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The map label for this gene is panC [H]

Identifier: 238028347

GI number: 238028347

Start: 3188481

End: 3189320

Strand: Direct

Name: panC [H]

Synonym: bglu_1g28080

Alternate gene names: 238028347

Gene position: 3188481-3189320 (Clockwise)

Preceding gene: 238028346

Following gene: 238028348

Centisome position: 81.62

GC content: 69.29

Gene sequence:

>840_bases
ATGAAAGTCATCAGCACGATCCAGGAACTGCGCGACCAGTTGCGCGGCCAGAACCGCACGGCCTTCGTGCCGACCATGGG
CAACCTGCATGACGGCCATCTGTCGCTGATGCGGCTCGCGCGCCAGCACGGCGACCCGGTGGTCGCGAGCATTTTCGTGA
ACCGGCTGCAGTTCGGCCCGAACGAGGACTTCGACAAGTATCCGCGCACGCTCGAGCAGGACATCGAGAAGCTGCAGAAG
GAAAACGTCTACGTGCTGTTCGCGCCCACCGAGCGCGACCTCTATCCGGAGCCGCAGGAATATCGCGTGCAGCCGCCGCA
CGACCTCGGCGACATCCTGGAGGGCGAGTTCCGCCCCGGCTTCTTCACCGGGGTGTGCACCGTGGTCACCAAGCTGATGG
CCTGCGTGTCGCCCAAGGTGGCCGTGTTCGGCAAGAAGGATTACCAGCAGCTGATGATCGTGCGCCGCATGTGCCATCAG
CTCGCGCTGCCGGTGGAGATCGTCGCCGCCGAGACGGTGCGCGACGACGACGGCCTCGCGATGTCCTCGCGCAACCGCTT
CCTGAGCCCGGCCGAGCGCGCCGAGGCGCCGCAGCTCGCGCGTGCGCTGCAGCGCGTGCGCGAGAGCGTGCTTGGCGGCG
AGCGCGACCTCGCGGCCGTCGAGGCGCGCGCGCGCGAGGCGCTGGCCGCGCGCGGCTGGCAGCCCGACTATGTCGCGGTG
CGCCGCCGCGCCAATCTGGTGGCGCCGAGCGCCGCCCAGCTCGAAGCCGGCGAGCCGCTGGTGGTGCTGGCGGCCGCCAA
GCTCGGCACCACGCGCCTCATCGACAATCTCGAGATCTGA

Upstream 100 bases:

>100_bases
GCCGCCGTGCGCCGCACCGGGCGAGCGACACCTCCGATCACGACGCCGCGCCAGACGCGGCGGCAACGCGCGAGACGCGC
GAGGAACCGCCTGACCGATC

Downstream 100 bases:

>100_bases
CGGCCCGCCGGCCGCGATCCCGCCAACCCACGCCAGGAAACGCCATGCAGCGCCACATGCTGAAATCGAAGATCCACCGT
GCCACGGTCACGCACTGCGA

Product: pantoate--beta-alanine ligase

Products: NA

Alternate protein names: PS; Pantoate--beta-alanine ligase; Pantoate-activating enzyme [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MKVISTIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLEQDIEKLQK
ENVYVLFAPTERDLYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVSPKVAVFGKKDYQQLMIVRRMCHQ
LALPVEIVAAETVRDDDGLAMSSRNRFLSPAERAEAPQLARALQRVRESVLGGERDLAAVEARAREALAARGWQPDYVAV
RRRANLVAPSAAQLEAGEPLVVLAAAKLGTTRLIDNLEI

Sequences:

>Translated_279_residues
MKVISTIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLEQDIEKLQK
ENVYVLFAPTERDLYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVSPKVAVFGKKDYQQLMIVRRMCHQ
LALPVEIVAAETVRDDDGLAMSSRNRFLSPAERAEAPQLARALQRVRESVLGGERDLAAVEARAREALAARGWQPDYVAV
RRRANLVAPSAAQLEAGEPLVVLAAAKLGTTRLIDNLEI
>Mature_279_residues
MKVISTIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGPNEDFDKYPRTLEQDIEKLQK
ENVYVLFAPTERDLYPEPQEYRVQPPHDLGDILEGEFRPGFFTGVCTVVTKLMACVSPKVAVFGKKDYQQLMIVRRMCHQ
LALPVEIVAAETVRDDDGLAMSSRNRFLSPAERAEAPQLARALQRVRESVLGGERDLAAVEARAREALAARGWQPDYVAV
RRRANLVAPSAAQLEAGEPLVVLAAAKLGTTRLIDNLEI

Specific function: Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate [H]

COG id: COG0414

COG function: function code H; Panthothenate synthetase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pantothenate synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786325, Length=282, Percent_Identity=42.9078014184397, Blast_Score=215, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6322046, Length=310, Percent_Identity=35.1612903225806, Blast_Score=156, Evalue=3e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004821
- InterPro:   IPR003721
- InterPro:   IPR014729 [H]

Pfam domain/function: PF02569 Pantoate_ligase [H]

EC number: =6.3.2.1 [H]

Molecular weight: Translated: 31222; Mature: 31222

Theoretical pI: Translated: 7.05; Mature: 7.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVISTIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGP
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLEQDIEKLQKENVYVLFAPTERDLYPEPQEYRVQPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCC
FFTGVCTVVTKLMACVSPKVAVFGKKDYQQLMIVRRMCHQLALPVEIVAAETVRDDDGLA
HHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
MSSRNRFLSPAERAEAPQLARALQRVRESVLGGERDLAAVEARAREALAARGWQPDYVAV
ECCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RRRANLVAPSAAQLEAGEPLVVLAAAKLGTTRLIDNLEI
HHHHCCCCCCHHHHCCCCCEEEEEEHHHCHHHHHHCCCC
>Mature Secondary Structure
MKVISTIQELRDQLRGQNRTAFVPTMGNLHDGHLSLMRLARQHGDPVVASIFVNRLQFGP
CCHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHCCC
NEDFDKYPRTLEQDIEKLQKENVYVLFAPTERDLYPEPQEYRVQPPHDLGDILEGEFRPG
CCCHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHCCCCCCCCHHHHHCCCCCCC
FFTGVCTVVTKLMACVSPKVAVFGKKDYQQLMIVRRMCHQLALPVEIVAAETVRDDDGLA
HHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCE
MSSRNRFLSPAERAEAPQLARALQRVRESVLGGERDLAAVEARAREALAARGWQPDYVAV
ECCCCCCCCCHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
RRRANLVAPSAAQLEAGEPLVVLAAAKLGTTRLIDNLEI
HHHHCCCCCCHHHHCCCCCEEEEEEHHHCHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA