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The map label for this gene is degP [H]

Identifier: 238026613

GI number: 238026613

Start: 1034871

End: 1036409

Strand: Direct

Name: degP [H]

Synonym: bglu_1g09600

Alternate gene names: 238026613

Gene position: 1034871-1036409 (Clockwise)

Preceding gene: 238026612

Following gene: 238026614

Centisome position: 26.49

GC content: 69.92

Gene sequence:

>1539_bases
ATGATCACATTCACGCTGCGTCCCTGGATGGCCGCAGCGGCGCTGACGGCTTGCCTGCCCGTCGCGTCGCTGGCGGCGCA
AACCGCCGCGCCCGTGCAGGGCGCGTCCGCACCGGTCACCGTGCCGGTCGCGCCGCCCACCGCGCCGGCGGCGCGCGCGG
CGCTGCCCGATTTCGCGGATCTGGTCGAAAAGGTGGGCCCGGCGGTCGTCAACATCCGCACCACCGCGATCGTGCCGGCC
GATCCGCGCGGCGGCGTGTTCCCGCAGGGGCCGGACGACGGTGACATGTCGGAGTTCTTCCGCCGCTTTTTCGGCATTCC
GCTGCCGGGCGCGCCGGGTTCGCCCGGCACGCCGAAGAACGCCTTGCCCGACGCGCCCGACACCGAGCAGAACCGCGGCG
TGGGCTCGGGCTTCATCCTGTCGCCGGACGGTTATGTGATGACGAACGCGCACGTGGTCGACGACGCCGACACCATCTAC
GTTACGCTGACCGACAAGCGCGAGTTCAAGGCCAAGCTGATCGGCGTGGACGAGCGCACCGACGTGGCGATCGTCAAGAT
CAACGCCAGCGGCCTGCCGACCGTGGCGATCGGCGATTCGAACAAGGTGCGCGTGGGCGAGTGGGTGGTCGCGATCGGTT
CGCCGTTCGGGCTCGACAATACGGTCACGGCCGGCATCGTCAGCGCGAAGGGCCGCAACACGGGCGACTACCTGCCCTTC
ATCCAGACCGACGTGGCGGTCAACCCGGGCAACTCGGGCGGCCCGCTGATCAACATGCAGGGCGAGGTGATCGGCATCAA
CTCGCAGATCTACAGCCGCACTGGCGGCTTCATGGGGATCTCGTTCGCGATTCCGATCGATGAGGCGATGCGCGTGGCCG
AGCAACTGAAGACCACGGGCAAGGTCACGCGCGGGCGCATCGCGGTGGCGATCGCCGAGGTCACCAAGGACGTGGCCGAC
TCGATCGGGCTGCCGCGCGCGGAAGGCGCCCTGGTCAGCAGCGTCGTGGCGGGCGGCCCGGCCGACAAGGCCGGCGTGCA
GCCCGGCGACATCATCCTCAAGTTCAACGGCCGCCAGGTGGATGAAGCCACCGACCTGCCGCGCATGGTCGGCGACACCA
AGCCGGGCACCCAGGCGACGCTGACGATCTGGCGCAAGGGCAGCTCGCGCGACTTGCCGATCACGATCGCCGAGGTGCCG
GCCGAGAAGAACGCGCGCGCCGACGACGGCAAGCCGCGCCGGCCCGCCACGCCGCGCCAGAGCAACGCGCTCGGGCTGAC
GGTCAGCGACCTGACGGCGGACCAGTTGAAGGCCGCGAAGGTGCCGAACGGCGTGCACGTCGACCTGGCCGAAGGGCCGG
CCTCGCGCGCGGGCCTGAAGCGCGACGACATCGTGATCCGCGTCGGCGACGTCGATATCACGAGCGCGAAGCAGTTCGTC
GAGGTCACCTCTAAGCTCGATCCGCAGAAGATGGTCGCGGTGCTGGTGCGACGCGGCGACAACACGCAGTTCGTCCCGCT
GCGGCCGCGGCAGAAGTAG

Upstream 100 bases:

>100_bases
TCTGGATCACGCTGCTCGGCGAAGTGCCGCCGGCGACGTTGCAGCAGTTCGCGGCTGCCATAGAATACAAGCCTTCGAAG
TAATCTTCCGGTTTCCCGAC

Downstream 100 bases:

>100_bases
GTCGCGCATGGCGCTGACGCTGTACGGCCGCGGCTGGTGCCACCTGTGCGGCGAGATGCGTGCCGCACTGGCGCCGCTCG
CGGCCGAATTCGGCGTGGAG

Product: Do family proteasen

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MITFTLRPWMAAAALTACLPVASLAAQTAAPVQGASAPVTVPVAPPTAPAARAALPDFADLVEKVGPAVVNIRTTAIVPA
DPRGGVFPQGPDDGDMSEFFRRFFGIPLPGAPGSPGTPKNALPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIY
VTLTDKREFKAKLIGVDERTDVAIVKINASGLPTVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPF
IQTDVAVNPGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKTTGKVTRGRIAVAIAEVTKDVAD
SIGLPRAEGALVSSVVAGGPADKAGVQPGDIILKFNGRQVDEATDLPRMVGDTKPGTQATLTIWRKGSSRDLPITIAEVP
AEKNARADDGKPRRPATPRQSNALGLTVSDLTADQLKAAKVPNGVHVDLAEGPASRAGLKRDDIVIRVGDVDITSAKQFV
EVTSKLDPQKMVAVLVRRGDNTQFVPLRPRQK

Sequences:

>Translated_512_residues
MITFTLRPWMAAAALTACLPVASLAAQTAAPVQGASAPVTVPVAPPTAPAARAALPDFADLVEKVGPAVVNIRTTAIVPA
DPRGGVFPQGPDDGDMSEFFRRFFGIPLPGAPGSPGTPKNALPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIY
VTLTDKREFKAKLIGVDERTDVAIVKINASGLPTVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPF
IQTDVAVNPGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKTTGKVTRGRIAVAIAEVTKDVAD
SIGLPRAEGALVSSVVAGGPADKAGVQPGDIILKFNGRQVDEATDLPRMVGDTKPGTQATLTIWRKGSSRDLPITIAEVP
AEKNARADDGKPRRPATPRQSNALGLTVSDLTADQLKAAKVPNGVHVDLAEGPASRAGLKRDDIVIRVGDVDITSAKQFV
EVTSKLDPQKMVAVLVRRGDNTQFVPLRPRQK
>Mature_512_residues
MITFTLRPWMAAAALTACLPVASLAAQTAAPVQGASAPVTVPVAPPTAPAARAALPDFADLVEKVGPAVVNIRTTAIVPA
DPRGGVFPQGPDDGDMSEFFRRFFGIPLPGAPGSPGTPKNALPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIY
VTLTDKREFKAKLIGVDERTDVAIVKINASGLPTVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPF
IQTDVAVNPGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKTTGKVTRGRIAVAIAEVTKDVAD
SIGLPRAEGALVSSVVAGGPADKAGVQPGDIILKFNGRQVDEATDLPRMVGDTKPGTQATLTIWRKGSSRDLPITIAEVP
AEKNARADDGKPRRPATPRQSNALGLTVSDLTADQLKAAKVPNGVHVDLAEGPASRAGLKRDDIVIRVGDVDITSAKQFV
EVTSKLDPQKMVAVLVRRGDNTQFVPLRPRQK

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=363, Percent_Identity=33.6088154269972, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI22129776, Length=406, Percent_Identity=32.0197044334975, Blast_Score=155, Evalue=9e-38,
Organism=Homo sapiens, GI24308541, Length=250, Percent_Identity=35.6, Blast_Score=152, Evalue=8e-37,
Organism=Homo sapiens, GI7019477, Length=251, Percent_Identity=39.0438247011952, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1789629, Length=480, Percent_Identity=36.25, Blast_Score=257, Evalue=1e-69,
Organism=Escherichia coli, GI1786356, Length=490, Percent_Identity=32.8571428571429, Blast_Score=232, Evalue=5e-62,
Organism=Escherichia coli, GI1789630, Length=277, Percent_Identity=38.6281588447653, Blast_Score=183, Evalue=3e-47,
Organism=Drosophila melanogaster, GI24646839, Length=262, Percent_Identity=37.4045801526718, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 53440; Mature: 53440

Theoretical pI: Translated: 7.52; Mature: 7.52

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITFTLRPWMAAAALTACLPVASLAAQTAAPVQGASAPVTVPVAPPTAPAARAALPDFAD
CEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHCCCHHHH
LVEKVGPAVVNIRTTAIVPADPRGGVFPQGPDDGDMSEFFRRFFGIPLPGAPGSPGTPKN
HHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
ALPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERT
CCCCCCCCCCCCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCC
DVAIVKINASGLPTVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPF
CEEEEEEECCCCCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCE
IQTDVAVNPGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKTTG
EEECEEECCCCCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHC
KVTRGRIAVAIAEVTKDVADSIGLPRAEGALVSSVVAGGPADKAGVQPGDIILKFNGRQV
CCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
DEATDLPRMVGDTKPGTQATLTIWRKGSSRDLPITIAEVPAEKNARADDGKPRRPATPRQ
CHHHCCHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
SNALGLTVSDLTADQLKAAKVPNGVHVDLAEGPASRAGLKRDDIVIRVGDVDITSAKQFV
CCEEEEEECCCCHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCHHHHHHH
EVTSKLDPQKMVAVLVRRGDNTQFVPLRPRQK
HHHHCCCHHHHHHHHHCCCCCCEEEECCCCCC
>Mature Secondary Structure
MITFTLRPWMAAAALTACLPVASLAAQTAAPVQGASAPVTVPVAPPTAPAARAALPDFAD
CEEEEECHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHCCCHHHH
LVEKVGPAVVNIRTTAIVPADPRGGVFPQGPDDGDMSEFFRRFFGIPLPGAPGSPGTPKN
HHHHCCCEEEEEEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCC
ALPDAPDTEQNRGVGSGFILSPDGYVMTNAHVVDDADTIYVTLTDKREFKAKLIGVDERT
CCCCCCCCCCCCCCCCCEEECCCCEEEECCEEECCCCEEEEEEECCCCEEEEEECCCCCC
DVAIVKINASGLPTVAIGDSNKVRVGEWVVAIGSPFGLDNTVTAGIVSAKGRNTGDYLPF
CEEEEEEECCCCCEEEECCCCCEEECEEEEEECCCCCCCCCEEEEEEECCCCCCCCCCCE
IQTDVAVNPGNSGGPLINMQGEVIGINSQIYSRTGGFMGISFAIPIDEAMRVAEQLKTTG
EEECEEECCCCCCCCEEEECCCEEEECHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHC
KVTRGRIAVAIAEVTKDVADSIGLPRAEGALVSSVVAGGPADKAGVQPGDIILKFNGRQV
CCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCCCCCCCCCEEEEECCCCC
DEATDLPRMVGDTKPGTQATLTIWRKGSSRDLPITIAEVPAEKNARADDGKPRRPATPRQ
CHHHCCHHHHCCCCCCCCEEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCC
SNALGLTVSDLTADQLKAAKVPNGVHVDLAEGPASRAGLKRDDIVIRVGDVDITSAKQFV
CCEEEEEECCCCHHHHHHHCCCCCCEEEECCCCCHHCCCCCCCEEEEECCCCCHHHHHHH
EVTSKLDPQKMVAVLVRRGDNTQFVPLRPRQK
HHHHCCCHHHHHHHHHCCCCCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7861951 [H]