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The map label for this gene is nuoD [H]

Identifier: 238028140

GI number: 238028140

Start: 2954554

End: 2955807

Strand: Reverse

Name: nuoD [H]

Synonym: bglu_1g25910

Alternate gene names: 238028140

Gene position: 2955807-2954554 (Counterclockwise)

Preceding gene: 238028141

Following gene: 238028139

Centisome position: 75.66

GC content: 61.4

Gene sequence:

>1254_bases
ATGGCTGACATCAAGAACTACACGCTCAACTTCGGCCCCCAGCACCCGGCCGCGCACGGCGTGCTGCGACTCGTGCTCGA
GCTCGACGGCGAGGTGATCCAGCGTGCCGATCCGCACATCGGCCTGCTGCACCGCGCGACCGAGAAGCTCGCCGAGAACA
AGACCTTCATCCAGTCGGTGCCGTACATGGACCGTCTCGACTATGTGTCGATGATGGCGAACGAACACGGCTACGTGCTT
GCGATCGAGAAACTGCTCGGTATCGACGTGCCGGAGCGCGCGCAGTATATCCGCGTGCTGTTCGACGAGATCACGCGCGT
GCTGAACCACCTGATGTGGATCGGCTCGCACGGTCTCGACGTCGGTGCGATGGCGGTGTTCCTCTACGCGTTCCGCGAGC
GCGAGGACCTGATGGACGTCTACGAGGCGGTCTCCGGCGCGCGCATGCACGCGGCCTACTACCGCCCGGGCGGCGTGTAT
CGCGACCTGCCTGACGTGATGCCGCAATACAAGGCATCGAAGATTCGCAACGAGAAGGCGCTGTCGAAGATGAACGAGGC
GCGCCAGGGTTCGGTGCTCGACTTCATCGACGATTTCTTCACGCGCTTTCCGAAGTGTGTCGACGAATACGAAACGTTGC
TGACCGACAATCGGATCTGGAAGCAGCGTCTCGTCGGGATCGGTGTGGTGAGTCCCGAACGCGCGCTGCAGCTCGGCCTG
ACGGGCGCGATGCTGCGCGGCTCCGGAATCGAGTGGGACCTGCGCAAGAAGCAGCCCTACGAAGTGTATGACCGCCTCGA
TTTCGACATCCCGGTCGGGGTGAACGGCGATTGCTACGACCGTTATCTGGTTCGCGTCGAGGAGATGCGGCAGTCGTGCC
GCATCGCGAAACAGTGTATTGAGTGGCTGCGGAAGAATCCGGGTCCGGTGATGACGGACAATCACAAGATTGCGCCGCCC
AAACGTGTCGACATGAAGTCGAACATGGAAGATCTGATTCACCACTTCAAGCTGTTCACCGAAGGTTTCCATGTGCCGGA
AGGCGAAACCTACGCGGCGGTCGAGCACCCGAAGGGCGAATTCGGCATCTATCTCGTGTCCGACGGCGCGAACAAGCCAT
ACCGGCTGAAGATTCGCGCGCCCGGCTACGCGCATCTCTCCGCGCTCAACGAAATGGCGCATGGCCACATGATTGCCGAC
GCGGTCACGATCATCGGTACGCAGGACATCGTGTTCGGCGAAATCGACCGCTGA

Upstream 100 bases:

>100_bases
GCGCGTCGTCTACCAGCCCGTGACGATCGAACCCCGCGAGATCACGCCGCGCGTGATCCGCGAGGATCGGTACGGCGGTC
TGAAACATTGAGAGGGCGAC

Downstream 100 bases:

>100_bases
TCGCCACGCCGCCCGCGTCGAGCGGGCGGCGGGCAGCCAACAGTGAGCGCCAGGTCTGCCGTTGCGCATCCCGCGGCAGG
TTGTTCGTTCGGTAGGAATT

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMANEHGYVL
AIEKLLGIDVPERAQYIRVLFDEITRVLNHLMWIGSHGLDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDVMPQYKASKIRNEKALSKMNEARQGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
TGAMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSCRIAKQCIEWLRKNPGPVMTDNHKIAPP
KRVDMKSNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALNEMAHGHMIAD
AVTIIGTQDIVFGEIDR

Sequences:

>Translated_417_residues
MADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMANEHGYVL
AIEKLLGIDVPERAQYIRVLFDEITRVLNHLMWIGSHGLDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVY
RDLPDVMPQYKASKIRNEKALSKMNEARQGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
TGAMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSCRIAKQCIEWLRKNPGPVMTDNHKIAPP
KRVDMKSNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALNEMAHGHMIAD
AVTIIGTQDIVFGEIDR
>Mature_416_residues
ADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSVPYMDRLDYVSMMANEHGYVLA
IEKLLGIDVPERAQYIRVLFDEITRVLNHLMWIGSHGLDVGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYR
DLPDVMPQYKASKIRNEKALSKMNEARQGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGLT
GAMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSCRIAKQCIEWLRKNPGPVMTDNHKIAPPK
RVDMKSNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGEFGIYLVSDGANKPYRLKIRAPGYAHLSALNEMAHGHMIADA
VTIIGTQDIVFGEIDR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=414, Percent_Identity=60.3864734299517, Blast_Score=517, Evalue=1e-147,
Organism=Homo sapiens, GI260898743, Length=408, Percent_Identity=59.5588235294118, Blast_Score=501, Evalue=1e-142,
Organism=Escherichia coli, GI145693162, Length=410, Percent_Identity=38.0487804878049, Blast_Score=298, Evalue=5e-82,
Organism=Escherichia coli, GI1789076, Length=418, Percent_Identity=28.2296650717703, Blast_Score=134, Evalue=8e-33,
Organism=Escherichia coli, GI1788832, Length=408, Percent_Identity=26.9607843137255, Blast_Score=112, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17555284, Length=416, Percent_Identity=58.6538461538462, Blast_Score=499, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17568379, Length=416, Percent_Identity=57.4519230769231, Blast_Score=494, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24638644, Length=415, Percent_Identity=59.7590361445783, Blast_Score=523, Evalue=1e-149,
Organism=Drosophila melanogaster, GI221459469, Length=412, Percent_Identity=55.5825242718447, Blast_Score=469, Evalue=1e-132,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR014029
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 47627; Mature: 47496

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00535 COMPLEX1_49K

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSV
CCCCCCCEECCCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHC
PYMDRLDYVSMMANEHGYVLAIEKLLGIDVPERAQYIRVLFDEITRVLNHLMWIGSHGLD
CCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDVMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LSKMNEARQGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGAMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSCRIAKQCI
CHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKIAPPKRVDMKSNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGYAHLSALNEMAHGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCC
>Mature Secondary Structure 
ADIKNYTLNFGPQHPAAHGVLRLVLELDGEVIQRADPHIGLLHRATEKLAENKTFIQSV
CCCCCCEECCCCCCCHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHC
PYMDRLDYVSMMANEHGYVLAIEKLLGIDVPERAQYIRVLFDEITRVLNHLMWIGSHGLD
CCHHHHHHHHHHHCCCCEEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VGAMAVFLYAFREREDLMDVYEAVSGARMHAAYYRPGGVYRDLPDVMPQYKASKIRNEKA
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHH
LSKMNEARQGSVLDFIDDFFTRFPKCVDEYETLLTDNRIWKQRLVGIGVVSPERALQLGL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCHHHHHHHCC
TGAMLRGSGIEWDLRKKQPYEVYDRLDFDIPVGVNGDCYDRYLVRVEEMRQSCRIAKQCI
CHHHHCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
EWLRKNPGPVMTDNHKIAPPKRVDMKSNMEDLIHHFKLFTEGFHVPEGETYAAVEHPKGE
HHHHCCCCCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCC
FGIYLVSDGANKPYRLKIRAPGYAHLSALNEMAHGHMIADAVTIIGTQDIVFGEIDR
EEEEEEECCCCCCEEEEEECCCHHHHHHHHHHHCCHHHHHHHHHCCCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA