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The map label for this gene is rstB [H]

Identifier: 238025150

GI number: 238025150

Start: 2269517

End: 2270671

Strand: Reverse

Name: rstB [H]

Synonym: bglu_2g18150

Alternate gene names: 238025150

Gene position: 2270671-2269517 (Counterclockwise)

Preceding gene: 238025151

Following gene: 238025148

Centisome position: 80.31

GC content: 72.47

Gene sequence:

>1155_bases
ATGAGTGGGAATAGGACGGACCCGGGCCGCCGCGGCGCGGCCTGCCCGCCGCCCTCGCGCCTGCCGGCGCTGCGCTACCT
GCGCTGGCGCTGGCTGCGCTTCCGGCGCTCGTGGACCGACACGCGTGCCGACCGCATGCCGAGCTGGTCGCGGCTCTACC
TGCGCGCCTACCTGCATCTGATGAGCCTGGTGCTGACGGTGGTGGCGGTGCCGCTGCTGGCGCTGGCGGCCACGCTGTCG
CCGCGCACCGTGCTGGCGGGCTTCGAGGCGCTGCCGGGCGGCGCGCTCGGCGTCGCGCTGTTCGTGATCGTGGTGCCGGC
GCTCGCCACCTGGCGCTGGGCGCGCCCGACCTGGAGCGACCTCGTGATGGTGCGCGAGCGCGCCATCGATTTCAGCGGCG
GGCGCTTCCACACGCGCGCGCGCGAATCGCACAGCGTGATCCTCGGGCCGCTCGCGCGCACGCTCAACGCGCTGGCGATG
CGCATGGAGCGCCTGATCGAGGCGCAGCGCGACCTGACCAACGGCATCTCGCACGAGCTGCGCACGCCGCTGGCGCGCGT
GCGCTTCGCGCTCGAGGCGCTGCGCGACCCGGCCTCCGACGCGGAGCGCCACGCCGCGCTCGACAGCATCGCGCAGGACG
TGACGGAACTCGACGAGCTGATCGACATGAGCCTCACCTACGCGCGGCTCGAATACAGTTCGCTGCAATCGAACCAGGCG
CCCACCGGGCTGGCCACCTGGCTCGAAACCCAGGTTCACGACGTCGCCCAGCTCGACCCGACCAAGCGCATCGAGATGCG
CATCGGCGTGCCGCGCGAGCTGCGCGTGAACATGGATACGCGGCTGATGTCCTACGCGATCCGCAATCTGCTGCGCAATG
CCGGCAAGTACGCGCGCTCGCGCATCGTGATCGGCGCGGCCGCCGGCGCCGACGGCGGCATCACCGTGTTCGTCGAGGAT
GACGGCCCCGGCGTGCCCGACATCGAGCGCGAGCGGATCTTCGACGCGTTCGTGCGGCTGGACCGCCATACCGCGGGCTA
CGGGCTCGGCCTCGCGATCACGCGGCAGGTGCTGCGGGCGCACCACGGCAACATCGTCGTGACCGACGCGCGCGAGCTGT
CCGGCGCGCGTTTCGAGATCGGCTGGCCGGGCTGA

Upstream 100 bases:

>100_bases
GACGGCCGCATCTCGAAGCTGCGCCGCAAGCTGCAGGACGACGCGAGCCACCCGCGCCGCATCAAGACGGTCCGCAGCAA
GGGCTACCAGTTCAGCACCC

Downstream 100 bases:

>100_bases
GGCCCGCCGGCCGCCGCGCCGCCTCGGCCGGGTTGCGGCCCGCGCGCCGTCCGTGCCCGAGCGGCGCTCAATAGGTCCGG
CCGAGCTGGAAGTACAGGTT

Product: Signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSGNRTDPGRRGAACPPPSRLPALRYLRWRWLRFRRSWTDTRADRMPSWSRLYLRAYLHLMSLVLTVVAVPLLALAATLS
PRTVLAGFEALPGGALGVALFVIVVPALATWRWARPTWSDLVMVRERAIDFSGGRFHTRARESHSVILGPLARTLNALAM
RMERLIEAQRDLTNGISHELRTPLARVRFALEALRDPASDAERHAALDSIAQDVTELDELIDMSLTYARLEYSSLQSNQA
PTGLATWLETQVHDVAQLDPTKRIEMRIGVPRELRVNMDTRLMSYAIRNLLRNAGKYARSRIVIGAAAGADGGITVFVED
DGPGVPDIERERIFDAFVRLDRHTAGYGLGLAITRQVLRAHHGNIVVTDARELSGARFEIGWPG

Sequences:

>Translated_384_residues
MSGNRTDPGRRGAACPPPSRLPALRYLRWRWLRFRRSWTDTRADRMPSWSRLYLRAYLHLMSLVLTVVAVPLLALAATLS
PRTVLAGFEALPGGALGVALFVIVVPALATWRWARPTWSDLVMVRERAIDFSGGRFHTRARESHSVILGPLARTLNALAM
RMERLIEAQRDLTNGISHELRTPLARVRFALEALRDPASDAERHAALDSIAQDVTELDELIDMSLTYARLEYSSLQSNQA
PTGLATWLETQVHDVAQLDPTKRIEMRIGVPRELRVNMDTRLMSYAIRNLLRNAGKYARSRIVIGAAAGADGGITVFVED
DGPGVPDIERERIFDAFVRLDRHTAGYGLGLAITRQVLRAHHGNIVVTDARELSGARFEIGWPG
>Mature_383_residues
SGNRTDPGRRGAACPPPSRLPALRYLRWRWLRFRRSWTDTRADRMPSWSRLYLRAYLHLMSLVLTVVAVPLLALAATLSP
RTVLAGFEALPGGALGVALFVIVVPALATWRWARPTWSDLVMVRERAIDFSGGRFHTRARESHSVILGPLARTLNALAMR
MERLIEAQRDLTNGISHELRTPLARVRFALEALRDPASDAERHAALDSIAQDVTELDELIDMSLTYARLEYSSLQSNQAP
TGLATWLETQVHDVAQLDPTKRIEMRIGVPRELRVNMDTRLMSYAIRNLLRNAGKYARSRIVIGAAAGADGGITVFVEDD
GPGVPDIERERIFDAFVRLDRHTAGYGLGLAITRQVLRAHHGNIVVTDARELSGARFEIGWPG

Specific function: Member of the two-component regulatory system rstB/rstA. RstB functions as a membrane-associated protein kinase that phosphorylates rstA (Potential) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1787894, Length=294, Percent_Identity=35.7142857142857, Blast_Score=161, Evalue=7e-41,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=31.2236286919831, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788393, Length=241, Percent_Identity=29.8755186721992, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1790551, Length=231, Percent_Identity=29.4372294372294, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=268, Percent_Identity=27.6119402985075, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1788549, Length=258, Percent_Identity=27.1317829457364, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=221, Percent_Identity=33.4841628959276, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI1787374, Length=257, Percent_Identity=28.4046692607004, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=244, Percent_Identity=28.2786885245902, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1786600, Length=229, Percent_Identity=27.5109170305677, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789403, Length=236, Percent_Identity=29.2372881355932, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790861, Length=229, Percent_Identity=29.6943231441048, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI48994928, Length=223, Percent_Identity=26.9058295964126, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790436, Length=227, Percent_Identity=25.9911894273128, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1789149, Length=203, Percent_Identity=28.0788177339901, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 42849; Mature: 42718

Theoretical pI: Translated: 10.70; Mature: 10.70

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNRTDPGRRGAACPPPSRLPALRYLRWRWLRFRRSWTDTRADRMPSWSRLYLRAYLHL
CCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MSLVLTVVAVPLLALAATLSPRTVLAGFEALPGGALGVALFVIVVPALATWRWARPTWSD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
LVMVRERAIDFSGGRFHTRARESHSVILGPLARTLNALAMRMERLIEAQRDLTNGISHEL
HHHHHHHHCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLARVRFALEALRDPASDAERHAALDSIAQDVTELDELIDMSLTYARLEYSSLQSNQA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PTGLATWLETQVHDVAQLDPTKRIEMRIGVPRELRVNMDTRLMSYAIRNLLRNAGKYARS
CCHHHHHHHHHHHHHHHCCCCHHEEEEECCCHHEECCHHHHHHHHHHHHHHHHHHHHHHH
RIVIGAAAGADGGITVFVEDDGPGVPDIERERIFDAFVRLDRHTAGYGLGLAITRQVLRA
EEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
HHGNIVVTDARELSGARFEIGWPG
HCCCEEEECHHHHCCCEEECCCCC
>Mature Secondary Structure 
SGNRTDPGRRGAACPPPSRLPALRYLRWRWLRFRRSWTDTRADRMPSWSRLYLRAYLHL
CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
MSLVLTVVAVPLLALAATLSPRTVLAGFEALPGGALGVALFVIVVPALATWRWARPTWSD
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
LVMVRERAIDFSGGRFHTRARESHSVILGPLARTLNALAMRMERLIEAQRDLTNGISHEL
HHHHHHHHCCCCCCEEECCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTPLARVRFALEALRDPASDAERHAALDSIAQDVTELDELIDMSLTYARLEYSSLQSNQA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
PTGLATWLETQVHDVAQLDPTKRIEMRIGVPRELRVNMDTRLMSYAIRNLLRNAGKYARS
CCHHHHHHHHHHHHHHHCCCCHHEEEEECCCHHEECCHHHHHHHHHHHHHHHHHHHHHHH
RIVIGAAAGADGGITVFVEDDGPGVPDIERERIFDAFVRLDRHTAGYGLGLAITRQVLRA
EEEEEEECCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
HHGNIVVTDARELSGARFEIGWPG
HCCCEEEECHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 2646639; 1925016; 1495392 [H]