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The map label for this gene is nhaA [H]

Identifier: 238026598

GI number: 238026598

Start: 1022491

End: 1023483

Strand: Direct

Name: nhaA [H]

Synonym: bglu_1g09440

Alternate gene names: 238026598

Gene position: 1022491-1023483 (Clockwise)

Preceding gene: 238026597

Following gene: 238026601

Centisome position: 26.17

GC content: 67.47

Gene sequence:

>993_bases
ATGACCGACCAACCGATTTCTCCCGATTCCTCCGGCACCGCGCGCGGCGCCGGCCATGAACCCGGCTGGGAGCGCGCGGC
GCTCGAGCGCATCGCGATGGCGGCGATCATCGAGCAGCGCCGGGCGCGCCGCTGGCGCATCGCGTTCCGTTTCCTCTGGC
TGATCGCGGTGGTGGCGATCATGCTCGCGGTGTTCGACTTCTCGGGCGACGGCAAGCTGTCGAGCAGCCGCCACACCGCG
CTCGTGTCGATCGACGGCGAGATCGCGGCAGGCAACAGCGCCAACGCCGACGACATCAATTCCGCGCTCGACGACGCATT
CGACGATTCCGGCACGGTCGGCGTCGTGCTGCACATCAACAGCCCGGGCGGCAGCCCGGTGCAGGCCGGCATCGTCTACG
ACGAGATCCGCCGGCTGCGCAAGAAATACCCGTCGAAGCCGCTCTACGTGGTGGTCAGCGACATGTGCGCCTCGGGTGGC
TATTACATTGCCGCGGCGGCAGACCGGATCTACGTCAACAAGGCCAGCATCGTCGGCTCGATCGGCGTGCTGATGGACGG
CTTCGGCTTCACCGGCCTGATGGACAAGCTCGGCGTCGAGCGCCGGCTGCATACCTCGGGGGAGAACAAGGGCTTTTACG
ATCCGTTCTCGCCGGAAACACCGAAAATGGACGAGCATGCGCAGTCGATGCTCGACGAGATCCACGCGCAGTTCATCCAG
GCCGTGAAGGACGGCCGCGGCAAGCGGCTGCACGATTCGCCCGACATTTTCTCGGGGCTGTTCTGGACCGGCGCGAAGAG
CGTCGAACTCGGCCTCGCGGACGGCTTCGGCACCACCGACTCGGTCGCGCGCGACGTGCTGAAGGCGCCCGACATCGTCG
ACTACACGGTCAAGGAAAGCCTGAGCAGCCGCGTGGCGCGGCGCTTCGGCGCGGCGATCGGCGGCGGGGCGGTGAAATCG
GCGCTGTCGGACAGCGCGGTCCGGCTGCGCTGA

Upstream 100 bases:

>100_bases
CGAGGGCCGCGCCGTCTACTGGCTGCCCGACGGCGAACTGCGGCCGTCGGCGTCCTGACGCGTCGCCGATTTTTCTTTTC
CGACCCTCACTGGCCCACGC

Downstream 100 bases:

>100_bases
CGGCCGGCGGTCAAGCAGGCGGGCCCCGGCGGGCGAGGCGGCAAGGGCTGCCGCCCGGGCCGCTCAGTTCGCGAGCAGCA
GGAAGATCGCCGGCCGCTTC

Product: peptidase, U7 family protein

Products: NA

Alternate protein names: Sodium/proton antiporter nhaA [H]

Number of amino acids: Translated: 330; Mature: 329

Protein sequence:

>330_residues
MTDQPISPDSSGTARGAGHEPGWERAALERIAMAAIIEQRRARRWRIAFRFLWLIAVVAIMLAVFDFSGDGKLSSSRHTA
LVSIDGEIAAGNSANADDINSALDDAFDDSGTVGVVLHINSPGGSPVQAGIVYDEIRRLRKKYPSKPLYVVVSDMCASGG
YYIAAAADRIYVNKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFYDPFSPETPKMDEHAQSMLDEIHAQFIQ
AVKDGRGKRLHDSPDIFSGLFWTGAKSVELGLADGFGTTDSVARDVLKAPDIVDYTVKESLSSRVARRFGAAIGGGAVKS
ALSDSAVRLR

Sequences:

>Translated_330_residues
MTDQPISPDSSGTARGAGHEPGWERAALERIAMAAIIEQRRARRWRIAFRFLWLIAVVAIMLAVFDFSGDGKLSSSRHTA
LVSIDGEIAAGNSANADDINSALDDAFDDSGTVGVVLHINSPGGSPVQAGIVYDEIRRLRKKYPSKPLYVVVSDMCASGG
YYIAAAADRIYVNKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFYDPFSPETPKMDEHAQSMLDEIHAQFIQ
AVKDGRGKRLHDSPDIFSGLFWTGAKSVELGLADGFGTTDSVARDVLKAPDIVDYTVKESLSSRVARRFGAAIGGGAVKS
ALSDSAVRLR
>Mature_329_residues
TDQPISPDSSGTARGAGHEPGWERAALERIAMAAIIEQRRARRWRIAFRFLWLIAVVAIMLAVFDFSGDGKLSSSRHTAL
VSIDGEIAAGNSANADDINSALDDAFDDSGTVGVVLHINSPGGSPVQAGIVYDEIRRLRKKYPSKPLYVVVSDMCASGGY
YIAAAADRIYVNKASIVGSIGVLMDGFGFTGLMDKLGVERRLHTSGENKGFYDPFSPETPKMDEHAQSMLDEIHAQFIQA
VKDGRGKRLHDSPDIFSGLFWTGAKSVELGLADGFGTTDSVARDVLKAPDIVDYTVKESLSSRVARRFGAAIGGGAVKSA
LSDSAVRLR

Specific function: Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons [H]

COG id: COG0616

COG function: function code OU; Periplasmic serine proteases (ClpP class)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase S49 family [H]

Homologues:

Organism=Escherichia coli, GI1787527, Length=235, Percent_Identity=31.4893617021277, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788064, Length=207, Percent_Identity=30.4347826086957, Blast_Score=68, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023171
- InterPro:   IPR004670
- InterPro:   IPR002142 [H]

Pfam domain/function: PF06965 Na_H_antiport_1; PF01343 Peptidase_S49 [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 35398; Mature: 35267

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQPISPDSSGTARGAGHEPGWERAALERIAMAAIIEQRRARRWRIAFRFLWLIAVVAI
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAVFDFSGDGKLSSSRHTALVSIDGEIAAGNSANADDINSALDDAFDDSGTVGVVLHIN
HHHHHCCCCCCCCCCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
SPGGSPVQAGIVYDEIRRLRKKYPSKPLYVVVSDMCASGGYYIAAAADRIYVNKASIVGS
CCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCEEEEEECCEEEEEHHHHHHH
IGVLMDGFGFTGLMDKLGVERRLHTSGENKGFYDPFSPETPKMDEHAQSMLDEIHAQFIQ
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKDGRGKRLHDSPDIFSGLFWTGAKSVELGLADGFGTTDSVARDVLKAPDIVDYTVKES
HHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LSSRVARRFGAAIGGGAVKSALSDSAVRLR
HHHHHHHHHHHHHCCHHHHHHHCCCCEECC
>Mature Secondary Structure 
TDQPISPDSSGTARGAGHEPGWERAALERIAMAAIIEQRRARRWRIAFRFLWLIAVVAI
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MLAVFDFSGDGKLSSSRHTALVSIDGEIAAGNSANADDINSALDDAFDDSGTVGVVLHIN
HHHHHCCCCCCCCCCCCCEEEEEECCEEECCCCCCHHHHHHHHHHHCCCCCCEEEEEEEE
SPGGSPVQAGIVYDEIRRLRKKYPSKPLYVVVSDMCASGGYYIAAAADRIYVNKASIVGS
CCCCCCEEHHHHHHHHHHHHHHCCCCCEEEEEEHHHCCCCEEEEEECCEEEEEHHHHHHH
IGVLMDGFGFTGLMDKLGVERRLHTSGENKGFYDPFSPETPKMDEHAQSMLDEIHAQFIQ
HHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
AVKDGRGKRLHDSPDIFSGLFWTGAKSVELGLADGFGTTDSVARDVLKAPDIVDYTVKES
HHHCCCCCCCCCCCHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCHHHHHHHHH
LSSRVARRFGAAIGGGAVKSALSDSAVRLR
HHHHHHHHHHHHHCCHHHHHHHCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA