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The map label for this gene is pgi [H]

Identifier: 238026982

GI number: 238026982

Start: 1493985

End: 1495607

Strand: Reverse

Name: pgi [H]

Synonym: bglu_1g13590

Alternate gene names: 238026982

Gene position: 1495607-1493985 (Counterclockwise)

Preceding gene: 238026983

Following gene: 238026980

Centisome position: 38.29

GC content: 68.45

Gene sequence:

>1623_bases
ATGACGCTGAATTCGCTCCCCGCTTGGCCTGCCCTCCAATCGCACTACGACGAGATCCGCGACGCGCAGCTGCGCGACTG
GTTTGCCGCCGGCAATGATCCGGCCCCGACGCGCGCCGAACGCTTCACGTTCAGCGGCGGCGGGCTTGCGATCGACTTCT
CGAAGAACCGCATCACCGACGCCACGCTGACGCTGCTCGTGCAGCTCGCGCGCGAGGCCGGCGTCGAGGCGCGTCGCGAC
GCGATGTTCGCCGGCGACGTGGTGAACCCGACCGAAGGCCGCGCCGCCCTGCACACCGCGCTGCGCGCGAGCGCGCCCGA
TGCGCCGTTCCACGCGCAGGTGCTGGCCGAGCGCAGCAAGATGGCCGCCTTCGCCGAGCAGGTGCGTGACGGCCGCTGGA
CCGGCTACACCGGCAAACGCATCCGCCACGTGATCAACATCGGCATCGGGGGCTCCGATCTCGGGCCGAAGATGGTGGTG
CACGCGCTCGACCATCTCGCCACGCGCGAGCTGTCGTGCGCCTTCGTCTCGAACGTGGACGGCGCCGACCTGTCGCGCGC
GCTCGAATTCTGCGATCCCGAGCAAACGCTCGTCATCGTGGTGTCGAAGACCTTCACGACGCTCGAGACCATGACCAACG
CACGCTCGGCGCGCGACTGGCTGATCTCGCACGGCTGCCCCGAGAACGCGCTCGCCAAGCACTTCGTCGGCGTGTCGGCG
AATCCCGGCGAAGTCGTGAAGTTCGGCATCGACGCCCACAACGTGTTCGAGATGTGGGACTGGGTCGGCGGGCGCTACTC
GCTGTGGTCGGCGGTGGGCCTGTCGATCATGATCGCGATCGGGCCGCAGCAGTTCGACGAGCTGCTGGCCGGCGCCAACG
AGATGGACACGCACTTTCGCGAGGCGCCGCTCGAATCGAACCTGCCGGTGCTGCTCGGCCTGATCGGCATCTGGTATCGC
AACTTCTTCGGCTCGCAGAGCTACCTGGTGGCGCCGTATTCCGAGGCGCTGCACTTCCTGCCGTCGTACCTGCAGCAGCT
GGAAATGGAGAGCAACGGCAAATCGGCGCGGCTCGACGGCGCGTTCGTCGACTACCCGACCTCGGCCGTGACCTGGGGCG
AGCCCGGCACCAACGGCCAGCACGCGTTCTTCCAGATGCTGCACCAGGGCCCGACGATCGTGCCGATCGACTTCATCGCG
GTGCTCAAGCCCGAGCATGCGCTGGCGAGCCACCATCCGAAGCTGCTCGCGAACTGCTTCGCGCAGAGCGAGGCGCTGAT
GCTCGGCCGCACGCTCGAGGAGGCGCGCAGGATCGCCGGCCCGGACAAGCCCGAACTCGCGCCGCACCTGACGTTCCCCG
GCAACCGGCCGAGCTCCACGATCCTCGTCGAGGCGCTCACGGCGCGCGCGCTGGGCGCGCTGATCGCGCTCTACGAGCAC
AAGGTGCTGGTGCAGGCCTCGATCTGGAACATCAATCCGTTCGACCAGTGGGGCGTGGAGCTCGGCAAGATTCTCGGCAA
GGTGGTCGAGGCCGACCTGAACGCCGCGAGCGTCGATGCGGGCAAGCACGATTCGTCGACCTCGGCGCTGATCGCGCGGG
CGCGCGCCGCGCTCGAGCGCTGA

Upstream 100 bases:

>100_bases
CCGAGAGGGCTCGCGCGCGGTTTCCGCGGTCCCCCGGCGTCCGGCGCCGGGCGCGATCCCGTCCTCGCCCCCGAATCACG
CTAGCTTCGCCCGAACCGAT

Downstream 100 bases:

>100_bases
GCGGCGCGCGTCGCAAAACGGCAGGATGACCGGCCGTTCTCGTTTCGCCGCTGCGGTGGCGCGGCGCGGGTCGCGACGGC
TCAGCTCGCGCTGCGCTCGG

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 540; Mature: 539

Protein sequence:

>540_residues
MTLNSLPAWPALQSHYDEIRDAQLRDWFAAGNDPAPTRAERFTFSGGGLAIDFSKNRITDATLTLLVQLAREAGVEARRD
AMFAGDVVNPTEGRAALHTALRASAPDAPFHAQVLAERSKMAAFAEQVRDGRWTGYTGKRIRHVINIGIGGSDLGPKMVV
HALDHLATRELSCAFVSNVDGADLSRALEFCDPEQTLVIVVSKTFTTLETMTNARSARDWLISHGCPENALAKHFVGVSA
NPGEVVKFGIDAHNVFEMWDWVGGRYSLWSAVGLSIMIAIGPQQFDELLAGANEMDTHFREAPLESNLPVLLGLIGIWYR
NFFGSQSYLVAPYSEALHFLPSYLQQLEMESNGKSARLDGAFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIA
VLKPEHALASHHPKLLANCFAQSEALMLGRTLEEARRIAGPDKPELAPHLTFPGNRPSSTILVEALTARALGALIALYEH
KVLVQASIWNINPFDQWGVELGKILGKVVEADLNAASVDAGKHDSSTSALIARARAALER

Sequences:

>Translated_540_residues
MTLNSLPAWPALQSHYDEIRDAQLRDWFAAGNDPAPTRAERFTFSGGGLAIDFSKNRITDATLTLLVQLAREAGVEARRD
AMFAGDVVNPTEGRAALHTALRASAPDAPFHAQVLAERSKMAAFAEQVRDGRWTGYTGKRIRHVINIGIGGSDLGPKMVV
HALDHLATRELSCAFVSNVDGADLSRALEFCDPEQTLVIVVSKTFTTLETMTNARSARDWLISHGCPENALAKHFVGVSA
NPGEVVKFGIDAHNVFEMWDWVGGRYSLWSAVGLSIMIAIGPQQFDELLAGANEMDTHFREAPLESNLPVLLGLIGIWYR
NFFGSQSYLVAPYSEALHFLPSYLQQLEMESNGKSARLDGAFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIA
VLKPEHALASHHPKLLANCFAQSEALMLGRTLEEARRIAGPDKPELAPHLTFPGNRPSSTILVEALTARALGALIALYEH
KVLVQASIWNINPFDQWGVELGKILGKVVEADLNAASVDAGKHDSSTSALIARARAALER
>Mature_539_residues
TLNSLPAWPALQSHYDEIRDAQLRDWFAAGNDPAPTRAERFTFSGGGLAIDFSKNRITDATLTLLVQLAREAGVEARRDA
MFAGDVVNPTEGRAALHTALRASAPDAPFHAQVLAERSKMAAFAEQVRDGRWTGYTGKRIRHVINIGIGGSDLGPKMVVH
ALDHLATRELSCAFVSNVDGADLSRALEFCDPEQTLVIVVSKTFTTLETMTNARSARDWLISHGCPENALAKHFVGVSAN
PGEVVKFGIDAHNVFEMWDWVGGRYSLWSAVGLSIMIAIGPQQFDELLAGANEMDTHFREAPLESNLPVLLGLIGIWYRN
FFGSQSYLVAPYSEALHFLPSYLQQLEMESNGKSARLDGAFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAV
LKPEHALASHHPKLLANCFAQSEALMLGRTLEEARRIAGPDKPELAPHLTFPGNRPSSTILVEALTARALGALIALYEHK
VLVQASIWNINPFDQWGVELGKILGKVVEADLNAASVDAGKHDSSTSALIARARAALER

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Homo sapiens, GI18201905, Length=540, Percent_Identity=48.1481481481481, Blast_Score=503, Evalue=1e-142,
Organism=Homo sapiens, GI296080693, Length=540, Percent_Identity=44.2592592592593, Blast_Score=446, Evalue=1e-125,
Organism=Escherichia coli, GI1790457, Length=543, Percent_Identity=49.9079189686924, Blast_Score=510, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI71996708, Length=551, Percent_Identity=46.0980036297641, Blast_Score=479, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71996703, Length=551, Percent_Identity=46.0980036297641, Blast_Score=479, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6319673, Length=542, Percent_Identity=46.6789667896679, Blast_Score=498, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24651916, Length=550, Percent_Identity=47.8181818181818, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI24651914, Length=550, Percent_Identity=47.8181818181818, Blast_Score=502, Evalue=1e-142,
Organism=Drosophila melanogaster, GI17737445, Length=550, Percent_Identity=47.8181818181818, Blast_Score=502, Evalue=1e-142,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR023096
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 58813; Mature: 58682

Theoretical pI: Translated: 6.11; Mature: 6.11

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLNSLPAWPALQSHYDEIRDAQLRDWFAAGNDPAPTRAERFTFSGGGLAIDFSKNRITD
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCEEEEECCCCCHH
ATLTLLVQLAREAGVEARRDAMFAGDVVNPTEGRAALHTALRASAPDAPFHAQVLAERSK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
MAAFAEQVRDGRWTGYTGKRIRHVINIGIGGSDLGPKMVVHALDHLATRELSCAFVSNVD
HHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCC
GADLSRALEFCDPEQTLVIVVSKTFTTLETMTNARSARDWLISHGCPENALAKHFVGVSA
CHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
NPGEVVKFGIDAHNVFEMWDWVGGRYSLWSAVGLSIMIAIGPQQFDELLAGANEMDTHFR
CCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHHHHHHHCCCCHHHHHHH
EAPLESNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHFLPSYLQQLEMESNGKSARLDG
HCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECC
AFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLKPEHALASHHPKLLANCF
CEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHCCHHHHHHHH
AQSEALMLGRTLEEARRIAGPDKPELAPHLTFPGNRPSSTILVEALTARALGALIALYEH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
KVLVQASIWNINPFDQWGVELGKILGKVVEADLNAASVDAGKHDSSTSALIARARAALER
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TLNSLPAWPALQSHYDEIRDAQLRDWFAAGNDPAPTRAERFTFSGGGLAIDFSKNRITD
CCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHEEEECCCCEEEEECCCCCHH
ATLTLLVQLAREAGVEARRDAMFAGDVVNPTEGRAALHTALRASAPDAPFHAQVLAERSK
HHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
MAAFAEQVRDGRWTGYTGKRIRHVINIGIGGSDLGPKMVVHALDHLATRELSCAFVSNVD
HHHHHHHHHCCCCCCCCHHHHHHHHEECCCCCCCCHHHHHHHHHHHHHHHHHHHEECCCC
GADLSRALEFCDPEQTLVIVVSKTFTTLETMTNARSARDWLISHGCPENALAKHFVGVSA
CHHHHHHHHHCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCC
NPGEVVKFGIDAHNVFEMWDWVGGRYSLWSAVGLSIMIAIGPQQFDELLAGANEMDTHFR
CCCCEEEEECCHHHHHHHHHHCCCCHHHHHHHCCEEEEEECHHHHHHHHCCCCHHHHHHH
EAPLESNLPVLLGLIGIWYRNFFGSQSYLVAPYSEALHFLPSYLQQLEMESNGKSARLDG
HCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHCCCCCCEEECC
AFVDYPTSAVTWGEPGTNGQHAFFQMLHQGPTIVPIDFIAVLKPEHALASHHPKLLANCF
CEEECCCCEEECCCCCCCCHHHHHHHHHCCCCEEEEHHHHHCCCCHHHHHCCHHHHHHHH
AQSEALMLGRTLEEARRIAGPDKPELAPHLTFPGNRPSSTILVEALTARALGALIALYEH
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHC
KVLVQASIWNINPFDQWGVELGKILGKVVEADLNAASVDAGKHDSSTSALIARARAALER
EEEEEEEECCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA