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The map label for this gene is puuP [H]

Identifier: 238024881

GI number: 238024881

Start: 1928587

End: 1929942

Strand: Reverse

Name: puuP [H]

Synonym: bglu_2g15220

Alternate gene names: 238024881

Gene position: 1929942-1928587 (Counterclockwise)

Preceding gene: 238024882

Following gene: 238024880

Centisome position: 68.26

GC content: 68.51

Gene sequence:

>1356_bases
ATGACTCAATCCTCCCCGGCGCGGCTCGCGGCCGGCCACGAGCCGCACCTGAAGCGCGCGCTCGGTCTGCCGTCCGTGCT
GCTGTTCGGCCTTGCCTACATGGCCCCGCTGATCGTCTACGGCACCTACGGCGTGCTGGCCGGCGCGAGCCAGGACACGG
CCGCGCTCGCCTACCTGCTGGCGCTGATCGCGATCGTGTTTACCGCGCTCAGCTACGGCAAGCTCGCGCGGCTGTTCCCG
GTGGCGGGCTCGGCCTACACCTATACGCGCAAGAGCTTCAACGCGCATCTGGGCTTCCTGGTCGGCTGGGCCACGCTGCT
CGACTACTTCTTCCTGCCGATGGTGATCTGGCTGATCGGCGCGGCCTATCTGGGCGCGGCGTTCCCGTCGGTTCCGGCAT
GGATCTGGATCGTGGCGTTCATCGTGCTGACCAGCGCGCTGAACATCCTCGGCATCGAGCTGGCGACCCGCTTCAACATC
GTGCTGATGCTGGTGCAGCTCGTGATCGTGGCGCTGTTCGTGGTGCTGTGCTGCCACTACGCGCTGGCCGCGGCGGGGCC
GGGCGGGCTGGCCGCGGCGCAGCCGTTCTTCAACGCCAAGGTGCCGCTGTCGGCCACCATGGCCGGCGCCGCCATCGCCG
CGTATTCGTACCTCGGCTTCGACGCCGTCTCGACCTTGACCGAGGAAACCGTCGAACCCGAGAAGACCATCCCGCGCGCG
ATCGTGCTGATCGCGCTGATCGGCGGCGCGATCTTCGTGATCGCGGCCTATACGCTGCAGCTCGCGCATCCGGGCGCGGT
ATTCAAGGACCCCGATTCGGCCGCGTTCGAGATCGCCAAGAAAGTGGGCGGCGACGTGTTCGTGTCGGTGTTCCTCGCCG
GGCTGATCCTCGCGCAGTTCGCCTCCGGCATCTCGGCGCAGGCCAGCGTCGGCCGGCTGCTCTATGCGATGGGCCGCGAC
GAGGTGCTGCCGCGCCGGATCTTCGGCTACGTGCACCCGCGCTTTCGCACGCCGGCGCTCAACATCGGGTTCGCCGGCAT
CGTCGGGCTGATCGCGCTCAAGCTCGACGTGGCCACCTCCACCTCGTTCATCAACTTCGGCGCGTTCCTCGCGTTCACGG
CCGTCAACCTCTGCGTGATGCGCCAGTACCTGGTCACGCCGCCGGCGCAGCGCCGCTTCGGGCCGGTCGGCGGGCTGCTG
TTTCCGGCGCTCGGCGCGATCGCCGATGTCTGGCTGCTGCTGAGCCTCGAAAAATCGGCGCTCGTGCTCGGCGCGATCTG
GTTCGTGCTCGGCCTGGCCTACCTCGGCTGGCTGACGCGCGGTTTTCGCCAGGCGCCGCCTGACATCGCGGTGTGA

Upstream 100 bases:

>100_bases
CCCCGGCGTGCCGACCGGCCACGCCGTCACGCGGTGCGGCGCCGTGCAACCTGGTGTTTTGCGTTCGGACGCGCCTGGCG
CGTTCACTGGAGACCCGACC

Downstream 100 bases:

>100_bases
GGCATGCCGGCCCGGCGTGGCGGCGGTTCGCCGGGCCGCGGCCGGCATGCAGTTGCGACACCGCACGACGCATCCCGACG
GCCGTCGGCGCGCGGCCCGT

Product: putrescine importer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 451; Mature: 450

Protein sequence:

>451_residues
MTQSSPARLAAGHEPHLKRALGLPSVLLFGLAYMAPLIVYGTYGVLAGASQDTAALAYLLALIAIVFTALSYGKLARLFP
VAGSAYTYTRKSFNAHLGFLVGWATLLDYFFLPMVIWLIGAAYLGAAFPSVPAWIWIVAFIVLTSALNILGIELATRFNI
VLMLVQLVIVALFVVLCCHYALAAAGPGGLAAAQPFFNAKVPLSATMAGAAIAAYSYLGFDAVSTLTEETVEPEKTIPRA
IVLIALIGGAIFVIAAYTLQLAHPGAVFKDPDSAAFEIAKKVGGDVFVSVFLAGLILAQFASGISAQASVGRLLYAMGRD
EVLPRRIFGYVHPRFRTPALNIGFAGIVGLIALKLDVATSTSFINFGAFLAFTAVNLCVMRQYLVTPPAQRRFGPVGGLL
FPALGAIADVWLLLSLEKSALVLGAIWFVLGLAYLGWLTRGFRQAPPDIAV

Sequences:

>Translated_451_residues
MTQSSPARLAAGHEPHLKRALGLPSVLLFGLAYMAPLIVYGTYGVLAGASQDTAALAYLLALIAIVFTALSYGKLARLFP
VAGSAYTYTRKSFNAHLGFLVGWATLLDYFFLPMVIWLIGAAYLGAAFPSVPAWIWIVAFIVLTSALNILGIELATRFNI
VLMLVQLVIVALFVVLCCHYALAAAGPGGLAAAQPFFNAKVPLSATMAGAAIAAYSYLGFDAVSTLTEETVEPEKTIPRA
IVLIALIGGAIFVIAAYTLQLAHPGAVFKDPDSAAFEIAKKVGGDVFVSVFLAGLILAQFASGISAQASVGRLLYAMGRD
EVLPRRIFGYVHPRFRTPALNIGFAGIVGLIALKLDVATSTSFINFGAFLAFTAVNLCVMRQYLVTPPAQRRFGPVGGLL
FPALGAIADVWLLLSLEKSALVLGAIWFVLGLAYLGWLTRGFRQAPPDIAV
>Mature_450_residues
TQSSPARLAAGHEPHLKRALGLPSVLLFGLAYMAPLIVYGTYGVLAGASQDTAALAYLLALIAIVFTALSYGKLARLFPV
AGSAYTYTRKSFNAHLGFLVGWATLLDYFFLPMVIWLIGAAYLGAAFPSVPAWIWIVAFIVLTSALNILGIELATRFNIV
LMLVQLVIVALFVVLCCHYALAAAGPGGLAAAQPFFNAKVPLSATMAGAAIAAYSYLGFDAVSTLTEETVEPEKTIPRAI
VLIALIGGAIFVIAAYTLQLAHPGAVFKDPDSAAFEIAKKVGGDVFVSVFLAGLILAQFASGISAQASVGRLLYAMGRDE
VLPRRIFGYVHPRFRTPALNIGFAGIVGLIALKLDVATSTSFINFGAFLAFTAVNLCVMRQYLVTPPAQRRFGPVGGLLF
PALGAIADVWLLLSLEKSALVLGAIWFVLGLAYLGWLTRGFRQAPPDIAV

Specific function: Imports putrescine [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI110347453, Length=394, Percent_Identity=26.9035532994924, Blast_Score=82, Evalue=9e-16,
Organism=Escherichia coli, GI87081869, Length=449, Percent_Identity=45.43429844098, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI87082023, Length=435, Percent_Identity=42.5287356321839, Blast_Score=341, Evalue=5e-95,
Organism=Escherichia coli, GI87081708, Length=293, Percent_Identity=25.938566552901, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI87082250, Length=391, Percent_Identity=24.0409207161125, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1790653, Length=377, Percent_Identity=25.9946949602122, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1788480, Length=291, Percent_Identity=25.085910652921, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1786789, Length=329, Percent_Identity=22.4924012158055, Blast_Score=62, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17532491, Length=398, Percent_Identity=27.6381909547739, Blast_Score=92, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17533459, Length=394, Percent_Identity=24.8730964467005, Blast_Score=90, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17531343, Length=400, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI221512776, Length=431, Percent_Identity=25.754060324826, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24666159, Length=431, Percent_Identity=25.754060324826, Blast_Score=93, Evalue=4e-19,
Organism=Drosophila melanogaster, GI24667468, Length=409, Percent_Identity=26.4058679706601, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24668806, Length=419, Percent_Identity=25.0596658711217, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356285, Length=419, Percent_Identity=25.0596658711217, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24668802, Length=419, Percent_Identity=25.0596658711217, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281366235, Length=409, Percent_Identity=25.4278728606357, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI116007820, Length=409, Percent_Identity=25.4278728606357, Blast_Score=70, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 47777; Mature: 47646

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSSPARLAAGHEPHLKRALGLPSVLLFGLAYMAPLIVYGTYGVLAGASQDTAALAYLL
CCCCCCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALIAIVFTALSYGKLARLFPVAGSAYTYTRKSFNAHLGFLVGWATLLDYFFLPMVIWLIG
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAYLGAAFPSVPAWIWIVAFIVLTSALNILGIELATRFNIVLMLVQLVIVALFVVLCCHY
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALAAAGPGGLAAAQPFFNAKVPLSATMAGAAIAAYSYLGFDAVSTLTEETVEPEKTIPRA
HHHHCCCCCCHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
IVLIALIGGAIFVIAAYTLQLAHPGAVFKDPDSAAFEIAKKVGGDVFVSVFLAGLILAQF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHH
ASGISAQASVGRLLYAMGRDEVLPRRIFGYVHPRFRTPALNIGFAGIVGLIALKLDVATS
HCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
TSFINFGAFLAFTAVNLCVMRQYLVTPPAQRRFGPVGGLLFPALGAIADVWLLLSLEKSA
CHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LVLGAIWFVLGLAYLGWLTRGFRQAPPDIAV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TQSSPARLAAGHEPHLKRALGLPSVLLFGLAYMAPLIVYGTYGVLAGASQDTAALAYLL
CCCCCCHHCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH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HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]