGFDPNVW
FGNVENMAAEKIGAETVTYVSNIYKYYIAYRLIVDDMARKQKATAVPRQEPVAQPVKPQPSVATAATAQVPVI

Specific function: Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the

COG id: COG4623

COG function: function code M; Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein

Gene ontology:

Cell location: Cell outer membrane; Peripheral membrane protein. Note=Attached to the inner leaflet of the outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI171474010, Length=428, Percent_Identity=24.2990654205607, Blast_Score=84, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR001638
- InterPro:   IPR000189 [H]

Pfam domain/function: PF00497 SBP_bac_3; PF01464 SLT [H]

EC number: NA

Molecular weight: Translated: 62015; Mature: 62015

Theoretical pI: Translated: 9.96; Mature: 9.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFFTPLSFPANGGRSAKIITSPAEYSSMNAYSLSRLFIAWLTCLATLLFAPLLPAVEAEK
CCCCCCCCCCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APPAAAEDNTLSIHIDDMLRPWRGDLPGMIDRRTIRVLTTYSKTFFFIDKGTQRGATHDI
CCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEEEEEECEEEEEEECCCCCCCCEEE
FIALENDLNKQLAKDKKLKQRHLKLHIVFVPVSRDNLFIALNEGKGDIAAANLTITPSRE
EEEECCHHHHHHHHHHHHHHHCEEEEEEEEEECCCCEEEEEECCCCCEEEEEEEECCCCC
AQVDFAQPLYSNVKELLISGPASPKVDSLEQLSGQTVFVRRSSSYYDSLQALNARFAGES
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCC
RPPVILEAAPEALEDEDLLEMLNAGLIPLIVVDQHKALFWKQVFPKIQVHDNVVLRDGGD
CCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEECCCEEEECCCC
IAWAVRKDSPQLLTVLNNFVKKNRQGTTLGNTLLLRYLKNAKYVKNAAANKERRKFLAMV
EEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
DVFRKYGDRYDVDWLLMAAQGYQESRLNQSVRSHVGAIGVMQVMPSTGKELKVGDIKQLD
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCHHHCC
PNIHAGVKYMRWMMDRYYADEPMTRLDKALFTFASYNAGPARIARLRTMTKQRGFDPNVW
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCE
FGNVENMAAEKIGAETVTYVSNIYKYYIAYRLIVDDMARKQKATAVPRQEPVAQPVKPQP
ECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SVATAATAQVPVI
CCCCCCCCCCCCC
>Mature Secondary Structure
MFFTPLSFPANGGRSAKIITSPAEYSSMNAYSLSRLFIAWLTCLATLLFAPLLPAVEAEK
CCCCCCCCCCCCCCCEEEEECCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
APPAAAEDNTLSIHIDDMLRPWRGDLPGMIDRRTIRVLTTYSKTFFFIDKGTQRGATHDI
CCCCCCCCCEEEEEEHHHCCCCCCCCCCCCCCCEEEEEEEECEEEEEEECCCCCCCCEEE
FIALENDLNKQLAKDKKLKQRHLKLHIVFVPVSRDNLFIALNEGKGDIAAANLTITPSRE
EEEECCHHHHHHHHHHHHHHHCEEEEEEEEEECCCCEEEEEECCCCCEEEEEEEECCCCC
AQVDFAQPLYSNVKELLISGPASPKVDSLEQLSGQTVFVRRSSSYYDSLQALNARFAGES
CCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCCEEEEEECCHHHHHHHHHHHHHCCCC
RPPVILEAAPEALEDEDLLEMLNAGLIPLIVVDQHKALFWKQVFPKIQVHDNVVLRDGGD
CCCEEEECCCCCCCHHHHHHHHCCCCEEEEEECCCHHHHHHHHCCCEEECCCEEEECCCC
IAWAVRKDSPQLLTVLNNFVKKNRQGTTLGNTLLLRYLKNAKYVKNAAANKERRKFLAMV
EEEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHH
DVFRKYGDRYDVDWLLMAAQGYQESRLNQSVRSHVGAIGVMQVMPSTGKELKVGDIKQLD
HHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCCCEEECCCHHHCC
PNIHAGVKYMRWMMDRYYADEPMTRLDKALFTFASYNAGPARIARLRTMTKQRGFDPNVW
CCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCE
FGNVENMAAEKIGAETVTYVSNIYKYYIAYRLIVDDMARKQKATAVPRQEPVAQPVKPQP
ECCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCC
SVATAATAQVPVI
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA