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The map label for this gene is aphA [H]

Identifier: 238892528

GI number: 238892528

Start: 310962

End: 311696

Strand: Direct

Name: aphA [H]

Synonym: KP1_0297

Alternate gene names: 238892528

Gene position: 310962-311696 (Clockwise)

Preceding gene: 238892527

Following gene: 238892529

Centisome position: 5.92

GC content: 58.78

Gene sequence:

>735_bases
TTGATAGATTTAGGGATAAATATGCGCAAACTTACTCTCGCCCTTGCGGCGGCTTCTCTCCTGTTCACGCTGAACAGCGC
CGTTGTGGCGCGCGCCTCCACGCCGCAGCCGCTGTGGGTCGGCACCAACGTGGCCCAGCTGGCCGAGCAGGCGCCGATCC
ACTGGGTTTCGGTGGCGCAAATTGAGAACAGCCTGCTGGGGCGGCCGCCGATGGCCGTCGGCTTTGATATCGATGACACC
GTCCTCTTCTCCAGTCCGGGTTTCTGGCGCGGGCAAAAAACCTTCTCTCCCGGCAGCGAGGATTACCTGAAAAACCCGCA
GTTCTGGGAAAAAATGAACAATGGCTGGGATGAATTCAGCATGCCGAAAGAGGTGGCGCGCCAGCTGATTGCGATGCATG
TGAAGCGCGGGGACAGCATCTGGTTCGTCACCGGCCGCAGCCAGACCAAAACCGAAACCGTTTCTAAAACCCTGCAGGAT
GATTTTCTCATCCCGGCCGCCAATATGAATCCGGTGATTTTCGCTGGCGATAAGCCTGGCCAAAACACCAAGACCCAGTG
GCTGCAGGCGAAGCAGATAAAGGTTTTCTACGGCGATTCGGATAACGATATCACCGCCGCCCGCGAAGCGGGCGCCCGTG
GCATCCGCGTGCTGCGGGCCGCCAACTCCTCCTATAAGCCGTTGCCGATGGCTGGCGCGCTGGGCGAGGAAGTAATCGTC
AATTCCGAATACTGA

Upstream 100 bases:

>100_bases
TTTTTCTATGACATCTGCGCGAAAAAGGCTTTTCATCCATGCCGCCGGCGGGTAAGGTCGGGACGTTGATAAGCATGCAC
ATTATTGAAAACAATAATGA

Downstream 100 bases:

>100_bases
TGACCGCCTGAACGCGATAAACGGCAGCGACGGCGCTGCCGTTTTTTTATGCAAAATCAGGGGTGGAAGGTTTTACCTTT
TCACGTATTGCTGCACACTT

Product: acid phosphatase/phosphotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MIDLGINMRKLTLALAAASLLFTLNSAVVARASTPQPLWVGTNVAQLAEQAPIHWVSVAQIENSLLGRPPMAVGFDIDDT
VLFSSPGFWRGQKTFSPGSEDYLKNPQFWEKMNNGWDEFSMPKEVARQLIAMHVKRGDSIWFVTGRSQTKTETVSKTLQD
DFLIPAANMNPVIFAGDKPGQNTKTQWLQAKQIKVFYGDSDNDITAAREAGARGIRVLRAANSSYKPLPMAGALGEEVIV
NSEY

Sequences:

>Translated_244_residues
MIDLGINMRKLTLALAAASLLFTLNSAVVARASTPQPLWVGTNVAQLAEQAPIHWVSVAQIENSLLGRPPMAVGFDIDDT
VLFSSPGFWRGQKTFSPGSEDYLKNPQFWEKMNNGWDEFSMPKEVARQLIAMHVKRGDSIWFVTGRSQTKTETVSKTLQD
DFLIPAANMNPVIFAGDKPGQNTKTQWLQAKQIKVFYGDSDNDITAAREAGARGIRVLRAANSSYKPLPMAGALGEEVIV
NSEY
>Mature_244_residues
MIDLGINMRKLTLALAAASLLFTLNSAVVARASTPQPLWVGTNVAQLAEQAPIHWVSVAQIENSLLGRPPMAVGFDIDDT
VLFSSPGFWRGQKTFSPGSEDYLKNPQFWEKMNNGWDEFSMPKEVARQLIAMHVKRGDSIWFVTGRSQTKTETVSKTLQD
DFLIPAANMNPVIFAGDKPGQNTKTQWLQAKQIKVFYGDSDNDITAAREAGARGIRVLRAANSSYKPLPMAGALGEEVIV
NSEY

Specific function: Dephosphorylates several organic phosphomonoesters and catalyzes the transfer of low-energy phosphate groups from phosphomonoesters to hydroxyl groups of various organic compounds. Preferentially acts on aryl phosphoesters. Might function as a broad-spect

COG id: COG3700

COG function: function code R; Acid phosphatase (class B)

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class B bacterial acid phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI2367341, Length=237, Percent_Identity=82.7004219409283, Blast_Score=413, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005519
- InterPro:   IPR023214
- InterPro:   IPR010025 [H]

Pfam domain/function: PF03767 Acid_phosphat_B [H]

EC number: =3.1.3.2 [H]

Molecular weight: Translated: 26860; Mature: 26860

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDLGINMRKLTLALAAASLLFTLNSAVVARASTPQPLWVGTNVAQLAEQAPIHWVSVAQ
CEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCHHHHHHHCCCEEEHHHH
IENSLLGRPPMAVGFDIDDTVLFSSPGFWRGQKTFSPGSEDYLKNPQFWEKMNNGWDEFS
HHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHCCCCCCCC
MPKEVARQLIAMHVKRGDSIWFVTGRSQTKTETVSKTLQDDFLIPAANMNPVIFAGDKPG
CHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCEEEECCCCC
QNTKTQWLQAKQIKVFYGDSDNDITAAREAGARGIRVLRAANSSYKPLPMAGALGEEVIV
CCCHHHHEEEEEEEEEECCCCCCCHHHHHCCCHHEEEEEECCCCCCCCCCCCCCCCEEEE
NSEY
ECCC
>Mature Secondary Structure
MIDLGINMRKLTLALAAASLLFTLNSAVVARASTPQPLWVGTNVAQLAEQAPIHWVSVAQ
CEECCCCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEEECCCHHHHHHHCCCEEEHHHH
IENSLLGRPPMAVGFDIDDTVLFSSPGFWRGQKTFSPGSEDYLKNPQFWEKMNNGWDEFS
HHHHHCCCCCCEEECCCCCEEEECCCCCCCCCCCCCCCCHHHHCCCHHHHHHCCCCCCCC
MPKEVARQLIAMHVKRGDSIWFVTGRSQTKTETVSKTLQDDFLIPAANMNPVIFAGDKPG
CHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCEEEECCCCCCEEEECCCCC
QNTKTQWLQAKQIKVFYGDSDNDITAAREAGARGIRVLRAANSSYKPLPMAGALGEEVIV
CCCHHHHEEEEEEEEEECCCCCCCHHHHHCCCHHEEEEEECCCCCCCCCCCCCCCCEEEE
NSEY
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9011040; 8265357; 9278503; 9298646 [H]