Click here to switch to the map view.

The map label for this gene is lpsI [H]

Identifier: 238027736

GI number: 238027736

Start: 2345763

End: 2346467

Strand: Reverse

Name: lpsI [H]

Synonym: bglu_1g21570

Alternate gene names: 238027736

Gene position: 2346467-2345763 (Counterclockwise)

Preceding gene: 238027738

Following gene: 238027735

Centisome position: 60.07

GC content: 66.1

Gene sequence:

>705_bases
ATGAACAAGATCTACCCAAGCGCGGCGGCCGCGCTCGAGGGCGTCGTCGCGGACGGCCAGATGTTCGCGGTCGGCGGCTT
CGGCCTGTGCGGAATTCCGGAGGCGCTGATCGCGGCTCTGCGCGACTCCGGCGTCAAGAACATCACCTGCATCAGCAACA
ACGCGGGCGTGGACGGCTTCGGCCTCGGCCTGCTGCTGGAGACGCGGCAGATCAGGAAGATGATCTCGTCCTACGTCGGC
GAGAACAAGGAGTTCGAGCGCCAGTACCTGGCCGGCGAACTCGAGCTGGAATTCACGCCGCAGGGCACGCTGGCCGAGAA
GCTGCGCGCGGGCGGCGCCGGCATTCCGGCGTTCTTCACCAACACGGGCTACGGCACCGTGATCGCGGAAGGCAAGGAAA
CGCGCCAGTTCGGCGACAAGCACTACGTGCTGGAGCCGTCGCTGACGGCCGACGTCGCGCTCGTCAAGGCCTGGAAGGCC
GACAAGTCCGGCAACCTGATCTACCGCCGCACCGCGCGCAACTTCAACCCGATGTGCGCGATGGCCGGCCGCATCACCGT
GGCGGAGGTCGAGGAGATCGTCGAGAACGGCGAACTGGATCCGGATCAGATCCACACGCCGGGCATCTTCGTGCAGCGCC
TGGTGCTGAACGCCACCCCGGAAAAACGCATCGAACAACGCGTCGTGCGCGCGAAAGGAGACTGA

Upstream 100 bases:

>100_bases
TCAGCGGGGCGTCATCCGTGCGTGACTAGAATGGCGCGAACCGTTTCGCCGCGCGTCGCGAACCGGTTCGACTGTTTTCC
ATAGAGGAAGGGACAGAAAC

Downstream 100 bases:

>100_bases
GATGGCCTGGAATCGTGACCAGATGGCCGCGCGCGCGGCGCAGGAACTGCAGGACGGCTTCTACGTGAACCTCGGCATCG
GGCTGCCGACGCTGGTGGCC

Product: 3-oxoacid CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MNKIYPSAAAALEGVVADGQMFAVGGFGLCGIPEALIAALRDSGVKNITCISNNAGVDGFGLGLLLETRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDKHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGRITVAEVEEIVENGELDPDQIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Sequences:

>Translated_234_residues
MNKIYPSAAAALEGVVADGQMFAVGGFGLCGIPEALIAALRDSGVKNITCISNNAGVDGFGLGLLLETRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDKHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGRITVAEVEEIVENGELDPDQIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
>Mature_234_residues
MNKIYPSAAAALEGVVADGQMFAVGGFGLCGIPEALIAALRDSGVKNITCISNNAGVDGFGLGLLLETRQIRKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFTNTGYGTVIAEGKETRQFGDKHYVLEPSLTADVALVKAWKA
DKSGNLIYRRTARNFNPMCAMAGRITVAEVEEIVENGELDPDQIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=252, Percent_Identity=55.5555555555556, Blast_Score=280, Evalue=7e-76,
Organism=Homo sapiens, GI11545841, Length=238, Percent_Identity=52.9411764705882, Blast_Score=238, Evalue=3e-63,
Organism=Escherichia coli, GI1788551, Length=204, Percent_Identity=44.1176470588235, Blast_Score=185, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17531517, Length=252, Percent_Identity=54.3650793650794, Blast_Score=263, Evalue=6e-71,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=53.6, Blast_Score=250, Evalue=6e-67,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=53.6, Blast_Score=250, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25293; Mature: 25293

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKIYPSAAAALEGVVADGQMFAVGGFGLCGIPEALIAALRDSGVKNITCISNNAGVDGF
CCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
GLGLLLETRQIRKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEEE
NTGYGTVIAEGKETRQFGDKHYVLEPSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGRITVAEVEEIVENGELDPDQIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKIYPSAAAALEGVVADGQMFAVGGFGLCGIPEALIAALRDSGVKNITCISNNAGVDGF
CCCCCCHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCC
GLGLLLETRQIRKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGAGIPAFFT
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCCEEE
NTGYGTVIAEGKETRQFGDKHYVLEPSLTADVALVKAWKADKSGNLIYRRTARNFNPMCA
CCCCEEEEECCHHHHHCCCCEEEECCCCHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGRITVAEVEEIVENGELDPDQIHTPGIFVQRLVLNATPEKRIEQRVVRAKGD
HCCCEEHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]