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The map label for this gene is tlpB [H]

Identifier: 238025042

GI number: 238025042

Start: 2129206

End: 2130885

Strand: Reverse

Name: tlpB [H]

Synonym: bglu_2g16990

Alternate gene names: 238025042

Gene position: 2130885-2129206 (Counterclockwise)

Preceding gene: 238025043

Following gene: 238025041

Centisome position: 75.37

GC content: 68.57

Gene sequence:

>1680_bases
ATGGCCAACGTGTCGCCTCGCGCAAGCGCCGAACGTCGTTCCCAGCCCCCCGTCGGTGCGCGGATCACGCTCGGCAACCG
GATCCTGCTCAGCTTCGGCGTGCTGTTCGTGCTGATGCTGCTGATGGCGGGCCTGTCCTACACCCAGCTGCGCTCGATCG
ACCAGGAGACGGTCAGCATCCAGCGCGACTCGCTGCCGGGCGTCTATCTGGCCACCTCGCTGCGTGCGGCCGCCAACGAG
TCGTATACGGCGATGCAGCGGGCGATCTTCGTCGATCCCGATTCGGAGGCCTCGCGCCGCGATCTCGACCGCATCCCCGG
CATGCTGGAGTCGTTCGAGAAGCTCTCGACCGCGTACCAGAACGCCACGTTCCGCGACGAGGACCGCGCCCGCTTCGCCA
CCTTCCGCGCTGTCTACGATCGCTATCTGCCGCTTCTGGCCGACGCCGTGCAGAAGGCGCGCACGGGTGCCCATGCCGAC
GCGGTGGTGGCCTACGGGCGCGTCACGCCGGTCTGGGAGGACGTGATCCGCAATGCCAACGTGCTGGTCACCGAGAACCG
CACGTTCGCCGACCAGTCGGCGCAGATGATCCGCGAATCGGTGTACGGCACCGAGGTCACGCTCGCCACCGTGCTGGCCG
TGGTGCTGATCTGCTCGGCCGTGCTCGGCTGGCTCCTGTACCGCGCCGTGATGCGGCCGATGACCGAGCTGGTCGACGTC
CACGACGTGATGCGCACGGGCGACCTGACCCGGCGGCTCGACCTGCGCCGCCACGACGAGTTCAACATGCTCGAGACCGG
CTTCAACCGGATGGCCGACGAGCTGACCACGCTGGTCGCGCAGGCCCAGCAGTCGTCGCTGCAGGTCACCACCTCGGTGG
CCGAGATCGCCGCCACCTCGCGCGAGCAGCAGGCCACCGCCAACGAGACGGCCGCCACCACCACCGAGATCGGCGCGACC
TCGCGCGAGATCTTCGCGACTTCGCGCGACTTGCTGCGCACCATGAACGAGGTGTCGTCGGTGGCCGAGCAGTCGGCCTC
GCTCGCGGGCCTGAGCCAGAGCGGCCTCACGCAGATGGGCGAGACCATGCGCAGCGTGATGGACGCGGCCGGCTCGGTCA
ACGCCAAGCTCGCGATCCTCAACGAGAAGGCGCTCAACATCAACCAGGTGGTGGCCACCATCACGAAGGTCGCCGACCAG
ACCAACCTGCTGTCGCTGAACGCGGCGATCGAGGCCGAGAAGGCCGGCGAATACGGCCGCGGCTTCGCGGTGGTCGCCAC
CGAGATCCGCCGCCTCGCCGACCAGACCGCGGTGGCCACCTACGACATCGAGCAGACCGTCAAGGAGATCCAGTCGGCGG
TGTCGGCCGGCGTGATGGGCATGGACAAGTTCTCCGAGGAAGTGCGGCGCGGCATGCTCGACGTGCAGCAGGTGGGCTCG
CAGCTCTCGCAGATCATCCACGAAGTGCAGACGCTCGCGCCGCGCTTCCAGCTCGTCAACGAGGGCATGCAGACCCAGGC
GAGCGGCGCCGAGCAGATCACCCAGGCGCTCTCGCAGCTGTCCGAGGCGGCCCAGCAGACGGCCGAATCGCTGCGCCAGT
CGTCGCAGGCGATCGACGACCTGACGCTGGTGGCCAACGCGCTGCGCACCAGCGTGTCGCGCTTCAAGGTCGAGGCGTGA

Upstream 100 bases:

>100_bases
CCCGGGCTGTCTCGGCGGCCATAAAGAAAGTACACTTTGCTGGCTCGCGCCCGCCGGTCGGCGGCTCCTGAACGCATCTG
CAGACTACCCATATCGAAAC

Downstream 100 bases:

>100_bases
GCACCGAGGCCCGCCGCGCCATGCTGTTCCTGCTGTTCGAGCTCGACGGCGTGCGCTACGCGCTCGACGTGGCCGACGTC
GCCGAGGTGCTGCCGCTCGC

Product: putative methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MANVSPRASAERRSQPPVGARITLGNRILLSFGVLFVLMLLMAGLSYTQLRSIDQETVSIQRDSLPGVYLATSLRAAANE
SYTAMQRAIFVDPDSEASRRDLDRIPGMLESFEKLSTAYQNATFRDEDRARFATFRAVYDRYLPLLADAVQKARTGAHAD
AVVAYGRVTPVWEDVIRNANVLVTENRTFADQSAQMIRESVYGTEVTLATVLAVVLICSAVLGWLLYRAVMRPMTELVDV
HDVMRTGDLTRRLDLRRHDEFNMLETGFNRMADELTTLVAQAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGAT
SREIFATSRDLLRTMNEVSSVAEQSASLAGLSQSGLTQMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQ
TNLLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGS
QLSQIIHEVQTLAPRFQLVNEGMQTQASGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANALRTSVSRFKVEA

Sequences:

>Translated_559_residues
MANVSPRASAERRSQPPVGARITLGNRILLSFGVLFVLMLLMAGLSYTQLRSIDQETVSIQRDSLPGVYLATSLRAAANE
SYTAMQRAIFVDPDSEASRRDLDRIPGMLESFEKLSTAYQNATFRDEDRARFATFRAVYDRYLPLLADAVQKARTGAHAD
AVVAYGRVTPVWEDVIRNANVLVTENRTFADQSAQMIRESVYGTEVTLATVLAVVLICSAVLGWLLYRAVMRPMTELVDV
HDVMRTGDLTRRLDLRRHDEFNMLETGFNRMADELTTLVAQAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGAT
SREIFATSRDLLRTMNEVSSVAEQSASLAGLSQSGLTQMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQ
TNLLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGS
QLSQIIHEVQTLAPRFQLVNEGMQTQASGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANALRTSVSRFKVEA
>Mature_558_residues
ANVSPRASAERRSQPPVGARITLGNRILLSFGVLFVLMLLMAGLSYTQLRSIDQETVSIQRDSLPGVYLATSLRAAANES
YTAMQRAIFVDPDSEASRRDLDRIPGMLESFEKLSTAYQNATFRDEDRARFATFRAVYDRYLPLLADAVQKARTGAHADA
VVAYGRVTPVWEDVIRNANVLVTENRTFADQSAQMIRESVYGTEVTLATVLAVVLICSAVLGWLLYRAVMRPMTELVDVH
DVMRTGDLTRRLDLRRHDEFNMLETGFNRMADELTTLVAQAQQSSLQVTTSVAEIAATSREQQATANETAATTTEIGATS
REIFATSRDLLRTMNEVSSVAEQSASLAGLSQSGLTQMGETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQT
NLLSLNAAIEAEKAGEYGRGFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGSQ
LSQIIHEVQTLAPRFQLVNEGMQTQASGAEQITQALSQLSEAAQQTAESLRQSSQAIDDLTLVANALRTSVSRFKVEA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=471, Percent_Identity=25.4777070063694, Blast_Score=111, Evalue=1e-25,
Organism=Escherichia coli, GI1788194, Length=348, Percent_Identity=26.7241379310345, Blast_Score=104, Evalue=2e-23,
Organism=Escherichia coli, GI2367378, Length=320, Percent_Identity=24.6875, Blast_Score=89, Evalue=9e-19,
Organism=Escherichia coli, GI1788195, Length=313, Percent_Identity=27.7955271565495, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789453, Length=340, Percent_Identity=24.1176470588235, Blast_Score=86, Evalue=7e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 60969; Mature: 60838

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANVSPRASAERRSQPPVGARITLGNRILLSFGVLFVLMLLMAGLSYTQLRSIDQETVSI
CCCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRDSLPGVYLATSLRAAANESYTAMQRAIFVDPDSEASRRDLDRIPGMLESFEKLSTAYQ
HHCCCCCHHHHHHHHHHCCCHHHHHHHHEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHH
NATFRDEDRARFATFRAVYDRYLPLLADAVQKARTGAHADAVVAYGRVTPVWEDVIRNAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCC
VLVTENRTFADQSAQMIRESVYGTEVTLATVLAVVLICSAVLGWLLYRAVMRPMTELVDV
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDVMRTGDLTRRLDLRRHDEFNMLETGFNRMADELTTLVAQAQQSSLQVTTSVAEIAATS
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQQATANETAATTTEIGATSREIFATSRDLLRTMNEVSSVAEQSASLAGLSQSGLTQMG
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQTNLLSLNAAIEAEKAGEYGR
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCC
GFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QLSQIIHEVQTLAPRFQLVNEGMQTQASGAEQITQALSQLSEAAQQTAESLRQSSQAIDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLVANALRTSVSRFKVEA
HHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ANVSPRASAERRSQPPVGARITLGNRILLSFGVLFVLMLLMAGLSYTQLRSIDQETVSI
CCCCCCCCHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
QRDSLPGVYLATSLRAAANESYTAMQRAIFVDPDSEASRRDLDRIPGMLESFEKLSTAYQ
HHCCCCCHHHHHHHHHHCCCHHHHHHHHEEECCCCCHHHHHHHHCCHHHHHHHHHHHHHH
NATFRDEDRARFATFRAVYDRYLPLLADAVQKARTGAHADAVVAYGRVTPVWEDVIRNAN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHCCCC
VLVTENRTFADQSAQMIRESVYGTEVTLATVLAVVLICSAVLGWLLYRAVMRPMTELVDV
EEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
HDVMRTGDLTRRLDLRRHDEFNMLETGFNRMADELTTLVAQAQQSSLQVTTSVAEIAATS
HHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REQQATANETAATTTEIGATSREIFATSRDLLRTMNEVSSVAEQSASLAGLSQSGLTQMG
HHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
ETMRSVMDAAGSVNAKLAILNEKALNINQVVATITKVADQTNLLSLNAAIEAEKAGEYGR
HHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCCCC
GFAVVATEIRRLADQTAVATYDIEQTVKEIQSAVSAGVMGMDKFSEEVRRGMLDVQQVGS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
QLSQIIHEVQTLAPRFQLVNEGMQTQASGAEQITQALSQLSEAAQQTAESLRQSSQAIDD
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTLVANALRTSVSRFKVEA
HHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8188684; 9384377 [H]