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The map label for this gene is plsB [H]

Identifier: 238892513

GI number: 238892513

Start: 297250

End: 299673

Strand: Reverse

Name: plsB [H]

Synonym: KP1_0281

Alternate gene names: 238892513

Gene position: 299673-297250 (Counterclockwise)

Preceding gene: 238892517

Following gene: 238892507

Centisome position: 5.71

GC content: 59.78

Gene sequence:

>2424_bases
ATGTCCGGCTGGCAACGAATTTACTATAAATTACTGAATTTACCATTACAGGTGCTGGTAAAAAGCAAGTCTATTCCGGC
AGAGCCTGCCCAGGAATTAGGACTCGATACCTCGCGTCCGGTCATGTACGTCCTGCCCTATAATTCGAAGGCGGACCTGC
TGACGCTGCGCGCCCAATGCCTGGCGCATGATTTACCTGACCCGCTTGAACCGCTGGAAATCGACGGCGCCCTGCTGCCG
CGTTACGTATTCATCCACGGTGGGCCGCGCGTATTTACTTATTACACGCCAAAAGAAGAGTCCATCAAGCTGTTCCACGA
TTACCTCGATCTGCACCGCAACCATCCGGACCTCGATGTGCAAATGGTGCCGGTTTCGGTCATGTTCGGCCGTTCGCCGG
GTCGCGAGAAAGGAGAAGTCAATCCGCCGCTGCGGATGCTGAACGGCATTCAGAAATTTTTCGCCGTCTCCTGGCTCGGC
CGCGACAGTTTCGTGCGCTTCTCGCCGTCCGTTTCGCTGCGCCGCATGGCGGATGAGCACGGTACCGATAAGATCATCGC
CCAGAAGCTGGCTCGCGTCGCTCGCATGCATTTTGCCCGCCAGCGGCTGGCCGCCGTTGGCCCGCGTCTGCCGGCCCGCC
AGGATCTGTTTAATAAACTGCTGGCCTCGAAAGCGATTGCCCGCGCGGTGGAAGACGAAGCGCGCAGCAAGAAAATTTCG
CACGAGAAGGCACAGCAGAACGCTATCGCGCTGATGGAAGAGATTGCGGCGAACTTCTCATACGAGATGATCCGCCTGAC
CGACCGCATTCTCGGCTTCACCTGGAACCGCCTGTACCAGGGCATCAACGTGCATAACGCCGAGCGCGTACGCCAGCTGG
CGCACGACGGCCATGAAATTGTCTATGTCCCCTGCCACCGCAGCCACATGGACTATCTGCTGCTCTCCTACGTCCTGTAC
CATCAGGGGCTGGTCCCTCCGCATATCGCGGCGGGCATCAACCTCAACTTCTGGCCGGCCGGACCGATCTTCCGCCGCCT
CGGCGCCTTCTTTATTCGCCGCACCTTTAAGGGCAACAAGCTCTATTCCACCGTGTTCCGCGAATACCTTGGCGAACTGT
TCAGCCGCGGCTATTCCGTGGAGTATTTCGTCGAAGGCGGCCGCTCCCGTACCGGCCGTCTGCTCGATCCGAAGACCGGT
ACGCTGTCGATGACCATCCAGGCGATGCTGCGCGGCGGAACCCGACCGATCACCCTGGTGCCGATTTACATCGGCTATGA
GCACGTGATGGAGGTAGGAACCTACGCCAAAGAGCTGCGCGGCGCCACTAAAGAGAAAGAGAGTCTGCCGCAGATGGTGC
GCGGTTTAAGCAAGCTGCGCAACCTGGGCCAGGGTTACGTTAACTTCGGCGAACCGCTGCCGCTGATGACCTATCTTAAC
CAGCATGTGCCGGATTGGCGGGAAGCGATCGACCCGATCGAAGCGGTTCGCCCCTCCTGGCTGACGCCGACGGTGAATAG
CATCGCCGCTGACCTGATGGTGCGCATCAATAACGCCGGCGCGGCCAACGCCATGAACCTGTGCTGTACGGCGCTACTGG
CCTCCCGCCAGCGTTCGCTGACCCGTGAGCAGCTCACCCAGCAGTTAGAGTGCTACCTCGCGCTGCTGCGCAATGTGCCC
TATTCTCCGGATGCGACCGCCCCATCCGCTTCGGCCAGCGAGCTCATCGATCATGCACTGCAGATGAACAAGTTCGAAGT
GGAGAAGGACACCATTGGCGACATCATCATCCTGCCGCGCGAGCAGGCGGTGCTGATGACCTACTATCGCAACAATATCG
CCCATATGCTGGTGATGCCGTCGCTGTTAGCCGCTCTGGTGACTCAGCATCGTCATCTCAGCCGCGCCGAAGTGCTGCGT
CATGTGGAAACACTCTATCCGTTCCTCAAGGCCGAGCTGTTCCTGCGCTGGGAAAAAGCGGAGCTGGCCGGAGTGGTGGA
TGCGCTGATTGCCGAGATGCTGCGTCAGGAGCTGATCGTCGTCGATGGCGATGTCATGAGCCTCAACCCGTCGCACTCTC
GCTCCCTGCAGCTGCTGGCCGCTGGCGCCCGCGAGACGCTGCAGCGCTATGCCATCACCTTCTGGCTGCTGAGCGCTAAC
CCGGCGATCAACCGCAGCTCGCTGGAAAAAGAGAGTCGCACCGTGGCCCAGCGTCTGTCGGTGCTACACGGCATCAATGC
GCCGGAGTTCTTCGACAAAGCGGTGTTCAGCACCCTGGTGTTGACCCTGCGCGATGAAGGCTATATCAGCGACACCGGCG
ACGCCGAGCCGGAAGAGACCCTGAAGGTTTATCGGATGCTGGCGGACTTGATTACGTCGGATGTCCGACTGACCATTGAG
AGCGTCACGCAGGACGACGCGTAA

Upstream 100 bases:

>100_bases
GATGAGTGTGCGCGTTTGCCGCGTGGTAACGGAAATTTTGCCCACTTTCTGTTATTCTTGCCGCGCATTTGCATGATTAA
CCAGAGGCTTCACATCGTTT

Downstream 100 bases:

>100_bases
CGCGGCGTTTGCTGCCCCCCGGAATGCCGGGGGGCAGCGGACAGGAGGTTACAGGTAGCTCATCGCCAGGCCGAGGAACA
GCACCAGCCCGACGTAGTTA

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 807; Mature: 806

Protein sequence:

>807_residues
MSGWQRIYYKLLNLPLQVLVKSKSIPAEPAQELGLDTSRPVMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLP
RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRNHPDLDVQMVPVSVMFGRSPGREKGEVNPPLRMLNGIQKFFAVSWLG
RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMVRGLSKLRNLGQGYVNFGEPLPLMTYLN
QHVPDWREAIDPIEAVRPSWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTQQLECYLALLRNVP
YSPDATAPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVMPSLLAALVTQHRHLSRAEVLR
HVETLYPFLKAELFLRWEKAELAGVVDALIAEMLRQELIVVDGDVMSLNPSHSRSLQLLAAGARETLQRYAITFWLLSAN
PAINRSSLEKESRTVAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDAEPEETLKVYRMLADLITSDVRLTIE
SVTQDDA

Sequences:

>Translated_807_residues
MSGWQRIYYKLLNLPLQVLVKSKSIPAEPAQELGLDTSRPVMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLP
RYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRNHPDLDVQMVPVSVMFGRSPGREKGEVNPPLRMLNGIQKFFAVSWLG
RDSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKIS
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLY
HQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTG
TLSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMVRGLSKLRNLGQGYVNFGEPLPLMTYLN
QHVPDWREAIDPIEAVRPSWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTQQLECYLALLRNVP
YSPDATAPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVMPSLLAALVTQHRHLSRAEVLR
HVETLYPFLKAELFLRWEKAELAGVVDALIAEMLRQELIVVDGDVMSLNPSHSRSLQLLAAGARETLQRYAITFWLLSAN
PAINRSSLEKESRTVAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDAEPEETLKVYRMLADLITSDVRLTIE
SVTQDDA
>Mature_806_residues
SGWQRIYYKLLNLPLQVLVKSKSIPAEPAQELGLDTSRPVMYVLPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGALLPR
YVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRNHPDLDVQMVPVSVMFGRSPGREKGEVNPPLRMLNGIQKFFAVSWLGR
DSFVRFSPSVSLRRMADEHGTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKISH
EKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEIVYVPCHRSHMDYLLLSYVLYH
QGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGT
LSMTIQAMLRGGTRPITLVPIYIGYEHVMEVGTYAKELRGATKEKESLPQMVRGLSKLRNLGQGYVNFGEPLPLMTYLNQ
HVPDWREAIDPIEAVRPSWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTQQLECYLALLRNVPY
SPDATAPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVMPSLLAALVTQHRHLSRAEVLRH
VETLYPFLKAELFLRWEKAELAGVVDALIAEMLRQELIVVDGDVMSLNPSHSRSLQLLAAGARETLQRYAITFWLLSANP
AINRSSLEKESRTVAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDAEPEETLKVYRMLADLITSDVRLTIES
VTQDDA

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=432, Percent_Identity=27.0833333333333, Blast_Score=152, Evalue=2e-36,
Organism=Homo sapiens, GI190358539, Length=271, Percent_Identity=32.1033210332103, Blast_Score=134, Evalue=3e-31,
Organism=Escherichia coli, GI87082362, Length=807, Percent_Identity=90.5824039653036, Blast_Score=1510, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988723, Length=575, Percent_Identity=25.5652173913043, Blast_Score=146, Evalue=6e-35,
Organism=Caenorhabditis elegans, GI25147672, Length=279, Percent_Identity=30.1075268817204, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI71988728, Length=463, Percent_Identity=26.5658747300216, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24650754, Length=513, Percent_Identity=25.7309941520468, Blast_Score=147, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357731, Length=507, Percent_Identity=25.8382642998028, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI24650752, Length=513, Percent_Identity=25.7309941520468, Blast_Score=147, Evalue=3e-35,
Organism=Drosophila melanogaster, GI17864692, Length=270, Percent_Identity=31.1111111111111, Blast_Score=145, Evalue=1e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 91293; Mature: 91162

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGWQRIYYKLLNLPLQVLVKSKSIPAEPAQELGLDTSRPVMYVLPYNSKADLLTLRAQC
CCHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRNHPDLDV
HHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCE
QMVPVSVMFGRSPGREKGEVNPPLRMLNGIQKFFAVSWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKIS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMVRGLSKLRNLGQGYVNFGEPLPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPDWREAIDPIEAVRPSWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCCCHHHHCCHHHHCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTQQLECYLALLRNVPYSPDATAPSASASELIDHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLVMPSLLAALVTQHRHLSRAEVLRHVETLYPFLKAELFLRWEKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEHHH
ELAGVVDALIAEMLRQELIVVDGDVMSLNPSHSRSLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHHHEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
PAINRSSLEKESRTVAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDAEPEET
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LKVYRMLADLITSDVRLTIESVTQDDA
HHHHHHHHHHHHCHHHEEHHHHCCCCC
>Mature Secondary Structure 
SGWQRIYYKLLNLPLQVLVKSKSIPAEPAQELGLDTSRPVMYVLPYNSKADLLTLRAQC
CHHHHHHHHHHCCCHHHHHCCCCCCCCCHHHCCCCCCCCEEEEECCCCCCHHHHHHHHH
LAHDLPDPLEPLEIDGALLPRYVFIHGGPRVFTYYTPKEESIKLFHDYLDLHRNHPDLDV
HHCCCCCCCCCCCCCCCCCCEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCE
QMVPVSVMFGRSPGREKGEVNPPLRMLNGIQKFFAVSWLGRDSFVRFSPSVSLRRMADEH
EEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEECCCHHHHHHHHHC
GTDKIIAQKLARVARMHFARQRLAAVGPRLPARQDLFNKLLASKAIARAVEDEARSKKIS
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWNRLYQGINVHNAERVRQLAHDGHEI
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCEE
VYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGINLNFWPAGPIFRRLGAFFIRRTFKGNK
EEECCCCCHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCH
LYSTVFREYLGELFSRGYSVEYFVEGGRSRTGRLLDPKTGTLSMTIQAMLRGGTRPITLV
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCEECCCCCHHHHHHHHHHCCCCCCEEEE
PIYIGYEHVMEVGTYAKELRGATKEKESLPQMVRGLSKLRNLGQGYVNFGEPLPLMTYLN
EEECCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHH
QHVPDWREAIDPIEAVRPSWLTPTVNSIAADLMVRINNAGAANAMNLCCTALLASRQRSL
HCCCCHHHHCCHHHHCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHH
TREQLTQQLECYLALLRNVPYSPDATAPSASASELIDHALQMNKFEVEKDTIGDIIILPR
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCEEEECC
EQAVLMTYYRNNIAHMLVMPSLLAALVTQHRHLSRAEVLRHVETLYPFLKAELFLRWEKA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEHHH
ELAGVVDALIAEMLRQELIVVDGDVMSLNPSHSRSLQLLAAGARETLQRYAITFWLLSAN
HHHHHHHHHHHHHHHHHEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHEEEECC
PAINRSSLEKESRTVAQRLSVLHGINAPEFFDKAVFSTLVLTLRDEGYISDTGDAEPEET
CCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
LKVYRMLADLITSDVRLTIESVTQDDA
HHHHHHHHHHHHCHHHEEHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA