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The map label for this gene is nuoH [H]

Identifier: 238028136

GI number: 238028136

Start: 2949140

End: 2950204

Strand: Reverse

Name: nuoH [H]

Synonym: bglu_1g25870

Alternate gene names: 238028136

Gene position: 2950204-2949140 (Counterclockwise)

Preceding gene: 238028137

Following gene: 238028135

Centisome position: 75.52

GC content: 63.38

Gene sequence:

>1065_bases
ATGAGCTTGTTCGATACGATCAACTCGAACGGTACCGCGCTGCTCGGCGCGGCATGGCCGACCGTATGGGCGCTCGTGCG
CATCCTCGTGGTCGCCGTGGTGATCCTGCTCTGCGTCGCGTACCTGATCCTCTGGGAGCGCAAGCTGATCGGCTGGATGC
ACGTGCGGCTCGGCCCGAACCGCGTCGGTCCCGGCGGCCTGCTGCAGCCGATCGCCGACGTGCTGAAGCTGCTGCTGAAG
GAGGTGATCCAGCCGACCGCGGCGAGCCGCTGGTTGTACCTGATCGCGCCGGTGATGACGGTGGTGCCGGCATTCGCGGT
CTGGGCGGTGATTCCGTTCCAGGCCGGCGCGGTGCTCGCCAACATCAACGCGGGCCTGCTCTACGCGATGGCGATCTCGT
CGATCGGCGTGTACGCGGTGATCCTGGCCGGCTGGGCCTCGAATTCGAAGTACGCGTTCCTTGGCGCGATGCGCGCGGCC
GCGCAGATGGTGTCGTATGAAATCTCGATGGGCTTCGCGCTGGTGCTGGTGCTGATGACGGCCGGCAGCCTGAACCTCTC
CGAGATCGTCGCCTCGCAGCAGCACGGCTATTTCGCACACCACGGCATCAACTTCATGTCGTGGAACTGGCTGCCGCTGC
TGCCGGTGTTCGTCATCTACTTCATCTCGGGCATCGCGGAAACGAACCGCCACCCGTTCGACGTGGTGGAAGGCGAGTCG
GAAATCGTGGCCGGCCACATGATCGACTACTCGGGGATGGGCTTCGCGCTGTTCTTCCTCGCCGAGTACATCAACATGAT
CGTGATCTCGGCGCTGGCCGCCACGCTGTTCCTCGGCGGTTGGGACTCACCGTTCAGCTTCCTGTCGTTCATCCCGGGCA
TCGTCTGGCTCGTGGCGAAAGTCTTTTTCCTGCTGTCGGTGTTCATCTGGGCCCGCGCGACGTTCCCGCGCTTCCGTTAC
GACCAGATCATGCGTCTTGGCTGGAAGATCTTCCTGCCGATCTGCGTGATCTGGGTGGTGGTGGTCGGCTTCTGGATGAT
GTCGCCGCTGAATATCTGGAATTGA

Upstream 100 bases:

>100_bases
TGCGAATCTGGCCGAGACGGTGGTTCGCGTATCGGCCGCCACGCCCGCCGGTGCGGTACTCGGCGGCCAGTCAGGTGAAC
TCGTGGTGGAGAAGGCGTAA

Downstream 100 bases:

>100_bases
GAGGGCGGATACCATCATGACGGCAATCCAACATTTCTTTAAGACCTTCTTCCTGACCGAACTGCTCAAGGGGCTGGCGC
TGACGGGACGCTATACGTTC

Product: NADH:ubiquinone oxidoreductase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 354; Mature: 353

Protein sequence:

>354_residues
MSLFDTINSNGTALLGAAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPTAASRWLYLIAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVASQQHGYFAHHGINFMSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMGFALFFLAEYINMIVISALAATLFLGGWDSPFSFLSFIPGIVWLVAKVFFLLSVFIWARATFPRFRY
DQIMRLGWKIFLPICVIWVVVVGFWMMSPLNIWN

Sequences:

>Translated_354_residues
MSLFDTINSNGTALLGAAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLK
EVIQPTAASRWLYLIAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAA
AQMVSYEISMGFALVLVLMTAGSLNLSEIVASQQHGYFAHHGINFMSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
EIVAGHMIDYSGMGFALFFLAEYINMIVISALAATLFLGGWDSPFSFLSFIPGIVWLVAKVFFLLSVFIWARATFPRFRY
DQIMRLGWKIFLPICVIWVVVVGFWMMSPLNIWN
>Mature_353_residues
SLFDTINSNGTALLGAAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPNRVGPGGLLQPIADVLKLLLKE
VIQPTAASRWLYLIAPVMTVVPAFAVWAVIPFQAGAVLANINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAA
QMVSYEISMGFALVLVLMTAGSLNLSEIVASQQHGYFAHHGINFMSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGESE
IVAGHMIDYSGMGFALFFLAEYINMIVISALAATLFLGGWDSPFSFLSFIPGIVWLVAKVFFLLSVFIWARATFPRFRYD
QIMRLGWKIFLPICVIWVVVVGFWMMSPLNIWN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=299, Percent_Identity=43.1438127090301, Blast_Score=254, Evalue=9e-68,
Organism=Escherichia coli, GI1788618, Length=319, Percent_Identity=41.3793103448276, Blast_Score=261, Evalue=4e-71,
Organism=Escherichia coli, GI1789077, Length=282, Percent_Identity=25.177304964539, Blast_Score=66, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 39186; Mature: 39055

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLFDTINSNGTALLGAAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPTAASRWLYLIAPVMTVVPAFAVWAVIPFQAGAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVASQQHGYFAHHGINFMSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
CCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMGFALFFLAEYINMIVISALAATLFLGGWDSPFSFLSFIPGIVWLVAK
CEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFFLLSVFIWARATFPRFRYDQIMRLGWKIFLPICVIWVVVVGFWMMSPLNIWN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLFDTINSNGTALLGAAWPTVWALVRILVVAVVILLCVAYLILWERKLIGWMHVRLGPN
CCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCC
RVGPGGLLQPIADVLKLLLKEVIQPTAASRWLYLIAPVMTVVPAFAVWAVIPFQAGAVLA
CCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
NINAGLLYAMAISSIGVYAVILAGWASNSKYAFLGAMRAAAQMVSYEISMGFALVLVLMT
ECCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGSLNLSEIVASQQHGYFAHHGINFMSWNWLPLLPVFVIYFISGIAETNRHPFDVVEGES
CCCCCHHHHHHHHCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEECCCC
EIVAGHMIDYSGMGFALFFLAEYINMIVISALAATLFLGGWDSPFSFLSFIPGIVWLVAK
CEEEHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHH
VFFLLSVFIWARATFPRFRYDQIMRLGWKIFLPICVIWVVVVGFWMMSPLNIWN
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA