Click here to switch to the map view.

The map label for this gene is nhaR [H]

Identifier: 238025101

GI number: 238025101

Start: 2202506

End: 2203384

Strand: Reverse

Name: nhaR [H]

Synonym: bglu_2g17580

Alternate gene names: 238025101

Gene position: 2203384-2202506 (Counterclockwise)

Preceding gene: 238025107

Following gene: 238025100

Centisome position: 77.93

GC content: 75.54

Gene sequence:

>879_bases
ATGCTGAATTTCCGCCATTTGTACTACTACTGGGTCGTCGTGCAGGAGGGCGGCTTCGCGCGCGCGGCCGGGCGGCTCGG
GATGGCCGTGCAGACCATCAGCGCGCAGGTGCGCGAACTCGAGCGCGCGCTCGGCCACGCGCTGCTGAAGCCGGCCGGGC
GCGGCGTGACGATGACCGAAGCGGGACAGGCCGCGTTCGCGCGCGCCGACGAGATGTTCCGGATCGGCGCGCGGATCGCC
GACGACGTGCGCGCGGCGGCCGGCGGCGAGCTGGCCCGCTTCGCGATCGGCCTGACCGACGGCGTGTCGAAACTGGCCGC
GCACGCGGTGCTCGCGCCGGCGCTCGACACGCCGTCGCTGCGGCTGCTCTGCCACGAGGGCGAACTCGAGGCGCTGCTCG
CGGAACTGGCGCTGCACCGGCTCGACCTCGTGCTGGCCAGCCAGCCGGCGCCGCCGCATCCGACGCTGCGGCTCACGAGC
GAGCGGCTCGCGGCCTCGGCGGTGGACTGGTACGGGCCGGCCGCGATCGTCACCGCGGCGGCGCGCGAGCGCTTTCCCGG
CAACCTCGCGACGCTGCCGGTGCTGCTGCCCACCGCGCAGTCGCCGCTGCGCGCGCAGCTCGAGCGCAGCTTCGAGGCGC
TCGGCGTGCGGCCGAGGATCGTCGGCGAATTCGAGGACAGTGCGCTGATGGCCGTGTTCGGGGCGCGCGGGCTCGGCGTG
TTTCCGCTGGCCGAGGCCGGGGCCGGCGACGCGGCGCTGCTGCGCGGCCTGCGCCGGCTCGGGCGGGCGCAGGGCGTGGT
CGACGAGATCTACGCGATCCGCTCGCGGCGCGGCGAGCATCATCCGCTTGCCGGCAAGCTGCGCCGCCCGCCGGCCTGA

Upstream 100 bases:

>100_bases
GGACTTCGGAAAAACCAGTTTCAAGCTGAATGAACAATCGGTTTTTACGAAGTTTTCGTATCGCCTTTGCAGGCCGTCTC
GCGTTGATGCCGGGTCCATC

Downstream 100 bases:

>100_bases
ACGCCTGCCCGCCCGTCCTGCCGCACGACCCGCAGCCTGGCGGTCCGCCAGCCCGCGGCGCCGGCTCCCGGCGCGGGGCG
AGCCTCCGATCACGACCGTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Na(+)/H(+) antiporter regulatory protein [H]

Number of amino acids: Translated: 292; Mature: 292

Protein sequence:

>292_residues
MLNFRHLYYYWVVVQEGGFARAAGRLGMAVQTISAQVRELERALGHALLKPAGRGVTMTEAGQAAFARADEMFRIGARIA
DDVRAAAGGELARFAIGLTDGVSKLAAHAVLAPALDTPSLRLLCHEGELEALLAELALHRLDLVLASQPAPPHPTLRLTS
ERLAASAVDWYGPAAIVTAAARERFPGNLATLPVLLPTAQSPLRAQLERSFEALGVRPRIVGEFEDSALMAVFGARGLGV
FPLAEAGAGDAALLRGLRRLGRAQGVVDEIYAIRSRRGEHHPLAGKLRRPPA

Sequences:

>Translated_292_residues
MLNFRHLYYYWVVVQEGGFARAAGRLGMAVQTISAQVRELERALGHALLKPAGRGVTMTEAGQAAFARADEMFRIGARIA
DDVRAAAGGELARFAIGLTDGVSKLAAHAVLAPALDTPSLRLLCHEGELEALLAELALHRLDLVLASQPAPPHPTLRLTS
ERLAASAVDWYGPAAIVTAAARERFPGNLATLPVLLPTAQSPLRAQLERSFEALGVRPRIVGEFEDSALMAVFGARGLGV
FPLAEAGAGDAALLRGLRRLGRAQGVVDEIYAIRSRRGEHHPLAGKLRRPPA
>Mature_292_residues
MLNFRHLYYYWVVVQEGGFARAAGRLGMAVQTISAQVRELERALGHALLKPAGRGVTMTEAGQAAFARADEMFRIGARIA
DDVRAAAGGELARFAIGLTDGVSKLAAHAVLAPALDTPSLRLLCHEGELEALLAELALHRLDLVLASQPAPPHPTLRLTS
ERLAASAVDWYGPAAIVTAAARERFPGNLATLPVLLPTAQSPLRAQLERSFEALGVRPRIVGEFEDSALMAVFGARGLGV
FPLAEAGAGDAALLRGLRRLGRAQGVVDEIYAIRSRRGEHHPLAGKLRRPPA

Specific function: Plays a role in the positive regulation of nhaA (Probable) [H]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786202, Length=282, Percent_Identity=31.9148936170213, Blast_Score=140, Evalue=8e-35,
Organism=Escherichia coli, GI1788297, Length=255, Percent_Identity=26.2745098039216, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31128; Mature: 31128

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNFRHLYYYWVVVQEGGFARAAGRLGMAVQTISAQVRELERALGHALLKPAGRGVTMTE
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
AGQAAFARADEMFRIGARIADDVRAAAGGELARFAIGLTDGVSKLAAHAVLAPALDTPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHHHHHCCCCCCCE
RLLCHEGELEALLAELALHRLDLVLASQPAPPHPTLRLTSERLAASAVDWYGPAAIVTAA
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHCCHHHHHHHH
ARERFPGNLATLPVLLPTAQSPLRAQLERSFEALGVRPRIVGEFEDSALMAVFGARGLGV
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCC
FPLAEAGAGDAALLRGLRRLGRAQGVVDEIYAIRSRRGEHHPLAGKLRRPPA
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNFRHLYYYWVVVQEGGFARAAGRLGMAVQTISAQVRELERALGHALLKPAGRGVTMTE
CCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEC
AGQAAFARADEMFRIGARIADDVRAAAGGELARFAIGLTDGVSKLAAHAVLAPALDTPSL
CCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHEEEHHHHHHHHHHHHHHHCCCCCCCE
RLLCHEGELEALLAELALHRLDLVLASQPAPPHPTLRLTSERLAASAVDWYGPAAIVTAA
EEEEECCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECHHHHHHHHHHHCCHHHHHHHH
ARERFPGNLATLPVLLPTAQSPLRAQLERSFEALGVRPRIVGEFEDSALMAVFGARGLGV
HHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCCC
FPLAEAGAGDAALLRGLRRLGRAQGVVDEIYAIRSRRGEHHPLAGKLRRPPA
CCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8231807; 9457888; 10952301 [H]