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The map label for this gene is phoB [H]

Identifier: 238026792

GI number: 238026792

Start: 1262176

End: 1262883

Strand: Direct

Name: phoB [H]

Synonym: bglu_1g11500

Alternate gene names: 238026792

Gene position: 1262176-1262883 (Clockwise)

Preceding gene: 238026791

Following gene: 238026793

Centisome position: 32.31

GC content: 65.11

Gene sequence:

>708_bases
GTGCCGATGCCCAGCAACATTCTCGTCATCGAAGATGAGCCCGCGATTTCCGAACTGATTTCGGTCAACCTTCAGCATGC
GGGACATTGTGCGATTCGCGCGTACAACGCGGAGCAGGCCCAGAACCTGATCAGCGACGTGCTACCTGATCTCGTCCTGC
TCGACTGGATGCTGCCGGGCAAGTCGGGGATCGCGTTCGCGCGCGAACTGCGCAACAACGAGCGCACCAAGCACATCCCC
ATCATCATGCTGACGGCGCGCGGCGACGAGCAGGACAAGGTGCTGGGCCTCGAGATCGGCGCGGACGATTACGTGACCAA
GCCCTTCTCGCCGAAGGAGCTGATGGCGCGCATCAAGGCGGTGCTGCGCCGCCGCGCGCCGCAACTGACCGAGGACGTGG
TGTCGATCAACGGCCTGCGGCTGGACCCGGCCACGCATCGCGTGGCGGCCAGCGCCGAAGGCAGCGAGATCAAGCTCGAT
CTCGGCCCGACCGAGTTCCGCCTGCTGCACTTCTTCATGACGCATCCGGAGCGCGTCCACAGCCGCACGCAGCTGCTCGA
CCAGGTGTGGGGCGACCACGTGTTCGTCGAGGAGCGTACCGTAGATGTCCACATCAAGCGCCTGCGCGCGGCACTGAAGC
CCGCCGGCTGCGATGCTATGATCGAAACCGTGCGCGGCAGCGGCTACCGCCTCGCCAAGCATGCCTGA

Upstream 100 bases:

>100_bases
CATCTACATCGTGAAGGGCACCGACGTGCGGCACCAGCCGCGCGACCTGCTCGATCGCGAAGCCAATAGCTAACCCACGT
CAGAACAAGGACGGACAGAG

Downstream 100 bases:

>100_bases
CCTGGCACGGCGCGCGTGCCGCGCGCCGTCTCTCACCGTTCTCCCGTCTTCTTTCTCGCGCCAGCCATGAACATCATCTG
GGTGCGCTTCCTGGTGTCGC

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPMPSNILVIEDEPAISELISVNLQHAGHCAIRAYNAEQAQNLISDVLPDLVLLDWMLPGKSGIAFARELRNNERTKHIP
IIMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKAVLRRRAPQLTEDVVSINGLRLDPATHRVAASAEGSEIKLD
LGPTEFRLLHFFMTHPERVHSRTQLLDQVWGDHVFVEERTVDVHIKRLRAALKPAGCDAMIETVRGSGYRLAKHA

Sequences:

>Translated_235_residues
MPMPSNILVIEDEPAISELISVNLQHAGHCAIRAYNAEQAQNLISDVLPDLVLLDWMLPGKSGIAFARELRNNERTKHIP
IIMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKAVLRRRAPQLTEDVVSINGLRLDPATHRVAASAEGSEIKLD
LGPTEFRLLHFFMTHPERVHSRTQLLDQVWGDHVFVEERTVDVHIKRLRAALKPAGCDAMIETVRGSGYRLAKHA
>Mature_234_residues
PMPSNILVIEDEPAISELISVNLQHAGHCAIRAYNAEQAQNLISDVLPDLVLLDWMLPGKSGIAFARELRNNERTKHIPI
IMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKAVLRRRAPQLTEDVVSINGLRLDPATHRVAASAEGSEIKLDL
GPTEFRLLHFFMTHPERVHSRTQLLDQVWGDHVFVEERTVDVHIKRLRAALKPAGCDAMIETVRGSGYRLAKHA

Specific function: This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by phoB and phoR when phosphate is limited [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=57.3913043478261, Blast_Score=281, Evalue=3e-77,
Organism=Escherichia coli, GI1788394, Length=242, Percent_Identity=41.3223140495868, Blast_Score=162, Evalue=1e-41,
Organism=Escherichia coli, GI1789809, Length=232, Percent_Identity=37.9310344827586, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786784, Length=225, Percent_Identity=36, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1790860, Length=228, Percent_Identity=38.1578947368421, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=34.6153846153846, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787375, Length=223, Percent_Identity=33.6322869955157, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI2367329, Length=234, Percent_Identity=39.3162393162393, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=34.9775784753363, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1786911, Length=233, Percent_Identity=34.7639484978541, Blast_Score=121, Evalue=5e-29,
Organism=Escherichia coli, GI1787229, Length=237, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=34.3612334801762, Blast_Score=104, Evalue=4e-24,
Organism=Escherichia coli, GI1790552, Length=225, Percent_Identity=32.4444444444444, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=30.8641975308642, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.042735042735, Blast_Score=68, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR011879
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26285; Mature: 26154

Theoretical pI: Translated: 6.86; Mature: 6.86

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMPSNILVIEDEPAISELISVNLQHAGHCAIRAYNAEQAQNLISDVLPDLVLLDWMLPG
CCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCC
KSGIAFARELRNNERTKHIPIIMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKA
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
VLRRRAPQLTEDVVSINGLRLDPATHRVAASAEGSEIKLDLGPTEFRLLHFFMTHPERVH
HHHHCCCHHHHHHHHCCCEEECCHHHHEEECCCCCEEEEECCCHHHHHHHHHHCCHHHHH
SRTQLLDQVWGDHVFVEERTVDVHIKRLRAALKPAGCDAMIETVRGSGYRLAKHA
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCC
>Mature Secondary Structure 
PMPSNILVIEDEPAISELISVNLQHAGHCAIRAYNAEQAQNLISDVLPDLVLLDWMLPG
CCCCCEEEECCCHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHCCC
KSGIAFARELRNNERTKHIPIIMLTARGDEQDKVLGLEIGADDYVTKPFSPKELMARIKA
CCCHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHH
VLRRRAPQLTEDVVSINGLRLDPATHRVAASAEGSEIKLDLGPTEFRLLHFFMTHPERVH
HHHHCCCHHHHHHHHCCCEEECCHHHHEEECCCCCEEEEECCCHHHHHHHHHHCCHHHHH
SRTQLLDQVWGDHVFVEERTVDVHIKRLRAALKPAGCDAMIETVRGSGYRLAKHA
HHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCCHHHHHHHHCCCCEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]