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The map label for this gene is rstA [H]

Identifier: 238025151

GI number: 238025151

Start: 2270658

End: 2271365

Strand: Reverse

Name: rstA [H]

Synonym: bglu_2g18160

Alternate gene names: 238025151

Gene position: 2271365-2270658 (Counterclockwise)

Preceding gene: 238025153

Following gene: 238025150

Centisome position: 80.34

GC content: 68.64

Gene sequence:

>708_bases
ATGCCTTTTCGGATTCTCCTCGTCGAGGACGACAGCCGTCTGTCCACCCTGATCACCACCTATCTGCGCAAGCACGACTA
CGAAGTCGATACCGTGCTGGACGGCCATGCGGCGGTGCCGGCGATCCTCGCGTCGCGGCCCGACCTCGTGATCCTCGACG
TGAACCTGCCGGGCAAGGACGGCTTCGAGGTCTGCCGCGAGGCGCGCAAGCACTACGACGGCGTGATCGTGATGGTCACC
GCGCGCGACGAGCCCTACGACGAACTGCTGGGGCTCGAGTTCGGCGCCGACGACTACGTGCGCAAGCCGGTCGAGCCGCG
CATCCTGCTGGCGCGCATCAAGGCCCAGCTGCGGCGCTCGCCGGCGCGCGCGGCCGAAGCGGGCGCCGAGCCCGAGGCCT
TCGCGTTCGGCAAGTTCTCGATCCATCGCGGCAACCGCTCGGTGCGGCTGCCGGACGGCTCGTCGCCGGATCTCACGTCG
GCGGAATTCGACCTGCTTTGGGCGCTCGTGTGCCGCGCGGGCGAGGTGGTGAGCCGCGACGACCTGATGCTGCAACTGCG
CGGCGTGGAGTTCGACGGGCTCGACCGCACCATCGACGGCCGCATCTCGAAGCTGCGCCGCAAGCTGCAGGACGACGCGA
GCCACCCGCGCCGCATCAAGACGGTCCGCAGCAAGGGCTACCAGTTCAGCACCCATGAGTGGGAATAG

Upstream 100 bases:

>100_bases
ATGATTCGGATTAGTCTCGAATCTTACCGATGGTTAGCGGTCGGTCCGCGGGCCGGCCGGTCGCTGTTTTTCGCACGCAA
CACACGCAACGGTCTCACCC

Downstream 100 bases:

>100_bases
GACGGACCCGGGCCGCCGCGGCGCGGCCTGCCCGCCGCCCTCGCGCCTGCCGGCGCTGCGCTACCTGCGCTGGCGCTGGC
TGCGCTTCCGGCGCTCGTGG

Product: response regulator receiver

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MPFRILLVEDDSRLSTLITTYLRKHDYEVDTVLDGHAAVPAILASRPDLVILDVNLPGKDGFEVCREARKHYDGVIVMVT
ARDEPYDELLGLEFGADDYVRKPVEPRILLARIKAQLRRSPARAAEAGAEPEAFAFGKFSIHRGNRSVRLPDGSSPDLTS
AEFDLLWALVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLQDDASHPRRIKTVRSKGYQFSTHEWE

Sequences:

>Translated_235_residues
MPFRILLVEDDSRLSTLITTYLRKHDYEVDTVLDGHAAVPAILASRPDLVILDVNLPGKDGFEVCREARKHYDGVIVMVT
ARDEPYDELLGLEFGADDYVRKPVEPRILLARIKAQLRRSPARAAEAGAEPEAFAFGKFSIHRGNRSVRLPDGSSPDLTS
AEFDLLWALVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLQDDASHPRRIKTVRSKGYQFSTHEWE
>Mature_234_residues
PFRILLVEDDSRLSTLITTYLRKHDYEVDTVLDGHAAVPAILASRPDLVILDVNLPGKDGFEVCREARKHYDGVIVMVTA
RDEPYDELLGLEFGADDYVRKPVEPRILLARIKAQLRRSPARAAEAGAEPEAFAFGKFSIHRGNRSVRLPDGSSPDLTSA
EFDLLWALVCRAGEVVSRDDLMLQLRGVEFDGLDRTIDGRISKLRRKLQDDASHPRRIKTVRSKGYQFSTHEWE

Specific function: Member of the two-component regulatory system rstB/rstA [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI145693140, Length=237, Percent_Identity=44.3037974683544, Blast_Score=189, Evalue=1e-49,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=43.2314410480349, Blast_Score=172, Evalue=1e-44,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=41.4847161572052, Blast_Score=142, Evalue=1e-35,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=35.2422907488987, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1790863, Length=228, Percent_Identity=32.8947368421053, Blast_Score=125, Evalue=3e-30,
Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=34.468085106383, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=35.3488372093023, Blast_Score=117, Evalue=8e-28,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=36.7256637168142, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1790860, Length=226, Percent_Identity=33.6283185840708, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1787375, Length=229, Percent_Identity=31.8777292576419, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1786784, Length=228, Percent_Identity=32.0175438596491, Blast_Score=99, Evalue=2e-22,
Organism=Escherichia coli, GI1790552, Length=232, Percent_Identity=32.7586206896552, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1789402, Length=229, Percent_Identity=33.1877729257642, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786911, Length=238, Percent_Identity=31.5126050420168, Blast_Score=92, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26570; Mature: 26438

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFRILLVEDDSRLSTLITTYLRKHDYEVDTVLDGHAAVPAILASRPDLVILDVNLPGKD
CCEEEEEEECCCHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHCCCCCEEEEEECCCCCC
GFEVCREARKHYDGVIVMVTARDEPYDELLGLEFGADDYVRKPVEPRILLARIKAQLRRS
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCC
PARAAEAGAEPEAFAFGKFSIHRGNRSVRLPDGSSPDLTSAEFDLLWALVCRAGEVVSRD
HHHHHHCCCCCCEEEECEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
DLMLQLRGVEFDGLDRTIDGRISKLRRKLQDDASHPRRIKTVRSKGYQFSTHEWE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PFRILLVEDDSRLSTLITTYLRKHDYEVDTVLDGHAAVPAILASRPDLVILDVNLPGKD
CEEEEEEECCCHHHHHHHHHHHHCCCCHHEEECCCHHHHHHHCCCCCEEEEEECCCCCC
GFEVCREARKHYDGVIVMVTARDEPYDELLGLEFGADDYVRKPVEPRILLARIKAQLRRS
HHHHHHHHHHHCCCEEEEEEECCCCHHHHHCCCCCCCHHHHCCCCHHHHHHHHHHHHHCC
PARAAEAGAEPEAFAFGKFSIHRGNRSVRLPDGSSPDLTSAEFDLLWALVCRAGEVVSRD
HHHHHHCCCCCCEEEECEEEEEECCCEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
DLMLQLRGVEFDGLDRTIDGRISKLRRKLQDDASHPRRIKTVRSKGYQFSTHEWE
CEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1495392 [H]