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The map label for this gene is fabF [H]

Identifier: 238026608

GI number: 238026608

Start: 1030683

End: 1031921

Strand: Direct

Name: fabF [H]

Synonym: bglu_1g09550

Alternate gene names: 238026608

Gene position: 1030683-1031921 (Clockwise)

Preceding gene: 238026607

Following gene: 339905960

Centisome position: 26.38

GC content: 65.29

Gene sequence:

>1239_bases
GTGAGCCGCCGCCGAGTTGTCGTTACAGGCCTGGGGCTGATTTCGCCTGTTGGCAATAATGTTGCCGACGGTTGGGCCAA
TCTCGTTGCCGGAAAATCCGGCATCGTCAATATCACCAAGTTCGATGCCACGAATTTTTCGACCCGCTTTGCGGGCGAGG
TGAAGGACTTCGACGTCGAAGCGTACCTGCCGGCGAAGGAAGCACGCCACATGGATACCTTCATCCATTACGGCATCGCA
GCGGGCATGCAGGCCATGAAGGACTGCGGTCTCGAAGTGACCGACGAGAATTCGGAGCGCATCGGCGTCGTGGTGGGCTC
CGGCATCGGCGGGCTGCCGATGATCGAGGTCACGCAGACCGAACTGCTCAATCGCGGCCCGCGCCGCATCTCGCCGTTCT
TCGTGCCGGCCTCGATCATCAATATGATCTCGGGCCACCTGTCGATCAAGTTTGGCCTGAAAGGCCCGAACCTCGCGATC
GTGACGGCCTGTACCACGGGCCTGCACTGCATCGGTGAGGCGGCCCGCCTGATCGAGTACGGCGACGCCGACGTGATGAT
CGCGGGCGGCGCGGAAGCGACCGTCTCGCCGCTCGGCATCGGCGGCTTCGCGGCCGCGCGCGCGCTGTCGCAGCGCAACG
ACGACCCGGCCACGGCGAGCCGTCCGTGGGACAAGGACCGCGACGGCTTCGTGCTCGGCGAGGGGGCCGGCGTGATGGTG
CTCGAGGAGTACGAGCATGCGAAGGCGCGCGGCGCGAAGATCTACGCCGAAGTGGCGGGCTACGGCATGAGCGCCGATGC
CCATCACATGACCGCCCCGGTCGAGGACGGCGACGGCGCGCGCCGCTGCATGCTGGCCGCGCTGCGCAACGCCGGCGTCA
ATCCCGACGAGGTCAACTACCTGAACGCGCACGGCACCTCGACGCCGCTCGGCGACCTGGCCGAGACGACCGGCATCAAG
CGGGCGTTCGGCGATCGCGCCAAGCAGATGGTGGTCAACTCGACGAAGTCGATGACGGGCCACCTGCTGGGCGGCGCGGG
CGGCCTCGAATCGGTGTTTACGGTGCTCGCCGTGCACAACCAGGTGTCGCCGCCGACCATCAACATCTTCAATCAGGATC
CCGAATGTGATCTCGATTACTGCGCGAACCAGGCGCGGGACATGAAGATCGACGTCGCGCTGAAGAACTCCTTCGGCTTT
GGCGGGACTAACGGCACGCTGGTTTTCAAGCGCGTCTGA

Upstream 100 bases:

>100_bases
GCATCGATGCCGGCCGCGTTAACAGCCACAGGGCTCGCAGGGCTGGTTCCTGCGGCCGCTGTGGCTTTTGCTTTAGTCAT
TCAATGGAAAAGAGGGTACC

Downstream 100 bases:

>100_bases
AGCGGGGTCGCTTGACGGATCCCTTCCTCCTGTTTTCCGCCGGCACGCAGCCCGTTGCGCTGCGTGCCTCGGCGACGCTG
CGCGTCGCGTTGGCGGCGTT

Product: 3-oxoacyl-(acyl carrier protein) synthase II

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKDFDVEAYLPAKEARHMDTFIHYGIA
AGMQAMKDCGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISGHLSIKFGLKGPNLAI
VTACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVLGEGAGVMV
LEEYEHAKARGAKIYAEVAGYGMSADAHHMTAPVEDGDGARRCMLAALRNAGVNPDEVNYLNAHGTSTPLGDLAETTGIK
RAFGDRAKQMVVNSTKSMTGHLLGGAGGLESVFTVLAVHNQVSPPTINIFNQDPECDLDYCANQARDMKIDVALKNSFGF
GGTNGTLVFKRV

Sequences:

>Translated_412_residues
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKDFDVEAYLPAKEARHMDTFIHYGIA
AGMQAMKDCGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISGHLSIKFGLKGPNLAI
VTACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVLGEGAGVMV
LEEYEHAKARGAKIYAEVAGYGMSADAHHMTAPVEDGDGARRCMLAALRNAGVNPDEVNYLNAHGTSTPLGDLAETTGIK
RAFGDRAKQMVVNSTKSMTGHLLGGAGGLESVFTVLAVHNQVSPPTINIFNQDPECDLDYCANQARDMKIDVALKNSFGF
GGTNGTLVFKRV
>Mature_411_residues
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKDFDVEAYLPAKEARHMDTFIHYGIAA
GMQAMKDCGLEVTDENSERIGVVVGSGIGGLPMIEVTQTELLNRGPRRISPFFVPASIINMISGHLSIKFGLKGPNLAIV
TACTTGLHCIGEAARLIEYGDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVLGEGAGVMVL
EEYEHAKARGAKIYAEVAGYGMSADAHHMTAPVEDGDGARRCMLAALRNAGVNPDEVNYLNAHGTSTPLGDLAETTGIKR
AFGDRAKQMVVNSTKSMTGHLLGGAGGLESVFTVLAVHNQVSPPTINIFNQDPECDLDYCANQARDMKIDVALKNSFGFG
GTNGTLVFKRV

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Has a preference for short chain acid substrates and may function to supply the octanoic substrates for lipoic acid biosynthes

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=416, Percent_Identity=47.3557692307692, Blast_Score=381, Evalue=1e-106,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=54.4827586206897, Blast_Score=162, Evalue=7e-40,
Organism=Homo sapiens, GI41872631, Length=429, Percent_Identity=25.8741258741259, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1787337, Length=413, Percent_Identity=61.0169491525424, Blast_Score=504, Evalue=1e-144,
Organism=Escherichia coli, GI1788663, Length=414, Percent_Identity=38.8888888888889, Blast_Score=267, Evalue=8e-73,
Organism=Caenorhabditis elegans, GI71983541, Length=418, Percent_Identity=36.6028708133971, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71983535, Length=260, Percent_Identity=41.1538461538462, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI212642053, Length=355, Percent_Identity=25.9154929577465, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550940, Length=412, Percent_Identity=23.5436893203883, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320904, Length=446, Percent_Identity=36.5470852017937, Blast_Score=278, Evalue=8e-76,
Organism=Drosophila melanogaster, GI24644341, Length=418, Percent_Identity=45.6937799043062, Blast_Score=357, Evalue=6e-99,
Organism=Drosophila melanogaster, GI221330659, Length=378, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19920632, Length=378, Percent_Identity=26.1904761904762, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24581345, Length=427, Percent_Identity=23.6533957845433, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 43488; Mature: 43357

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKDFDVE
CCCCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEECCCCCCCCEE
AYLPAKEARHMDTFIHYGIAAGMQAMKDCGLEVTDENSERIGVVVGSGIGGLPMIEVTQT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCEEEEHHH
ELLNRGPRRISPFFVPASIINMISGHLSIKFGLKGPNLAIVTACTTGLHCIGEAARLIEY
HHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHCC
GDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEVAGYGMSADAHHMTAPVEDGDGARRCMLAALRNAGVNPDEVNY
EECCHHHHHCCCEEEEEHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LNAHGTSTPLGDLAETTGIKRAFGDRAKQMVVNSTKSMTGHLLGGAGGLESVFTVLAVHN
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCCCHHHHHHHHHHHC
QVSPPTINIFNQDPECDLDYCANQARDMKIDVALKNSFGFGGTNGTLVFKRV
CCCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC
>Mature Secondary Structure 
SRRRVVVTGLGLISPVGNNVADGWANLVAGKSGIVNITKFDATNFSTRFAGEVKDFDVE
CCCEEEEEECCHHCCCCCCHHHHHHHHHCCCCCEEEEEEECCCCCCCEECCCCCCCCEE
AYLPAKEARHMDTFIHYGIAAGMQAMKDCGLEVTDENSERIGVVVGSGIGGLPMIEVTQT
EECCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCEEEEEEECCCCCCCEEEEHHH
ELLNRGPRRISPFFVPASIINMISGHLSIKFGLKGPNLAIVTACTTGLHCIGEAARLIEY
HHHCCCCCCCCCEEEHHHHHHHHCCCEEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHCC
GDADVMIAGGAEATVSPLGIGGFAAARALSQRNDDPATASRPWDKDRDGFVLGEGAGVMV
CCCCEEEECCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEECCCCEEE
LEEYEHAKARGAKIYAEVAGYGMSADAHHMTAPVEDGDGARRCMLAALRNAGVNPDEVNY
EECCHHHHHCCCEEEEEHHCCCCCCCCCCEECCCCCCCHHHHHHHHHHHHCCCCCCCCEE
LNAHGTSTPLGDLAETTGIKRAFGDRAKQMVVNSTKSMTGHLLGGAGGLESVFTVLAVHN
EECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHCEEEECCCCCHHHHHHHHHHHC
QVSPPTINIFNQDPECDLDYCANQARDMKIDVALKNSFGFGGTNGTLVFKRV
CCCCCEEEEECCCCCCCHHHHCCCCCCEEEEEEEECCCCCCCCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550484 [H]