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The map label for this gene is exuR [H]

Identifier: 238025175

GI number: 238025175

Start: 2301786

End: 2302496

Strand: Reverse

Name: exuR [H]

Synonym: bglu_2g18460

Alternate gene names: 238025175

Gene position: 2302496-2301786 (Counterclockwise)

Preceding gene: 238025185

Following gene: 238025173

Centisome position: 81.44

GC content: 71.17

Gene sequence:

>711_bases
ATGAAAGCAACCGAGCCCAAGCGGCTTTACCAATCGATTGCCGCCCAGATCCTGACGCTGATTCGCCGCGGCGATTTCCC
GCCCGGCGAGCGGCTGCCGCCGGAACGCGAGCTGGCGATGAAGCTCGGCGTGTCGCGTCCGTCGCTGCGCGAGGCGCTGA
TCGCGCTCGAAATCGGCGGCAACGTGGAGATCCGGGTCGGTTCGGGGGTCTATGTGCGCGAGGCGGGCGTCGGCGACGAA
GCCGCCGTCGCGTCACTGGGCGACAGCCCGTCGGAGCTGATGCAGGCGCGCGCGGCCATCGAGGGCAGCGTCACGGTGCT
GGCCGCGGCGCGCATGACGGCGGCGATGGCCGATCGCCTGCGCCGCTCGATCGAGCGGATGCATCGGCTGGCCGCGGCCG
GCAAGTCGCCGGTCGAGGCGGACCGGCAGTTCCACATGCTGATCGCGGAGGCCGCGGGCAATTCGGTGCTGAGCCGCTTC
GTCGCCGAACTGTTCGACAGCCGCCATGATCCGATCGCGGCCGCGCTGCGGGGGCATGTGGAGAACCCGGTCACCTGGAC
CGCCGCGGCGCGCGAGCACGAGGACATCCTGCGGGCACTGCAGTCGGGCGATCCGATCGCCGCGCAAACGGCGATGCGCA
CCCATCTGCGGGCCTCCGAAGGACGGTGGACGGACGGCGAGATGGCCGCGCAGAGCCGCACGGCCGATTAG

Upstream 100 bases:

>100_bases
CTGATGCGCGGCGGCAGGTCCGTCGATCGCGGCTTGCAGGGCATGCTAGACTTGCCCGGCCCCACGCCCCGCGTGGTATT
CCGCTCGCCGAACCCTCACC

Downstream 100 bases:

>100_bases
CAGGCCGCGGCGTAGCGGCGGCTGAGGCGGGGCGGGCGCGGCGGCGGCGGCCGAGGCGGGCGTGCCGCCGCCGCGGAACT
AGGCGACGGAATCGGCCAGT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKATEPKRLYQSIAAQILTLIRRGDFPPGERLPPERELAMKLGVSRPSLREALIALEIGGNVEIRVGSGVYVREAGVGDE
AAVASLGDSPSELMQARAAIEGSVTVLAAARMTAAMADRLRRSIERMHRLAAAGKSPVEADRQFHMLIAEAAGNSVLSRF
VAELFDSRHDPIAAALRGHVENPVTWTAAAREHEDILRALQSGDPIAAQTAMRTHLRASEGRWTDGEMAAQSRTAD

Sequences:

>Translated_236_residues
MKATEPKRLYQSIAAQILTLIRRGDFPPGERLPPERELAMKLGVSRPSLREALIALEIGGNVEIRVGSGVYVREAGVGDE
AAVASLGDSPSELMQARAAIEGSVTVLAAARMTAAMADRLRRSIERMHRLAAAGKSPVEADRQFHMLIAEAAGNSVLSRF
VAELFDSRHDPIAAALRGHVENPVTWTAAAREHEDILRALQSGDPIAAQTAMRTHLRASEGRWTDGEMAAQSRTAD
>Mature_236_residues
MKATEPKRLYQSIAAQILTLIRRGDFPPGERLPPERELAMKLGVSRPSLREALIALEIGGNVEIRVGSGVYVREAGVGDE
AAVASLGDSPSELMQARAAIEGSVTVLAAARMTAAMADRLRRSIERMHRLAAAGKSPVEADRQFHMLIAEAAGNSVLSRF
VAELFDSRHDPIAAALRGHVENPVTWTAAAREHEDILRALQSGDPIAAQTAMRTHLRASEGRWTDGEMAAQSRTAD

Specific function: Repressor for the exu regulon that encode genes involved in hexuronate utilization. It regulates the exuT, uxaCA and uxuRAB operons. Binds D-tagaturonate and D-fructuronate as inducers [H]

COG id: COG2186

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790780, Length=227, Percent_Identity=37.0044052863436, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082208, Length=229, Percent_Identity=35.3711790393013, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1790032, Length=223, Percent_Identity=31.390134529148, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1786303, Length=163, Percent_Identity=36.8098159509202, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1789621, Length=229, Percent_Identity=29.2576419213974, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1789353, Length=236, Percent_Identity=30.0847457627119, Blast_Score=73, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011711
- InterPro:   IPR000524
- InterPro:   IPR011991 [H]

Pfam domain/function: PF07729 FCD; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 25449; Mature: 25449

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKATEPKRLYQSIAAQILTLIRRGDFPPGERLPPERELAMKLGVSRPSLREALIALEIGG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHEEECC
NVEIRVGSGVYVREAGVGDEAAVASLGDSPSELMQARAAIEGSVTVLAAARMTAAMADRL
EEEEEECCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RRSIERMHRLAAAGKSPVEADRQFHMLIAEAAGNSVLSRFVAELFDSRHDPIAAALRGHV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHCCC
ENPVTWTAAAREHEDILRALQSGDPIAAQTAMRTHLRASEGRWTDGEMAAQSRTAD
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC
>Mature Secondary Structure
MKATEPKRLYQSIAAQILTLIRRGDFPPGERLPPERELAMKLGVSRPSLREALIALEIGG
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHEEECC
NVEIRVGSGVYVREAGVGDEAAVASLGDSPSELMQARAAIEGSVTVLAAARMTAAMADRL
EEEEEECCCEEEEECCCCCHHHHHHCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RRSIERMHRLAAAGKSPVEADRQFHMLIAEAAGNSVLSRFVAELFDSRHDPIAAALRGHV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHHCCC
ENPVTWTAAAREHEDILRALQSGDPIAAQTAMRTHLRASEGRWTDGEMAAQSRTAD
CCCEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA